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PODCAST

No Priors: Artificial Intelligence | Technology | Startups

At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world"s leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com. Sarah Guo is a startup investor and the founder of Conviction, an investment firm

technology entrepreneurship

All Episodes

43:07

From App to Suite to Platform, with HubSpot's...

No Priors: Artificial Intelligence | Technology |... ·

2023/10/12

Startups aren't the only companies racing to build the new world of AI. This week, Sarah Guo talks with Brian Halligan, the co-founder, longtime CEO and now executive chairperson of HubSpot, the fastest growing CRM. He talks about category creation, coining the term ‘inbound marketing,’ lessons in scaling from an app to a suite to a platform, staying innovative at scale, and how they're navigating the AI disruption. Brian also describes the life-threatening moment he decided to step back from the

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23:53

Model Quality, Fine Tuning & Meta Sponsoring Open...

No Priors: Artificial Intelligence | Technology |... ·

2023/10/09

What Does it Take to Improve by 10x or 100x? This week is another host-only episode. Sarah and Elad talk about the path to better model quality, the potential for fine tuning to different use cases, retrieval systems (RAG), feedback systems (RLHF, RLAIF) and Meta’s sponsorship of the open source model ecosystem. Plus Sarah and Elad ask if we’re finally at the beginning of a new set of consumer applications and social networks. Sign up for new podcasts every week. Email feedback to

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37:00

If DNA is Code, Can AI Help Write It? Scaling Cell...

No Priors: Artificial Intelligence | Technology |... ·

2023/09/28

Ginkgo Bioworks is using DNA as code to digitize the cell programming revolution. Ginkgo is using AI and synthetic biology to keep the next pandemic at bay, and accelerate our production capabilities for medicine, food, and agriculture. Ginkgo’s co-founder and CEO Jason Kelly joins hosts Sarah Guo and Elad Gil to discuss bioengineering protein as a foundational model, specialized data learning from an evolutionary perspective, what we need to prepare for a future pandemic, and more. Jason has

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29:37

How Replit’s AI Tools are Changing Software...

No Priors: Artificial Intelligence | Technology |... ·

2023/09/21

Replit’s develop-to-deploy platform and new AI tool, Ghostwriter, are breaking down the barriers to entry for beginner programmers. Replit’s CEO, co-founder, and head engineer Amjad Masad joins hosts Sarah Guo and Elad Gil to discuss how AI can change software engineering, the infrastructure we still need, open source foundation models, and what to expect from AI agents. Before co-founding Replit, Amjad Masad worked at Facebook as a software engineer, where he worked on infrastructure tooling. He

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42:24

The Intersection of AI and Blockchain, with...

No Priors: Artificial Intelligence | Technology |... ·

2023/09/15

More than 25 million users are using NEAR-powered applications. Co-founder of NEAR protocol and Transformers author Illia Polosukhin joins hosts Sarah Guo and Elad Gil to discuss the intersections of crypto and AI technology, what we should expect from AI agents, decentralized data labeling, why AI’s alignment problem is really a human problem, and more. Show Links: Illia Polosukhin - Co-founder of NEAR | LinkedIn NEAR Sign up for new podcasts every week. Email feedback

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30:03

The World’s Largest AI Processor with Cerebras CEO...

No Priors: Artificial Intelligence | Technology |... ·

2023/09/07

The GPU supply crunch is causing desperation amongst AI teams large and small. Cerebras Systems has an answer, and it’s a chip the size of a dinner plate. Andrew Feldman, CEO and Co-founder of Cerebras and previously SeaMicro, joins Sarah Guo and Elad Gil this week on No Priors. They discuss why there might be an alternative to Nvidia, localized models and predictions for the accelerator market. Show Links: Andrew Feldman - Cerebras CEO & Co-founder | LinkedIn Cerebras Sign up for new

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38:13

AI Superpowers for Frontend Developers, with Vercel...

