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PODCAST

The Effective Statistician - in association with PSI

Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry

The podcast from statisticians for statisticians to have a bigger impact at work. This podcast is set up in association with PSI - Promoting Statistical Insight. This podcast helps you to grow your leadership skills, learn about ongoing discussions in the scientific community, build you knowledge about the health sector and be more efficient at work. This podcast helps statisticians at all levels with and without management experience. It is targeted towards the health, but lots of topics will be

science natural sciences

All Episodes

38:37

Myths About Leadership You Shouldn't Believe

The Effective Statistician - in association with PSI ·

2023/07/31

You have to be extroverted to be a leader. Only if you have employees are you a leader. Either you have it or you don't. Leaders have a natural gift, you can't learn it. Those are three typical myths about leaders. In today's episode, I talk with Gary about these three false beliefs. We point out why they're false and give some counterexamples. We also discuss why they limit your development and make you a victim, so to speak. As statisticians, we are often introverted. We can use this to our

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28:55

Three Things to Learn About Yourself That Will Make a...

The Effective Statistician - in association with PSI ·

2023/07/24

Personal growth is an integral part of every individual’s life. It is a continuous process of self-improvement, learning, and self-discovery. As a statistician or statistician enthusiast, you should always be on a quest for personal and professional development. The journey towards growth is unique, and understanding yourself is a critical step towards achieving your potential. In this 300th episode, I discuss the three things about yourself that could make a significant difference in your career

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51:24

Taking Out the Pain of Paperwork: How Sponsors and...

The Effective Statistician - in association with PSI ·

2023/07/17

Transcript [00:00:00] Alexander: Welcome to a new episode of The Effective Statistician, and today I'm super excited to talk with Sheila about her project that I think is a really important part in the overall puzzle of developing new medicines, new diagnostics, and all kind of other things in our world of healthcare. Welcome to the show, Sheila. [00:00:30] Sheila: Thanks Alexander. So happy to be here and thank you for the kind words of intro. [00:00:35] Alexander: Yeah. Maybe for those who don't

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35:20

Driving Statistical Innovation - Barriers And...

The Effective Statistician - in association with PSI ·

2023/07/10

In part 1 of this series, we explored the perspectives on commercializing statistical inventions, leveraging external resources, collaboration, and setting up a community of statistical methodology leaders. Innovation is essential for advancing drug development, and statisticians play a vital role in driving statistical innovation. However, to overcome the barriers to innovation, statisticians need to work together, share information openly, and cultivate a culture of curiosity and

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25:20

Driving Statistical Innovation - Barriers And...

The Effective Statistician - in association with PSI ·

2023/07/03

Statistical innovation is vital in the pharmaceutical industry as it drives evidence-based decisions and brings value to patients. However, it requires a delicate balance between invention and commercialization to achieve success. I, together with Mouna Akacha and Kaspar Rufibach - two leaders of statistical innovation groups in big pharma companies, share their insights on the barriers and strategic planning in driving statistical innovation. In this first part of the episode, we will discuss

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9:44

Your Compound Through the Eyes of the Competition

The Effective Statistician - in association with PSI ·

2023/06/26

In any industry, staying competitive and relevant requires a constant focus on innovation and the ability to communicate effectively with customers. In the pharmaceutical industry, this is particularly true as companies race to develop and market new compounds that can improve patient outcomes. In this episode, I share insights into the importance of effective data communication for success in this industry. Specifically, I discuss an experience with helping a competitor with their need to

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6:48

Do You Still Focus on SAS Alone?

The Effective Statistician - in association with PSI ·

2023/06/19

As a statistician, you're likely already familiar with SAS and the value it brings to data analysis. But in this ever-evolving world of data science, relying on your go-to language might not be enough to stay competitive anymore. The open-source language R is gaining traction within many industries as a powerful tool for analyzing complex datasets. In this episode, join me while I talk about why learning R can help you stay ahead of the game—and why now is the perfect time to dive into its growing

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33:56

Framework for Estimating Policy Estimands

The Effective Statistician - in association with PSI ·

2023/06/15

In the world of statistics, information can sometimes be missing in data sets, leading to a challenge in understanding how well treatments may work. Policy estimands are used to understand efficacy based on early treatment decisions. Various approaches, like reference-based imputation and delta adjustment, exist to speculate what may have happened after treatment was discontinued. However, these methods are often inconsistent, and more efficient methods are required. In this episode, Alberto and I

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7:58

Beyond Regulatory and HTA Success: Reaching...

