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PODCAST

The Optispan Podcast with Matt Kaeberlein

Optispan is a vision for what health should be. The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good. We believe that the current practice of medicine is disease care, not health care. We believe that

science

All Episodes

00:49:46

Solving the "Lack" of Anti-aging Discovery & Ranking...

The Optispan Podcast with Matt Kaeberlein ·

2024/06/18

Subscribe to our channel: https://www.youtube.com/@optispanRelated episodes: Reversing Biological Age: Have we finally found the answer?: https://youtu.be/ivP3QTyQ2d4 Matt recently attended the 52nd annual meeting of the American Aging Association in Madison, Wisconsin and met with several people doing fascinating work in the longevity field. One of these was Mark McCormick, an Assistant Professor at the University of New Mexico (UNM) Department of Biochemistry and Molecular Biology. At UNM,

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00:32:06

The UNEXPECTED Ozempic Weight Loss Body Scan Results...

The Optispan Podcast with Matt Kaeberlein ·

2024/06/13

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00:43:50

The Two New Highest Ranked Compounds For Lifespan...

The Optispan Podcast with Matt Kaeberlein ·

2024/06/11

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01:04:52

Supplement Industry Secrets: What They Aren't Telling...

The Optispan Podcast with Matt Kaeberlein ·

2024/06/06

Subscribe to our channel: https://www.youtube.com/@optispanCheck out the Sutphin Lab: https://sutphinlab.org/ Related episodes: Uncovering New Longevity Research DISCOVERIES: The Power of 3HAA Revealed: https://youtu.be/CFVQUSVJmIk People are GETTING THIS WRONG about Supplements & My Supplement List: https://youtu.be/_UXk_ynCNUs DON'T Take Resveratrol Until You Watch This Video: https://youtu.be/MmIBdqsQYfw Does this Dog Supplement Really Work to REVERSE AGE? (PART 1):

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00:52:58

Your Dog Needs Your Help. | 38 - The Dog Aging Project

The Optispan Podcast with Matt Kaeberlein ·

2024/06/04

Help keep the Dog Aging Project alive (prizes available!): https://donor-list.org/go/QGkYGQcLFLMore about the Dog Aging Project: https://dogagingproject.org/ Enroll your dog in the Dog Aging Project: https://redcap.dogagingproject.org/su... The Dog Aging Institute: dogaginginstitute.org Save the Dog Aging Project! In 2014, Matt co-founded the Dog Aging Project, an ambitious, large-scale study of canine health and longevity aimed at understanding how dogs—and, eventually, humans—age. The project

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01:05:18

Answering Your Questions on Longevity | 37 - Ask Matt...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/30

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00:55:14

Is This The Best Time to Work Out? | 36 - Longevity...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/28

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00:42:52

The Surprising Way Body Size Relates to Lifespan | 35...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/23

Subscribe to our channel: https://www.youtube.com/@optispanIs bigger always better? It depends. Throughout the human lifespan, body size plays an important role in determining health outcomes and quality of life. It's not just about body mass index, fat distribution, weight, or muscle mass: there also exists a relationship between body size and longevity across multiple species, including humans. On average, larger species seem to live longer and age more slowly—think about the fact that

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01:07:22

DON'T Take Resveratrol Until You Watch This Video |...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/21

Subscribe to our channel: https://www.youtube.com/@optispan Resveratrol is a naturally occurring polyphenolic compound found in various plants, including in the skins of grapes, blueberries, raspberries, mulberries, and peanuts. Its association with red wine has contributed to the illusion of the "French Paradox": the observation that French people have a relatively low incidence of heart disease despite a diet rich in saturated fats. If you were alive in the 2000s, you may remember

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01:40:11

How He TRANSFORMED His Health by Taking...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/16

Subscribe to our channel: https://www.youtube.com/@optispan The journey towards prioritizing one's healthspan can be a circuitous path full of triumphs, setbacks and lessons. Challenges arise and old habits rear their ugly heads. Unforeseen obstacles test our resolve. The road is rarely linear and often leads us to unexpected places. In this episode, Matt chats with former Microsoft Chief Technology Officer and one of our first Optispan Trailblazers Stuart McKee about Stuart's early

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00:53:03

The Best Strategies for Living Longer RANKED:...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/14

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00:23:36

Comparing Bryan Johnson's RAPAMYCIN DATA: INTERESTING...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/09

Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: The R-Files episode 1: https://youtu.be/czx_-DqnnrQ The R-Files episode 2: https://youtu.be/EgIy0ghrDmo The R-Files episode 3: https://youtu.be/jLV5nOenD-g The R-Files episode 4: https://youtu.be/6AjKOe-yZeM Matt Kaeberlein's ALLERGIC REACTION to Medication While on Rapamycin: https://youtu.be/6vIVj4SaBx4 Are DEXA scans ACCURATE? What YOU NEED to KNOW: https://youtu.be/SsDJZMlM1ko The Importance of Body Composition

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00:51:00

Reversing Biological Age: Have we finally found the...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/07

Subscribe to our channel: https://www.youtube.com/@optispan Matt recently exchanged a lively correspondence about biological age with Harold Katcher, cofounder of a stealth biotechnology company and inventor of E5. E5 is a compound consisting of the purified exosome fraction of blood from young piglets—in other words, young pig blood. Harold recently co-published a paper suggesting that injecting this young pig blood into rats made rats younger on several biological aging measures, including

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01:25:30

AI vs Aging: Why Wormbot-AI is the secret weapon...

The Optispan Podcast with Matt Kaeberlein ·

2024/05/02

Subscribe to our channel: https://www.youtube.com/@optispanSupport the Longevity Million Molecule Challenge: https://orabiomedical.com/shop/ No single discipline or approach holds the key to making big strides in the longevity field. Human aging is incredibly complex, and we're going to need multiple shots on goal in our pursuit of human life- and healthspan extension. At the Optispan Podcast, we're always excited to learn about the various angles researchers and founders are taking to

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00:29:27

Aging Expert Explains How Healthcare got it ALL...

The Optispan Podcast with Matt Kaeberlein ·

2024/04/30

Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: https://youtu.be/YhzgYaY7wto In April 2024, Matt delivered a presentation at a two-day congressional briefing on longevity science hosted at Washington, D.C.'s Mayflower Hotel by the Alliance for Longevity Initiatives (A4LI). Attendees included former Speaker of the House Newt Gingrich, Republican Congressman Gus Bilirakis, and Democratic Congressman Paul Tonko. We have decided to include Matt's presentation on

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00:24:27

Inside this Non-profit's AMAZING Strategy to Fight...

The Optispan Podcast with Matt Kaeberlein ·

2024/04/25

Subscribe to our channel: https://www.youtube.com/@optispan We talk a lot about the science of longevity and healthspan on the Optispan podcast—how DEXA scans work, what an optimal rapamycin dose might look like, how the intersection of optogenetics and mitochondria are helping us understand biological aging, what supplements one might consider taking and why. But the longevity field runs on way more than just science. It takes a village—a community of researchers, engineers, entrepreneurs,

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00:36:54

Guess his body fat percentage | #26 - Healthspan...

The Optispan Podcast with Matt Kaeberlein ·

2024/04/23

Subscribe to our channel: https://www.youtube.com/@optispan Related videos: The Importance of Body Composition & Ways YOU can measure it | 21 - HSM #3: https://youtu.be/gM3aYTMsqNI A DEXA (dual-energy X-ray absorptiometry) scan is an advanced imaging procedure for measuring bone density and composition. DEXA scans utilize two different energy levels of low-dose X-ray beams—one absorbed mostly by soft tissue, and the other absorbed mainly by bone—to differentiate between bone, fat, and lean

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01:17:34

How "light-sensitive" proteins are being used to fuel...

The Optispan Podcast with Matt Kaeberlein ·

2024/04/18

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00:28:02

Doctors overlook how significantly this impacts your...

The Optispan Podcast with Matt Kaeberlein ·

2024/04/16

Subscribe to our channel: https://www.youtube.com/@optispanRelated episodes: The Importance of Body Composition & Ways YOU can measure it | 21 - HSM #3: https://youtu.be/gM3aYTMsqNI We talk a lot about making a shift from reactive disease care—a 20th century healthcare mindset—to preventative and proactive health measures designed to optimize longevity and healthspan before disease sets in. Rather than waiting for chronic conditions to manifest and treating their symptoms post hoc, we

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00:51:42

These 14 Medications are linked to lower death rates...

The Optispan Podcast with Matt Kaeberlein ·

2024/04/12

Subscribe to our channel: https://www.youtube.com/@optispanRelated episodes: People are GETTING THIS WRONG about Supplements & My Supplement List | 17 - Healthspan Medicine #2: https://youtu.be/_UXk_ynCNUs Transforming Our Understanding of Healthcare Through Geroscience | 11 - LS #4: https://youtu.be/LCPvF-SlZIU We typically think of prescription drugs as targeted treatments designed to address the underlying mechanisms and biochemical pathways associated with specific diseases or

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