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PODCAST

On The Pen GLP-1 News

Dave Knapp GLP-1 Industry Insider

GLP-1 medications, clearly explained, On The Pen is for curious, proactive listeners on Ozempic, Wegovy, Mounjaro, and Zepbound who want to actually understand their treatment. Each episode delivers clear context on GLP-1 science, trials, pricing, and access so you can show up to doctor visits informed, confident, and asking better questions.

health & fitness medicine

All Episodes

26:11

Wegovy Pens Recalled & Wegovy Pill Launch

On The Pen GLP-1 News ·

2026/01/06

Send us a text This episode opens the year with one of the most consequential—and complicated—weeks in GLP-1 obesity medicine. We break down three stories that, taken together, reveal why patients are increasingly reading past headlines and demanding accountability from the industry. First, we examine early-phase trial data from Arrowhead Pharmaceuticals, after headlines claimed its experimental INHBE-targeting therapy “nearly doubled” the weight loss of Zepbound. We walk through what the dat...

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00:29:14

Wegovy Pill Approved: First Ever GLP-1 Pill, As Good...

On The Pen GLP-1 News ·

2025/12/23

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00:59:05

GLP-1 Compound Legislation: States are the Next...

On The Pen GLP-1 News ·

2025/12/19

Pharma Influence & Why Patient Voices MatterLobbying Power: Eli Lilly, Novo Nordisk, and Government Access Why GLP-1 Medication Access Is at Risk Introducing Sabina Hemi & the Mission of GLP Winner Why Compounded GLP-1s Matter for Real Patients The Federal “Safe Drugs” Bill: What It Claims vs What It Does Why This Bill Raises Red Flags for Patients What Real Compounding Safety Reform Would Look Like How Compounding Pharmacies Are Actually Regulated Today Prescription Reporting vs Patient

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00:29:09

Compounded Retatrutide? What the Judge Said

On The Pen GLP-1 News ·

2025/12/16

Retatrutide is years away from FDA approval and yet the fight over access, price, control of this medication is already well underway. That's what this podcast is going to be about today. There's well over a hundred thousand people by my estimates who are already on some form of this medication today. And that should tell you enough about how disruptive this molecule is and will be. It is a game changer among game changer. We've been talking about it for three years here at On The Pen, well before

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00:50:24

Retatrutide Weight Loss: How Much At Each Dose

On The Pen GLP-1 News ·

2025/12/13

https://www.otplinks.com0:00 Welcome & today’s focus: Retatrutide and “chasing the biggest number” 1:11 On The Pen intro, live schedule (Mon/Wed/Fri) & housekeeping 2:10 How Dave first heard about retatrutide (work trip, early phase 1 data) 3:35 Flashback clip: early excitement about retatrutide phase 3 trials 4:40 Why this new retatrutide data feels different for obesity medicine 5:32 TRIUMPH-4 trial overview: obesity + knee osteoarthritis population 7:00 Headline results: 28.7% average

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00:34:00

Mounjaro vs. New Obesity Drugs: Why Wave-007 Is...

On The Pen GLP-1 News ·

2025/12/09

Episode Timeline & Main Topics 00:00 — Opening & Community Update • First week doing the podcast fully live thanks to the On The Pen community • Overview of why this week’s news is a major turning point in obesity medicine 02:30 — Introducing the “One-and-Done” Obesity Drug (Wave Life Sciences) • WVE-007 early data drops • Why this therapy is unlike GLP-1s or any nutrient-stimulated hormone • Fat loss results and lean-mass increase 06:30 — How Wave-007 Works: INHBE Gene Silencing • Mechanism

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00:29:39

GLP-1: New Metrics, New Molecules, New Prices

On The Pen GLP-1 News ·

2025/12/02

Topics We Cover:00:00 – New data from Harvard/Mass General may classify nearly 70% of adults as having obesity 03:00 – A new oral triple agonist shows record-setting absorption rates 07:00 – Fractal Health’s Revita procedure: weight maintenance after stopping GLP-1s 12:00 – Zepbound vial prices drop (full breakdown by dose) 16:00 – Dave’s personal experience switching off Mounjaro and intense hunger return 22:00 – Novo Nordisk’s EVOKE/EVOKE+ Alzheimer’s trial: what the data really means 29:00 – Why

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00:36:28

Novo Nordisk Amycretin Shocker + Semaglutide Flopper

On The Pen GLP-1 News ·

2025/11/25

Follow Us Everywhere:https://www.otplinks.com Sign up for Emails: https://www.obesity.news Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:32:02

Wegovy GLP-1 Price Novo Blinks First

On The Pen GLP-1 News ·

2025/11/18

Het Exclusive OTP Discounts! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:45:44

GLP-1 State of the Union

On The Pen GLP-1 News ·

2025/11/11

Get Exclusive OTP Savings!Https://www.otplinks.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:45:58

Lower Cost Zepbound and Wegovy? TrumpRX Announcement...

On The Pen GLP-1 News ·

2025/11/04

Exclusive OTP SavingsHTTPS://www.otplinks.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:23:55

Eli Lilly Earnings Call Recap: NEW GLP-1 GIP Peptide...

On The Pen GLP-1 News ·

2025/10/30

EXCLUSIVE SAVINGS FOR YOU!www.OTPLinks.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:29:41

Retatrutide + Tirzepatide Grey Market Clampdown + 1...

On The Pen GLP-1 News ·

2025/10/28

GET EXCLUSIVE OTP SAVINGS!www.OTPLinks.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:49:48

HLTH 2025: Obesity Care Superstar Interviews

On The Pen GLP-1 News ·

2025/10/22

VIEW EXCLUSIVE OTP SAVINGS!http://otplinks.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:29:33

TRUMP: Ozempic Will Soon be $150 in the US! Meet the...

On The Pen GLP-1 News ·

2025/10/17

GET ACCESS TO OBESITY CARE AND MEDS AND SUPPORT OTP:https://lddy.no/1ndi6 USE CODE: OTP25 VISIT ALL OUR LINKS: https://linktr.ee/manonthemounjaro Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:27:44

Wegovy and Ozempic Users: FDA's Scathing Report on...

On The Pen GLP-1 News ·

2025/10/14

Visit our Sponsors and check out EXCLUSIVE OTP Savings! www.OTPLinks.com www.tryshed.com (use code OTP25 to save 25%) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:40:26

Retatrutide News That Could Change Everything for...

On The Pen GLP-1 News ·

2025/10/07

SUPPORT OUR WORK:OTPLinks.com 💉 Story 1 — Fractyl Health’s One-and-Done Gene Therapy for Obesity Fractyl Health just dropped preclinical results showing their GLP-1 + GIP gene therapy candidate RJVA-002 produced almost 30% weight loss in mice after a single dose. I sat down with Dr. Harith Rajagopalan, CEO of Fractyl Health, to talk about how this new Rejuva® platform works, what it means for people living with obesity and type 2 diabetes, and why gene therapy might be the future of metabolic

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00:38:01

Sobriety Meets Weight Loss: The Ethan Suplee Interview

On The Pen GLP-1 News ·

2025/10/07

View All My Links: https://www.OTPLinks.com Join Ethan's Live: 2way.tv/ethansuplee Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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01:10:55

Mounjaro Hair Loss + NFL Lineman Discovers Power in...

On The Pen GLP-1 News ·

2025/10/03

otplinks.comstallybrand.com (code OTP10) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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00:42:24

Stopping Zepbound and Maintaining with Revita

On The Pen GLP-1 News ·

2025/09/30

otplinks.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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166 results

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