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PODCAST

ICU Ed and Todd-Cast

Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We"ll also do deep dives on specific topics important to practicing intensive care medicine and have special guests talking about their area of expertise! This podcast is made for educational purposes. The content provided in this podcast, and in any linked materials, is not intended and should not be construed as medical advice and should not be used to diagnose or treat any medical condition

health & fitness medicine

All Episodes

57:02

TRAUMOX2, SAHARA, and mailbag

ICU Ed and Todd-Cast ·

2025/02/25

Send us a Text Message (please include your email so we can respond!) Episode 59! We finish our CCR down under coverage with TRAUMOX2 or "Early Restrictive vs Liberal Oxygen for Trauma Patients" published in JAMA by Arleth et al and then switch to SAHARA or "Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage" by English et al published in NEJM. We then frustrate Todd with questions from our mailbag, a good episode! TRAUMOX2 (pubmed): https://pubmed.ncbi.nlm.nih...

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56:42

Old/New: FLORALI and RENOVATE

ICU Ed and Todd-Cast ·

2025/02/11

Send us a Text Message (please include your email so we can respond!) Episode 58! We talk about non-invasive oxygen support and RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published in JAMA December 2024 and presented at the CCR Down Under Conference. We supplement this by first talking about FLORALI or "High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure" published in NEJM May 2015 RENOVATE (pubmed): ht...

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66:27

CCR Down Under: SCREEN with Adam Wright

ICU Ed and Todd-Cast ·

2025/01/28

Send us a Text Message (please include your email so we can respond!)Episode 57! We were excited to have on this episode Dr. Adam Wright who is a PhD in Bioinformatics to discuss SCREEN or "Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial" published by Arabi et al in JAMA 2024 and presented at the CCR Down Under Conference. A long episode but a lot of good discussionSCREEN (pubmed): https://pubmed.ncbi.nlm.nih.gov/39658862/SCREEN ...

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46:03

CCR Down Under: ADAPT-Sepsis

ICU Ed and Todd-Cast ·

2025/01/14

Send us a Text Message (please include your email so we can respond!)Episode 56! In this episode we spend a few minutes talking about making decisions on ECMO initiation but spend most of the episode talking about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized PatientsWith Suspected Sepsis" published by Dark et al in JAMA 2024 and presented at the CCR Down Under Conference.ADAPT-Sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39652885/ADAPT-Sepsis (JAMA): https://jama...

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59:58

2024 Year in Review and CCR Down Under

ICU Ed and Todd-Cast ·

2024/12/31

Send us a Text Message (please include your email so we can respond!)Episode 55 and Happy New Year! In this episode we talk broad strokes about the CCR Down Under Conference and the trials that were presented, then Todd and Eddie go over a bunch of articles from the year 2024 that they didn't have time to go over or want to re-emphasize for whatever reason. Big show and we hope you enjoy!TIGHT K: https://pubmed.ncbi.nlm.nih.gov/39215972/PROPHY VAP: https://pubmed.ncbi.nlm.nih.gov/38262428/REV...

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52:01

New/Old: BALANCE and iDIAPASON

ICU Ed and Todd-Cast ·

2024/12/17

Send us a Text Message (please include your email so we can respond!)Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas Ventilator associated pneumonia (iDIAPASON). BALANCE (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2404991BALANCE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39565030/iDIAPASON (ICM): https://link.springer.com/article/10.1007/s00134-022-06690-5iDIAPASON (pubmed): https://pubmed.ncbi.nlm.n...

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34:16

New/New-ish: IVIO and PARAMEDIC-3

ICU Ed and Todd-Cast ·

2024/12/03

Send us a Text Message (please include your email so we can respond!)Episode 53! In this episode we talk about access in patients with out of hospital cardiac arrest. Both articles are similar so we talk in depth about IVIO and then bringing PARAMEDIC-3 to round out our discussion. A good acronym discussion too, don't miss it!IVIO (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2407616IVIO (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480221/PARAMEDIC-3 (NEJM): https://www.nejm.org/doi/full/10.1...

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40:42

New/New: INTREPID and PROLABI

ICU Ed and Todd-Cast ·

2024/11/19

Send us a Text Message (please include your email so we can respond!)Episode 52! In this episode we talk about fevers in acute neurologic injury and double that up with talking about low tidal volume ventilation in patients with neurologic injuryINTREPID (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824088INTREPID (pubmed): https://pubmed.ncbi.nlm.nih.gov/39320879/PROLABI (Blue): https://www.atsjournals.org/doi/full/10.1164/rccm.202402-0375OCPROLABI (pubmed): https://pubmed.ncbi....

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22:32

LIVE @ CC Bootcamp 2024: NONSEDA

ICU Ed and Todd-Cast ·

2024/11/05

Send us a Text Message (please include your email so we can respond!)We are (were) LIVE at ACNP Critical Care Bootcamp 2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the NONSEDA trial or "Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients" by Olsen et al published in the New England Journal of Medicine February 2020NONSEDA (pubmed): https://pubmed.ncbi.nlm.nih.gov...

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55:49

FAST and IV Fluid Shortage

ICU Ed and Todd-Cast ·

2024/10/22

Send us a Text Message (please include your email so we can respond!)Episode 50! In this episode we talk about SBT frequency and "Frequency of Screening and Spontaneous Breathing Trial Techniques" by Burns et al from JAMA 2024 that was released with the ESICM conference. In our second segment, instead of another trial we talk a little bit about the IV fluid shortage happening in the United States.FAST (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824928FAST (pubmed): https://pubm...

