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PODCAST

Springer Nature

Springer Nature

Welcome to the Springer Nature Soundcloud page! Here you will find several podcasts from our journals across a range of scientific subjects, including Gene Pod, ModPath Chat, Pediapod, Hereditypod and Brainpod.

science

All Episodes

00:13:34

April: miRNA expression in the pediatric dilated...

Springer Nature ·

2022/05/25

Dilated cardiomyopathy (DCM) is a rare but serious condition of children and often progresses to heart failure. The outcomes for children with DCM are poor, with 50% of pediatric patients dying or needing a heart transplant within 5 years of diagnosis. In this episode, Geoff Marsh meets professor Carmen Sucharov from the University of Colorado Anschutz campus and the director of the Pediatric Cardiology Research Laboratories. She and her team have been studying the regulation of micro-RNAs and

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00:07:04

A scientific approach to navigating the academic job...

Springer Nature ·

2022/05/09

Kirstie Cummings and Sofia Beas are both new assistant professors in the department of neurobiology at the University of Alabama, Birmingham. When they met, they discussed the job application process, their support network, and their own personal processes, and they decided to write an article that could serve as a resource for candidates from different backgrounds, many of whom might not have the same resources that Dr. Cummings and Dr. Beas did. The result was their paper, “A Scientific Approach

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00:15:23

Image-based assessment of extracellular mucin in...

Springer Nature ·

2022/05/04

Dr. Inti Zlobec, professor of digital pathology at the Institute of Pathology in the University of Bern, discusses her team’s recent publication in Modern Pathology on the role of image analysis in assessing area of extracellular mucin and predicting consensus molecular subtypes (CMS) in colorectal carcinoma. The utilized deep learning algorithm had an excellent agreement with pathologists’ estimates of mucin areas. Coupled with MSI, mucinous area estimates may predict CMS classification using only

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00:11:32

The fetal immune response to maternal SARS-CoV-2...

Springer Nature ·

2022/04/19

Thousands of women have been infected with SARS-CoV2 during the COVID-19 pandemic. While very few of these infections have been shown to transmit vertically from mother to offspring, it remains unclear what effect, if any, a mother's SARS-CoV2 infection has on fetal development. In this episode, we interview Dr Brian Kalish, from the University of Toronto and the Hospital for Sick Children to discuss a study he set up looking into this question, by characterising the composition and cell-type

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00:23:23

Grey reef shark demographics

Springer Nature ·

2022/04/13

Hidden within shark genomes are clues to the evolution of marine biodiversity hotspots. In this episode, Dr Paolo Momigliano (University of Vigo), tells us about his work on the grey reef shark: from fishing in the tropical waters of the Coral Triangle to detailed demographic modelling. This episode explores the recent Heredity paper: “Genomic insights into the historical and contemporary demographics of the grey reef shark” https://www.nature.com/articles/s41437-022-00514-4 To find out about the

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00:27:58

DP, WSI, AI, DL: The Alphabet Soup of the Third...

Springer Nature ·

2022/04/06

Traditional pathology have played an integral role in the delivery of diagnosis, semi-quantitative or qualitative assessment of protein expression, and classification of disease. Technological advances have recently paved the way for the development of digital pathology-based approaches for quantitative pathologic assessments, namely whole slide imaging (WSI) and artificial intelligence (AI)–based solutions, allowing us to explore and extract information beyond human visual perception. In this

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00:18:21

Recast: Getting to know Heredity

Springer Nature ·

2022/03/30

In this episode we revisit an inspiring episode that answers the question: why should you publish in Heredity?

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00:13:09

Galápagos giants

Springer Nature ·

2022/03/16

The giant tortoises of the Galápagos archipelago form one of the most iconic evolutionary systems in the world. But is all as it appears? Join Dr Evelyn Jensen (Newcastle University) and discover how museum specimens are reshaping our understanding of this famous radiation. This episode explores the recent Heredity paper: “A new lineage of Galapagos giant tortoises identified from museum samples” https://www.nature.com/articles/s41437-022-00510-8

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00:09:17

Identification of THC impairment using functional...

Springer Nature ·

2022/02/23

Driving while under the influence of THC, known as drugged driving, is becoming more of an issue as more states legalize cannabis for both medical and recreational use around the country. THC is known to impair cognitive and psychomotor performance and thus impair driving. Jodi Gilman is a neuroscientist and an associate professor of psychiatry at Mass General Hospital and Harvard Medical School, and she’s one of the authors of a new study in the journal Neuropsychopharmacology. She says that

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00:11:07

Wild barley relatives

Springer Nature ·

2022/02/23

Barley is one of the world’s oldest and most important cultivated cereal grains. But it’s long history of domestication has resulted in greatly reduced genetic diversity, which isn’t ideal for plant breeding efforts. So, in this episode, Che-Wei Chang and Prof. Karl Schmid (University of Hohenheim) discuss their quest to find useful genetic variation in wild barley relatives. This episode explores the recent Heredity paper: “Physical geography, isolation by distance and environmental variables

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00:11:09

Whole-exome sequencing of epilepsy after acute...