The Effective Statistician - in association with PSI ·

2023/06/08

Statisticians play a significant role in the clinical development of pharmaceutical products and medical devices. Their primary focus is to design and analyze clinical trials to provide evidence for regulatory approval and Health Technology Assessment (HTA). However, despite their valuable contributions, statisticians rarely get the chance to communicate directly with physicians, caregivers, and patients, the last hurdle in the medical affairs of pharmaceutical products. Communication often relies

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39:52

Interpretable Machine Learning

The Effective Statistician - in association with PSI ·

2023/06/05

Interpretable machine learning (IML) is rapidly gaining popularity in the data science community. It offers a new way to build and interpret models that are more transparent and understandable. In this episode, we have the privilege of interviewing Serg Masis. Serg authored the book "Interpretable Machine Learning with Python: Learn to build interpretable high-performance models with hands-on real-world examples". You'll see, that this concept not only applies to very complex models but even to

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37:38

Simulations - Your Most Powerful Study Design Tool

The Effective Statistician - in association with PSI ·

2023/06/01

When it comes to clinical trial design, there are many challenges to overcome, including recruitment, protocol design, and data analysis, among others. Fortunately, simulations can provide a solution to some of those challenges. Simulations allow researchers to test hypotheses, optimize designs, and understand probabilities of success before running the real-world experiment. Together with Kim Hacquoil and Jamie Inshaw in this episode, we discuss the benefits of using simulations as a study design

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30:44

PSI Book Club - Dare To Lead Review

The Effective Statistician - in association with PSI ·

2023/05/29

In today's highly competitive work environment, developing leadership skills such as vulnerability and empathy can mean the difference between success and failure. In this podcast episode, Marius and I discuss Brené Brown's "Dare to Lead," a book that dives into the importance of vulnerability-based leadership. This episode will explore some of the key takeaways from the book and how they can be applied in the work environment. We also discuss the following points:

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45:27

Introduction to Clivoffective

The Effective Statistician - in association with PSI ·

2023/05/22

The field of statistics is rapidly growing, and statisticians play an important role in providing a competitive advantage to companies. However, finding the right job or candidate for a position can be challenging. That's where Clivoffective comes in - a collaboration between Clivolution and The Effective Statistician focused on connecting statisticians with career opportunities. If you're a statistician or hiring manager in the field, Clivoffective offers a personalized touch that sets it apart

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30:28

Killer Statistician

The Effective Statistician - in association with PSI ·

2023/05/15

In the field of statistics, we need specific skills necessary for being successfull. Debarshi Dey, currently the head of the Statistics and Programming and Data Management department at Morphosys, has spent the past 13 years in the pharmaceutical industry. With a PhD in statistics from UC Riverside, Debarshi believes that to be a "killer statistician," one must adopt the roles of a detective, lawyer, and storyteller. Debarshi and I discuss these key characteristics that make a statistician

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48:25

How To Get Our Statistics Community to the Next Level

The Effective Statistician - in association with PSI ·

2023/05/08

We statisticians have always been important for brining new therapies to patients. We design experiments, analyze and interpret data to provide valuable insights that can help make informed decisions. However, the value of our work increases if we're able to lead others. But becoming an inspirational statistician requires more than just technical expertise. As you continue to grow in your career, don't forget to invest in yourself by learning from training programs, books, movies, and other

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21:12

5 Reasons for Career Failure

The Effective Statistician - in association with PSI ·

2023/05/02

Are you a statistician or data scientist looking to excel in your career and make an impact in the healthcare industry? Today's episode is inspired by a German podcast that delved into five key reasons for career failure and I fine-tuned this to fit statisticians. As professionals working with complex projects and tight deadlines, it's important that we recognize these pitfalls before they cause irreparable damage to our success. Join us as we explore each of these five potential hazards, discuss

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19:37

Announcing The Effective Statistician Academy

The Effective Statistician - in association with PSI ·

2023/04/25

If you're a statistician, data scientist, or programmer looking for quality training opportunities that will help you advance your career, you might want to look into The Effective Statistician Academy. This exclusive academy offers a range of courses that cover essential topics in the field of statistics. From leadership to innovation, knowledge, and excellence, you're sure to find a course that fits your needs and goals. The Effective Statistician Academy offers four distinct areas of training:

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25:29

Setting Expectations - an Art and a Science

The Effective Statistician - in association with PSI ·

2023/04/18

What strategies do you use in your work as a statistician to ensure successful outcomes? How do you set expectations with stakeholders when tackling a project? Are there any common mistakes statisticians make when setting expectations in their job that you have learned to avoid? How setting realistic expectations can positively impact your work as a statistician? As I embark on this journey of discussing expectations, it reminds me of an incident that happened to me recently. During one of my

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22:00

How to Avoid Bad Quality from Programmers and Data...

The Effective Statistician - in association with PSI ·

2023/04/11

As statisticians, we rely on good quality from programmers and data management. And if you talk to your colleagues, everybody has a story about a poor experience. But the questions are: How do we collaborate with other departments to create a quality deliverables? How to strike the right balance between working on processes and managing people for maximum efficiency? How to we take ownership and drive responsibility to learn from mistakes and not blaming each other? Tension often arises between

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36:34

Bayesian Approaches in Early Clinical Research

The Effective Statistician - in association with PSI ·

2023/04/05

What knowledge gaps exist regarding the implementation of these new analytical techniques, and how can statisticians and data scientists bridge them to maximize effectiveness of clinical research? Despite the promises of Bayesian approaches, the lack of expert training, software tools, and computational resources has made their adoption slow. Statisticians and data scientists should invest in training programs to enhance their skills in Bayesian modeling, use open-source software for Bayesian

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