Day One®

54:00

The Psychedelic Resurgence: From Counterculture to...

Day One® ·

2026/08/26

One in three people will experience a mental health disorder in their lifetime, PTSD went more than 20 years without a new approved treatment, and spending keeps rising while outcomes keep getting worse. Against that backdrop, Australia has become the first country in the world where psychiatrists can prescribe MDMA and psilocybin.In this episode, host Emily Casey sits down with Dr Michael Winlo, Chief Scientific Officer at Emyria, the company behind the Empax network of psychedelic-assisted therapy

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42:48

The Buzzword That's Killing Your Pitch: Billy Chan on...

Day One® ·

2026/08/25

Pick My Brain is supported by our wonderful sponsors:Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, and get visas handled fast, so you stay focused on scaling. Deel takes care of onboarding, HR, IT, EOR, benefits, and compliance, so your team can grow without borders.It's why more than 40,000 fast-growing companies trust Deel to move fast.Visit https://www.deel.com/dayoneGalah Cyber offers Application Security Assessment.Get a clear, ten-minute

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21:18

Nobody Knows What to Pay Anymore: A Building Tech...

Day One® ·

2026/08/25

Eight guests into Building Tech Teams, one theme has shown up in every single episode: money. A principal software engineer who now manages a team of agents asks what he should be paid, and nobody in the room has a clean answer. AI has changed what one person can produce, and salaries have come off the rails behind it.In this best-of episode, James MacDonald pulls together the sharpest thinking on compensation from five of his first eight guests. Nathan Hill, Head of Telco at AWS, on the question

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58:16

We're afraid of the wrong thing in AI - with Paloma...

Day One® ·

2026/08/20

Paloma Newton is the founder of Elita, a longevity platform for dogs that combines biological testing, clinical history, and the changes owners notice day to day into one picture of how a dog is ageing. She built it backwards by most startup standards, a stem cell bank before a product, years of science before a single marketing push, all under one rule: don't promise more than the platform can back up.On this episode, Paloma brings that same rigor to two of the week's biggest AI headlines. She

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01:23:16

Building with atoms and bits: 5 Founders Making Hard...

Day One® ·

2026/08/19

Five founders. Building with atoms and bits. Right at the heart of Australia. From robots that scan the human body to robots watching over satellites in space, one goal unites them: making Australia a better place to start a business.Season 2 of Oversubscribed opens at BrewDog Everleigh in Sydney with Will Crowe of HEO, Joe Harris of Alloy, John Carroll of Vexev, Cibby Pulikkaseril of Zabidou, and Lachlan Bramble of Antares. Between them they're building satellites, robotic ultrasound machines,

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36:33

Why You Should Think Global From Day One: Ilana Elbaz...

Day One® ·

2026/08/18

Pick My Brain is supported by our wonderful sponsors:Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, and get visas handled fast, so you stay focused on scaling. Deel takes care of onboarding, HR, IT, EOR, benefits, and compliance, so your team can grow without borders.It's why more than 40,000 fast-growing companies trust Deel to move fast.Visit https://www.deel.com/dayoneEpisode SummaryIlana Elbaz joined Deel when it was five people, one developer and

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01:13:27

Why "The Number Is Never the Problem": Matt...

Day One® ·

2026/08/18

Most companies treat compensation as a math problem: get the number right and the rest takes care of itself. Matt McFarlane says that’s backwards, and it’s the reason so many pay conversations go sideways even when the number itself is fair.In this episode of Building Tech Teams, James MacDonald sits down with Matt McFarlane, founder of FNDN, the compensation consultancy he built after years running People Operations inside fast scaling startups. They get into why counteroffers rarely work, the

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01:05:24

Darius Monsef – You're the Number One Consumer of...

Day One® ·

2026/08/17

Want to partner with Life After Launch?Explore sponsorship and partnership opportunities at https://lifeafterlaunchpod.com/partner-with-usDarius Monsef has built a color-palette website that grew to millions of users, sold two companies, raised over $40 million for a pediatric healthcare startup, and shut it all down. Twice. He's brutally honest about why.Darius walks through how a joke website for rating color squares became a design resource used by Adobe, how wearing his own branded t-shirt got

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01:02:31

Benjamin Plummer (Dragonfly Intelligence) on AI's...

Day One® ·

2026/08/13

Benjamin Plummer has one of the stranger CVs in Australian tech: nine years inside Bridgewater Associates, the world's largest hedge fund, building an AI lab alongside IBM Watson's inventor, scaling a startup he says went from $10M to $160M in revenue in eighteen months as CEO, and now running Dragonfly Intelligence, a firm that buys ordinary services businesses and rebuilds them as AI-native companies from the ground up.This conversation starts with the week ChatGPT tried to cheat its way out of

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34:15

How Do You Grow a Marketplace When Both Sides Are...

Day One® ·

2026/08/11

Pick My Brain is supported by our wonderful sponsors:Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, and get visas handled fast, so you stay focused on scaling. Deel takes care of onboarding, HR, IT, EOR, benefits, and compliance, so your team can grow without borders.It's why more than 40,000 fast-growing companies trust Deel to move fast.Visit https://www.deel.com/dayoneGalah Cyber offers Application Security Assessment.Get a clear, ten-minute

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01:14:56

Why "Show Me Your Harness" Beats Any Coding Test:...

