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PODCAST

Global Neurology Academy

The Global Neurology Academy (GNA) series offers certified education modules and video interviews from leading MS experts from across the globe as they address topics such as induction therapy in relapsing-remitting multiple sclerosis; No Evidence of Disease Activity (NEDA) concept; how different agents used in MS management may be utilized in induction therapy; appreciation of how reductions in end-organ damage impact patient quality-of-life; mechanisms of action of the classical as well as

science & medicine medicine

All Episodes

00:00:00

Is Amyloid-Targeting Therapy Worth It?

Global Neurology Academy ·

2024/01/31

Host: Richard S. Isaacson, MD Guest: Pierre N. Tariot, MD Guest: Gayatri Devi, MD, MS, FAAN, FACP Alzheimer’s Disease (AD) has historically been a condition associated with more questions than answers. These questions are only increasing with the flurry of developmental activity in recent years, particularly the introduction of the first ever disease modifying therapies, as the clinical picture is dramatically changing each day. To help address rising challenges prompted by

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00:00:00

What Does ARIA Look Like Clinically?

Global Neurology Academy ·

2024/01/31

Host: Richard S. Isaacson, MD Guest: Pierre N. Tariot, MD Guest: Gayatri Devi, MD, MS, FAAN, FACP Alzheimer’s Disease (AD) has historically been a condition associated with more questions than answers. These questions are only increasing with the flurry of developmental activity in recent years, particularly the introduction of the first ever disease modifying therapies, as the clinical picture is dramatically changing each day. To help address rising challenges prompted by

en

00:00:00

What is the Role of APOE4 Testing in Alzheimer’s...

Global Neurology Academy ·

2024/01/31

Host: Richard S. Isaacson, MD Guest: Pierre N. Tariot, MD Guest: Gayatri Devi, MD, MS, FAAN, FACP Alzheimer’s Disease (AD) has historically been a condition associated with more questions than answers. These questions are only increasing with the flurry of developmental activity in recent years, particularly the introduction of the first ever disease modifying therapies, as the clinical picture is dramatically changing each day. To help address rising challenges prompted by

en

00:00:00

Which Biomarkers Do You Recommend to Confirm Amyloid...

Global Neurology Academy ·

2024/01/31

Host: Richard S. Isaacson, MD Guest: Pierre N. Tariot, MD Guest: Gayatri Devi, MD, MS, FAAN, FACP Alzheimer’s Disease (AD) has historically been a condition associated with more questions than answers. These questions are only increasing with the flurry of developmental activity in recent years, particularly the introduction of the first ever disease modifying therapies, as the clinical picture is dramatically changing each day. To help address rising challenges prompted by

en

00:00:00

What Are the Data Behind ATT?

Global Neurology Academy ·

2024/01/31

Host: Richard S. Isaacson, MD Guest: Pierre N. Tariot, MD Guest: Gayatri Devi, MD, MS, FAAN, FACP Alzheimer’s Disease (AD) has historically been a condition associated with more questions than answers. These questions are only increasing with the flurry of developmental activity in recent years, particularly the introduction of the first ever disease modifying therapies, as the clinical picture is dramatically changing each day. To help address rising challenges prompted by

en

00:00:00

How Much Should We Worry About Amyloid-Related...

Global Neurology Academy ·

2024/01/31

Host: Richard S. Isaacson, MD Guest: Pierre N. Tariot, MD Guest: Gayatri Devi, MD, MS, FAAN, FACP Alzheimer’s Disease (AD) has historically been a condition associated with more questions than answers. These questions are only increasing with the flurry of developmental activity in recent years, particularly the introduction of the first ever disease modifying therapies, as the clinical picture is dramatically changing each day. To help address rising challenges prompted by

en

00:00:00

Mind Matters: Psychiatric Comorbidity in the...

Global Neurology Academy ·

2023/11/09

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Anibal Chertcoff, MD According to a recent study, psychiatric conditions like depression, anxiety, bipolar disorder, and schizophrenia may be early indicators of multiple sclerosis (MS) years before symptoms appear, which could enable the early diagnosis and treatment of patients with MS. Joining Dr. Charles Turck to share key details and findings from this study is Dr. Anibal Chertcoff. Not only is Dr. Chertcoff the lead author of

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00:00:00

Improving the Early Detection of TK2d with Genetic...

Global Neurology Academy ·

2023/10/09

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Austin Larson, MD Thymidine kinase 2 deficiency (TK2d) is a rare, genetic condition with nonspecific symptoms that wouldn’t lead to a definitive etiological diagnosis, underscoring the important role genetic testing plays in diagnosing patients. Learn more about the common clinical manifestations of TK2d and the diagnostic process with Dr. Charles Turck and Dr. Austin Larson, Assistant Professor in the Section of Genetics and

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00:00:00

Cases in TK2d Care: Lessons Learned in Diagnosing and...

