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PODCAST

Pharmacy to Dose: The Critical Care Podcast

Pharmacy to Dose: The Critical Care Podcast discusses critical care and its pharmacotherapy in a fun and entertaining manner. Each episode features a special guest, a subject matter expert, talking with host Nick Peters.

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All Episodes

27:14

2023 ACCP Annual Meeting Day 1 & 2 Mini Recap

Pharmacy to Dose: The Critical Care Podcast ·

2023/11/13

2023 ACCP Annual Meeting Day 1 & 2 Mini Recap Nick discusses his highlights, thoughts, and even suggestions from Day 1 & 2 of the 2023 ACCP Annual Meeting in Dallas, TX. https://www.accp.com/meetings/am23/index.aspx @PharmacyToDose PharmacyToDose@Gmail.Com PharmacyToDose.com Learn more about your ad choices. Visit megaphone.fm/adchoices

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90:18

AVP: All Vasopressin Podcast

Pharmacy to Dose: The Critical Care Podcast ·

2023/11/09

AVP: All Vasopressin Podcast Special Guests: Seth Bauer, PharmD, FCCM, FCCP, BCCCP Gretchen Sacha, PharmD, BCCCP 05:42 – Historical use/mechanism of action 14:00 – Septic shock guideline recommendations 18:45 – When to add vasopressin? 26:55 – Vasopressin dosing 38:52 – Predicting vasopressin response 48:55 – Use in special populations 61:25 – Discontinuation 67:39 – Cost considerations 72:48 – Use in other shock states 77:00 – Future research/Take-home points Reference

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43:17

Trial of the Week: Rivers EGDT in Sepsis

Pharmacy to Dose: The Critical Care Podcast ·

2023/11/07

Trial of the Week: Rivers EGDT in Sepsis Special Guest: Rob Maclaren, PharmD, MPH, MCCM, FCCP I’m joined by Rob Maclaren to discuss the 2001 NEJM study “Early goal-directed therapy in the treatment of severe sepsis and septic shock.” We discuss the historical care of sepsis, mortality rates prior to this study, and use of critical care bundles before highlighting all the findings from the Rivers EGDT in sepsis trial. Then we review if one component is more important than others, break down the

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90:24

2023 NACCT PharmD Research Highlights

Pharmacy to Dose: The Critical Care Podcast ·

2023/11/03

2023 North American Congress of Clinical Toxicology (NACCT) Pharmacist-featured Research Highlights 02:36 – “Association between daily high temperature and copperhead envenomations reported to a regional poison center” ft. Jimmy Leonard, PharmD, DABAT 18:22 – “Persistent complications following snake envenomation: results of a specialized snake post-discharge clinic” ft. Erin Ryan, PharmD 31:56 – “Evaluation of large-scale, interactive simulation in poison management & drug abuse course” ft

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53:49

CRRT Trials of the Week: RENAL & IDEAL-ICU

Pharmacy to Dose: The Critical Care Podcast ·

2023/10/31

CRRT Trials of the Week: RENAL & IDEAL-ICU Special Guest: Linda Awdishu, PharmD, MAS Linda Awdishu joins me to highlight two landmark studies related to the use of continuous renal replacement therapy (CRRT) in the critically ill. We discuss renal replacement therapy, compare modalities, and review the history of CRRT as an introduction. Then we review two studies: “Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients: RENAL study” published in 2009 and “Timing of

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83:24

Pulmonary Hypertension Part II

Pharmacy to Dose: The Critical Care Podcast ·

2023/10/31

Pulmonary Hypertension Part II Special Guest: Zach Smith, PharmD, BCPS, BCCCP, FCCP 04:03 – Intro/Diagnosis/Classification 14:30 – Treatment overview 24:00 – CCB 30:30 – PDE5i/ERA/GCS 40:00 – Prostacyclins 46:40 – RV failure in the ICU 64:30 – Role of PharmD/Take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/10/pulmonary-hypertension-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit

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32:08

Trial of the Week: AID-ICU

Pharmacy to Dose: The Critical Care Podcast ·

2023/10/20

Trial of the Week: AID-ICU Special Guest: Grace Erdman, PharmD Grace Erdman, 2023 Pharmacy to Dose Award Winner, joins to discuss “Haloperidol for the treatment of delirium in ICU patients: AID-ICU trial” published in NEJM in 2022. We review studies that led to the AID-ICU study, discuss difficulties with delirium research, deep-dive into the AID-ICU trial, compare treatment in hyper-, and hypoactive delirium, research priorities moving forward, and much more. Reference

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46:04

Trial of the Week: SPLIT

Pharmacy to Dose: The Critical Care Podcast ·

2023/10/20

Trial of the Week: SPLIT Special Guest: Anthony Hawkins, PharmD, FCCM, BCCCP Anthony Hawkins joins me to highlight the “Effect of a Buffered Crystalloid Solution vs. Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial” published in JAMA. We compare the composition of different crystalloids, review pertinent trials published prior to this study, discuss the findings from the SPLIT RCT, what is the best primary outcome in these studies,

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33:51

Trial of the Week: CRASH-3

Pharmacy to Dose: The Critical Care Podcast ·

2023/10/06

Trial of the Week: CRASH-3 Special Guest: Ruben Santiago, PharmD, BCPS, BCCCP Ruben Santiago joins me to discuss the landmark article “Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3)” published in Lancet. We review the history of TXA use in trauma, what the CRASH-3 study ultimately found, how does this compare to previous studies, what are guideline recommendations, applying this info in the

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92:15

July 2023 Literature Review Series

Pharmacy to Dose: The Critical Care Podcast ·

2023/10/05

Literature Review Series July 2023 Special Guests: Chris Bollinger, PharmD, MBA Hannah Davis, PharmD 04:05 – Featured Articles 44:35 – Cardiology 60:30 – Hematology 65:20 – Pulmonary 76:00 – PharmD 82:27 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2023/10/july-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

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47:24

Trial of the Week: UFH v. LMWH for Trauma VTE...

