APS Publications Podcast

3:48

Interorgan Insights: Sprouting and splitting -...

APS Publications Podcast ·

2026/05/20

In this podcast, author Kuihua Zhan discusses the recently published article, ‘Vascularization Is Driven by Sprouting and Subsequent Splitting: Mechanisms of Physiological Angiogenesis in a Porous Biomaterial Scaffold and Intervention Insights’. The article describes engineering interventions to support the physiological vascularization of large-scale tissue scaffolds. Vascularization Is Driven by Sprouting and Subsequent Splitting: Mechanisms of Physiological Angiogenesis in a Porous Biomaterial

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4:58

Time-Restricted Feeding Improves Metabolic Rhythms...

APS Publications Podcast ·

2026/05/19

In this AI generated episode of The APS Publications Podcast featuring Function, we will dive into exciting new research that is shaping our understanding of how the body works at its most fundamental level. We spotlight the article “Short-term time-restricted feeding improves metabolic rhythms and liver mitochondrial bioenergetic function in high-fat diet-fed mice,” by Valcin et al. published recently in Function. Across the U.S. and the world, more people are developing fatty liver disease—now

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3:40

Interorgan Insights: Role of the gut microbiome in...

APS Publications Podcast ·

2026/05/15

In this podcast, author Arun Jose discusses the recently published article, ‘Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study.' The prospective cohort study linked the gut microbiome, gut-derived metabolites, and disease severity in patents with pulmonary arterial hypertension undergoing right heart catheterization. Authors found that the presence of Lactobacillus was associated with less severe disease. Lactobacillus Is Associated With Disease

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4:46

Interorgan Insights: MASLD through the lens of the...

APS Publications Podcast ·

2026/05/07

In this podcast, coauthors Gaurab Bhaduri and Anchin Kalia discuss their recently published review, ‘The Mitochondrial–Autophagy Axis in MASLD: Mechanisms, Crosstalk, and Therapeutic Targets’. The review integrates contemporary evidence regarding mitochondrial dysfunction and autophagic regulation in metabolic dysfunction–associated steatotic liver disease (MASLD). The Mitochondrial–Autophagy Axis in MASLD: Mechanisms, Crosstalk, and Therapeutic Targets Gaurab Bhaduri, Anchin Kalia, Banshi Saboo,

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4:57

Interorgan Insights: Highlighting the Crucial Role of...

APS Publications Podcast ·

2026/04/17

In this podcast, author Daniela Negrini discusses the recently published review, ‘The Thoracic Lymphatic Vasculature: Inter-Organ Strategies to Achieve an Optimal Tissue Function’. The article highlights the important but often overlooked role of vascular lymphatic system and the contribution of lymphatic vasculature to the control of extracellular fluid volume and composition as it applies to the majority of the body tissues. The Thoracic Lymphatic Vasculature: Inter-Organ Strategies to Achieve

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6:49

Exploring molecular shifts induced by pseudohypoxia...

APS Publications Podcast ·

2026/04/10

In this episode of The APS Publications Podcast, featuring AJP-Regulatory, Integrative and Comparative Medicine, author Laura Oller discusses her recent article, "Molecular shifts induced by pseudohypoxia in gray seal blubber: an ex vivo approach." This study explored how blubber regulates responses to chemically induced pseudohypoxia. This study showed a faster, but sustained, increase in molecular markers of hypoxia. It documents downstream molecular responses to those hypoxia-induced changes,

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5:37

Interorgan Insights: Unraveling the paradox of...

APS Publications Podcast ·

2026/04/02

In this podcast, Nguyen Duc Huy Hoang discusses his recently published article, ‘Mechanosensory Silence During Cardiac Stress’. He asks the question, "Why does mechanosensory stress in the heart so often remain perceptually silent?" and hopes his group's new conceptual gating framework, Cardiac Mechanoafferent Silencing Model, will shed some light on the topic and support the prioritization of future experimental and translational investigations.Mechanosensory Silence During Cardiac Stress Nguyen

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6:27

Interorgan Insights: Microcirculation as the...

APS Publications Podcast ·

2026/03/24

In this podcast, coauthors Yuan Li and Mingming Liu discuss their recently published article, ‘Functional segregation of pancreatic microcirculation reveals sex-dependent microhemodynamic signatures’. The article used a multi-scale approach to investigate pancreatic microhemodynamics in healthy male and female mice. Authors identified sexual dimorphism in pancreatic microhemodynamics that was restricted to the exocrine compartment, where blood vessels expressed different levels of CD31 and estrogen

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4:55

Interorgan Insights: Vagus nerve stimulation across...

APS Publications Podcast ·

2026/03/12

In this podcast, coauthors Yifeng Bu and Imanuel Lerman discuss their recently published review, ‘A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action’. The review overviews VNS mechanisms and their translational relevance, and thus serves as a foundational resource for advancing the science and clinical deployment of precision neuromodulation and bioelectronic medicine.A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and

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2:58

Interorgan Insights: Improving perimenopausal health...

