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PODCAST

From Our Neurons to Yours

Wu Tsai Neurosciences Institute at Stanford University, Nicholas Weiler

This award-winning show from Stanford’s Wu Tsai Neurosciences Institute is a field manual for anyone who wants to understand their own brain and the new science reshaping how we learn, age, heal, and make sense of ourselves.Each episode, host Nicholas Weiler sits down with leading scientists to unpack big ideas from the frontiers of the field—brain-computer interfaces and AI language models; new therapies for depression, dementia, and stroke; the mysteries of perception and memory; even the debate

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All Episodes

39:25

Does good sleep insulate the brain against...

From Our Neurons to Yours ·

2025/03/06

We're kicking off our new season with a deep dive into one of neuroscience's most fascinating mysteries: sleep. This unconscious third of our lives isn't just about rest – it's absolutely critical for brain health, memory consolidation, and overall well-being. But here's where it gets intriguing: recent research suggests that increased napping as we age might be an early warning sign of Alzheimer's disease.To unpack this complex relationship, we're thrilled to

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40:46

How to live in a world without free will | Robert...

From Our Neurons to Yours ·

2024/12/05

Today, we are speaking with the one and only Robert Sapolsky, a Stanford neurobiologist, a MacArthur "Genius", and best-selling author of books exploring the nature of stress, social behavior, and — as he puts it — "the biology of the human predicament." In his latest book, Determined, Sapolsky assertively lays out his vision of a world without free will — a world where as much as we feel like we're making decisions, the reality is that our choices are completely determined by biological and ...

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35:10

The power of psychedelics meets the power of placebo:...

From Our Neurons to Yours ·

2024/11/21

Join us as we dive back into the world of psychedelic medicine with anesthesiologists Boris Heifets and Theresa Lii, who share intriguing new data that sheds light on how ketamine and placebo effects may interact in treating depression.We explore provocative questions like: How much of ketamine's antidepressant effect comes from the drug itself versus the excitement of being in a psychedelics trial? What do we know about how placebo actually works in the brain? And should we view the placebo ...

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21:52

Seeing sounds, tasting colors: the science of...

From Our Neurons to Yours ·

2024/11/07

Today, we are going back into the archives for one of my favorite episodes: We are talking to neuroscientist, entrepreneur, and best-selling author, David Eagleman. We're talking about synaesthesia — and if you don't know what that is, you're about to find out.Special NoteWe are beyond thrilled that From Our Neurons to Yours has won a 2024 Signal Award in the Science Podcast category. It's a big honor — thanks to everyone who voted!---Imagine Thursday. Does Thursday have a color

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38:31

The BRAIN Initiative: the national vision for the...

From Our Neurons to Yours ·

2024/10/24

Earlier this year, President Obama's signature BRAIN Initiative, which has powered advances in neuroscience for the past 10 years, had its budget slashed by 40%. Over the past decade, the BRAIN Initiative made roughly $4 billion in targeted investments in more than 1500 research projects across the country and has dramatically accelerated progress tackling fundamental challenges in neuroscience. As we head into the next federal budget cycle, the future of the initiative remains uncertain. Today

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37:33

The cannabinoids within: how marijuana hijacks an...

From Our Neurons to Yours ·

2024/10/10

Given the widespread legalization of cannabis for medical and recreational uses, you'd think we'd have a better understanding of how it works. But ask a neuroscientist exactly how cannabinoid compounds like THC and CBD alter our perceptions or lead to potential medical benefits, and you'll soon learn just how little we know.We know that these molecules hijack an ancient signaling system in the brain called the "endocannabinoid" system (translation: the "cannabinoids

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25:50

Memory Palaces: the science of mental time travel and...

From Our Neurons to Yours ·

2024/09/26

Today we are re-releasing an episode we did last year with Stanford neurobiologist Lisa Giocomo exploring the intersection of memory, navigation and the boundaries we create between ourselves and the world around us.This episode was inspired by the idea of memory palaces. The idea is simple: Take a place you're very familiar with, say the house you grew up in, and place information you want to remember in different locations within that space. When it's time to remember those things, you can ...

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25:48

Why new Alzheimer's drugs don't work | Mike Greicius,...

From Our Neurons to Yours ·

2024/09/12

In the past few years, Big Pharma has released not one, but three new treatments for Alzheimer’s disease. Aducanemab (2021), Lecanemab (2023), and Donanemab (2024), are the first treatments to effectively clear the brain of amyloid plaques — the sticky protein clumps whose build-up in the brain has defined the disease for decades. The problem? They may not help patients at all.Today’s guest, Stanford neurologist Mike Greicius, considers the new amyloid-clearing drugs a major disappointment — ...

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28:11

Depression's distinctive fingerprints in the brain |...

From Our Neurons to Yours ·

2024/08/29

Getting help for depression can be like purgatory. Setting aside for a moment the stigma and other barriers to seeking treatment in the first place, finding the right combination of medication and/or therapy can be a months- or years-long process of trial and error. And for about one third of people, nothing seems to work.Today we're talking with Dr. Leanne Williams, the founding director of the Stanford Center for Precision Mental Health and Wellness and Vincent V.C. Woo Professor in the Sta...

