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PODCAST

The Life Scientific

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future

science personal journals

All Episodes

34:48

Brian Greene on how the universe is made of string

The Life Scientific ·

2020/04/28

Jim talks a man who studies the universe at the largest and smallest scales imaginable. When Brian Greene was just twelve years old, he wandered round Columbia University in New York looking for someone to teach him mathematics, with a letter of recommendation from his school teacher. While his mother wanted him to make money, his father encouraged Brian to pursue his passion, which was trying to understand the nature of the universe. He studied physics at Harvard University and won a Rhodes

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36:16

Myles Allen on understanding climate change

The Life Scientific ·

2020/03/04

Professor Myles Allen has spent thirty years studying global climate change, trying to working out what we can and can't predict. He was one of the first scientists to quantify the extent to which human actions are responsible for global warming. As a lead author on the 3rd Assessment by the International Panel on Climate Change in 2001, he concluded that ‘most of the observed global warming was due to human influence’. More recently, (having established that calculating a safe concentration of

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29:57

Matthew Cobb on how we detect smells

The Life Scientific ·

2020/03/03

It’s been estimated that humans are capable of detecting a trillion different smells. How is this possible when we have just 400 types of olfactory receptors located in the bridge of our nose? Matthew Cobb has spent many years studying maggots hoping to get to bottom of this problem. He spent several years studying the flirting rituals of fruit flies in Sheffield before moving to France to study at the world centre for fly research, not far from Paris. There are, of course, a lot of differences

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28:09

Anya Hurlbert on seeing colour

The Life Scientific ·

2020/03/02

As a professor of visual neuroscience at Newcastle University, Anya Hurlbert is one of our most respected researchers into the way we see colour. In a career as a physicist, physiologist, neuroscientist and physician at some of the great research institutes on both sides of the Atlantic, Anya’s investigations into how we perceive the colour of objects has transformed our view of how our predominantly visual brains function. She explains how the multidisciplinary approach to research in vision from

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33:55

Optical communications pioneer Polina Bayvel

The Life Scientific ·

2020/02/11

We’ve come to expect to be connected instantly to anywhere in the world and to have unlimited information at our fingertips. We shop online, stream music, download books and boxsets onto our electronic devices. We share videos of our pets just because we can. But how much time have you spent recently thinking about the remarkable feats of engineering that make all this possible? Polina Bayvel has been at the forefront of creating the optical fibre networks that are capable of transporting vast

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28:27

2019 Nobel Prize winner for Physiology or Medicine,...

The Life Scientific ·

2020/02/04

Sir Peter Ratcliffe, Director of Clinical Research at the Francis Crick Institute, as well as Director of Oxford University’s Target Discovery Institute – has dedicated his life to understanding the body’s molecular-level response to low oxygen levels, or ‘hypoxia’. He received the 2019 Nobel prize for Physiology or Medicine, along with two Americans, William Kaelin of Harvard and Gregg Semenza of Johns Hopkins, for successfully tackling one of physiology’s greatest puzzles - how our bodies sense

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36:10

Peter Fonagy on a revolution in mental health care

The Life Scientific ·

2020/01/28

Peter Fonagy arrived in the UK from Hungary aged 15, not speaking a word of English. His family was in Paris. He was bullied at school, failed every exam and thought of ending his life. Therapy saved him, he says. Years later, he trained to be a clinical psychologist and then a psychoanalyst. His research on attachment styles between a mother and her baby (which can be healthy, anxious or avoidant) was ground breaking. He went on to show that the human need to be understood runs very deep indeed

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32:22

Susannah Maidment on stegosaurs

The Life Scientific ·

2020/01/14

Susie was dinosaur-mad as a child. But unlike most children, she never grew out of her obsession. She tells Jim about an exciting new stegosaur find in the Atlas Mountains in Morocco and describes the time she spent dinosaur hunting (with a toddler in tow) in the Morrison Formation in the American Mid-West: a place where there are thought to be enough dinosaur remains to keep a thousand paleontologists happy for a thousand years. She is at her happiest out in the field, with a hammer and a

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33:13

Patricia Wiltshire on how pollen can solve crimes.

The Life Scientific ·

2020/01/07

Patricia Wiltshire grew up in a mining village in South Wales, left home when she was 17 and worked for many years, first as a medical technician and then as a business secretary (a profession her first husband considered to be more ladylike). When she was studying botany A level at evening classes, her teacher encouraged her to apply for university as a mature student. (She would never have considered it otherwise). And so began her career as a palynologist (studying pollen). She worked for many

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28:02

Elizabeth Fisher on chromosomes in mice and men

The Life Scientific ·

2019/11/12

Elizabeth Fisher, Professor of Neurogenetics at University College London, spent 13 years getting her idea – finding a new way of studying genetic disorders – to work. She began her research career at a time, in the 1980s, when there was an explosion of interest and effort in finding out what genes did what, and which of them were responsible for giving rise to the symptoms of various neurodegenerative conditions. Elizabeth has been particularly interested in those in which there are chromosomal

