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PODCAST

Listen In - Bitesize Bio Webinar Audios

The Listen In podcast from Bitesize Bio is a compilation of our best webinars to enjoy at your leisure, wherever and whenever. Each episode is an opportunity to gain the valuable insights you need to advance your research. From a crash course in developing fool-proof ELISAs to the latest applications and innovations in CRISPR/Cas9 and microscopy techniques, and much more—you"ll hear about challenges encountered and discover practical solutions to achieve the best possible results. Tap into the

science life sciences

All Episodes

62:00

Mouse Whole-Brain Cellular Connectomics

Listen In - Bitesize Bio Webinar Audios ·

2022/09/01

Recent advances in high-throughput multi-beam scanning electron microscopy (EM) and mouse whole-brain EM preparation and collection on tape (“Brain-on-Tape”) have resulted in substantial progress towards a nano-scale map of the whole mouse brain. These maps can be used to determine how individual neurons are synaptically connected and can be used to reconstruct the precise “wiring diagram” of the whole mouse brain. We discuss the methods, recent results and remaining challenges. The ZEISS

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48:59

Engineering Cell Behaviour with Synthetic Biology

Listen In - Bitesize Bio Webinar Audios ·

2022/09/01

In this webinar, you will learn how synthetic biology can be used to engineer desirable and robust behaviors or traits into model organisms.The main aspects to be covered in this webinar include:Introduction to synthetic biology – what it is and what it’s notPopular applications for synthetic biology in researchThe pros and cons of synthetic biologyTips and resources for getting started in this fieldThe Sky Is the Limit with Synthetic Biology!The notion of synthetic biology began to receive

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53:19

Develop A Potential Recombinant Protein Vaccine in...

Listen In - Bitesize Bio Webinar Audios ·

2022/09/01

Expression and Purification of an Engineered, E. coli-expressed Leishmania donovani Nucleoside Hydrolase with Immunogenic PropertiesPotential recombinant protein vaccine candidates must meet several criteria:They must be expressed at sufficiently high levels in the organism of choiceThey must be purified to high purity from the expression system in an immunogenic formThey must induce potent immune responsesDr. Patrick McAtee will take you through these vaccine development steps using the

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61:25

Guide to CRISPR/Cas9 Delivery How to Maximize Editing

Listen In - Bitesize Bio Webinar Audios ·

2022/09/01

In this webinar, you will learn how to maximize your genome editing efficiency using CRISPR/Cas9 and how to apply this technique in your research.The main points in the webinar will include:How to design guide RNAs using online tools specific to the genome and application of interest.Tips and practical advice to assist you in choosing and optimizing a CRISPR/Cas9 delivery system.How you can create precise mutations using homology-directed repair, including template design and cleavage

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58:51

Multiplex PCR Technology: What Is It All About?

Listen In - Bitesize Bio Webinar Audios ·

2022/09/01

Join Dr. Karen O’Hanlon Cohrt for a practical tour of multiplex PCR technology, where you will learn the following and much more:Principle behind multiplex PCR technologyPopular applications of this technologyHow to set up this reactionAdvantages and disadvantagesMultiplex PCR Can Benefit Your ResearchDr O’Hanlon Cohrt will discuss the history of multiplex PCR, how the technique works, and how to set up a reaction. She will also provide advice for optimization of primers and how to detect

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66:19

Open Access Facts Myths & Effects on Your Research Fund

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

The rise of open access is changing how research is communicated. In this webinar, we’ll celebrate Open Access Week 2016 by taking a closer look at how open access affects how researchers write and publish their results. Specifically, we will:Define open access and Creative Commons licensing and dive into the numbers about open access (journals, articles, fees)Discuss the pros and cons of open access and dispel some mythsDescribe how funder and government mandates will affect the open

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52:31

Color Image Quality Control in Microscopy

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

In this webinar, you will learn about color reproduction in microscopy images—and how to fix it if your color reproduction goes awry.The main points we will cover are:The reasons that could color reproduction go wrong in your microscopy imagesHow to correct your microscopy images with inappropriate color reproductionHow to be ethical with the color in your microscopy imagesAdvice on Color in Microscopy ImagesMark Clymer, an expert in microscopy imaging, will guide you through the

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41:55

Incorporating New Dyes to Simplify Panel Design/Reagent

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Incorporating New Dyes to Simplify Panel Design: Accelerating Reagent AvailabilityIn this webinar you will learn how custom reagents can aid you in flow cytometry panel design—without long waits for generating these components.We will cover:How quality custom reagents in small sizes will make your panel design easierHow you can receive these reagents fast and without traditional wait times for manufacturingHow you can be confident that quality control is maintained for these custom

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61:59

Decoding Cancer: Practical Advice for Working with...

