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PODCAST

Everyday Medicine with Dr Luke

Dr Luke Crantock

Conversations with colleagues exploring their special interests in medicine and bringing to you Insights, ideas and advice for your medical practice.

health & fitness medicine

All Episodes

00:44:09

Episode 90. Venous Thromboembolism with Dr Sanjeev...

Everyday Medicine with Dr Luke ·

2022/08/30

Venous thrombosis affects more than 30,000 Australians each year and is responsible for over 5000 deaths per annum, this is more than the number of Australians who die from motor vehicle accidents annually. VTE is the third leading cause of death amongst hospitalised patients and patients admitted to hospital are at least 100 times more likely of developing a clot compared to being active in the community-a risk that may be assessed by the modified Wells criteria. Tellingly 60% of all venous

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00:33:10

Episode 89. Myasthenia Gravis and Gulian Barre...

Everyday Medicine with Dr Luke ·

2022/08/22

The Guillain Barre syndrome is an acute inflammatory demyelinating polyradiculopathy and although relatively rare (0.4-2 per 100,000) it is still the most common cause of acute flaccid neuromuscular paralysis worldwide. It famously affected Joseph Heller author of Catch-22 and more recently AFL football Legend Alexander Clarkson. It is an immune-mediated disorder that affects the peripheral nervous system and is another example of molecular mimicry, occurring 1 to 6 weeks after a respiratory

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00:54:38

Episode 88. Multiple Sclerosis with Ernest Butler

Everyday Medicine with Dr Luke ·

2022/08/14

Multiple sclerosis is an autoimmune neurodegenerative disease of the brain and spinal cord resulting in CNS demyelination affecting 2.8 million people worldwide and 23,000 Australians. There are about 1000 new cases diagnosed in Australia each year and the accumulation of disability can be devastating with an estimated 50 to 80% of patients ceasing full-time work within 10 years. The condition is 3 times more common in women and is most often seen between the ages of 20 and 40 years. The damage in

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00:34:04

Episode 87. Neuroendocrine tumours with Professor...

Everyday Medicine with Dr Luke ·

2022/08/08

Neuroendocrine tumours represent neoplasms of the diffuse neuroendocrine system (DNES) which is our body’s largest endocrine organ comprised of the fascinating amine precursor uptake and decarboxylase (APUD) cell series first described in the 1960s by British scientist A.G.E Pearse. These cells can produce numerous peptides and bioactive amines. Influenced by both the endocrine and nervous systems as well as by the chemistry in their local environment, neuroendocrine cells play a vital role in

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00:37:07

Episode 86. Neuroendocrine tumours with Professor...

Everyday Medicine with Dr Luke ·

2022/08/01

Neuroendocrine tumours represent neoplasms of the diffuse neuroendocrine system (DNES) which is our body’s largest endocrine organ comprised of the fascinating amine precursor uptake and decarboxylase (APUD) cell series first described in the 1960s by British scientist A.G.E Pearse. These cells can produce numerous peptides and bioactive amines. Influenced by both the endocrine and nervous systems as well as by the chemistry in their local environment, neuroendocrine cells play a vital role in

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00:29:33

Episode 85. Pancreatic Cancer with Dr Michael Lee

Everyday Medicine with Dr Luke ·

2022/07/25

Pancreatic cancer is the eighth most common cancer reported in Australia. In 2021, it is estimated that there will be 4261 new cases and 3391 deaths. The incidence has increased from 10 per 100,000 in 1982 -to 12 per 100,000 today with the average age of onset between 60 and 65 years. At the time of diagnosis, approximately one-third of patients already have advanced disease with a limited 3 to 4-month survival prognosis, overall, 1-year survival for pancreatic cancer is only 16% and 5-year survival

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00:40:41

Special Episode 11. Anti Virals for COVID-19 with Dr...

Everyday Medicine with Dr Luke ·

2022/07/18

As case numbers and deaths continue to climb from Covid 19 infection and its many variants, two antiviral drugs have entered the market and are now available on the Australian PBS with specific prescription criteria to be met. So, what are they and what do they do? Molnupiravir - Made by Merck in collaboration with Ridgeback Biotherapeutics was the 1st to be introduced to Australia as a trade named Lagevrio available from March 1st. This drug is a polymerase inhibitor administered as four tablets

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00:31:52

Episode 84. Lymphoma with Professor Stephen Opat...

Everyday Medicine with Dr Luke ·

2022/07/12

Lymphoma is a clonal neoplastic proliferation of lymphoid cells (B cells, T cells and NK cells) and is the sixth most common malignancy reported in this country which makes it the most common hematologic malignancy with over 5000 cases diagnosed each year in Australia putting lifetime risk at 1 in 50. There are over 70 different types of lymphoma which are divided into 2 main groups: Hodgkin's lymphoma accounts for 10% of cases and non-Hodgkin's lymphoma accounts for 90% of cases. Hodgkin's lymphoma

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00:30:47

Episode 83. Lymphoma with Professor Stephen Opat...

Everyday Medicine with Dr Luke ·

2022/07/05

Lymphoma is a clonal neoplastic proliferation of lymphoid cells (B cells, T cells and NK cells) and is the sixth most common malignancy reported in this country which makes it the most common hematologic malignancy with over 5000 cases diagnosed each year in Australia putting lifetime risk at 1 in 50. There are over 70 different types of lymphoma which are divided into 2 main groups: Hodgkin's lymphoma accounts for 10% of cases and non-Hodgkin's lymphoma accounts for 90% of cases. Hodgkin's lymphoma

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00:39:35

Special Episode 10. Monkeypox and Japanese...

