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PODCAST

Smart Biotech Scientist | The CMC and Biomanufacturing Podcast for Bioprocess Development and Manufacturing Leaders

David Brühlmann - CMC Development Leader, Bioprocess Expert, Business Strategist

The go-to CMC and bioprocessing podcast for process development scientists and CMC leaders scaling biologics into regulatory-ready therapies with less trial and error.Practical, execution-focused guidance on CMC development, tech transfer, scale-up, GMP readiness, CDMO partnerships, and manufacturing economics.Hosted by Dr. David Brühlmann, CMC strategist, former Bioprocess Innovation Manager at Merck, PhD in glycoengineering, and close to 20 years of biomanufacturing experience. Smart Biotech

science life sciences

All Episodes

19:22

61: Magnetic Bead Technology: The New Era in...

Smart Biotech Scientist | The CMC and... ·

2024/06/11

Dive into the latest episode as we explore how magnetic bead technology is revolutionizing downstream processing, promising higher yields and greater purity.Our guest, Nils Brechmann, Marketing Manager at MAGic BioProcessing and co-inventor of the process applications, shares his insights on overcoming industry challenges and the future of purification. MAGic BioProcessing is a biotech company from Uppsala, Sweden, that develops magnetic-based recovery of biologicals.Key Takeaways:Discover ho...

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20:37

60: Next-Generation Sequencing: Transforming Science...

Smart Biotech Scientist | The CMC and... ·

2024/06/06

Unlock the future of epigenetics and join us for an insightful conversation with Jonathon Hill as he delves into the groundbreaking world of next-generation sequencing (NGS) and its transformative impact on science and medicine. Jonathon Hill is the VP of Science and Technology and a co-founder of Wasatch BioLabs and Associate Professor of Cell Biology and Physiology at Brigham Young University.Discover how cutting-edge nanopore technology is overcoming the limitations of traditional methods ...

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16:46

59: Next-Generation Sequencing: Transforming Science...

Smart Biotech Scientist | The CMC and... ·

2024/06/04

Curious about the latest advancements in next-generation sequencing (NGS) and how they are revolutionizing science and medicine?In this episode, we delve into the cutting-edge developments of NGS with our expert guest, Jonathon Hill, VP of Science and Technology and a co-founder of Wasatch BioLabs and Associate Professor of Cell Biology and Physiology at Brigham Young University, who has been at the forefront of this transformative field.Key Takeaways:Discover how NGS is empowering scientists...

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19:08

58: Crafting a Solid CMC Strategy: Key Factors and...

Smart Biotech Scientist | The CMC and... ·

2024/05/30

Dive into the realm of biotech with our latest episode as we unravel the enigma of Quality by Design (QbD) with Matthias Müllner, CEO of & Co-Founder bespark*bio, a company empowering viral vector-based medicines.Discover how integrating QbD principles early in your development cycle can revolutionize your approach to producing safe, high-quality products consistently. From understanding critical quality attributes to designing robust manufacturing processes, we illuminate the transformat...

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17:14

57: Crafting a Solid CMC Strategy: Key Factors and...

Smart Biotech Scientist | The CMC and... ·

2024/05/28

Join us for an insightful episode as we dive into the world of bioprocess CMC development strategies with Matthias Müllner, CEO of & Co-Founder bespark*bio, a company empowering viral vector-based medicines.Matthias shares his wealth of knowledge on avoiding common pitfalls in developing robust Chemistry, Manufacturing, and Controls (CMC) strategies. He also emphasizes the critical elements that ensure your biotech product's success.Key Takeaways:Start Strong: Establishing a comprehensive...

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15:07

56: Cultivated Meat: A Promising Future or an...

Smart Biotech Scientist | The CMC and... ·

2024/05/23

Is cultivated meat the food of tomorrow or just a passing trend? In this episode, we dive deep with Steven Lang, an expert in the field of cultivated meat. Steven sheds light on the intricate process of creating meat in the lab, the challenges faced, and the potential future of this innovative industry.Key Takeaways:Precision in Analytics: Discover how cutting-edge sensory analytics are crucial for developing cultivated meat that mimics traditional meat's texture and taste.Regulatory Innovati...

