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PODCAST

Metabolism Made Easy

A J Ghalayini, Ph.D.

This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at: https://medbiochem.org/ Check out my podcast on YouTube below: https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn&si=Nu2LkpYOjHPZpxd5 These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph.D. Bio for Dr. Ghalayini: Dr. Ghalayini received his Ph.D. in Biochemistry from the

education courses

All Episodes

00:02:09

Regulation of Acetyl CoA Carboxylase

Metabolism Made Easy ·

2023/05/02

This pocast covers the regulation of the Rate-limiting enzyme in fatty acid synthesis, Acetyl CoA Carboxylase allosterically, and by covalent modification. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:05:26

Regulation of Cholesterol Biosynthesis

Metabolism Made Easy ·

2023/04/24

This podcast covers the regulation of HMG CoA Reductase by hormones, covalent modification, cytoplasmic cholesterol, and statins. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:02:04

What is Metabolism?

Metabolism Made Easy ·

2023/04/10

This podcast defines metabolism and its two distinct components: anabolism and catabolism. The major compartments involved in both are also covered. If you like this podcast, feel free to donate to the podcast. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:03:04

Dietary Components: 12 distinct uses

Metabolism Made Easy ·

2023/04/03

This podcast covers the distinct uses of glucose, fatty acids, and amino acids and their unique roles in metabolism. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:06:10

What happens when we fast: The plasma sources of...

Metabolism Made Easy ·

2023/03/20

This podcast covers the key role of the liver and adipose tissue in providing energy sources to the plasma during fasting. The liver is the provider of glucose and fatty acids, while adipose tissue provides fatty acids to the bloodstream. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:04:18

What a ketogenic diet teaches us about metabolism?

Metabolism Made Easy ·

2023/03/10

While following a ketogenic diet, maintenance of plasma glucose is essential for several tissues. The amino acids derived from dietary proteins will provide the carbon skeletons for glucose synthesis by the liver, while the triacylglycerols from dietary fat will provide the energy for various tissues through Beta-oxidation of fatty acids. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:03:09

3 GPCRs: 4 second messengers

Metabolism Made Easy ·

2023/03/06

This podcast covers the production of cAMP by activation of either the beta-adrenergic receptor or the glucagon receptor as well as the activation of the alpha1-adrenergic by epinephrine to produce IP3, DG and calcium. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:02:59

The 3 Stages of Catabolism

Metabolism Made Easy ·

2023/02/22

This podcast covers the 3 stages of catabolism from the intestinal lumen to inside the cell. The energy output is mostly produced in the mitochondrial catabolic pathways. Similar content is available at: https://medbiochem.org/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:04:02

Major Metabolic Pathways for Carbohydrates and Fat

Metabolism Made Easy ·

2023/02/09

This podcast covers the major pathways for catabolism of glucose and fatty acids, including the ATP output from their complete degradation to CO2. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:02:19

NSAIDS, Cortisol and Inflammation

Metabolism Made Easy ·

2023/01/18

This podcast covers the target enzymes of NSAIDS and cortisol and their respective effects on inflammation. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:04:40

Covalent Modification II: Regulation of Enzymes by...

Metabolism Made Easy ·

2023/01/13

This podcast covers the effect of phophorylstion/dephosphorylation by protein kinases and phosphatases on enzyme activity. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:04:06

Insulin, phosphatases and the well-fed state

Metabolism Made Easy ·

2023/01/04

This podcast covers the activation of the Insulin receptor resulting in activation of an intracellular protein phosphatase. The deposphorylation of eight enzymes is also covered. This dephosphorylation results in profound effects on carbohydrate, lipid and protein metabolism. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:05:44

Insulin Effects in 6 minutes

Metabolism Made Easy ·

2022/12/20

This podcast describes the key tissue effects of insulin in the well-fed state including its effects on liver, muscle and adipose tissue. Also covered are the effects of insulin on regulating key enzymes involved in carbohydrate and lipid metabolism. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:05:41

Digestion, Reassembly, Absorption, and Storage of...

Metabolism Made Easy ·

2022/12/08

This podcast describes the digestion, reassembly, absorption and storage of dietary Triacylglycerol including the role of pancreatic lipase and lipoprotein lipase. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:03:57

FASTING, Glucagon and Liver Glucose Ouput

Metabolism Made Easy ·

2022/11/25

This podcast describes the liver output of glucose during fasting and its regulation by glucagon. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:00:59

Covalent Modification of Enzymes

Metabolism Made Easy ·

2022/11/16

This podcast covers the phosphorylation of enzymes by protein kinases that modify specific hydroxyl residues in enzymes. This content may be useful to premedical and medical students. Similar biochemistry content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:03:24

Reduction of Plasma Cholesterol by Statins

Metabolism Made Easy ·

2022/09/15

This podcast describes the specific mechanism by which statins reduce plasma cholesterol. The reduction of cholesterol synthesis by statins in effect, will result in the upregulation of the LDL receptor and increased uptake of LDL from plasma. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:04:40

Insulin Effects on Liver, Muscle and Adipose Tissue

Metabolism Made Easy ·

2022/09/15

This podcast describes the specific metabolic effects of insulin on liver, muscle and adipose tissue. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:10:17

Adenylate Cyclase: 7 Key Features

Metabolism Made Easy ·

2022/09/03

This podcast covers the key components of the adenylate cyclase system including receptor activation, G-protein involved, activation of adenylate cyclase , production of cAMP, activation of PKA and termination of the actions of cAMP . Also included is a historical perspective of the discovery of G-proteins the adeylate cyclase system. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:01:46

Reversal of PKA Effects by Insulin

Metabolism Made Easy ·

2022/09/01

This podcast describes the activation of the a phosphoprotein phosphatase by insulin. Also check out the podcast below for insulin's effects on specific enzymes: https://anchor.fm/a-j-ghalayini/episodes/Insulin-and-Enzyme-Dephosphorylation-e1mb74a --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

223 results

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