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PODCAST

Springer Nature

Springer Nature

Welcome to the Springer Nature Soundcloud page! Here you will find several podcasts from our journals across a range of scientific subjects, including Gene Pod, ModPath Chat, Pediapod, Hereditypod and Brainpod.

science

All Episodes

00:24:04

Life in the cold

Springer Nature ·

2022/12/21

Dr Emiliano Trucchi (Marche Polytechnic University) and Dr Céline Le Bohec (University of Strasbourg; Monaco Scientific Center) discuss the genetic basis of cold adaptation in the emperor penguin. Céline also shares her experience of visiting Antarctica. This episode explores the recent Heredity paper: “Selection-driven adaptation to the extreme Antarctic environment in the Emperor penguin” https://www.nature.com/articles/s41437-022-00564-8

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00:10:07

Neutrophil function in pediatric lupus.

Springer Nature ·

2022/11/28

Systemic lupus erythematosus (SLE) causes significant long-term morbidity and mortality, particularly in children. There is some evidence that the innate immune system, in particular neutrophil activity, can be compromised in adult-onset lupus. Yet there is a paucity of data on neutrophil activity in pediatric SLE. This month on Pediapod, we join Early Career Investigator, Rakesh Kumar Pilania, an assistant professor at the postgraduate Institute of Medical Education and Research in Chandigarh,

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00:17:47

Morphologic Feature Guiding Discovery of Driver...

Springer Nature ·

2022/11/24

Adenoid Ameloblastoma is a very rare benign odontogenic tumor characterized microscopically by epithelium resembling conventional ameloblastoma, with additional duct-like structures, epithelial whorls, and cribriform architecture. Dentinoid deposits, clusters of clear cells, and ghost-cell keratinization may also be present.These tumors do not harbor BRAF or KRAS mutations and their molecular basis appears distinct from conventional ameloblastoma but remains unknown. Dr. Carolina Cavalieri Gomes

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00:30:52

The cradle of cat domestication

Springer Nature ·

2022/11/24

In this episode, Dr Sara Nilson (University of Nebraska–Lincoln), Dr Jared Decker (University of Missouri) and Prof. Leslie Lyons (University of Missouri) discuss their quest to find the geographical origins of cat domestication. This episode explores the recent Heredity paper: “Genetics of randomly bred cats support the cradle of cat domestication being in the Near East” https://www.nature.com/articles/s41437-022-00568-4

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00:25:54

Risk Stratification for SLNB in Melanoma

Springer Nature ·

2022/11/10

Although prophylactic lymph node dissections do not improve survival, the prognostic implications of a positive sentinel node and the benefi ts of removing nodal metastases for loco-regional disease control remain important. There is a strong interest in novel approaches that can improve patients’ selection for sentinel lymphnode biopsies (SLNB) given that 85% of these procedures are negative and non-therapeutic. The host discusses with Dr. Alexander Meves his recent review in Modern Pathology on

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00:09:29

Sex-dependent risk factors for PTSD: a prospective...

Springer Nature ·

2022/11/01

After a traumatic event, women are more likely to be diagnosed with post-traumatic stress disorder, or PTSD. Research has been conducted on what might be causing this higher rate of diagnoses; for instance, perhaps women had more cumulative trauma in their lives than the men in question. But scientists say that even taking prior childhood trauma into account, women are still diagnosed at a higher rate than men. Alyssa Roeckner is a neuroscience PhD candidate at Emory University, she’s in the lab of

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00:29:59

Flat urothelial lesions of the urinary bladder: Who...

Springer Nature ·

2022/10/27

Flat lesions of the urothelium with histologic features that falls short of the threshold for urothelial carcinoma in situ (CIS) remains a challenging problem in diagnostic surgical pathology. Among these are flat urothelial hyperplasia, urothelial dysplasia, and atypia of unknown significance; lesions that have struggled under evolving classifications, changing criteria, and limited clinical actionability, all confounded by the recognized lack of diagnostic reproducibility. In this episode of

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00:17:46

Connecting the toads

Springer Nature ·

2022/10/26

In this episode, Dr Paul Maier tells us about his research on the landscape genetics of the Yosemite toad, which only inhabits high-altitude meadows in California’s Sierra Nevada Mountains. This episode explores the recent Heredity paper: “Landscape genetics of a sub-alpine toad: climate change predicted to induce upward range shifts via asymmetrical migration corridors” https://rdcu.be/cYehZ

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00:14:54

The social epidemiology of adolescent problematic...

Springer Nature ·

2022/10/24

95% of adolescents in the US have access to a smartphone and 45% report being online "almost constantly". Beyond the general time spent on screens, the control over usage and the interference into other activities are also important considerations and could reflect problematic screen use. This week on Pediapod, we meet Early Career Investigator, Professor Jason Nagata from the University of California, San Francisco to discuss his recent study of the sociodemographic correlates of problematic

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00:17:54

Radio-Resistant Prostate Carcinoma: “Cribriform”...

