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PODCAST

This Week in Microbiology

Vincent Racaniello

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows "This Week in Virology" (TWiV) and "This Week in Parasitism" (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

science life sciences

All Episodes

01:15:03

224: One hundred million year old bacteria

This Week in Microbiology ·

2020/08/28

The TWiM team reveals the genetic mysteries of the Dead Sea Scrolls from sequencing of DNA, and 100 million year old living bacteria recovered from marine sediments. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Become a patron of TWiM. Links for this episode: Elio’s Memoirs Genetic mysteries of Dead Sea Scrolls (Cell) 100 million year old bacteria under the sea (Nat Comm) Image credit Music used on TWiM is composed and performed by Ronald Jenkees and used with

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01:01:13

223: The smell of soil

This Week in Microbiology ·

2020/08/15

The TWiMmers explore detection of SARS-CoV-2 on surfaces in an ophthalmology examination room, the ability of stressed populations of Yersinia bacteria to survive antimicrobial treatment within host tissues, and how volatile organic chemicals produced by soil microbes attract arthropods which in turn disperse bacterial spores. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode SARS-CoV-2 RNA in ophthalmology

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01:19:04

222: Biosensors in bacteria

This Week in Microbiology ·

2020/07/30

Mark Martin joins TWiM to describe nano-sized parasitic bacteria that inhabit humans, and the construction of whole-cell biosensors for detecting arsenic in drinking water. Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt Guest: Mark O. Martin Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode Ultra-small parasitic bacteria in humans (Cell Rep) Arsenic (WHO) Arsenic and drinking water (CDC)

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01:08:47

221: Weapon of mucus destruction, WMD

This Week in Microbiology ·

2020/07/16

TWiM reveals a potential mucus-busting weapon for patients with cystic fibrosis, and bacteria in the intestinal tract that can oxidize cholesterol, leading to lower levels of the lipid in blood. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode Biofilm eradication with nitric oxide release (ACS Inf Dis) Pseudomonas quorum sensing network (Protein) Cholesterol metabolism by gut bacteria (Cell Host Microbe)

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43:14

220: From Mars to the vagina

This Week in Microbiology ·

2020/07/03

TWiM reveals that methane-producing bacteria might survive beneath the surface of Mars, and identification of a cytopathogenic toxin in a bacterium associated with preterm birth. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Become a patron of TWiM. Links for this episode: Archaea could make methane on Mars (Sci Rep) Cytopathogenic toxin in bacterium associated with preterm birth (J Bact) Music used on TWiM is composed and performed by Ronald Jenkees and used

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01:02:01

219: Commensal for a healthy skin

This Week in Microbiology ·

2020/06/19

The TWiM discusses eradicating racism in academia and STEM, and a peptide from commensal bacteria that protects skin from damage caused by MRSA Become a patron of TWiM Links for this episode: Responsibility in academic research Improving equity in faculty hiring (MBoC) #ShutDownSTEM Peptide protects skin from microbial damage (AAC) Agr phase variants in S. aureus (mBio) S. aureus quorum sensing system (BMC Res Notes) COVID-19 joins pandemic legion (mBio) Music used on TWiM is composed and

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01:02:03

218: The lengths SARS-COV-2 will go

This Week in Microbiology ·

2020/06/06

The TWiM team explains how breathing can transmit SARS-CoV-2, and how lack of breathing leads to loss of mitochondria in a multicellular parasitic animal. Become a patron of TWiM. Links for this episode: Reducing transmission of SARS-CoV-2 (Science) Why social distancing is important (NY Times) Parasite without mitochondria (PNAS) Letters read on TWiM 218 Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to

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51:36

217: The chronicles of narnaviruses

This Week in Microbiology ·

2020/05/22

The TWiM team explains an experimental vaccine to prevent E. coli urinary tract infections, and the remarkable three-way symbiosis of narnaviruses, bacteria, and fungi. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode Developing a vaccine for UTI (mBio) Narnaviruses and bacteria-fungal symbioses (ISME J) 20% off The Invisible ABCs for TWiM listeners! Use promo code: ABC20 at checkout. TWiM Listener

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01:03:35

216: It starts with a cough

This Week in Microbiology ·

2020/05/01

The TWiM team discuses saliva as more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swab and how Mycobacterium tuberculosis sulfolipid-1 activates nociceptive neurons and induces cough. Links for this episode: Preventing the next pandemic (NY Times) COVID-19 treatment guidelines (NIH) Saliva sensitive for SARS-CoV-2 detection (medRxiv) A mycobacterial molecule provokes cough (Cell) Letters read on TWiM 216 20% off The Invisible ABCs for TWiM listeners! Use promo

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56:44

215: Cultural transformation and pathogen emergence

This Week in Microbiology ·

2020/04/17

A ferret model for infection by SARS-CoV-2, and how Neolithization lead to emergence of a human bacterial pathogen. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Links for this episode: Infection and transmission of SARS-CoV-2 in ferrets (Cell Host Micr) Neolithization led to emergence of Salmonella enterica (Nat Ecol Evol) Arnold Demain (Wikipedia) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology

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58:37

214: Masterful subversion

This Week in Microbiology ·

2020/04/03

Vincent, Elio and Michael reveal the ASM COVID-19 summit, and how Salmonella injects a protein into the cell to drive suppression of the immune response. ASM COVID-19 Summit Value of SARS-CoV-2 diagnostic testing (mBio) How SARS-CoV-2 is changing (nextstrain) Contribute to COVID-19 data Salmonella effector suppresses inflammation (Cell Host Micr) Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM.