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52:10

LIVE @ CHEST2024: Minocycline for delirium and Amio...

ICU Ed and Todd-Cast ·

2024/10/07

Send us a Text Message (please include your email so we can respond!)We are LIVE at CHEST2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about a few articles that were recently published in CHEST - "Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial" published by Dal-Pizzol et al and then "Comparative Effectiveness of Amiodarone and Lidocaine for the Treatm...

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35:26

New: Long Term Outcomes of ICU Visitation Policies

ICU Ed and Todd-Cast ·

2024/09/24

Send us a Text Message (please include your email so we can respond!)Episode 48! In this episode we talk about the long term effects of ICU visitation policies on families. Long Term Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39172240/Long Term Outcomes of Visitation (ICM): https://link.springer.com/article/10.1007/s00134-024-07577-3Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/31310297/Outcomes of Visitation (JAMA): https://jamanetwork.com/journa...

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43:13

New/Guidelines: Cognitive Dissociation and Death by...

ICU Ed and Todd-Cast ·

2024/09/10

Send us a Text Message (please include your email so we can respond!)Episode 47! In this episode we talk about a prospective observational study examining cognitive motor dissociation by Bodien et al published in the New England Journal of Medicine and then we pair that talking about the guidelines for death by neurologic criteria published in SCCM! An episode of somber but important topics!Cognitive Motor Dissociation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39141852/Cognitive Motor Dissoci...

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49:51

New/Old: TIMELESS and ANDROMEDA-Shock

ICU Ed and Todd-Cast ·

2024/08/27

Send us a Text Message (please include your email so we can respond!)Episode 46! In this episode we talk about thrombolytic windows in acute ischemic stroke from TIMELESS published by Albers et al published in the New England Journal of Medicine and then we talk about ANDROMEDA shock and serial lactates published by Hernandez et al!TIMELESS (pubmed): https://pubmed.ncbi.nlm.nih.gov/38329148/TIMELESS (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2310392ANDROMEDA-Shock (pubmed):https://pubmed....

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51:51

New/Guidelines: 1-BED and SUP Guidelines

ICU Ed and Todd-Cast ·

2024/08/13

Send us a Text Message (please include your email so we can respond!)Episode 45! In this episode we talk about sepsis bundles and the 1-BED trial by Fruend et al and discuss the stress ulcer prophylaxis guidelines just published in SCCM!1-BED (pubmed): https://pubmed.ncbi.nlm.nih.gov/38913098/SUP Guidelines: https://www.sccm.org/Clinical-Resources/Guidelines/Guidelines/SCCM-ASHP-Guideline-Prevention-of-UGIBIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure ...

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51:40

CCR24: BLING3 with Joanna Stollings

ICU Ed and Todd-Cast ·

2024/07/30

Send us a Text Message (please include your email so we can respond!)We were honored to be joined by Joanna Stollings (and honestly we needed someone to keep us grounded) to talk about BLING3 or "Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis" published in JAMA by Dulhunty et al and also released with the CCR24 conference.pubmed: https://pubmed.ncbi.nlm.nih.gov/38864155/JAMA: https://jamanetwork.com/journals/jama/fullarticle/2819971If you...

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44:52

CCR24: HEMOTION and DEFENDER

ICU Ed and Todd-Cast ·

2024/07/16

Send us a Text Message (please include your email so we can respond!)Episode 43! In this episode come close to finishing our dedicated discussion of the CCR24 trials talking about transfusion targets in TBI (HEMOTION) and dapagliflozin in critical illness (DEFENDER)!HEMOTION: https://www.nejm.org/doi/full/10.1056/NEJMoa2404360HEMOTION (pubmed): https://pubmed.ncbi.nlm.nih.gov/38869931/DEFENDER: https://jamanetwork.com/journals/jama/fullarticle/2820242DEFENDER (pubmed): https://pubmed.ncbi.nlm...

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60:06

CCR24: PROTECTION and CYCLE

ICU Ed and Todd-Cast ·

2024/07/02

Send us a Text Message (please include your email so we can respond!)Episode 42! In this episode we foray into weight lifting and body building as we talked about amino acids for kidney protection after cardiac surgery (PROTECTION) and cycling in addition to PT in mechanically ventilated adults (CYCLE). We also feature our first real ad for the Critical Care ACNP/PA Bootcamp! Details below! Bagging vs Ventilator During Cardiac Arrest: https://journal.chestnet.org/article/S0012-3692(24)00248-4...

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43:50

CCR24: Brief Overview and REVISE

ICU Ed and Todd-Cast ·

2024/06/18

Send us a Text Message.Episode 41! We continue our CCR24 recap with a brief overview and thoughts on the conference as a whole and then dive into REVISE or "Stress Ulcer Prophylaxis duringInvasive Mechanical Ventilation" published by Cook et al in NEJM June 2024. Not the sexiest of all the topics but important nonetheless (and we will get to the others soon!)REVISE: https://pubmed.ncbi.nlm.nih.gov/38875111/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be...

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66:08

CCR24: PREOXI with Kevin Gibbs

ICU Ed and Todd-Cast ·

2024/06/13

Send us a Text Message.Episode 40! In this special episode releasing at the conclusion of the PREOXI presentation at the Critical Care Reviews 2024 conference in Belfast, Ireland - we discuss the recently published PREOXI trial evaluating NIV vs facemask as pre-oxygenation for emergent endotracheal intubation. Kevin Gibbs, the first author and presenter at the conference, is our special guest. Stay tuned for our review of some of the other results from the conference!If you enjoy the sh...

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