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PODCAST

Answers from the Lab

Mayo Clinic Laboratories

A Mayo Clinic curated podcast sharing Mayo Clinic knowledge and advancements on the state of testing, science, and people who are making it happen behind the scenes.

health & fitness medicine

All Episodes

11:42

A New Year with Familiar Viruses: Bill Morice, M.D.,...

Answers from the Lab ·

2024/01/11

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to welcome the new year and discuss the increase of respiratory viruses.Their discussion includes:The increasing number of COVID-19 and influenza cases across the United States.The endemic state of COVID-19 and tools for prevention.The continued need to protect public

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8:41

Lipid assay improves cardiovascular risk prediction:...

Answers from the Lab ·

2024/01/04

Jeff Meeusen, Ph.D., explains how Mayo Clinic Laboratories' new MI-Heart Ceramides assay helps guide the management of patients with mildly to moderately high cholesterol. The test measures levels of lipids beyond cholesterol that boost cardiovascular risk.Show notes(00:31)Could you provide us a little bit about your background? (01:20)Could you give us a brief overview of this assay? (02:45)What patients should have this test and when should it be performed? (04:25)Could you talk a little

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7:10

Test helps identify elusive central nervous system...

Answers from the Lab ·

2024/01/02

Robin Patel, M.D., explains how a new Mayo Clinic Laboratories' assay can identify central nervous system pathogens that standard tests fail to detect. Rapid, precise diagnosis is essential to preventing long-term effects from these infections.Show notesSpeaker 3: (00:32) Please give us a brief introduction of yourself and your role at Mayo Clinic. Speaker 3: (01:44) Could you please expand a bit on this newly developed sequencing assay — which is a shotgun metagenomic test on CSF — and

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13:24

Unique testing helps identify cause of sudden cardiac...

Answers from the Lab ·

2023/12/28

Linnea Baudhuin, Ph.D., and Kate Kotzer, M.S., CGC, describe how Mayo Clinic Laboratories' postmortem genetic tests can provide answers after a sudden unexplained cardiac death. Test results are important for managing family members' risk for cardiovascular disease.Show notes(00:32) Would each of you share a little bit about yourselves and your backgrounds? (01:13) Could you provide us with an overview of these new tests? (02:31) Can you expand on why these postmortem cardiac tests are so

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10:17

Assay finds genetic cause of low bile flow: Devin...

Answers from the Lab ·

2023/12/26

Devin Oglesbee, Ph.D., explains how Mayo Clinic Laboratories' cholestasis gene panel identifies mutations that cause low flow of bile from the liver. Test results help guide treatment decisions that can prevent liver damage.Show notes(00:32) Could you please provide us a little information about your background? (01:46) Could you please give the audience a brief overview of this assay? (03:45) Which patients should have this testing and when should it be performed? (06:39) How are the

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13:17

The Past, Present, and Future of Diagnostics: Bill...

Answers from the Lab ·

2023/12/21

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to reflect on key moments from 2023 and to discuss what may lie ahead in 2024.Their discussion includes:A look back at impactful events from 2023 in laboratory medicine and diagnostics.What’s top of mind today heading into the holidays.Speculating about

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17:42

Assay identifies biomarker of autoimmune encephalitis...

Answers from the Lab ·

2023/12/19

Antibody against the GABA-A receptor is a biomarker of autoimmune encephalopathy that occurs across the lifespan, and disproportionately affects children. In this test-specific episode of the "Answers From the Lab" podcast, Andrew McKeon, M.B., B.Ch., M.D., explains how Mayo Clinic Laboratories' GABA-A receptor antibody assay aids diagnosis of this serious but treatable condition.Show notes(00:32) Could you provide a little information on your role here at Mayo Clinic? (01:11) Can you give

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15:58

Milestone Treatments for Sickle Cell Disease: Bill...

Answers from the Lab ·

2023/12/14

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the U.S. Food and Drug Administration’s (FDA) recent approval of two gene therapies for sickle cell disease.Their discussion includes:The cause and characteristics of sickle cell disease.How the new cell-based gene therapies, Casgevy and Lyfgenia,

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16:21

Panel offers proactive drug monitoring for IBD: Maria...