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01:01:17

213: Fugitive emissions

This Week in Microbiology ·

2020/03/20

Vincent, Elio and Michael discuss the stability of human coronaviruses on surfaces and in aerosols, and peptidoglycan production by a mosaic consisting of a bacterium within a bacterium within an insect. Links for this episode: Human coronavirus 229E infectivity on common surfaces (mBio) Aerosol and surface stability of SARS-CoV-2 (medRxiv) Peptidoglycan synthesis by a insect-bacteria mosaic (Cell) Letters read on TWiM 213 Become a patron of TWiM. Music used on TWiM is composed and performed by

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55:26

212: A coronavirus outbreak and IRF4 deficiency in...

This Week in Microbiology ·

2020/02/06

The TWiM team reviews the coronavirus outbreak that began in Wuhan, China, and the finding that an IRF deficiency underlies Whipple’s disease. 2019-nCoV case tracking (JHU) Clinical features of infection with 2019-nCoV (Lancet) Early transmission dynamics of 2019-nCoV (NEJM) Isolation of 2019-nCoV (NEJM) TLR4 defect in Whipple’s disease (eLife) Become a Patron of TWiM! Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions

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01:18:11

211: Bacteria, colon cancer and fire blight

This Week in Microbiology ·

2020/01/09

The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples. Become a patron of TWiM. Links for this episode: Colorectal cancer and the gut microbiome (PNAS) Fire blight (YouTube) Fire blight spreads north (NY Times) E. amylovora auxotrophs (Appl Environ Micro) Music used on TWiM is composed and

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01:16:24

210: The Waze of microbes

This Week in Microbiology ·

2019/12/05

The Microbial Comrades present the oldest osteosynthesis in history, and how a small molecule produced by stressed bacteria is a warning signal that repels healthy populations to promote their survival. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode P. aeruginosa PQS repels bacteria(J Bact) PQS signaling(J Bact) Letters read on

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58:18

209: Resuscitating persisters and flagellotrophic phage

This Week in Microbiology ·

2019/11/14

The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane. Become a patron of TWiM. Links for this episode: Ribosome modification resuscitates persister cells (Environ Micro) Flagellotrophic phage targets host with tail fiber (Mol Micro) Hydrodynamics of phage migration along flagella (Phys Rev Fluids) Music used on TWiM is composed and performed

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01:22:50

208: Georgia Tech microbial

This Week in Microbiology ·

2019/10/31

Hosts: Vincent Racaniello, Michele Swanson and Michael Schmidt Guests: Deanna Beatty, Mark Hay, Gina Lewin, Frank Stewart, and Marvin Whiteley At Georgia Tech, members and trainees of the Center for Microbial Dynamics and Infection discuss the identification of pathogen essential genes during coinfections, and how coral management can improve coral defenses against pathogens. Become a patron of TWiM. Links for this episode: Center for Microbial Dynamics and Infection Pathogen essential genes

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01:07:27

207: Partnerships to Advance Public Health

This Week in Microbiology ·

2019/10/17

From ASM Microbe 2019 in San Francisco, Vincent speaks with Victoria McGovern, Carl Nathan, and Dan Portnoy about advancing human health through innovative collaborations. Host: Vincent Racaniello Guests: Victoria McGovern, Carl Nathan, and Dan Portnoy Links for this episode: Getting grants (Virulence) Nitric oxide synthase protects against tuberculosis (PNAS) Actin filaments and Listeria monocytogenes (J Cell Biol) Become a Patron of TWiM! Music used on TWiM is composed and performed by Ronald

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01:05:17

206: Bacteria send nucleotide signals

This Week in Microbiology ·

2019/10/03

The TWiM holobionts pay tribute to Stuart Levy, and reveal the remarkably diverse array of cyclic nucleotides synthesized by bacteria that likely mediate interactions with animal and plant hosts. Become a patron of TWiM. Links for this episode: Stuart Levy, Antibiotic Resistance Researcher, Dies Resistance fighter (The Scientist) Stuart Levy on TWiM 16 Stuart Levy on Meet the Scientist episode 17 Segregation of R factors (Nature) Infectious drug resistance (Sci Am) Spread of antibiotic

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01:07:23

205: Asgards meet the Tardigrades

This Week in Microbiology ·

2019/09/20

The tetracoccal TWiM team visits Tardigrades on the Moon, and the twelve year quest to isolate an archaeon that provides insights into the emergence of the first eukaryotic cell. Links for this episode: Tardigrades on the moon (Mashable) Meet the Tardigrade (WaPo) Archaeon at prokaryote-eukaryote interface (bioRxiv) Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of

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345 results

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