Day One® ·

2026/08/10

Most technical interviews still ask a candidate to write a function on a whiteboard. Adam Witanowski says that question is already obsolete, and what should replace it says everything about how AI is changing who gets hired.In this episode of Building Tech Teams, James MacDonald sits down with Adam Witanowski, AI Architect at nib, where he has spent the past several years building the insurer's AI engineering practice from the ground up. They get into why most enterprise AI projects underperform

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49:49

Kirstin Hunter – You're Spending 95% of Your Brain on...

Day One® ·

2026/08/10

Want to partner with Life After Launch?Explore sponsorship and partnership opportunities at https://lifeafterlaunchpod.com/partner-with-usKirstin Hunter has co-founded a super fund, run a startup accelerator, and now leads Australia's biggest crowdfunding platform. None of it was the plan.She grew up in Tweed Heads folding junk mail for two cents a letterbox, trained to be a doctor, then pivoted through law and consulting before a friend told her the pro bono work she loved was just "the trinkets"

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01:03:37

The Junior Engineer Isn't Needed Anymore: Cloë...

Day One® ·

2026/08/03

The junior engineer used to be the safe first hire. Cloë Stanbridge says AI just made that job disappear, and that's only the start of what's rewriting tech hiring right now.In this episode of Building Tech Teams, James MacDonald sits down with Cloë Stanbridge, Talent Lead at Airtree, one of Australia's most active venture capital firms. Cloë spends her days helping early-stage founders make their first engineering hires and helping later-stage companies scale their teams, work she's done from both

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50:39

Jodie Imam - Sometimes You Don't Need a Rocket Ship....

Day One® ·

2026/08/03

If you've ever felt like you're not a "real" founder because you're not chasing unicorn status, this episode is your permission slip to build differently.Jodie Imam has done almost everything you can do in the Australian startup ecosystem. She co-founded Occasional Butler and went head to head with Airtasker (who eventually acquired her), opened depo8, one of Melbourne's first coworking spaces, and now runs Tractor Ventures, the revenue-based funding company backing the founders who don't want to

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01:00:42

Eric Ries on What Investors Get Wrong About Governance

Day One® ·

2026/08/02

Episode SummaryEric Ries is the author of The Lean Startup and The Startup Way, and the founder of IMVU and the Long-Term Stock Exchange. His new book, Incorruptible, examines why companies drift from their mission once investors and boards take over, and what founders and early investors can do to prevent it.In this episode, Cheryl and Maxine unpack what Eric calls "financial gravity," the force that pulls companies toward extractive, value-destroying behavior even when everyone believes they're

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22:33

How Do You Sell Software to an Industry That Won't...

Day One® ·

2026/07/28

$320 billion flows through Australia's commercial construction industry every year — and far too much of it still moves on spreadsheets and re-keyed purchase orders. Mitchell Baker spent 12 years inside that machine as a contract administrator — on John Holland's $250M shopping-centre rebuild, and on Facebook's £150M London HQ with Kier — watching well-paid people burn their days copying data that already existed.So he built Claimstack, a workflow platform that follows the money from tender to final

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01:13:53

How to Build AI Capability Without Chasing Every New...

Day One® ·

2026/07/27

Most organisations are asking which AI model they should use. Patrick McQuaid thinks that is the wrong conversation.Patrick is Group Head of Data, Analytics & AI at NGM Group. He joins James MacDonald to explain how leaders can build practical AI capability without getting trapped by hype, vendor lock-in or an endless cycle of new tools.They discuss how NGM approaches AI inside a regulated banking environment, where privacy, risk and customer trust make it impossible to turn a weekend prototype

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47:43

Dom Pym – How To Build From Abundance, Even When You...

Day One® ·

2026/07/27

If you've ever talked yourself out of reaching out to someone because they're "too successful to reply," this episode will change how you send your next message.Dom Pym co-founded Up, one of Australia's fastest growing digital banks, and has personally invested $85 million into the Australian startup ecosystem. But he started with nothing. Dom tells Megan and Geo about growing up in a family that lost everything, and the "golden purse" his mum kept that somehow always had just enough in it, a lesson

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01:20

Introducing What The Health with Emily Casey |...

Day One® ·

2026/07/25

Five years of health innovation coverage, millions of reads, and a community of 11,000+.Now finally, What the Health has a podcast too — bringing the content to convos you can now listen to on the go and in video. Host Emily Casey brings the founders, clinicians, investors, operators, and policymakers shaping the future of health into the room for candid, useful, and occasionally unruly conversations.This trailer offers a first taste of the questions the show will tackle. What happens when billions

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01:20

Introducing What The Health with Emily Casey |...

Day One® ·

2026/07/24

Five years of health innovation coverage, millions of reads, and a community of 11,000+.Now finally, What the Health has a podcast too — bringing the content to convos you can now listen to on the go and in video. Host Emily Casey brings the founders, clinicians, investors, operators, and policymakers shaping the future of health into the room for candid, useful, and occasionally unruly conversations.This trailer offers a first taste of the questions the show will tackle. What happens when billions

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