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

In this webinar, you will learn about the process for genotyping cells—particularly tumor cells—and practical advice for analyzing the resulting data.The main points that we will cover are:Practical advice and methods for sample collection and preparation for your genotyping experimentsAn overview of the available data analysis methods for your genotyping resultsExamples of pathway analysis methods for determining potential mechanisms within your systemAdvice, tips, and applications for

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76:46

All About miRNAs Practical Tips Advice and Applications

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

In this webinar you will learn the tips and tricks necessary for you to successfully work with miRNAs, and how you can use them to further your research. The main points we will cover are: Tips and practical advice to help you work with miRNAs, including isolation and delivery The biology and mechanism of miRNAs and why this matters to your research An example of how miRNAs are being used in disease research. The presenter will take you through the identification of certain aberrantly

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61:59

Tools for Analyzing Genetic Variants from Sequencing...

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Tools for Analyzing Genetic Variants froEvery individual harbors millions of genetic variants, many of which may contribute to phenotype. As the cost of sequencing has plummeted, we now have the opportunity to profile this variation across thousands of individuals. Here I will provide an overview of the workflow to analyze various types of genetic variation, starting from raw sequencing data and ending with high quality genotypes. I will first present state of the art methods for mapping

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50:43

Actionable Steps to Transition to a Non-faculty Career

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

The current state of the academic job market has come under scrutiny in recent years, largely because of the shrinking number of tenure-track jobs available. This situation has forced graduate students and postdocs to reconsider their employment options. Other scholars may realize that academia is no longer a good fit for them but are unsure of how to land a non-faculty position. This process of self-reflection and job searching can be filled with anxiety and fear. But it doesn’t have to

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68:14

Next-Generation Sequencing Overview: Step By Step Guide

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Next generation sequencing (NGS) is a powerful tool for investigating genome-wide phenomena. It has been used to study epigenetic profiles as part of the ENCODE project. It is being used to understand the genetic basis of both common and rare diseases. The Cancer Genome Atlas (TCGA) used NGS to map hundreds of cancer genes. There is no area of modern genetic research that has not been transformed by the advent of NGS. With continued improvements of throughput and yield, the number of human

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43:09

How Bitesize Bio Gets Progressive Companies to Help You

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Whether it’s equipment costing hundreds of thousands of dollars and requiring millions of dollars in R&D investments or standardized kits that relieve you of tedious grunt work day in and day out, you rely on the support of companies like our sponsors to provide you with the equipment and supplies you need. But beyond the things they sell, these companies know a thing or two about your work-a-day world. In this webinar we will discuss how we get them to “give it up” and freely share the

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54:23

Using FIT probes and Super-Resolution Microscopy

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

All mRNA molecules recruit specific proteins to form ribonucleoprotein complexes (mRNPs). Composition and localization of many mRNPs change dynamically from translation to decay. Microscopic techniques with high spatial and temporal resolution are invaluable for studying mRNP biogenesis.We have developed new tools based on fluorogenic forced intercalation (FIT) probes for RNA detection, quantification and interference in biological samples. The probes contain a thiazole orange (TO) dye

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65:15

Know the Players: Combinatorial, Single-Cell Approaches

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

We know that cellular heterogeneity in the tumor microenvironment complicates the diagnosis and treatment of cancer. Tumors are complex, dynamic systems composed of diverse cell types in various functional states, including cancer cells and infiltrating immune cells. Resolving this cellular heterogeneity requires a single-cell approach, as analyses on bulk cell preparations mask the heterogeneity of the biological system and may lead researchers down the wrong path.Cutting-edge single-cell

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44:37

Critical Success Factors for Sample Collection

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Biobanks, or biorepositories, store biological samples that are critical for research in the biomedical fields. Samples from biobanks have been used for genomics research, investigations into the development of personalized medicine, and treatment of diseases.After obtaining precious specimens, it is important to not only store them for easy retrieval, but is also vital to treat the samples so there are no complications for downstream uses. Tissues, blood, and cells all have unique

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72:54

Laser Microdissection – Dissection Perfection

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Leica Microsystems Laser Microdissection systems are the method of choice for laser-based microscopic sample dissection and collection. Laser Microdissection (LMD) is a microscopic technique for isolating homogeneous, specific and pure targets from heterogeneous samples for downstream analysis (DNA, RNA & proteins). In addition, the Leica Microsystems LMD systems can be used with live cell cultures (LCC, e.g. cloning) and as a manipulation tool (e.g. for live cell/organism manipulation,

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69:09

How To Be Happier and More Productive in Your Work

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Enjoying your work should be one of life’s top priorities not only because you spend much of your time working, but also because if you enjoy your work you’ll inevitably do a better job.Having worked in an uptight academic lab, a very laid-back Danish biotech company, a typically British biotech lab and been my own working-from-home boss for a number of years I have tried many different approaches and structures for my day, work and life.Although it is still a work in progress, the result

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46:10

Getting Correct Color from Your Camera

Listen In - Bitesize Bio Webinar Audios ·

2022/08/31

Seeing and believing that the dress is yellow may not be that important for the casual wedding image, but in microscopy imaging seeing and believing is critical. Microscopy images that contain color, such as images from histology-stained specimens, must be compared and analyzed. If the color reproduction is poor, then there’s a chance that important information will be overlooked, not seen, and not believed.For more information visit:

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