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PODCAST

Smart Biotech Scientist | Master Bioprocess CMC Development, Biologics Manufacturing & Scale-up, Cell Culture Innovation

David Brühlmann - CMC Development Leader, Biotech C-level Advisor, Business Strategist

The Go-to Podcast for Biotech Scientists Who Want to Master Biopharma CMC Development and Biomanufacturing.**TOP 10 LIFE SCIENCES PODCAST**Are you ready to simplify bioprocess development and scale with confidence to reduce time to market?Are you feeling overwhelmed by the complexity and guesswork of biologics development and biomanufacturing?Do you wish you had more time to enjoy the beauty of science, without worrying about failing your cell culture process development and

science life sciences

All Episodes

19:53

96: AI in Bioprocess Development: The Game-Changer...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/10/10

Send us a textAre you ready to revolutionize your bioprocess development? Join David Brühlmann as he interviews Belma Alispahic, Chief Scientific Officer and Co-Founder of AnalysisMode, who unveils the game-changing potential of AI in biopharma.Discover how AI is transforming the industry, from drug discovery to manufacturing, and learn why it's no longer optional but essential for success.Key takeaways:Leverage AI to streamline experiments, reduce costs, and accelerate your path to marketGai...

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20:37

95: AI in Bioprocess Development: The Game-Changer...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/10/08

Send us a textIs AI the secret weapon biotech scientists have been waiting for? In this eye-opening episode, we dive deep into the world of AI-driven bioprocess development with Belma Alispahic, Chief Scientific Officer and Co-Founder of AnalysisMode. Discover how AI is transforming the biotech landscape, from reducing downtime by 50% to unlocking unprecedented levels of precision in process optimization.Key takeaways:Learn how AI can slash experiment time by up to 80%, saving you valuable re...

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19:31

94: From Lab Coat to LinkedIn: Benjamin McLeod's...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/10/03

Send us a textIn this electrifying episode, we dive deep into the future of biotech with biotech influencer Benjamin McLeod. From quantum AI mapping cellular interactions to the game-changing potential of process analytical technology, Ben, who is also a Cell & Gene Therapy Segment Lead at NanoMosaic, unveils how artificial intelligence is set to transform the cell and gene therapy landscape.Discover why LinkedIn is becoming the new frontier for biotech networking and career advancement. ...

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24:04

93: From Lab Coat to LinkedIn: Benjamin McLeod's...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/10/01

Send us a textDiscover how a failed optometry dream led Benjamin McLeod to become a leading voice in cell and gene therapy. In this eye-opening episode, Ben, who is a Cell & Gene Therapy Segment Lead at NanoMosaic, shares his unconventional path from lab work to LinkedIn stardom, revealing how he bridges the gap between R&D and marketing in biotech.Learn how Ben's weekly science memes evolved into valuable content that attracts both lab techs and CEOs alike.Key takeaways:Gain insider ...

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16:29

92: Mass Transfer Secrets: Mastering Bubbles and kLa...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/26

Send us a textEver wondered why your perfectly optimized lab process falls apart at industrial scale?Mass transfer experts Lars Puiman and Rik Volger from the University of Delft reveal the hidden world of oxygen transfer and aeration that can make or break your production.Dive into the crucial differences between lab-scale and industrial-scale bioreactors, and discover why your DO sensor might be fooling you. Learn how CFD simulations and innovative downscaling techniques can revolutionize y...

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16:37

91: Mass Transfer Secrets: Mastering Bubbles and kLa...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/24

Send us a textUnlock the mysteries of oxygen transfer in bioreactors with mass transfer experts Lars Puiman and Rik Volger from the University of Delft. In this eye-opening episode, dive deep into the crucial world of kLa (oxygen mass transfer coefficient) and its impact on bioprocess scale-up.Discover why understanding kLa is essential for optimizing cell growth and product formation in bioreactors. Learn practical strategies to enhance oxygen transfer, from manipulating bubble size to lever...

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25:14

90: Scale-Up Secrets: Cracking the Code of AAV...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/19

Send us a textDive into the cutting-edge world of gene therapy as we unravel the complexities of AAV production. In this insightful episode, Ahmed Youssef, a seasoned AAV expert and Senior Process Development Manager at Ascend, explains how you can navigate the complex world of AAV scale-up and learn why thinking outside the box is crucial for success.Key takeaways:Leverage early expert advice to ensure your therapeutic's long-term viabilityExplore innovative technologies like doggy bone DNA ...

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20:08

89: Scale-Up Secrets: Cracking the Code of AAV...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/17

Send us a textUnlock the mysteries of AAV manufacturing in this eye-opening episode! Ahmed, a seasoned AAV expert and Senior Process Development Manager at Ascend, reveals insider strategies for biotech scientists navigating the complex world of gene therapy production.Discover why quality is the cornerstone of successful AAV development and how to avoid costly missteps in the journey from lab to clinic.Key takeaways:Learn to design a robust AAV manufacturing process that stands up to regulat...

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16:38

88: The Swiss Army Knife of Biotech: Unleashing the...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/12

Send us a textUnlock the secret weapon of biotech success! In this eye-opening episode, host David Brühlmann reveals how fractional CTOs are revolutionizing drug development, inspired by Michael Jordan's approach to greatness. Learn how this innovative strategy can slash timelines, mitigate risks, and give your biotech company a competitive edge.Discover the game-changing benefits of fractional expertise:Gain rapid access to broad biotech knowledge, navigating complex challenges with ease.Sla...

