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PODCAST

This Week in Virology

Vincent Racaniello

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

science life sciences

All Episodes

59:53

TWiV 1250: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/09/06

In his weekly clinical update, Dr. Griffin with Vincent Racaniello is shocked by COVID vaccine restrictions and uncertainties such as pharmacy stock, the ACIP meeting roster and whether it guidance is legal, 3 new ACIP members all anti-vaccine, ending of childhood vaccine mandates in Florida, the continued Legionnaire’s outbreak in Harlem, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns

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01:58:05

TWiV 1249: Demented and crAss

This Week in Virology ·

2025/08/31

TWiV reviews the major shakeup in CDC leadership, herpes simplex virus infection doubles the risk of dementia, and the prototypic crAssphage is a linear phage-plasmid. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV CDC director ousted? (CNN) Herpes simplex infection doubles risk of dementia (J Alzheimers Res) Fishing for viruses in senile

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47:07

TWiV 1248: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/08/30

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are dismayed about the recent attack on public health the firing of the director of the CDC as well as resignation of 3 others members of the agency’s leadership, the continued Legionnaire’s outbreak in Harlem, suspension of Ixchiq the Chikungunya virus attenuated infectious vaccine, the first US case of New World screwworm before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2

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01:52:48

TWiV 1243: Capitalism, COVID, and cancer

This Week in Virology ·

2025/08/10

TWiV discusses the latest worrisome Executive Order on oversight of federal grantmaking, RFK Jr winds down mRNA viral vaccine development, Lenacapavir, a drug for AIDS prevention and treatment, and how respiratory virus infections awaken dormant metastatic breast cancer cells in lungs. Hosts: Vincent Racaniello, Alan Dove, Rich Condit and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Oversight

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47:17

TWiV 1242: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/08/09

In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire’s outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be included

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01:57:12

TWiV 1241: The most beautiful experiment

This Week in Virology ·

2025/08/03

TWiV reports the administration putting a choke hold on billions of NIH health research funding, US Senators tell scientists they want to protect the NIH budget, then review a classic experiment showing the mechanism of DNA replication, and explain how jumbo phage DNA is transcribed in a membrane-bound compartment before transfer into proteinaceous “nucleus” compartment. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, Jolene Ramsey, and Angela Mingarelli Subscribe (free):

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48:05

TWiV 1240: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/08/02

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should be

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01:35:33

TWiV 1235: Two sexy to eradicate

This Week in Virology ·

2025/07/13

David Barton, Brian Kemp, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Guests: David Barton, Brian Kemp, and Olve Peersen Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Enterovirus C recombination groups (J Virol) Poliovirus polymerase L420 facilitates RNA recombination (J Virol)

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55:04

TWiV 1234: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/07/12

In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza

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01:54:51

TWiV 1231: What is a virus?

This Week in Virology ·

2025/06/29

TWiV discusses Sen. Cassidy calling for ACIP meeting delay, RFK Jr. abandons GAVI, millions of children at risk as global vaccination rates fall, RFK Jr. grilled by Congress, autism rates have increased 60-fold due to changed definitions, deep mutational scanning of rabies virus glyoprotein, and and proton gradient and incomplete TCA cycle in a giant virus. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become

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49:13

TWiV 1230: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/06/28

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are alarmed at how RFK is breaking his promise of not altering vaccine policies, and nonexistent data and studies are used by members of the ACIP to make changes to immunization practices in the absence of a CDC director, justification for not honoring the US commitment to GAVI and global public policies including support of routine childhood immunizations, placing millions of children at risk for the return of vaccine preventable

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01:23:18

TWiV 1229: Virology throughout Europe

This Week in Virology ·

2025/06/22

Rich travels to Dubrovnik for the European Congress of Virology 2025 and Vincent joins via Zoom to speak with Stéphane Blanc, Vanda Juranić Lisnić, and Elisabeth Puchhammer-Stöckl about their work on plant viruses, cytomegalovirus, and Epstein-Barr virus. Hosts: Vincent Racaniello and Rich Condit Guests: Stéphane Blanc, Vanda Juranić Lisnić, and Elisabeth Puchhammer-Stöckl Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at

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01:56:30

TWiV 1225: Poultry flu and SARS-CoV-2

This Week in Virology ·

2025/06/08

TWiV reviews the administration’s call for fools gold-standard science, NIH may publish in-house, avian influenza viruses in birds in China, and Omicron pathogenicity and immune responses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Fool’s Gold Standard Science (Nature) NIH may publish in-house (Stat News) Diversity of H9N2 in China (Nat

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55:48

TWiV 1224: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/06/07

In his weekly clinical update, Dr. Griffin with Vincent Racaniello in dismay examine the MAHA-Make America Health Again-report and its inclusion of fictious studies or “Creative literature degree Medical Science writing”, RFK Jr contradicted by the CDC for COVID-19 vaccine recommendations for children, reduction in MMR vaccine coverage, the ongoing bird flu and measles outbreaks, how the General Accounting Office instructed HHS to fix deficiencies in infectious disease testing before the next

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01:50:32

TWiV 1223: Someone is guano be sick

This Week in Virology ·

2025/06/01

TWiV reviews RFK Jr.”s MAGA report with non-existent literature citations, a new fungus that could further devastate North American bats, surveillance of avian influenza viruses through bird guano in remote regions, and the receptor for HKU5 coronaviruses is ACE2 from Pipistrellus abramus bats. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Bad

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01:05:16

TWiV 1222: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/05/31

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses vaccination trends, the changes COVID-19 vaccine recommendations for children and pregnant women, easing of vaccination exemptions in Texas, the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines and concern as confirmed diagnosis of COVID-19 rise

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54:19

TWiV 1220: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/05/24

In his weekly clinical update, Dr. Griffin with Vincent Racaniello debate the changes in FDA vaccine approval policy especially how it is applied to COVID-19 vaccines and restricts vaccine availability/usage and Novavax’s vaccine, mpox on surfaces and in the air, “bird flu”, the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, the high number of childhood

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02:01:42

TWiV 1215: What's the worst that could happen?

This Week in Virology ·

2025/05/04

TWiV reviews universal vaccine initiative at NIAID, shut down of the Integrated Research Facility at Ft. Detrick, modeling the reemergence of infectious diseases as vaccination rates drop, and bacterial outer membrane vesicles bound to bacteriophages modulate neutrophil responses to bacterial infection. Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025

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02:05:06

TWiV 1213: Secrets of HepB cccDNA

This Week in Virology ·

2025/04/27

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection. Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Committee of experts to counter vaccine misinformation (Science)

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37:32

TWiV 1202: Clinical update with Dr. Daniel Griffin

This Week in Virology ·

2025/03/22

In his weekly clinical update, Dr. Griffin and Vincent Racaniello rue about the unknowns of Sudan disease and new cases of paralytic polio, discuss the growing measles outbreak, exposure of newborns to measles, the FACTS about vaccination, high pathogenic influenza in dairy cows and cats, RFK’s statement “just let the virus rip through the hens” before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what

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