No Priors: Artificial Intelligence | Technology |... ·

2023/08/31

Everything digital is increasingly intermediated through web user experiences, and now AI development can be frontend-first, too. Just ask Guillermo Rauch, the founder and CEO of Vercel, the company behind Next.js. In this episode of No Priors, hosts Sarah Guo and Elad Gil speak to Guillermo about their AI SDK and AI templates, and why Vercel is focused on making it easy for every frontend engineer to build with AI. They also discuss what applications Guillermo's most excited about, how to prepare

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35:23

AI-Powered Biological Software with Jakob Uszkoreit,...

No Priors: Artificial Intelligence | Technology |... ·

2023/08/24

"Biological Software" is the future of medicine. Jakob Uszkoreit, CEO and Co-founder of Inceptive, joins Sarah Guo and Elad Gil this week on No Priors, to discuss how deep learning is expanding the horizons of RNA and mRNA therapeutics. Jakob co-authored the revolutionary paper Attention is All You Need while at Google, and led early Google Translate and Google Assistant teams. Now at Inceptive, he's applying these same architectures and ideas to biological design, optimizing vaccine production, and

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47:42

The AI Tutor For Every Child and the Next Frontier of...

No Priors: Artificial Intelligence | Technology |... ·

2023/08/17

The future of education is right at your children’s fingertips. Sal Khan, CEO and Founder of Khan Academy, joins Sarah Guo and Elad Gil this week on No Priors. For over a decade, Sal Khan has been trying to reform education, beginning with tutoring his cousins in math. He's the father of the YouTube "chalk talk" format, and has now served tens of millions of students through Khan Academy. He guides us through how Khan Academy is using AI to personalize a student's educational experience,

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24:01

Listener Q&A: 2024 Tech Market Predictions, Long Term...

No Priors: Artificial Intelligence | Technology |... ·

2023/08/10

This week on the podcast, Sarah Guo and Elad Gil answer listener questions on the state of technology and artificial intelligence. Sarah and Elad also talk about the 2024 tech market, what type of companies may reach their highest valuation ever and the (former) unicorns that may go bust. Plus, how do Sarah and Elad define happiness? Hint: it’s a use case for a specialized AI agent. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on

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43:44

Eradicating Machine Learning Pain Points with Weights...

No Priors: Artificial Intelligence | Technology |... ·

2023/08/03

How are ML developer tools helping to advance our capabilities? Lukas Biewald, CEO of Weights & Biases, joins Sarah Guo and Elad Gil this week on No Priors. Lukas explores the impact of ML in various industries like gaming, AgTech, and fintech through his insightful perspective. He discusses the impact of LLMs, puts them in context of the evolution of ML engineering over the past decade and a half, and tells the backstory of Weights & Biases' success. He gives advice for aspiring AI company

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39:45

How Palantir’s AI Bet is Revolutionizing Defense and...

No Priors: Artificial Intelligence | Technology |... ·

2023/07/27

Can frontiers as high-stakes as next-generation, AI-enabled defense depend on something as mundane as data integration? Can "large language models" work in such mission critical applications? In this episode of No Priors, hosts Sarah Guo and Elad Gil are joined by Shyam Sankar, the Chief Technical Officer of Palantir Technologies and inventor of their famous Forward Deployed Engineering force. Early employee and longtime leader Shyam explains the evolution of technology at Palantir, from ontology

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39:50

The Timeline for Realistic 4-D: Devi Parikh from Meta...

No Priors: Artificial Intelligence | Technology |... ·

2023/07/20

Video dominates modern media consumption, but video creation is still expensive and difficult. AI-generated and edited video is a holy grail of democratized creative expression. This week on No Priors, Sarah Guo and Elad Gil sit down with Devi Parikh. She is a Research Director in Generative AI at Meta and an Associate Professor in the School of Interactive Computing at Georgia Tech. Her work focuses on multimodality and AI for images, audio and video. Recently, she worked on Make a Video 3D, also

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51:52

Bringing AI to the Data Cloud, with Snowflake's CEO...