Global Neurology Academy ·

2023/10/09

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Bruce H. Cohen, MD, FAAN The diagnosis and management of the rare genetic disease thymidine kinase 2 deficiency (TK2d) can come with many challenges. So to help shed light on those challenges and key management strategies, Dr. Charles Turck speaks with Dr. Bruce Cohen about his experiences and approaches to real-world patient cases in TK2d care. Dr. Cohen is the Chair of the NeuroDevelopmental Science Center at Akron Children’s

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00:00:00

Mitochondrial Matters: A Clinician’s Insights on...

Global Neurology Academy ·

2023/09/29

Guest: Bruce H. Cohen, MD, FAAN Thymidine kinase 2 deficiency is a very rare disorder that presents several diagnostic and treatment challenges. Learn more about those challenges along with the clinical manifestations of thymidine kinase 2 deficiency and the importance of taking a multidisciplinary approach to care with Dr. Bruce H. Cohen, Chair of the NeuroDevelopmental Science Center at Akron Children’s Hospital.

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00:00:00

Diagnosing Suspected MS: A Review of the Updated...

Global Neurology Academy ·

2023/09/01

Host: Andrew Wilner, MD, FACP, FAAN Guest: Eoin Flanagan, MB, BCh For the first time since 2008, the International Advisory Committee on Clinical Trials in Multiple Sclerosis have made updates to their diagnostic guidelines for patients with suspected multiple sclerosis (MS). Joining Dr. Andrew Wilner to discuss these key updates is Dr. Eoin Flanagan, the Chair of the Division of Multiple Sclerosis and Autoimmune Neurology at the Mayo Clinic in Rochester, Minnesota.

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00:00:00

Understanding the Fine Print: The Who, When, And What...

Global Neurology Academy ·

2023/07/27

Host: James Galvin, MD, MPH, FANA Guest: Jon Toledo, MD, PhD Recently, Alzheimer’s Disease (AD) saw its first approvals for disease modifying therapy (DMT). With amyloid-beta (Aβ) targeting DMT now a reality, the entire way this condition is viewed and managed is changing. In particular, amyloid-related imaging abnormalities (ARIA), the most common adverse effects seen in DMT trials, are unique to this agent class, raising new questions and considerations across multiple medical

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00:00:00

New and Emerging Therapies for Complex Epileptic...

Global Neurology Academy ·

2023/06/30

Host: Elaine C. Wirrell, M.D. Guest: Joseph E. Sullivan, MD This Expert Exchange webcast is designed to enhance clinicians’ awareness of emerging pharmacotherapies that demonstrate promise in optimizing seizure burden in patients with Lennox-Gastaut and Dravet syndromes.

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00:00:00

The Future of Muscular Dystrophy Management: Updates...

Global Neurology Academy ·

2023/06/29

Host: Jennifer Caudle, DO Guest: John F. Brandsema, MD Guest: Vamshi K. Rao, MD Limb-girdle dystrophy (LGMD) is a group of inherited neuromuscular diseases with at least 34 variants, all affecting muscles of the limb-girdle region. Because LGMD is so variable, it can be hard to detect and there are no FDA-approved treatments currently. Advances in gene transfer therapy have been slow to emerge. However, helping clinicians detect LGMD and know the next best steps is critical to

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00:00:00

The Future of Muscular Dystrophy Management: Updates...

Global Neurology Academy ·

2023/06/27

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Julie Parsons, MD Guest: Craig Zaidman, MD Duchenne Muscular Dystrophy, or DMD, is considered a rare disease, affecting 1 in 3,500 boy births. But to the patients afflicted-and to the families who love them-it is a painful, everyday experience. Current advances in gene transfer therapy are exciting. Helping clinicians interpret and utilize the outcomes of gene therapy clinical trials is critical to effective treatment

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00:00:00

Novel Investigational Treatment Options for Rett...

Global Neurology Academy ·

2023/05/26

Host: Jeffrey L. Neul, MD, PhD Guest: Alan K. Percy, MD Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to

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00:00:00

New Hope: Novel and Emerging Treatment Options for...

Global Neurology Academy ·

2023/05/26

Guest: Jeffrey L. Neul, MD, PhD Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT

en

00:00:00

Case Study: Diagnosis, Treatment, and Management of...

Global Neurology Academy ·

2023/05/26

Guest: Alan K. Percy, MD Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes

en

00:00:00

Case Study: Relatively Late Diagnosis & Management of...

Global Neurology Academy ·

2023/05/26

Guest: Jeffrey L. Neul, MD, PhD Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT

en

00:00:00

Living With Rett Syndrome: What to Expect at Each Stage

Global Neurology Academy ·

2023/05/26

Host: Alan K. Percy, MD Guest: Jeffrey L. Neul, MD, PhD Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to

en

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