Everyday Medicine with Dr Luke ·

2022/06/28

In May this year, new cases of the rare infection - Monkey Pox - typically limited to Africa, began spreading within Europe and North America. More than 780 cases have now been reported across 15 countries with Australia recently reporting 8 cases. www1.racgp.org.au - Monkeypox exposure, a member of the same family of viruses as smallpox and typically is spread through close physical contact with skin lesions, body fluids, respiratory droplets, and conta minated materials such as bedding and is much

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00:45:40

Episode 82. Advances in Anti-ageing Medicine with Dr...

Everyday Medicine with Dr Luke ·

2022/06/22

Dr John Levin practices antiaging medicine and joins this podcast to discuss his practical approach to treatment. As John laments antiaging medicine is not taught in medical school yet he believes the science of anti-ageing holds the key to significantly reducing human suffering and improving health span. Whilst the average human life span continues to increase and modern medicine more efficiently tackles diseases, the science of anti-ageing looks at mechanisms leading to cell degeneration and decay

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00:23:01

Episode 81. Polycystic ovary syndrome (PCOS) with Dr...

Everyday Medicine with Dr Luke ·

2022/06/13

PCOS is the most common endocrinopathy of reproductive age women affecting about 1 in 10. Characteristically the condition presents with menstrual irregularity, excess androgens, and polycystic ovarian morphology. More common in women with a family history and type 2 diabetes the condition is associated with obesity, infertility, pregnancy complications and metabolic derangements as well as a number of psychological consequences. In this podcast we have a conversation with obstetrician and

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00:29:24

Episode 80. Endometriosis with Dr Mei Cheah

Everyday Medicine with Dr Luke ·

2022/06/06

Endometriosis is the presence of endometrial tissue outside the uterus or embedded within its muscular wall. This unusual condition is known to induce a chronic inflammatory reaction that may be associated with pelvic pain and infertility. In women of reproductive age the estimated prevalence is 7 to 10% and up to one third of women undergoing laparoscopy for pelvic pain are diagnosed with endometriosis. Endometrial deposits may be deeply infiltrating, found in the abdomen and pelvic region may be

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00:19:53

Episode 79. Investigations in Rheumatology with Dr...

Everyday Medicine with Dr Luke ·

2022/05/31

In this episode we explore investigations in rheumatology-what is helpful and what is not? A clinician faced with a patient complaining of myalgias and generalised rheumatic aches may be tempted to order a host of immunological and inflammatory tests whilst also assessing multiple other differential diagnoses that need considering. There are a host of serological tests available each with different degrees of sensitivity and specificity for rheumatological conditions, furthermore it is important to

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00:40:29

Episode 78. New Agents in Rheumatology with Dr Andrew...

Everyday Medicine with Dr Luke ·

2022/05/24

The past two decades have witnessed dramatic changes in the approach to managing rheumatologic conditions, born of a wider understanding of cellular biology, immunology, and the pathophysiology of inflammation we have consequently seen an explosion in the development and availability of both Biologic medications and small molecules for medical applications. Some of these products are designed to interfere with cytokine function or production and include: · TNF inhibitors · TNF receptor fusion

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00:45:32

Episode 77. The Microbiome with Dr Mark Morrison

Everyday Medicine with Dr Luke ·

2022/05/16

Trillions of microbes are living in and on us, a thriving ecosystem of bacteria, viruses, archaea and fungi. Collectively these microbes form the human microbiome and this microbiome appears to play a key role in many aspects of health, crowding out harmful microbial invaders, breaking down fibrous food into digestible compounds and producing some essential vitamins such as B12 and vitamin K. New research is exploring the relationship between the gut microbiome and immunogenicity, autoimmune

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00:45:29

Episode 76. Breast Cancer with Dr Corinne Ooi

Everyday Medicine with Dr Luke ·

2022/05/09

Breast cancer affects 1 in 7 women and remains the most diagnosed cancer in Australia with 57 new cases diagnosed each day, 1000 new cases per year and tragically 2000 deaths annually. Men are not excluded, for every 100 breast cancers one is diagnosed in a male. Genetic links for breast cancer such as the BRCA 1 and 2 genes receive significant attention but account for only 5% of total cases,75% of patients have no family history and additionally 75% of breast cancers are diagnosed in patients 50

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00:34:04

Episode 75. Urinary Incontintence in Women with Dr...

Everyday Medicine with Dr Luke ·

2022/05/03

Dr Natharnia Young is a leading urogynaecologist servicing South Eastern Melbourne’s suburbs and joins this conversation to discuss urinary incontinence in women, a condition associated with significant personal and social stigmatisation and affecting up to 1:2 women over the age of 70. Rates of presentation by woman seeking management for stress incontinence and urge incontinence are low, perhaps on account of feelings of embarrassment and shame however there are many effective management

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00:23:06

Episode 74. Sports Medicine and Supplements with Dr...

Everyday Medicine with Dr Luke ·

2022/04/25

Dr Peter Brukner OAM is Professor of Sports Medicine at the Latrobe Sport and Exercise Medicine Research Centre and is one of Australia’s most respected and best-known specialist sports physicians with a wide breadth of knowledge of the subject. He has extensive experience, having enjoyed a stellar career with elite sports teams and Olympians over multiple decades in his professional capacity. In this episode we discuss, several questions related to commonly used supplements taken by amateur and

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00:32:57

Episode 73. Sports Medicine and Low Carbohydrate Diet...

Everyday Medicine with Dr Luke ·

2022/04/19

Dr Peter Brukner OAM is Professor of Sports Medicine at the Latrobe Sport and Exercise Medicine Research Centre at Latrobe University and is one of Australia’s most respected and best known specialist sports physicians. He has a deep breadth of knowledge and experience and was a founding partner at the Olympic Sports Medicine Centre in Melbourne as well as a sports physician to the Collingwood and Melbourne AFL clubs, Liverpool Football Club and has served as team doctor to the Australian cricket

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