Springer Nature ·

2022/02/17

Twenty-five percent of children who survive acute symptomatic seizures as neonates go on to develop epilepsy. Whilst there are several known risk factors, currently not enough is known about the mechanisms behind the development of epilepsy following neonatal brain injury, and thus it is not yet possible to reliably predict the individual risk of developing this disease in this group of patients. In this episode, we speak to Adam Numis from UC San Francisco. He and his team used whole exome

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00:21:04

The best student-led papers in Heredity, Vol. 2

Springer Nature ·

2022/02/09

Every year Heredity publishes some outstanding student-led papers, and to recognise the quality of this work the journal runs a student paper prize. So, what makes a paper stand out? Find out, as we hear from overall winner Dr Allie Graham and 2nd runner-up Johanna Denkena. Explore the full Student Prize Longlist Collection here: https://www.nature.com/collections/bedbicdicb

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00:18:06

Genetic Purging

Springer Nature ·

2022/01/12

Inbreeding depression is often considered to be a bad thing, especially in conservation programmes. However, that may not always be the case. In this episode Dr Eugenio López-Cortegano (University of Edinburgh), Dr Eulalia Moreno (Estación Experimental de Zonas Áridas) and Prof. Aurora García-Dorado (Universidad Complutense de Madrid) discuss a surprising benefit of inbreeding in small, endangered populations. In this episode we explore the recent Heredity paper: “Genetic purging in captive

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00:11:09

PediaPod: A new technique for estimating respiratory...

Springer Nature ·

2022/01/10

Most very preterm infants experience apneas of prematurity. It is a common comorbidity of prematurity, and therefore reliable real-time monitoring of respiratory rates is key in these infants. The conventional method is to use chest impedance measured with electrodes on the surface of the thorax. However, this method is known to be unreliable, as it is prone to motion artifacts. For this reason, indirect measurements such as oxygen desaturation or bradycardia are often necessary to identify

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00:09:22

Brainpod: Evolution of the prefrontal cortex

Springer Nature ·

2022/01/10

In the past, there had been a school of thought that looked at evolution linearly — that is, you could in theory draw a line among mammals as they evolved, and so, say, rodent brains would basically be less evolved primate brains. That turns out not to be true; evolution is much more like a branching tree, and each branch then goes on to develop independently, sometimes in parallel. Some groups of animals such as primates can evolve features of their brains that other groups simply don’t have. And

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00:12:50

2021 Year in Review

Springer Nature ·

2021/12/28

In this episode of ModPath CHAT, Dr. George J Netto reviews five of the highly cited manuscripts that were published in Modern Pathology in 2021.

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00:13:14

Associations of media use and early childhood...

Springer Nature ·

2021/12/14

There is a growing body of evidence showing that excessive early media use is detrimental to children's physical and mental health. As such, the World Health Organization guidelines suggest that screen time for infants should be limited to a maximum of one hour per day. However, with the growing ubiquity of digital media, it is thought that preschoolers are exposed to more than two hours of screen time. With the rapidly changing nature of digital media use, it is not yet clear how this is affecting

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00:25:18

Surprising little lemurs

Springer Nature ·

2021/12/08

Join Prof. Anne Yoder (Duke University), Dr Mario dos Reis (Queen Mary University of London) and Dr George Tiley (Duke University) as they discuss their recent work looking at mutation rates in the gray mouse lemur. It’s a story that takes us from a house party to the bleeding edge of genetics research, with a detour through the scandalous sex lives of mouse lemurs. In this episode we explore the recent Heredity paper: “Pedigree-based and phylogenetic methods support surprising patterns of

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00:23:00

NTRK Fusions

Springer Nature ·

2021/12/07

Identification of molecular alterations in NTRK 1-3 has become increasingly important with the emergence of histology-agnostic, US Food and Drug Administration-approved, effective inhibitors. The host discusses with Dr. Jaclyn Hechtman, director of clinical diagnostic development at Neogenomics, her practical insights on how testing for NTRK fusion can best be implemented and communicated within the multidisciplinary healthcare team.

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00:05:33

Can the use of genetic testing improve the...

Springer Nature ·

2021/12/06

As cardiovascular disease has many known genetic components, a team of researchers at Baylor College of Medicine created a panel of genes associated with cardiovascular disease they call HeartCare. David Murdock, previously the assistant director of the clinical lab at Baylor College of Medicine’s Human Genome Sequencing Center and now a lab director at Invitae, states “we thought that by looking at genetic causes of cardiovascular disease in an adult population, that could really help us to push

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