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PODCAST

Oncology for the Inquisitive Mind

Michael Fernando and Josh Hurwitz

Cancer is a fascinatingbut rapidly evolvingdiscipline- it"s a full-time job just keeping up to date. In this podcast,Dr Michael Fernando and Dr Joshua Hurwitz explorethe latest trials, research, and practice-changing updates,as well asregular interviews with renowned oncology specialists.Ideal for thosestarting their trainingjourney, established specialistsandanyone interested in medical science, oncological practice,or terrible jokes. Preferably all three. Hosted on Acast. See acast.com/privacy for

health & fitness medicine

All Episodes

55:46

14. Advanced Ovarian Cancer

Oncology for the Inquisitive Mind ·

2022/11/05

After the highs of their special interview with Dr Belinda Yeo on all things breast cancer, Josh and Michael crash back to their usual programming with a banter and dad-joke-filled journey through the treatment of advanced ovarian cancer. A notoriously insidious disease, ovarian cancer is responsible for not just significant mortality but soul-crushing morbidity as well. However, for some very special people, ovarian cancer does not stop them from reaching their goals, up to and including completing

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1:02:17

13. Breast Cancer with Dr Belinda Yeo

Oncology for the Inquisitive Mind ·

2022/10/29

To celebrate the end of breast cancer awareness month, Michael and Josh are joined by Dr Belinda Yeo, an experienced oncologist specialising in treating breast cancer. Belinda trained at St Vincent's Hospital in Sydney, Australia, followed by the Royal Marsden Hospital in London. She now works at the Olivia Newton-John Cancer Research Institute as a Clinician Scientist with a specific interest in breast cancer and the prestigious Austin Hospital in Melbourne, Australia.We discussed all things breast

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41:05

12. Metastatic Pancreatic Cancer

Oncology for the Inquisitive Mind ·

2022/10/22

In this episode, Josh and Michael take a step down from the dizzying heights of HER-2 positive breast cancer treatment and crash back to earth to metastatic pancreatic cancer, a topic that remains an unconquered Everest, mocking oncologists like that one kid who always stole Josh's lunch money in school... Don't worry; there will be no airing of childhood trauma here. Just two oncologists discussing treatments and casting a hopeful eye towards the future.Links to studies discussed in this episode

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47:04

11. Metastatic HER2- Positive Breast Cancer

Oncology for the Inquisitive Mind ·

2022/10/15

In part two of their HER2 breast cancer dive, Josh and Michael explore the optimistic world of metastatic breast cancer. Once a desolate space with limited options, HER2 metastatic breast cancer represents the frontier of targeted therapy, like the industrial age or landing on the moon. While neither Josh nor Mikey have been to the moon, these researchers have landed among the stars bringing hope and effective treatments to an aggressive tumour time that a decade ago would have had a very different

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1:01:05

10. Early HER2-Positive Breast Cancer

Oncology for the Inquisitive Mind ·

2022/10/08

In this episode, Josh and Michael begin their second two-part expedition, this time exploring HER2-positive breast cancer, an area of oncology that has been much like your favourite Instagram or TikTok celebrity: at the forefront of the hottest new trends. Neither Josh nor Mikey have a favourite Instagram or TikTok celebrity because they are old and out of touch, but the shifts in HER2-positive breast cancer may be their favourite oncological TikTok celebrity. For the reasons behind such a stretched

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39:48

9. Metastatic Urothelial Cancer

Oncology for the Inquisitive Mind ·

2022/10/01

In this episode, Josh and Michael once again tackle immunotherapy in its application to metastatic urothelial cancer. Some say immunotherapy should be used up front. Others say that it should be used when all previous treatments have failed. And still, others are wondering about that Richard Nixon/Spock impression from last week and how it could be topped. For answers to all those questions and more, you'll have to listen on...Links to papers discussed in this episode (subscription may be

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1:14:17

8. ESMO 2022 Highlights

Oncology for the Inquisitive Mind ·

2022/09/24

In this extraordinary episode, Josh and Michael continue their journey to the earth's centre and the unknown with more European Society of Medical Oncology (ESMO) highlights.Since last week, Michael has realised that his French needs a bit of work, so they stuck to their guns and avoided google translate. Josh feels they should work on their Spanish to prepare for ESMO in Madrid in 2023. But before these dashing young Doctors get too excited for next year, more pivotal studies must be reported for

