PODCAST

AJP-Heart and Circulatory Physiology Podcast

American Physiological Society

Commentary and discussion on featured articles in AJP - Heart and Circulatory Physiology

science life sciences

All Episodes

46:04

Cardiac Sex Differences and COVID

AJP-Heart and Circulatory Physiology Podcast ·

2023/12/07

Given that there appears to be variation in significant risk to the cardiovascular system following SARS-CoV2 infection with regard to age and sex, the latest study by Rouhana et al. provides a foundation for studying sex differences with a preclinical model of infection to the direct exposure to SARS-CoV-2 and the impact on the myocardium of ferrets. Listen as Associate Editor Dr. Keith Brunt (Dalhousie University) interviews authors Dr. Alyson Kelvin (University of Saskatchewan) and Dr. Glen Pyle

28:13

Preload and Calcium Handling in Muscular Dystrophy

AJP-Heart and Circulatory Physiology Podcast ·

2023/11/28

What does a mouse heart have to do with an M&M candy (the regular kind, not the peanut variety)? In our latest episode, Associate Editor Dr. Crystal Ripplinger (University of California, Davis) interviews author Dr. Tim Domeier (University of Missouri) and expert Dr. DeWayne Townsend (University of Minnesota) about the recent study by Haffner et al et al. The authors examined cardiac calcium mishandling and damage in the setting of Duchenne muscular dystrophy (DMD). Using a genetic mouse model

20:49

Coronary Endothelial Function, HIV, and Aging

AJP-Heart and Circulatory Physiology Podcast ·

2023/11/08

People living with HIV have an increased risk of developing cardiovascular disease, including coronary artery disease. Until now, it has been unclear why. In this episode, Guest Editor Dr. Ashley Walker (University of Oregon) interviews author Dr. Efthymios Ziogos (Johns Hopkins Medicine) and expert Dr. Jennifer Williams (McMaster University) about the recent study by Ziogos et al. published in the Call for Papers Impact of Aging on CV System. Ziogos and co-authors used advanced MRI to assess

48:56

Estimating Cardiac Output During Incremental Exercise

AJP-Heart and Circulatory Physiology Podcast ·

2023/10/02

What does it sound like when a young researcher meets one of his science heroes for the first time? Listen to this episode of The AJP-Heart and Circ Podcast to find out. Associate Editor Dr. Keith Brunt (Dalhousie University) interviews author Dr. Holger Burchert (University of Basel) and leading expert Dr. William Stringer (Lundquist Institute at Harbor-UCLA Medical Center) about a new Methods and Resources article published by Burchert and Klimpel as part of the recent Call for Papers on

33:52

Hot Yoga and Sodium-Induced Endothelial Dysfunction

AJP-Heart and Circulatory Physiology Podcast ·

2023/08/10

Come for the yoga metaphors, stay for the science. In this episode, Associate Editor Dr. Keith Brunt (Dalhousie University) interviews author Dr. Stacy Hunter (Texas State University) and expert Dr. Annet Kirabo (Vanderbilt University) about the new study by Hunter et al., which examined the impact of hot yoga on sodium-induced pressor responses and endothelial function of Black women. In a randomized control trial that combined the thermal stress of hot yoga and a salt challenge, the authors

32:32

Soluble Prorenin Receptor and Vascular Damage

AJP-Heart and Circulatory Physiology Podcast ·

2023/07/31

What is the impact of female sex hormones on obesity, diabetes, and vascular dysfunction? In this episode, Deputy Editor Dr. Zam Kassiri (University of Alberta) interviews authors Dr. Bruna Visniauskas and Dr. Minolfa Prieto (both at Tulane University School of Medicine), along with expert Dr. Glen Pyle (IMPART Network at Dalhousie Medicine) about the new study by Visniauskas et al. Using a long-term high fat diet mouse model of type 2 diabetes, the authors found that male mice had higher increases

18:15

Pre-operative COVID19 and Cardiovascular Complications

AJP-Heart and Circulatory Physiology Podcast ·

2023/07/24

When is it safe to have surgery after COVID? Listen as Associate Editor Dr. Jason Carter (Baylor University) interviews lead author Dr. Anai Kothari (Medical College of Wisconsin) and leading expert Dr. Michael Joyner (Mayo Clinic) about the groundbreaking new research study by SenthilKumar et al. that evaluated how pre-operative COVID infection might affect a patient’s risk of post-operative major adverse cardiovascular and cerebrovascular events (MACE) by analyzing data from 457,804 patients

39:40

How the American Physiological Society can Promote...

AJP-Heart and Circulatory Physiology Podcast ·

2023/06/29

What does being a good ally look like? In a new Perspective, authors Dr. Karla Haack (Merck), Dr. Austin Robinson (Auburn University), Dr. Dexter Lee (Howard University College of Medicine), Dr. Keisa Mathis (University of North Texas Health Science Center), and Dr. Junie Paula Warrington (University of Mississippi Medical Center) discuss how the American Physiological Society (APS) can promote Black physiologists and support them in the challenges they face. The authors sat down with The AJP-Heart

41:04

Inclusive Demography in Medical Research

AJP-Heart and Circulatory Physiology Podcast ·

2023/06/27

How can researchers capture the most accurate demographic data possible on intake surveys for human participant studies? Listen as author and moderator Dr. Karla Haack (Merck) interviews co-authors Dr. Jesse Moreira (Boston University) and Dr. Troy Roepke (Rutgers, The State University of New Jersey) about their recent Perspective regarding how researchers can do inclusive and precise research with an open mindset in order to avoid excluding groups of people when developing survey demographic

29:07

Efficacy of Growth Hormone-Releasing Hormone-Agonist...