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32:39

Demis Hassabis on artificial intelligence

The Life Scientific ·

2019/11/05

In the 200th episode of The Life Scientific, Jim Al-Khalili finds out why Demis Hassabis wants to create artificial intelligence and use it to help humanity. Thinking about how to win at chess when he was a boy got Demis thinking about the process of thinking itself. Being able to program his first computer (a Sinclair Spectrum) felt miraculous. In computer chess, his two passions were combined. And a lifelong ambition to create artificial intelligence was born. Demis studied computer science at

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28:25

Saiful Islam on materials to power the 21st century

The Life Scientific ·

2019/10/29

Not so long ago, all batteries were single use. And solar power was an emerging and expensive technology. Now, thanks to rechargeable batteries, we have mobile phones, laptops, electronic toys, cordless power tools and other portable electronic devices. And solar power is reducing our reliance on carbon-based fossil fuels. None of this would have been possible without a deep understanding of the chemistry of materials that have particular properties – the ability to turn sunlight into energy for

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28:46

Adrian Owen on scanning for awareness in the injured...

The Life Scientific ·

2019/10/22

Neuroscientist Adrian Owen has spent much of his career exploring what he calls ‘the grey zone’, a realm of consciousness inhabited by people with severe brain injuries, who are aware yet unable to respond to those around them. It's this inability to respond which has led doctors to conclude that they are unaware. In the late 1990's, Adrian started to question the assumption that they lacked awareness and a chance discovery set him on a novel path of enquiry - could some of these patients be

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34:55

Martha Clokie on the viruses that could improve our...

The Life Scientific ·

2019/10/15

Could viruses improve our health where antibiotics have failed? As a child, Martha Clokie spent a lot of time collecting seaweed on Scottish beaches. She loves plants and studied botany for many years. But mid-career, she learnt about all the viruses that exist in nature. We tend to focus on the viruses that make us ill but there are trillions of viruses on earth and in the ocean and most of them eat bacteria. When a virus destroys a bacteria that attacks our bodies, then it could be just what the

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27:42

Anne Magurran on how to measure biodiversity

The Life Scientific ·

2019/10/08

Anne Magurran started her career as an ecologist counting moths in an ancient woodland in northern Ireland in the 1970s, when the study of biological diversity was a very young science. Later she studied piranas in a flooded forest in the Amazon. Turning descriptions of the natural world into meaningful statistics is a challenge and Anne has pioneered the measurement of bio-diversity. It’s like an optical illusion, she says. The more you think about bio-diversity the more difficult it is to define

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28:21

Richard Wiseman on lying, luck and the paranormal

The Life Scientific ·

2019/10/01

How do you tell if someone is lying? When Richard Wiseman, Professor of the Public Understanding of Psychology at the University of Hertfordshire, conducted a nationwide experiment to identify the tell-tale signs, the results were surprising. If you want to spot a liar, don’t look at them. Listen to what they say and how they say it. in If you want to distinguish fact from fiction, radio, not TV or video is your friend. Visual cues distract us from what is being said and good liars can

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27:55

Jonathan Ball on his arms race against viruses

The Life Scientific ·

2019/07/30

Ebola, Zika, Sars, Mers - rarely a week goes by without a deadly virus stealing the headlines. For Jonathan Ball, getting to know a virus at its most basic level is crucial to mounting a defence. As the son of a coal miner, who grew up in a mining village in the 1970s, a future in academic research studying deadly viruses wasn’t really on the agenda. Yet his work has led him to the forefront of scientific research to find the antibodies that can protect us from some of the nastiest diseases known

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27:35

Robin Dunbar on why we have friends

The Life Scientific ·

2019/07/23

Maintaining friendships is one of the most cognitively demanding things we do, according to Professor of Evolutionary Psychology Robin Dunbar. So why do we bother? Robin has spent his life trying to answer this deceptively simple question. For most of his twenties, he lived with a herd of five hundred gelada monkeys in the Ethiopian highlands. He studied their social behaviour and concluded that an ability to get on with each other was just as important as finding food, for the survival of the

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29:25

Katherine Joy on moon rock

The Life Scientific ·

2019/07/16

Katherine Joy studies moon rock. She has studied lunar samples that were brought to earth by the Apollo missions (382kg in total) and hunted for lunar meteorites in Antarctica, camping on ice for weeks on end and travelling around on a skidoo. Working at the forefront of the second wave of lunar exploration, she studied remote sensing data from Europe’s first mission to the moon, Smart 1 which launched in 2003 and data from many subsequent missions. She tells Jim Al-Khalili why she believes the

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28:50

DNA detective Turi King

The Life Scientific ·

2019/07/09

When a skeleton was unearthed in 2012 from under the tarmac of a car park in Leicester, Turi King needed to gather irrefutable evidence to prove that this really was the body of Richard III, England's infamous medieval monarch. Under the microscope was not only the king's genetic identity, but his entire reputation. Was Richard a ruthless villain, as depicted by Shakespeare? Or did the incoming Tudors spread 'fake news' to besmirch his name? As Jim discovers, clues in his skeletal remains have

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