Springer Nature ·

2022/10/13

Locally recurrent prostate cancer from 53 patients that failed radiation therapy and underwent salvage radical prostatectomy was analyzed for clinicopathological and genomic characteristics. Most radiorecurrent tumors were enriched in cribriform morphologies (invasive cribrifom PCa and intraductal carcinoma with cribriform pattern) and demonstrated potentially targetable genomic alterations (defects in DDR genes: TP53, BRCA2, PALB2, ATR etc.). The guest, Dr. Rajal Shah of UTSW, discusses how

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00:18:09

Sociality in mammals

Springer Nature ·

2022/10/05

Social interactions play an essential role in the lives of many animals. But how do we disentangle the genetic and non-genetic factors influencing sociality? In this episode, Dr Irene Godoy (Bielefeld University) tells us about her research on sociality in capuchin monkeys. This episode explores the recent Heredity paper: “Genetic, maternal, and environmental influences on sociality in a pedigreed primate population” https://www.nature.com/articles/s41437-022-00558-6

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00:14:23

How neonatologists' views on the Baby Doe regulations...

Springer Nature ·

2022/09/29

The Baby Doe Regulations, which regulate the provision of life-sustaining treatment to seriously ill neonates, caused a stir amongst neonatologists when they were first enacted in the 1980s. The fear at the time was that they would restrict their ability to provide optimal care to seriously ill patients by mandating the use of aggressive treatments in all but futile cases, irrespective of a patient's quality of life. In this episode, we meet Early Career Investigator Katherine Guttman from the

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00:17:58

The Stanford Experience in Implementation of the...

Springer Nature ·

2022/09/29

Establishing an efficient and standardized workflow for performing molecular classification on ECs, and reporting both the molecular and histologic findings in an integrative manner, is imperative. Dr. Brooke Howitt discusses with the host her institution’s effort to implement rapid and routine molecular classification on all ECs diagnosed at Stanford.

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00:21:19

Expanding the clinico-pathological spectrum of SDH...

Springer Nature ·

2022/09/15

Most succinate dehydrogenase (SDH)-deficient RCCs demonstrate classic morphology characterized by bland eosinophilic cells with intracytoplasmic inclusions. Increasingly, “variant” morphologic features are recognized. Drs. Anthony Gill and Talia Fuchs discuss with the host their findings in a recent publication in Modern pathology where features such as high-grade nuclear features, necrosis, papillary, solid, and tubular architecture are present. These features appear to be associated with more

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00:09:47

Sex differences in appetitive and reactive aggression

Springer Nature ·

2022/09/06

Maladaptive aggression, while not a diagnosable neuropsychiatric disorder on its own, often presents as an important comorbid condition with other neuropsychiatric disorders. But while both men and women can and do display aggression, there’s been a bias to thinking of aggression, in both its adaptive and maladaptive forms, as a male behavior. Sam Golden is an assistant professor at the University of Washington in the department of biological structure and also has an appointment in the Center for

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00:22:01

High Risk and Selected Benign Breast Lesions on Core...

Springer Nature ·

2022/09/01

The vast majority of image-detected breast abnormalities are currently diagnosed by percutaneous core needle biopsy (CNB). While management of frankly malignant lesions diagnosed by CNB is now well-defined, there is less consensus on the optimal management of high-risk and selected benign lesions diagnosed by CNB. In this episode, Dr. Benjamin Calhoun from University of North Carolina in Chapel Hill eloquently discusses the evidence for and against immediate excision of such lesions.

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00:18:01

Activity, sleep, and mitochondrial variation

Springer Nature ·

2022/08/24

Can the sleep and activity patterns of fruit flies help us better understand human metabolic disorders? It’s a big question, and one that we are going to touch upon today, as we hear from Dr Pedro Vale, Katy Monteith (University of Edinburgh), and Lucy Anderson. This episode also touches upon the undergraduate research experience, first publications, and the benefits of peer-review. This episode explores the recent Heredity paper: “Variation in mitochondrial DNA affects locomotor activity and

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00:10:20

Placental transfusion during neonatal resuscitation...

Springer Nature ·

2022/08/23

For depressed preterm neonates, initiating positive pressure ventilation is the most important factor in facilitating transition. Therefore the recommendation for depressed neonates is to immediately cut the umbilical cord and begin resuscitation. However, many studies have shown that delaying the clamping of the umbilical cord also benefits preterm infants by increasing a neonate's blood volume, oxygenation and circulatory stabilisation, thus aiding transition. In this episode, we meet Early

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00:21:31

Are ancillary studies of any utility in risk...

Springer Nature ·

2022/08/18

Modern Pathology have recently launched a new series of reviews addressing controversial issues in pathology. In this episode of ModPath CHAT, Dr. Elizabeth Montgomery, a world renowned expert in gastrointestinal pathology gives her point of view on the utility of ancillary testing for risk stratification of Barrett’s esophagus and dysplasia.

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00:17:55

Ki-67 assessment in pancreatic neuroendocrine...

Springer Nature ·

2022/08/04

Ki-67 assessment is a key step in the diagnosis of neuroendocrine neoplasms (NENs) from all anatomic locations. The application of digital pathology coupled with machine learning has been shown to be highly accurate and reproducible for the evaluation of Ki-67 in NENs. The guest, Dr. Claudio Luchini from the University of Verona in Italy, discusses his recently published systematic review on the subject of Ki-67 assessment in pancreatic NENs (PanNENs) employing digital image analysis (DIA). The

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