AJP-Heart and Circulatory Physiology Podcast ·

2023/05/19

Heart failure with preserved ejection fraction (HFpEF) is, in many ways, a fascinating tale of modern cardiovascular medicine that, according to lead author Dr. Joshua Hare (University of Miami Miller School of Medicine), has taught cardiovascular researchers and clinicians a lot of humility. Understanding HFpEF in a variety of animal models has led to a paradigm shift away from heart failure linked to low ejection fraction. In this episode Associate Editor Dr. Jonathan Kirk (Loyola University

21:18

LV Vortex Patterns Change from Newborns to Adults

AJP-Heart and Circulatory Physiology Podcast ·

2023/04/10

“You cannot make good predictions for patients until you understand the physiology,” stated Dr. Kristian Becker (Icahn School of Medicine at Mount Sinai). Becker and co-authors demonstrated for the first time echocardiographic evidence of a transition in the left ventricular vortex patterns of the heart from the newborn period to the adult period. Listen as Associate Editor Dr. Amanda LeBlanc (University of Louisville) interviews Dr. Becker and expert Dr. Ann Chiao (Oklahoma Medical Research

22:31

Anxiety and Muscle Sympathetic Nerve Activity

AJP-Heart and Circulatory Physiology Podcast ·

2023/03/29

While anxiety disorders are the most common mental health issue in the United States and are known to increase the risk of hypertension and cardiovascular disease, the links between anxiety, muscle sympathetic nerve activity and blood pressure have not been interrogated to date. Listen as host Dr. Megan Wenner (University of Delaware) interviews author Dr. Jeremy Bigalke (Montana State University) and expert Dr. Jody Greaney (The University of Texas at Arlington) about the latest research by

23:54

COVID-19 and Cardiac Autonomic Function

AJP-Heart and Circulatory Physiology Podcast ·

2023/02/28

What effects do COVID symptomology and time since diagnosis have on cardiac autonomic function? Listen as Guest Editor Dr. Tiago Peçanha (Manchester Metropolitan University) interviews first author Dr. Rachel Skow (The University of Texas at Arlington) and expert Dr. Chris Minson (University of Oregon) about the research by Skow et al, aimed at better understanding the mechanisms underlying increased cardiovascular risk associated with COVID infection. Skow and co-authors set out to study the

17:37

Estrogen and Human Arterioles

AJP-Heart and Circulatory Physiology Podcast ·

2023/02/10

What happens when your hypothesis is…wrong? Listen as host Dr. Dan Tyrrell (University of Michigan Medical School) interviews lead author Dr. Julie Freed (Medical College of Wisconsin) and content expert Dr. Chi Fung Lee (Oklahoma Medical Research Foundation) about the new Rapid Report by SenthilKumar et al., which investigated the function of estradiol on human microvessels. In contrast to their hypothesis, Freed and co-authors found that exogenous estradiol treatment of arterioles isolated from

20:49

Cell Therapy and Endothelial Dysfunction in HFpEF

AJP-Heart and Circulatory Physiology Podcast ·

2023/02/07

Is inflammation the driving force for diastolic dysfunction in heart failure with preserved ejection fraction (HFpEF)? In this episode, Deputy Editor Dr. Zamaneh Kassiri (University of Alberta) interviews author Dr. Thassio Mesquita (Cedars-Sinai Medical Center) and expert Dr. Darryl Davis (University of Ottawa Heart Institute) about the research by de Couto et al. Using a Dahl salt-sensitive rat model of HFpEF, the authors delivered cardiosphere-derived cells (CDCs) via intracoronary injection

30:03

Guidelines for Cardiac Electrophysiology

AJP-Heart and Circulatory Physiology Podcast ·

2022/12/22

The world of cardiac electrophysiology can be daunting, so we suggest that you listen to this insightful conversation with the experts. Deputy Editor Dr. Zamaneh Kassiri (University of Alberta) interviews authors Dr. Crystal Ripplinger (University of California Davis), Dr. Nikki Posnack (The George Washington University and Children's National Hospital), Dr. Alexey Glukhov (University of Wisconsin-Madison), Dr. Matthew Kay (The George Washington University), Dr. Carol Ann Remme (Amsterdam

25:46

Global Allogeneic Cardiosphere-Derived Cells in Acute MI

AJP-Heart and Circulatory Physiology Podcast ·

2022/12/15

Is a pre-treatment with low dose cyclosporine immunosuppression necessary to limit allogeneic cardiosphere-derived cell therapy rejection? Listen as Associate Editor Dr. Amanda LeBlanc (University of Louisville) interviews senior author Dr. John Canty (University of Buffalo) and expert Dr. Fabio Recchia (Scuola Superiore Sant'Anna; Temple University) about the latest study by Techiryan et al. In this blinded randomized controlled trial using swine, the authors tested whether low dose cyclosporine

14:15

Vascular Function During the Estrous Cycle

AJP-Heart and Circulatory Physiology Podcast ·

2022/11/17

When Dr. Ashley Walker (University of Oregon) began to study sex differences with vascular aging and cognitive decline, she and her team went to the literature for guidance on research study design to account for the confounding variable of estrous cycle in young female mice. Problem: There were no recommendations in the literature. Solution: The Walker Lab got to work. In our latest episode, Dr. Amanda LeBlanc (University of Louisville) interviews lead author Dr. Ashley Walker and first author Ms

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AJP-Heart and Circulatory Physiology Podcast

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