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16:54

87: The Hidden Pitfalls of Bioprocess Development:...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/10

Send us a textUnlock the secrets of successful bioprocess development with host David Brühlmann as he shares hard-won lessons from his 15+ years of experience leading technology transfers and technology innovation projects.Discover why prioritizing process development is crucial for transforming groundbreaking science into life-changing therapies. In this eye-opening episode, you'll learn:How to avoid costly mistakes in technology transfer and scale-up, saving you time and resourcesStrategies...

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23:01

86: Bioprocess 4.0: Integrated Continuous...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/05

Send us a textWhat if your biomanufacturing facility could run itself, optimize its own processes, and operate non-stop? This isn't science fiction – it's the cutting-edge reality Professor Massimo Morbidelli is helping to create.In this captivating episode, the bioprocessing pioneer unveils how AI, continuous manufacturing, and revolutionary machine learning techniques are transforming the industry landscape.As a Professor Emeritus at ETH Zurich and Politecnico di Milano, and a co-founder of...

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24:04

85: Bioprocess 4.0: Integrated Continuous...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/09/03

Send us a textImagine a world where biologic drugs are produced faster, cheaper, and with unprecedented precision.In this episode, we dive into that future with Professor Massimo Morbidelli, a trailblazer in bioprocessing innovation. As a Professor Emeritus at ETH Zurich and Politecnico di Milano, and a co-founder of ChromaCon (now YMC) and DataHow, Massimo Morbidelli has been at the forefront of bioprocess innovation. He is currently the recipient of the ERC Advanced Grant Continuous Digital...

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23:17

84: The Hidden Potential of Shake Flasks: What Every...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/29

Send us a textAre your shake flasks holding back your bioprocess development? Discover how to transform them into smart bioreactors! In this game-changing episode, we talk with Jens Bayer about the groundbreaking DOTS platform. He is a deep tech entrepreneur and seasoned commercial leader, currently serving as Chief Commercial Officer at Scientific Bioprocessing.Jens reveals how this cutting-edge technology is bridging the gap between simple shake flasks and complex bioreactors, offering scie...

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18:25

83: The Hidden Potential of Shake Flasks: What Every...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/27

Send us a Text Message.Are shake flasks outdated relics or untapped goldmines of bioprocess development? In this eye-opening episode, we dive deep with Jens Bayer, a deep tech entrepreneur and seasoned commercial leader, currently serving as Chief Commercial Officer at Scientific Bioprocessing.Jens shatters common misconceptions about shake flasks, revealing why they remain indispensable tools in both industry and research settings.Discover:Why shake flasks are irreplaceable for rapid, cost-e...

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17:58

82: Regenerating Muscles: The Future of Autologous...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/22

Send us a Text Message.Dive into the cutting-edge world of autologous cell-based therapy with Deana Mohr, CEO and co-founder of MUVON Therapeutics, spin-off from the University of Zurich. In this eye-opening episode, discover how MUVON Therapeutics’ innovative approach to muscle regeneration is revolutionizing treatments for stress urinary incontinence and beyond.Learn how her team is tackling the challenges of bringing personalized medicine to market at scale, from navigating complex regulat...

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22:35

81: Regenerating Muscles: The Future of Autologous...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/20

Send us a Text Message.Discover how scientists are transforming lives through innovative muscle regeneration therapy. In this captivating episode, Deana Mohr, CEO and co-founder of MUVON Therapeutics, spin-off from the University of Zurich, unveils her groundbreaking autologous muscle regeneration technology for treating stress urinary incontinence.Learn how this minimally invasive treatment harnesses the power of a patient's own cells to restore muscle function, offering hope to millions. Di...

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20:14

80: Think Before You Build: Holistic Approaches to...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/15

Send us a Text Message.Ever wondered why some biotech facilities thrive while others struggle Alfredo Martínez Mogarra, a Bioprocess Engineer with over 30 years of experience and Chief Operations Manager at VIVEbiotech, reveals the secrets to successful biotech manufacturing.In this eye-opening episode, Alfredo shares critical insights on bridging the gap between lab-scale processes and industrial production.You will get:Strategies for seamless scale-up and risk mitigation in bioprocess devel...

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24:24

79: Think Before You Build: Holistic Approaches to...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/13

Send us a Text Message.Ever wondered what it takes to build a large-scale biotech manufacturing facility? Alfredo Martínez Mogarra, a seasoned Bioprocess Engineer with over 30 years of experience and Chief Operations Manager at VIVEbiotech, reveals the secrets behind successful biotech facility design and scale-up. He has been at the forefront of transforming bench processes into industrial realities.In this eye-opening episode, Alfredo shares critical insights on navigating the complex world...

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18:10

78: Cell Factories Explained: How Synthetic Biology...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/08

Send us a Text Message.Unlock the secrets of cell factories and discover how cutting-edge technologies are revolutionizing biopharmaceutical production. In this episode, we welcome Mauro Torres, a postdoctoral researcher at the University of Manchester, who takes us on a fascinating journey through the complex world of protein manufacturing.Mauro Torres explains the intricate steps involved in the secretory pathway, from gene expression to protein export, likening it to a sophisticated car ma...

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23:00

77: Cell Factories Explained: How Synthetic Biology...

Smart Biotech Scientist | Master Bioprocess CMC... ·

2024/08/06

Send us a Text Message.Unlock the secrets of cell factories with Mauro Torres, a postdoctoral researcher at the University of Manchester who brings cutting-edge insights into protein production. Discover how the concept of cell factories has evolved from basic insulin extraction to groundbreaking treatments for genetic disorders and cancer. We reveal the challenges faced by biotech scientists in bioprocess development and offers a fascinating analogy between car manufacturing and cellular pro...

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184 results

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