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PODCAST

This Week in Microbiology

Vincent Racaniello

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows "This Week in Virology" (TWiV) and "This Week in Parasitism" (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

science life sciences

All Episodes

01:07:46

204: Programmable bacteria for antitumor immunity

This Week in Microbiology ·

2019/09/06

Host: Vincent Racaniello Guests: Nicholas Arpaia and Tal Danino Vincent meets up with Nick and Tal to explain how they engineered E. coli to lyse within tumors and deliver an antibody that causes tumor regression in mice. Links for this episode: Programmable bacteria induce tumor immunity (Nat Med) Synchronized cycles of bacterial lysis (Nature) TWiM Listener survey Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device

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58:19

203: A magnetotactic consortium under the sea

This Week in Microbiology ·

2019/08/22

The TWiM team reveals thousands of small novel genes in the human microbiome, and a mutualistic symbiosis between marine protists covered with magnetosome-containing bacteria. Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Links for this episode Thousands of small novel genesin human microbiome (Cell) A magnetotactic consortiumunder the sea (Nat Micro) Image credit Letters readon TWiM 203 Music used on TWiM is composed and performed by Ronald Jenkees and used with

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01:01:41

202: This frass doesn’t stink

This Week in Microbiology ·

2019/08/08

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt Guest: Julie Wolf Julie joins the TWiM team to reveal how microbiome and gut anatomy of a wood-feeding beetle promotes lignocellulose deconstruction, and bacteria that degrade PET plastic. How wood-feeding beetles deconstruct lignocellulose (PNAS) Meet the Microbiologist hosted by Julie Wolf Bacteria that degrade PET plastic (Micr Res Ann) Microbiology resource of the month (ASM) Morgan Vague’s TED talk Pacific

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01:23:57

201: Microbiology papers for first year students

This Week in Microbiology ·

2019/07/26

Mark Martin joins Vincent and Michael to present compelling papers suitable for teaching microbiology to undergraduate students. Become a patron of TWiM. Links for this episode: Paradigm shifts, paradigm drifts (pdf) Introducing THOR (mBio) Engineering bacteriophages to treat mycobacterial infection (Nat Med) Biofilms by Colter (Int Microbiol) Life in a world without microbes (PLoS Biol) Reduction of cholera in Bangladeshi villages (PNAS) Placenta goes viral (PLoS Biol) #OMG (jpg) #OMG illustration

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01:01:26

200: In the company of Elio

This Week in Microbiology ·

2019/07/12

Vincent, Michele, and Michael travel to San Diego to reminisce with Elio about his career, his work in microbiology, and his love for microbes and mushrooms. VIDEO VERSION AVAILABLE: https://www.youtube.com/watch?v=Menlo1YvPko Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email.Get the entire ASM Podcast Network via our Microbeworld app. Become a patronof TWiM. Links for this episode Elio’s profile Elio’s memoirs Elio’s first paper, 1952 (J Bact) In the Company

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01:15:16

199: PhD Balance

This Week in Microbiology ·

2019/06/28

From ASM Microbe 2019, the Microbials meet up with Susanna L. Harris and Alex Politis to talk about mental health in graduate school and NIH peer review. Hosts: Vincent Racaniello, Michele Swansonand Michael Schmidt Guests: Susanna L. Harrisand Alex Politis Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app. Become a patron of TWiM Links for this episode PhD Balance Susanna’s video(Vimeo) NIH Center

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01:00:23

198: Unexpectedly pathogenic bacteriophages

This Week in Microbiology ·

2019/06/01

The TWiM team presents an extracellular bacterium associated with Paramecium, and induction of antiviral immunity by a bacteriophage that prevents bacterial clearance. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Bacteria on the outside of paramecia (ISME) Phage trigger antiviral immunity (Science) Image credit Letters read on TWiM 198 Music used on TWiM is

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01:10:25

197: Intercellular microbial trade

This Week in Microbiology ·

2019/04/26

The Microbials reveal how a chemosynthetic symbiont stores energy for its marine flatworm host, and extraction of nutrients from host cells by E. coli injectisome components. Become a patron of TWiM. Links for this episode: Take the TWiM listener survey Bacteria store energy for gutless worms (PNAS) Paracatenula on TWiM #21 E. coli extracts nutrients from host cells (Cell) Image credit Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your

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01:03:38

196: I hear you

This Week in Microbiology ·

2019/03/29

The Microbials discuss how ambrosia beetles utilize ethanol to farm fungi, and how cleaved cochlin protein sequesters bacteria in the inner ear to preserve hearing function. Links for this episode: Ambrosia beetles, ethanol, and farmed fungi (PNAS) Cleaved cochlin protects the inner ear (Cell Host Microbe) Importance of flossing (ADA) Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app