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21:27

How the brain helps cancers grow | Michelle Monje

From Our Neurons to Yours ·

2024/08/15

Today, we're talking with Stanford neuro-oncologist, Michelle Monje. This is actually the third time we've had Michelle on the show, in part because she's been a pioneer of three exciting frontiers in neuroscience — so far! This week, we're going to talk about cancer neuroscience. Michelle founded this new field with her discovery that deadly brain tumors not only link up physically with the healthy brain tissue surrounding them, but the cancers actually need the brain's

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30:31

Unraveling Timothy Syndrome: the new science of human...

From Our Neurons to Yours ·

2024/08/01

This week on From Our Neurons to Yours, we're talking about using new techniques for growing human brain tissue in the lab to solve a rare neurological disorder.Host Nicholas Weiler sits down with Sergiu Pasca an innovative Stanford scientist who has developed groundbreaking technologies to grow human brain tissue in the lab, creating "organoids" and "assembloids" that model brain disorders like autism and schizophrenia. Pasca describes the process of turning patient skin cells into embr...

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21:36

How VR could help treat depression with "radical...

From Our Neurons to Yours ·

2024/07/18

Today, we're going to talk about virtual reality and how it could be used to treat depression. We're talking with psychiatrist Kim Bullock, the founding director of Stanford's Neurobehavioral Clinic and Virtual Reality & Immersive Technologies (VRIT) program. Dr. Bullock — a physician certified in Neuropsychiatry, Psychiatry, and Lifestyle Medicine — calls herself a "radical behaviorist." Like other practitioners of cognitive behavioral therapy (CBT), she sees the

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23:35

Electronic skin and the future of wearable technology...

From Our Neurons to Yours ·

2024/07/04

The skin is full of contradictions. It’s soft and sensitive, but also tough and resilient, even self-healing. It’s both the barrier that protects us from infections and our most intimate connection with the outside world. Today’s guest, Zhenan Bao, has spent the last two decades reverse engineering the skin’s many remarkable properties in order to create wearable electronics that are just as soft, flexible, and versatile as the skin itself.Bao envisions a world where stick-on devices could help heal

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22:54

How a new kind of brain plasticity could help make...

From Our Neurons to Yours ·

2024/06/20

This week, we're diving into recent research that sheds light on a new form of brain plasticity involving changes in the insulation of nerve fibers — called myelin. It turns out that myelin plasticity is implicated in a number of serious conditions, from epilepsy to drug abuse and addiction.We're excited to bring back two previous guests on the show to share their insights on this previously unknown form of plasticity: Stanford psychiatry professor Rob Malenka (S1 E1 - Psychedelics and

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21:56

Our plastic brains: learning, memory and aging with...

From Our Neurons to Yours ·

2024/06/06

-- We're re-releasing our conversation with Carla Shatz, one of our favorites from the archive, which comes up all the time on the show in the context of brain plasticity and aging. Enjoy, and see you next time! -NW -- When we're kids, our brains are amazing at learning. We absorb information from the outside world with ease, and we can adapt to anything. But as we age, our brains become a little more fixed. Our brain circuits become a little less flexible. You may have heard of a concep...

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0:25

Programming Announcement

From Our Neurons to Yours ·

2024/05/30

Hi everyone — quick programming announcement. As we head into summer, we'll be moving to an every-other-week cadence as we prepare more conversations from the frontiers of neuroscience. I'm very excited about what we're working on for you, so stay tuned!In the meantime, we'd love to hear from you! Email us at neuronspodcast@stanford.edu with your thoughts, praise, critiques, or just to say hello. That's all for now. See you next time!Send us a text!Thanks for listening! If you're enjoyin...

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27:38

Neuroscience and AI: What artificial intelligence...

From Our Neurons to Yours ·

2024/05/23

The powerful new generation of AI tools that has come out over the past few years — DALL-E, ChatGPT, Claude, Gemini, and the rest — have blown away our old ideas about what AI can do and raised questions about what it means for computers to start acting... intelligent?This week, we ask what the rise of these systems might teach us about our own biological intelligence — and vice versa. What does modern neuroscience have to say about how AI could become as flexible, efficient, and resili...

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29:00

How we remember, why we forget | Anthony Wagner

From Our Neurons to Yours ·

2024/05/16

At some point in our lives, we all struggle with memory — learning a new name, remembering that book you were reading just yesterday or that word on the tip of your tongue. So what can neuroscience teach us about why we remember, why we forget, and how we might even improve our memories? To answer this question, I spoke with neuroscientist Anthony Wagner, a memory expert in Stanford's Department of Psychology.Learn MoreWagner lab websiteRecent lab publicationsAnthony's new book: Brain Science...

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23:36

Psychedelics Part 2: How do drugs alter our...

From Our Neurons to Yours ·

2024/05/09

Today, we're going to talk about how psychedelics alter our perception of reality and what that says about... reality! Welcome to part two of our conversation with Stanford anesthesiologist and psychedelics researcher Boris Heifets! Last time, we talked with Boris about the question of why psychedelics help people with mental health disorders. This week, we're going to dive into a different question, which is to explore how psychedelics work in the brain. How are they able to alter

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30:27

Psychedelics, placebo, and anesthetic dreams | Boris...

From Our Neurons to Yours ·

2024/05/02

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