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50:53

7. ESMO 2022 Highlights

Oncology for the Inquisitive Mind ·

2022/09/17

In this very special episode, Josh and Michael hope to fulfil their fantasy of attending the European Society of Medical Oncology's (ESMO) yearly Congress, where they rub elbows with oncology's biggest movers and shakers; learn about the latest groundbreaking studies; and, in Michael's case, speak French with an accent lifted from a Monty Python sketch. The fact that they were stuck at home for the entire conference won't stand in the way of them from highlighting some of the best, most exciting

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52:19

6. Hepatobiliary Cancer

Oncology for the Inquisitive Mind ·

2022/09/10

"Hepatobiliary cancer, the final frontier." So begins our double-headed sojourn into two of the most challenging to-treat cancers many oncologists will encounter, but one that ends on a surprisingly positive note. Also, there's a cameo that absolutely no one will see coming...Links to studies discussed in this episode (subscription may be required):TOPAZ-1: https://evidence.nejm.org/doi/full/10.1056/EVIDoa220001IMbrave150: https://www.nejm.org/doi/10.1056/NEJMoa1915745Barcelona Liver Cancer Staging:

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1:02:34

5. Early Hormone Receptor-Positive Breast Cancer

Oncology for the Inquisitive Mind ·

2022/09/03

In episode 5, Michael and Josh dive into the complex world of hormone receptor-positive breast cancer. While early-stage breast cancer boasts fantastic cure rates many other cancers can only dream of, this evolving space must contend with multiple players, including aromatase inhibitors, tamoxifen and now abemaciclib (CDK 4/6 inhibitor). How best to approach adjuvant endocrine therapy is difficult, but Michael and Josh are on the case!Links to papers discussed in this episode (subscription may be

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49:19

4. Metastatic Non-Small Cell Lung Cancer

Oncology for the Inquisitive Mind ·

2022/08/27

Four episodes already! How time flies when you're having fun. In this episode, Josh and Michael discuss metastatic lung cancer, an area of oncology where a survival benefit of a few months generates cheers, tears and standing ovations. So what happens when studies start to improve patients' outcomes by YEARS? I don't know, but there were almost certainly minds that were thoroughly blown. Join us for this most optimistic of episodes!Links to papers discussed in this episode (subscription may be

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31:38

3. Mesothelioma

Oncology for the Inquisitive Mind ·

2022/08/20

In this episode, Michael and Josh discuss the scourge that is metastatic mesothelioma. This genuinely awful disease continues to inflict significant mortality and morbidity on patients exposed to asbestos worldwide. One of our more grim episodes thus far, but never fear; we have still crammed in more dad jokes than one can wave a bag of chemotherapy at.Links to papers discussed in this episode (subscription may be required):Vogelzang et al (2003):

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49:33

2. Metastatic Melanoma

Oncology for the Inquisitive Mind ·

2022/08/13

In this episode, Josh and Michael discuss the incredible story of the treatment of metastatic melanoma, the immunotherapy revolution, and why this relegated a perfectly decent targeted therapy to second place on the podium. Join us for a titanic battle on a par with Macbeth vs Macduff, Rocky Balboa vs Apollo Creed, or Regina George vs that bus...Links to papers discussed (subscription may be required):CHECKMATE-067: https://www.nejm.org/doi/full/10.1056/nejmoa1910836COMBI-D:

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42:51

1. Hormone Sensitive Prostate Cancer

Oncology for the Inquisitive Mind ·

2022/08/06

In their inaugural episode, Michael and Josh discuss one of the most common cancers a budding oncologist will encounter: prostate cancer. But is there more to this cancer than meets the eye? Will they make sense of the whole confusing mess? Is this whole podcasting thing way too much for them to handle? Listen on to find out!Links to papers discussed (subscription may be required):CHAARTED: https://www.nejm.org/doi/full/10.1056/nejmoa1503747ENZAMET:

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1:48

Introducing: Oncology for the Inquisitive Mind

Oncology for the Inquisitive Mind ·

2022/07/31

Cancer is a fascinatingbut rapidly evolvingdiscipline- it's a full-time job just keeping up to date. In this podcast,Dr Michael Fernando and Dr Joshua Hurwitz explorethe latest trials, research, and practice-changing updates,as well asregular interviews with renowned oncology specialists.Ideal for thosestarting their trainingjourney, established specialistsandanyone interested in medical science, oncological practice,or terrible jokes. Preferably all three.For more episodes, resources and blog

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