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01:14:32

195: Gingipain in the Alzheimer brain

This Week in Microbiology ·

2019/03/04

Michael and Vincent discuss the finding of immunity to Cas9 protein in humans, and a potential role for an oral bacterium in Alzheimer’s disease. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email.Get the entire ASM Podcast Network via our Microbeworld app. Become a patron of TWiM. Links for this episode Immunity to Cas9 protein in humans (Nat Med) P. gingivalis and Alzheimer’s disease (Science) Clinical trial of COR388 in AD patients (clinicaltrials.gov)

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01:05:27

194: Standard imperial procedure

This Week in Microbiology ·

2019/02/14

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter How a bacterium helps dengue virus replicate in the mosquito gut, and minicells as a damage disposal mechanism in E. coli. Become a patron of TWiM. Links: Please take the TWiM listener survey Bacteria help dengue virus in mosquito gut (Cell Host Micr) Fungus helps dengue virus in mosquito gut (TWiV 479) Minicells for disposal of damaged goods (mSphere) TWiM Listener survey Subscribe to TWiM (free) on iTunes, Google

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01:00:45

193: Persisters

This Week in Microbiology ·

2019/01/31

The TWiM team explore how Lactobacillus reuteri can rescue social deficits in three mouse models of autism spectrum disorder, and the role of Salmonella persisters in undermining host defenses during antibiotic treatment. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. Become a Patron of TWiM! Please take the TWiM listener surveyBacteria alter behavior in mouse autism models (Neuron) Mice behaving badly (TWiM 131) Salmonella persisters undermine host

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01:06:22

192: A Qtip for phages

This Week in Microbiology ·

2019/01/18

The TWiM team reveals an extremely low rate of mutation in a 2500 year old, 185 acre fungus in Michigan, and how a host-produced quorum sensing autoinducer controls the phage switch between lysis and lysogeny. Please take the TWiM listener survey Vote for NJ State Microbe Huge fungus is 2500 years old (Proc Roy Soc B) Humongous fungus (Wikipedia) Host-produced autoinducer controls phage (Cell) These bacteria are bugged (virology blog) Subscribe to TWiM (free) on iTunes, Google

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01:01:36

191: By the pulp of their teeth

This Week in Microbiology ·

2018/12/21

The TWiM team reveals the oldest human plague from 4,900 years ago in Sweden, and engineering E. coli to become an endosymbiont in yeast, modeling the evolution of mitochondria. Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app. Become a patron of TWiM. Links for this episode Oldest human plague from 4,900 years ago

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01:18:51

190: Exosomes in your nose and in your gut

This Week in Microbiology ·

2018/12/07

The TWiM-opods consider two stories about exosomes, vesicles that are shed from cells: those that eliminate airway pathogens, and those from the plants we eat that shape our gut microbiome. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app. Become a patron of TWiM. Links for this episode Exosome swarms eliminate airway pathogens (J Aller

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01:11:05

189: Salmonella BonJovi

This Week in Microbiology ·

2018/11/16

The TWiM team considers the state of the world’s fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses. Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson Take our listener survey. Thanks! asm.org/twimpoll Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Links for

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01:20:45

188: Turducken antibiotics

This Week in Microbiology ·

2018/10/31

The TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome. Hosts: Vincent Racaniello and Michael Schmidt Links for this episode Antibiotics for gram-positives that kill gram-negatives (J Med Chem) Sideromycin commentary (Am Council Sci Health) Bacterial genome with DNA and RNA (J Am Chem Soc) Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM

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01:06:29

187: Rounding up the bees

This Week in Microbiology ·

2018/10/19

The TWiM people reveal that phages must cooperate to overcome CRISPR-Cas defenses, and the effect of the herbicide glyphosate on the gut microbiome of honey bees. Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Links for this episode: Phages Cooperate to Overcome CRISPR-Cas Immunity

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01:13:24

186: Crypto-metamorphosis

This Week in Microbiology ·

2018/10/05

The TWiM team describe the involvement of a microbiome in snail metamorphosis, and using Listeria to kill tumors. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app. Become a Patron of TWiM! Links for this episode Infectious diseases after Florence (Med Inf Dis) Cryptic niche switching in gastropod (Proc Roy Soc B) Metamorphosis then no

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01:08:22

185: There’s no moa Moa

This Week in Microbiology ·

2018/09/21

The TWiM team considers the increasing tolerance of Enterococcus to handwash alcohols, and how the study of DNA in ancient dung reveals the diet and parasite burden of extinct New Zealand birds. Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Episode Links: Hand sanitizer alert (Emerg Inf Dis) Bacteria becoming hand sanitizer tolerant (NPR) Increasing tolerance of

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