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PODCAST

PhageLine

Planomicrobium massiliensis

PhageLine unpacks the science of bacteriophages, one paper at a time. From groundbreaking studies to surprising discoveries, we translate complex research into engaging conversations. Whether you are steeped in microbiology or just discovering the fascinating world of phages, PhageLine delivers a unique perspective on the science behind these bacterial predators.PhageLine is on BlueSky. Follow us never to miss anything again.This podcast is generated using artificial intelligence. Infectious disease

science life sciences

All Episodes

18:10

PhageLine #12: Biofilm Models for Phage Therapy of...

PhageLine ·

2025/04/05

Hello and welcome to PhageLine - your line to everything phage.This week, we will focus on 3D models for mimicking biofilms in diabetic foot ulcers for phage therapy. German researchers from Frankfurt and Jena recently reviewed this topic. The phage lab at the University Hospital Frankfurt was recently featured in Capsid & Tail for having built its own phage laboratory from scratch under very challenging conditions. Have fun!

en-US

28:39

PhageLine #11: Adsorption Mechanisms

PhageLine ·

2025/03/29

Hello and welcome to PhageLine - your line to everything phage.This week, we will focus on the mechanisms of tailed bacteriophage adsorption. For that, we will discuss a review from Storms and Sauvageau from the Department of Chemical and Materials Engineering at the University of Alberta, which was published in Elsevier's "Virology" in 2015. Have fun!

en-US

30:52

PhageLine #10: Phage-Derived Endolysins in Food Safety

PhageLine ·

2025/03/22

Welcome to PhageLine. This week, we will focus on the applications of bacteriophage-derived endolysins for foodborne bacterial pathogens and food safety, a topic recently reviewed by Kahn et al. from Shenzhen University in Frontiers of Microbiology. Have fun!#medicine #biology #bacteriophages #infection #amr #basicresearch #food #foodsafety

en-US

16:30

PhageLine #9: Functional Genomics with CRISPRi-ART

PhageLine ·

2025/03/15

Welcome to PhageLine. This week, we will focus on CRISPRi-ART, a method for functional genomics of diverse bacteriophages published by Benjamin Adler et al. from the University of California in Nature Microbiology at the end of February. Have fun!#medicine #biology #bacteriophages #infection #amr #basicresearch #CRISPR #genomics #cas13

en-US

15:19

PhageLine #8: Synergy of Mucoactive Drugs and Phages

PhageLine ·

2025/03/08

Welcome to PhageLine. This week we will examine the synergistic action of mucoactive drugs and phages against Pseudomonas aeruginosa and Klebsiella pneumoniae. Have fun!#medicine #biology #bacteriophages #cough #amb #nac #infection #amr

en-US

18:35

PhageLine #7: The BREX Anti-Phage Immunity System

PhageLine ·

2025/03/01

Welcome to PhageLine. This week we will focus on the molecular basis of foreign DNA recognition by the BREX anti-phage immunity system. Have fun!This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode.#medicine #biology #bacteriophages #bacteria #defense #infection #amr

en-US

14:42

PhageLine #6: Phages and Nitric Oxide on Medical Devices

PhageLine ·

2025/02/22

Welcome to PhageLine. This week we will focus on a bacteriophage-based method for infection and thrombosis prevention using a phage-immobilized, nitric oxide-releasing surface. Have fun!This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode.#medicine #biology #bacteriophages #devices #engineering #thrombosis #infection #amr

en-US

16:24

PhageLine #5: The LNT103 engineered endolysin for...

PhageLine ·

2025/02/15

Welcome to PhageLine. This week we will focus on using specific phage proteins called endolysins instead of whole phages to fight bacteria by discussing the in vitro and in vivo efficacy of an engineered endolysin targeting Gram-negative pathogens. Have fun!This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode.

en-US

22:28

PhageLine #4: 100 Cases of Personalized Phage Therapy

PhageLine ·

2025/02/08

Welcome to PhageLine. In this week's episode, we will focus on one of the biggest phage papers in 2024: a multicentre, multinational, retrospective observational study of personalized bacteriophage therapy outcomes for 100 consecutive cases headed by Jean-Paul Pirnay and Sarah Djebara.This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode.

en-US

22:06

PhageLine #3: Bacteriophage-Based Biosensors

PhageLine ·

2025/02/01

Welcome to PhageLine. In this week's episode, we will discuss bacteriophage-based biosensor technology by discussing the review Bacteriophage-based biosensors technology: Materials, fabrications, efficiencies and shortcomings (Haq et al., 2025 Biotechnology Reports).This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode.

en-US

40:48

PhageLine #2: Phage Isolation and Characterization

PhageLine ·

2025/01/25

Welcome to PhageLine. In this week's episode, we will discuss the isolation and characterization of phages with clinical relevance from environmental sources.This week's papers are:Isolation of a lytic bacteriophage against extensively drug-resistant Acinetobacter baumannii infections and its dramatic effect in rat model of burn infection (Ghaznavi-Rad et al. 2022 JCLA)Isolation and characterization of a lytic bacteriophage against Pseudomonas aeruginosa (Sharma et al. 2021 Sci Rep)This

en-US

32:41

PhageLine #1: An Overview of Phage Therapy

PhageLine ·

2025/01/18

Hello and welcome to PhageLine - your line to everything phage.This podcast is where we discuss exciting research papers on bacteriophages once a week.To get started let's get a general overview of the topic by talking through a review by Kortright et al. from 2019 (last author Paul E. Turner), titled "Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria".This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents

en-US

32 results

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