No Priors: Artificial Intelligence | Technology |... ·

2023/06/29

Frank Slootman, CEO of Snowflake Computing, joins Sarah Guo and Elad Gil this week on No Priors. Before scaling Snowflake to its blockbuster IPO and beyond, Frank was also the CEO from early to scale for landmark enterprise companies ServiceNow and Data Domain. Frank grew up in the Netherlands and is also the author of three books: Amp It Up, Rise of the Data Cloud, and Tape Sucks. In this episode, our hosts talk with Frank about the opportunity for generative AI in the enterprise, why Snowflake

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40:07

What's for Dinner? AI-Driven Commerce with Instacart...

No Priors: Artificial Intelligence | Technology |... ·

2023/06/22

Fidji Simo, the CEO of Instacart and co-founder of Metrodora Institute, a medical center and research institute for neuroimmune axis disorders, shares her personal journey from growing up in France, to leading the Facebook app, to becoming a wartime CEO. Fidji talks about the future of Instacart, their AI strategy, how the current era of AI is different from prior ML waves, and the impact of LLMs in commerce, robotics and healthcare. She also shares how she earns followership from her teams. ** No

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44:48

What happens to Observability If Code is...

No Priors: Artificial Intelligence | Technology |... ·

2023/06/15

Olivier Pomel, co-founder and CEO of Datadog, the leading observability company, discusses the company’s founding story, early product sequencing, platform strategy, and acquisitions. Olivier also shares his thoughts on their more recent expansion into security, and why he’s bullish on the potential for AI in DevOps. ** No Priors is taking a summer break! The podcast will be back with new episodes in three weeks. Join us on July 20th for a conversation with Devi Parikh, Research Director in

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35:27

Listener Q&A: AI Misconceptions, The Reality of...

No Priors: Artificial Intelligence | Technology |... ·

2023/06/08

This week on No Priors, Sarah and Elad do another hangout to answer listener questions. Topics include debunking common misconceptions about AI and its implications on the world, the analogy to nuclear power and nuclear safety, the impact of larger context windows, developer productivity, incumbent announcements of AI products, and some requests for (fat) startups. No Priors is now on YouTube! Subscribe to the channel on YouTube and like this episode. Sign up for new podcasts every week. Email

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50:36

AI & Defense Technology with Anduril CEO Brian Schimpf

No Priors: Artificial Intelligence | Technology |... ·

2023/06/01

Today on No Priors, we discuss defense technology, AI, drones, and autonomous vehicles (think giant submarine drones!) with Brian Schimpf, the co-founder and CEO of Anduril, a next-generation defense technology company. From his early days of coding at age 12 to working on self-driving cars, and finally founding Anduril, Brian's incredible journey led him to create innovative solutions for pressing defense problems. This episode covers the impact of AI, intelligent software, and other technologies

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55:26

Going Full Send on AI, and the (Positive) Impact of...

No Priors: Artificial Intelligence | Technology |... ·

2023/05/24

In this episode, Sarah and Elad speak with Microsoft CTO Kevin Scott about his unlikely journey from rural Virginia to becoming the driving force behind Microsoft's AI strategy. Sarah and Elad discuss the partnership that Kevin helped forge between Microsoft and OpenAI and explore the vision both companies have for the future of AI. They also discuss yesterday’s announcement of “copilots” across the Microsoft product suite, Microsoft’s GPU computing budget, the potential impact of open source AI

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42:48

The AI Will See You Now: Exploring Biomedical AI and...

No Priors: Artificial Intelligence | Technology |... ·

2023/05/18

What if AI could revolutionize healthcare with advanced language learning models? Sarah and Elad welcome Karan Singhal, Staff Software Engineer at Google Research, who specializes in medical AI and the development of MedPaLM2. On this episode, Karan emphasizes the importance of safety in medical AI applications and how language models like MedPaLM2 have the potential to augment scientific workflows and transform the standard of care. Other topics include the best workflows for AI integration, the

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157 results

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