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PODCAST

Dr. ヒディ研究室 - 科学をもっと身近に

【サイエンスをもっと身近に】をコンセプトとした、リベラルアーツ・ミニ講義中心の教育系コンテンツです。主に自然科学をトピックスとして扱っています。毎日6時更新！チャンネル登録よろしくお願いいたします。--- 運営者：Dr. ヒディ分子生物学者 Ph.D. ---

science life sciences

All Episodes

00:20:28

Vol.10 UPF1 Targets Identified via Direct...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/22

Vol.10 UPF1 Targets Identified via Direct Transcriptome Stability DeterminationTani H, Imamachi N, Salam KA, Mizutani R, Ijiri K, Irie T, Yada T, Suzuki Y, Akimitsu N. Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability. RNA Biol. 2012 Nov;9(11):1370-9. doi: 10.4161/rna.22360. Epub 2012 Oct 12. PMID: 23064114; PMCID: PMC3597577.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:12:39

Vol.9 GAS5 lncRNA regulation by RNA degradation pathway

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/15

GAS5 lncRNA regulation by RNA degradation pathwayTani H, Torimura M, Akimitsu N. The RNA degradation pathway regulates the function of GAS5 a non-coding RNA in mammalian cells. PLoS One. 2013;8(1):e55684. doi: 10.1371/journal.pone.0055684. Epub 2013 Jan 30. PMID: 23383264; PMCID: PMC3559549.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:17:06

Vol.8 LncRNAs - Indicators of chemical stress in stem...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/13

LncRNAs - Indicators of chemical stress in stem cells Tani H, Onuma Y, Ito Y, Torimura M. Long non-coding RNAs as surrogate indicators for chemical stress responses in human-induced pluripotent stem cells. PLoS One. 2014 Aug 29;9(8):e106282. doi: 10.1371/journal.pone.0106282. PMID: 25171338; PMCID: PMC4149554.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:13:36

Vol.7 LncRNAs - Chemical exposure indicators and gene...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/12

LncRNAs - Chemical exposure indicators and gene modulationTani H, Okuda S, Nakamura K, Aoki M, Umemura T. Short-lived long non-coding RNAs as surrogate indicators for chemical exposure and LINC00152 and MALAT1 modulate their neighboring genes. PLoS One. 2017 Jul 18;12(7):e0181628. doi: 10.1371/journal.pone.0181628. PMID: 28719640; PMCID: PMC5515456.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:13:48

Vol.6 Short-lived lncRNAs as chemical stress...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/11

Short-lived lncRNAs as chemical stress indicators in HepG2 cellsTani H, Numajiri A, Aoki M, Umemura T, Nakazato T. Short-lived long noncoding RNAs as surrogate indicators for chemical stress in HepG2 cells and their degradation by nuclear RNases. Sci Rep. 2019 Dec 30;9(1):20299. doi: 10.1038/s41598-019-56869-y. PMID: 31889167; PMCID: PMC6937343.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:22:53

Vol.5 Kcnq1ot1 and Rmst lncRNAs as biomarkers in...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/10

Kcnq1ot1 and Rmst lncRNAs as biomarkers in murine liver diseaseYokoyama S, Muto H, Honda T, Kurokawa Y, Ogawa H, Nakajima R, Kawashima H, Tani H. Identification of Two Long Noncoding RNAs, Kcnq1ot1 and Rmst, as Biomarkers in Chronic Liver Diseases in Mice. Int J Mol Sci. 2024 Aug 16;25(16):8927. doi: 10.3390/ijms25168927. PMID: 39201613; PMCID: PMC11354866.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:18:29

Vol.4 RMST long noncoding RNA - cancer and disease...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/03/09

Vol.4 RMST long noncoding RNA - cancer and disease InvolvementTani H. RMST: a long noncoding RNA involved in cancer and disease. J Biochem. 2025 Feb 5;177(2):73-78. doi: 10.1093/jb/mvae083. PMID: 39673327.Tani’s Homepage:https://www.hidenoritani.com/about-4

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00:15:40

Vol.3 Metabolic labeling of RNA evaluating synthesis...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/02/27

This episode explores the advancements in RNA biology, particularly focusing on the study of long noncoding RNAs (lncRNAs) and the methodologies used to analyze RNA synthesis and degradation rates. The attached file discusses the use of ribonucleoside analogs in metabolic labeling techniques, such as BRIC-Seq, SLAM-Seq, TUC-Seq, TimeLapse-Seq, and Dyrec-Seq, which have significantly enhanced our understanding of RNA dynamics.Paper：Anal. Sci. in

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00:18:21

Vol.2 The hidden directive of life - long noncoding RNA

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/02/21

This episode explores long noncoding RNAs (lncRNAs), a crucial area in molecular biology. It delves into the history and functions of lncRNAs, which play significant roles in gene regulation and cellular processes. The episode discusses technological advancements, such as next-generation sequencing, and highlights the potential of lncRNAs in medical applications, including cancer research. It also touches on future prospects and unresolved mysteries in the field, emphasizing the complexity and

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00:36:50

Vol. 1 Recent advances and prospects in RNA drug...

Dr. ヒディ研究室 - 科学をもっと身近に ·

2025/02/19

This episode focuses on RNA therapeutics. This revolutionary field has transformed medicine since the 1970s, offering new treatments for previously intractable diseases. From antisense oligonucleotides to mRNA vaccines, RNA therapeutics have shown remarkable potential. Key milestones include the discovery of RNA interference and the approval of treatments for spinal muscular atrophy and amyloidosis. The COVID-19 pandemic accelerated interest in mRNA vaccines, highlighting RNA's role in rapid

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30 results

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