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/29

Trial of the Week: UFH v. LMWH for Trauma VTE Prophylaxis Special Guest: Brandon Hobbs, PharmD, BCPS, BCCCP, FCCM Brandon Hobbs joins to discuss the landmark article “A comparison of low-dose heparin with low-molecular-weight heparin as prophylaxis against venous thromboembolism after major trauma” published in the New England Journal of Medicine. We review the history of VTE prophylaxis in trauma, what this study ultimately found, how long did it impact practice, what regimen is

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74:17

ECPR

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/29

Extracorporeal Cardiopulmonary Resuscitation (ECPR) Special Guests: Caitlin Brown, PharmD, BCCCP, FCCM Patrick Wieruszewski, PharmD, BCCCP 04:22 – Definition/History of use 06:48 – ECPR vs. ACLS 11:40 – ECPR research 22:00 –VA ECMO overview 24:02 – Ideal patients/Contraindications 30:52 – ECPR overview from presentation to cannulation 41:15 – Pharmacotherapy in longer ECPR cardiac arrests 49:00 – ECPR post-resuscitation care 50:42 – Guideline recommendations 52:50 – Post-cannulation acute

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38:27

Trial of the Week: Pharmacist Impact and MRC-ICU Score

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/22

Trial of the Week: Impact of Pharmacists & MRC-ICU Score Special Guest: Andrea Sikora, PharmD, MSCR, BCCCP, FCCM Andrea Sikora joins me to discuss her study “Impact of Pharmacists to Improve Patient Care in the Critically Ill: A Large Multicenter Analysis Using Meaningful Metrics with the MRC-ICU Score” published in Critical Care Medicine. We review what the MRC-ICU scoring tool is, evidence up to this point, where it’s been implemented, what did this study show, where do we go from here, how to

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78:42

Acute Coronary Syndromes

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/21

Acute Coronary Syndromes (ACS) Special Guest: Nick Servati, PharmD, BCCP 04:55 – Pathophysiology/Clinical presentation 12:40 – “MONA” myths 20:05 – P2Y12 pretreatment 24:25 – Thrombolytics in ACS 30:35 – Anticoagulation 38:55 – Vasopressors/Inotropes 49:50 – IV antiplatelet agents 60:10 – STEMI pharmacotherapy checklist 66:00 – Future research/Take-home points Reference

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81:34

June 2023 Literature Review Series

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/21

Literature Review Series June 2023 Special Guest: Beau Blake, PharmD 03:50 – Featured Articles 30:40 – Cardiology 43:10 – PADIS 48:15 – Prostacyclins 51:20 – Infectious Diseases 63:10 – PharmD 70:15 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2023/09/june-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

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33:26

Trial of the Week: Linezolid v Daptomycin in VRE BSI

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/20

Trial of the Week: Linezolid v Daptomycin in VRE BSI Special Guest: Nick Britt, PharmD, MS, BCPS, BCIDP Nick Britt joins to highlight his first-author research comparing the use of linezolid v. daptomycin for treatment of vancomycin-resistant Enterococcus bloodstream infection (VRE BSI) published in Clinical Infectious Diseases in 2015. We review what the standard of care was for treatment at this time, how this study became to be, covering this featured article and discussing outcomes/results,

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103:20

2023 NCS PharmD Research

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/13

2023 Neurocritical Care Society Annual Meeting Pharmacist-featured research 02:24 – Multicenter comparison of the safety and efficacy of clopidogrel versus ticagrelor for neuroendovascular stents featuring Casey May, PharmD, BCCCP, FNCS 15:24 – Prevalence of augmented renal clearance in neurocritical care population: a prospective multicenter study (Neuro-ARC study) featuring Sherif Mahmoud, BSc (Pharm), MSc, PhD, FNCS 24:41 – Derivation and validation of an equation to predict free valproate

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44:29

2023 Pharmacy to Dose Award Winner Celebration

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/13

2023 Pharmacy to Dose Award Winner Celebration 08:04 – Deborah Wagner, Publication of the year winner 11:35 – Megan Rech, Mentor of the year winner 13:32 – Brian Gilbert, Conference speaker of the year winner 15:45 – Melissa Thompson Bastin, Preceptor of the year winner 18:14 – Alyssa Meester and Adam Smith, Tag Team Tandem of the year winner 21:54 – Grace Erdman, PGY2 resident of the year winner 24:45 – Ruben Santiago and Andy Webb, Co-Social media star winners 28:17 – Carolyn Bell, People’s

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31:22

Trial of the Week: Phenobarbital for Acute Alcohol...

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/08

Trial of the Week: Phenobarbital for Acute Alcohol Withdrawal Special Guest: Joseph Lam, PharmD Joseph Lam joins me to highlight the 2013 trial published in the Journal of Emergency: Phenobarbital for acute alcohol withdrawal: a prospective, randomized, double-blind, placebo-controlled study. Joe shares his experience in the trial and all he did behind the scenes. Plus, we discuss the role of phenobarbital at that time, what this study found, what do we still need to know on this topic, and much

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88:40

Arrhythmias in the Emergency Department

Pharmacy to Dose: The Critical Care Podcast ·

2023/09/08

Arrhythmias in the Emergency Department Special Guests: Kyle DeWitt, PharmD, BCPS Lance Ray, PharmD, BCPS, BCEMP 05:30 – Intro/background 10:10 – Atrial arrhythmias 56:40 – EKGs/Ventricular arrhythmias 72:35 – Bradyarrhythmias/take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/09/arrhythmias-in-the-ed-references.pdf PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

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