NEJM This Week

Featuring articles on a drug-eluting scaffold for infrapopliteal disease, a phase 2 trial of sibeprenlimab in IgA nephropathy, liquefied petroleum gas cooking and the effects on severe infant pneumonia and on stunting in infants; a review article on communicating about serious illness and end of life; a Clinical Problem-Solving describing a swell diagnosis; and Perspective articles on the Journal’s historical “Indian Problem”.

Featuring articles on dual or single antiplatelet treatment up to 72 hours after stroke, nirsevimab for prevention of RSV hospitalization in infants, sparsentan in focal segmental glomerulosclerosis, transfusion strategy in patients with myocardial infarction and anemia, and the effect of alcohol reduction on cancer incidence; a review article on wearable technology in clinical practice for depressive disorder; a case report of a woman with cough and shortness of breath; and Perspective articles on

Featuring articles on percutaneous coronary intervention for stable angina, doxycycline prophylaxis to prevent STIs in women, simvastatin for critically ill patients with Covid-19, and melioidosis in Mississippi; a review article on eye infections; a case report of a woman with chronic diarrhea and skin changes; and Perspective articles on when patients lose decision-making capacity, on silencing the FDA’s voice, and on being hidden behind bars.

Featuring articles on semaglutide for prevention of cardiovascular events, an mRNA-based RSV PreF vaccine in older adults, recombinant or standard-dose influenza vaccine, tebentafusp in metastatic uveal melanoma, and on the predominance of Medicare Advantage; a review article on cannabis-related disorders and toxic effects; a case report of a woman with abnormal movements and confusion; and Perspective articles on medicine’s lessons for AI regulation, on “unwinding” continuous Medicaid coverage, and