Answers from the Lab ·

2023/12/12

Maria Willrich, Ph.D., and Melissa Snyder, Ph.D., describe Mayo Clinic Laboratories' panel for proactive therapeutic drug monitoring of patients with inflammatory bowel disease. The panel expands options for clinicians assessing patients' response to the drugs infliximab and adalimumab.(00:32) Could you provide a little bit of background information about yourselves? (02:18) Would you give the audience a brief overview of the assay? (04:18) Which patients should have this testing and when

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13:22

Comments on the FDA’s Proposed Rule: Bill Morice,...

Answers from the Lab ·

2023/12/07

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the U.S. Food and Drug Administration’s (FDA) proposed rule on laboratory-developed tests (LDTs) and the comments Mayo Clinic submitted to the FDA.Their discussion includes:How Mayo Clinic responded in its comments to the FDA on the proposed rule

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11:12

Protecting Against Winter Respiratory Viruses: Bill...

Answers from the Lab ·

2023/11/30

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss current respiratory virus activity and the importance of staying up-to-date on preventive vaccines. Their discussion includes:The current outlook on COVID-19 cases and the importance of remaining vigilant with prevention efforts.The respiratory

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15:42

Congressional and Federal Updates: Bill Morice, M.D.,...

Answers from the Lab ·

2023/11/23

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the one-year delay to clinical laboratory payment cuts recently passed by Congress and the importance of responding to the FDA’s proposed rule on laboratory-developed tests.Specific discussion points include:How Congress passed the short-term

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14:12

Perspectives from Washington, D.C.: Bill Morice,...

Answers from the Lab ·

2023/11/16

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss key takeaways from Dr. Morice’s recent visit in Washington, D.C. Their discussion includes:How device manufacturers are evolving and collaborating within the changing landscape.The importance of submitting comments in response to the FDA’s

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10:53

RNA test identifies large B-cell lymphoma subtypes:...

Answers from the Lab ·

2023/11/14

Lisa Rimsza, M.D., explains how Mayo Clinic Laboratories' unique PM3CX test can accurately define subtypes of large B-cell lymphoma. Precise diagnosis is critical to choosing appropriate chemotherapy for these cancers.Speaker 2: (00:32) Could you provide a brief background about yourself? Speaker 2: (01:12) Would you give us an overview of the PM3CX test? Speaker 2: (03:02) Which patients should have this testing? Speaker 2: (05:14) Is this test qualitative and RNA? Speaker 2:

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10:40

Safeguards for AI in Healthcare: Bill Morice, M.D.,...

Answers from the Lab ·

2023/11/09

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss strategies for responsible innovation and how new standards for artificial intelligence (AI) safety will impact laboratory medicine and diagnostics.Their discussion includes:Highlights of the Executive Order issued by President Biden on Oct. 30

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15:16

A Possible Cure for Sickle Cell Disease: Bill Morice,...

Answers from the Lab ·

2023/11/02

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the recent news of a possible cure for sickle cell disease, as well as gene editing therapies and their impact on the laboratory. Their discussion includes:Characteristics of sickle cell disease and current testing and treatment

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14:29

Opportunities Around At-Home Testing: Bill Morice,...

Answers from the Lab ·

2023/10/26

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the role and expansion of at-home testing. Their discussion includes:How home test kits for COVID-19 led to the expansion of at-home tests and telehealth options across the health industry.Understanding from a laboratory perspective the best use of

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13:10

How AI Can Add Value to Laboratory Medicine: Bill...

Answers from the Lab ·

2023/10/19

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss how artificial intelligence (AI) has become a disruptive technology in the field of laboratory medicine, and how it can add value to patient care.Their discussion includes:How the conversation around AI and laboratory medicine began, and how it

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11:44

Transformative Technologies: Bill Morice, M.D., Ph.D.

Answers from the Lab ·

2023/10/12

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss current focus areas found across the diagnostics industry and what transformative technologies are being explored around the world.Their discussion includes:What international laboratories and diagnostics companies are working on during this

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11:45

Proposed Regulations for Laboratory Developed Tests:...

Answers from the Lab ·

2023/10/05

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the U.S. Food and Drug Administration’s (FDA) recently proposed rule that if finalized, would phase out its current enforcement discretion used for laboratory developed tests (LDTs), and regulate all laboratory tests as medical devices regardless

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