APS Publications Podcast ·

2026/03/03

In this podcast, coauthors Yujie Xu, Han Wu, Ru Mu, Lu Yang, Yixuan Li, and Xian Ma discuss their recently published review, 'Kisspeptin Neurons as Integrative Hub: Cross-Talk of HPO–HPT–HPA Axes in Perimenopausal Reproductive Health’. The findings highlight the multi-axis pathophysiology of perimenopausal endocrine disorders and suggest therapeutic potential for treatments targeting kisspeptin neurons as part of individualized, multi-axis approaches.Kisspeptin Neurons as Integrative Hub:

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5:50

Interorgan Insights: Modulation of AQP1 and TGFB1 to...

APS Publications Podcast ·

2026/02/13

In this podcast, coauthors Chrysi Keskinidou and Nikolaos S. Lotsio discuss their recently published research article, ‘Disrupting BMP/TGF-β Signaling: Modulation of AQP1 and TGFB1 in Human Pulmonary Microvascular Endothelial Cells’. The article describes the authors' deep dive into the interactions between AQP1 and TGFB1 in human pulmonary vascular endothelial cells, and and provide a novel perspective on the interactions of the BMP/TGF-β signaling pathway. Disrupting BMP/TGF-β Signaling:

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6:01

Interorgan Insights: Insulin and the Secret to...

APS Publications Podcast ·

2026/02/06

In this podcast, corresponding author Yuan-Yuan Zhang discusses the recently published review, ‘Insulin as an Accelerator and Brake of Aging: From Molecular Landscape to Clinical Interventions’. Here, Dr. Zhang describes key findings, key takeaways, and key gaps that relate to our understanding of the role of insulin in aging and how it can be leveraged for anti-aging therapies. Listen here to learn why her and her co-authors argue that the secret to healthier aging lies with insulin and in helping

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9:10

Navigating the frontier of AI-assisted student...

APS Publications Podcast ·

2026/01/29

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthors Suzanne Estaphan, David Kramer, and Harry Witchel discuss their recently published article, “Navigating the frontier of AI-assisted student assignments: challenges, skills, and solutions.”This paper presents a framework to effectively design take-home assessments in the generative artificial intelligence (AI) era with four key recommendations to navigate the challenges and opportunities posed by

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7:41

The chick embryo model as an educational tool to...

APS Publications Podcast ·

2026/01/23

In this episode of the APS Publications Podcast, featuring an article from Advances in Physiology Education, authors Declan McLaughlin, Aisling Keane, and Joe Quinn discuss their recently published article, “The chick embryo model as an educational tool to explore the effect of alcohol on cardiovascular development.” This study explores the use of the chick embryo model as a teaching aid to illustrate connections between anatomy and physiology during development. Providing direct observation

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8:29

Associations between heart size and anthropometric...

APS Publications Podcast ·

2026/01/23

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthors Madyson Hintz and Aisya Ahmad Zamri discuss their recent article, “Associations between heart size and anthropometric and cardiovascular indicators: an undergraduate physiology teaching laboratory.” They share how a hands-on undergraduate lab lets students observe heart measurements with ultrasound, collect body and cardiovascular data, and explore how factors like age, sex, body size, and hand

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8:09

Jigsaw technique: will it help Gen Z nursing students?

APS Publications Podcast ·

2026/01/16

In this podcast, Dr. Rashmi Chandel discusses the recently published article, "Jigsaw technique: Will it help Gen Z nursing students?" This study examines the effectiveness of the jigsaw technique (JST) as a student-centered learning strategy for engaging Generation Z undergraduate nursing students. Recognizing Gen Z learners’ distinct cognitive styles and preferences, the research compares JST with conventional lectures across four physiology modules using a crossover design. Results showed

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7:21

Active learning to improve numeracy skills and...

APS Publications Podcast ·

2026/01/16

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Stephen Fitzjohn and Frances MacMillan discuss their recently published article, “Active learning to improve numeracy skills and confidence using quizzes in first-year biomedical science undergraduates.” They share how thoughtfully designed, gamified quizzes in Blackboard helped students practice numeracy skills, build confidence, and achieve significant improvement. The conversation highlights a practical

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7:29

From anonymity to engagement: the benefits of...

APS Publications Podcast ·

2026/01/09

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, James Davis discusses their recently published article, “From anonymity to engagement: the benefits of early-semester student-instructor meetings.”This study shows that brief, early-semester student-instructor meetings foster stronger connections, increase student participation, and improve self-reported academic performance in large lecture courses. The following article demonstrates how a simple, scalable

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5:20

Interorgan Insights: Pulmonary Vascular Endothelial...

APS Publications Podcast ·

2026/01/08

In this podcast, co-first author Jonathan Hyde discusses the recently published article, ‘Pulmonary Vascular Endothelial Dysfunction is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model’. The study used an in vivo large animal model combined with ex vivo and in vitro studies to investigate pulmonary vascular endothelial cell dysfunction associated with the Glenn procedure. The results suggest that low, non-pulsatile flow associated with Glenn physiology plays a pivotal

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4:45

Transcriptome-driven Health-status...

APS Publications Podcast ·

2026/01/07

In this episode of the APS Publications Podcast, Dr. Ralph Rühl discusses his team’s new article in Physiological Genomics, “Transcriptome-driven Health-status Transversal-predictor Analysis for health, food, microbiome and disease markers for understanding of lifestyle diseases.” The article outlines the development of a novel artificial intelligence approach based on machine-learning to predict general health and food-intake parameters. This novel technique, which is based on PBMC transcriptomics

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