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22:45

55: Cultivated Meat: A Promising Future or an...

Smart Biotech Scientist | The CMC and... ·

2024/05/21

How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process, changing the game rules with their ability to facilitate bubble-free gas exchange.Join us in this episode as we unravel the groundbreaking innovations in bioreactor technology with our guest, Patrick Bongartz, CEO of BioThrust and the visionary mind behind stress-free cell cultivation.Key Highli...

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19:19

54: Bionic Bioreactors: The Key to Stress-Free Cell...

Smart Biotech Scientist | The CMC and... ·

2024/05/16

How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process, changing the game rules with their ability to facilitate bubble-free gas exchange.Join us in this episode as we unravel the groundbreaking innovations in bioreactor technology with our guest, Patrick Bongartz, CEO of BioThrust and the visionary mind behind stress-free cell cultivation.Key Highli...

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18:20

53: Bionic Bioreactors: The Key to Stress-Free Cell...

Smart Biotech Scientist | The CMC and... ·

2024/05/14

How can you provide stress-free cultivation conditions to achieve higher cell concentrations and quality? In a nutshell, bionic bioreactors and thus change bubble-free gas exchange change the game.Join us as we delve into the future of biotech with our guest, Patrick Bongartz, CEO of BioThrust and an expert in innovative bioreactor design.Key Highlights:Unveil the groundbreaking "artificial lung," a marvel of engineering that decouples mixing and gas transfer, enabling stress-free cell growth...

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25:41

52: Unraveling the Complexity of Commercializing Cell...

Smart Biotech Scientist | The CMC and... ·

2024/05/09

Does the process of commercializing cell and gene therapies seem complex and unclear to you?Dive deep into the groundbreaking world of cell and gene therapies with our guest, Wajiha Ali, a strategy expert who believes in bridging the gap between research and commercialization with data, as we unravel the complexities of bringing life-saving therapies to patients.From cutting-edge technologies to innovative collaboration models, we explore the future landscape of these transformative treatment...

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19:26

51: Unraveling the Complexity of Commercializing Cell...

Smart Biotech Scientist | The CMC and... ·

2024/05/07

Are you finding the path to commercializing cell and gene therapies complex and uncertain?Join us as we explore this intricate landscape with our guest, Wajiha Ali. As a strategy expert who believes in bridging the gap between research and commericalization with data who she will guide us through the challenges, victories, and vital strategies for successfully bringing these cutting-edge therapies to market.Key Highlights:Discover the amplified complexity of cell and gene therapies, from pati...

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11:08

50: Decode Bioprocess Success: The Art of Stakeholder...

Smart Biotech Scientist | The CMC and... ·

2024/05/02

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17:10

49: Decode Bioprocess Success: The Art of Stakeholder...

Smart Biotech Scientist | The CMC and... ·

2024/04/30

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18:54

48: Mastering Process Economics: Driving Down Costs...

Smart Biotech Scientist | The CMC and... ·

2024/04/25

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16:55

47: Mastering Process Economics: Driving Down Costs...

Smart Biotech Scientist | The CMC and... ·

2024/04/23

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25:54

46: From Lab to Table: The Science Behind Cultivated...

Smart Biotech Scientist | The CMC and... ·

2024/04/18

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14:26

45: From Lab to Table: The Science Behind Cultivated...

Smart Biotech Scientist | The CMC and... ·

2024/04/16

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18:26

44: Mastering the Art and Science of Glycan...

Smart Biotech Scientist | The CMC and... ·

2024/04/11

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22:39

43: Mastering the Art and Science of Glycan...

Smart Biotech Scientist | The CMC and... ·

2024/04/09

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13:14

42: Revealing the Disciplined Pursuit of Less in...

Smart Biotech Scientist | The CMC and... ·

2024/04/04

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209 results

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