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PODCAST

Your Brain On

Drs. Ayesha and Dean Sherzai

A podcast about the neuroscience of everything. From neurologists, researchers, and public health advocates Drs. Ayesha and Dean Sherzai, explore every aspect of our world through a neuroscientific lens, with science-based stories, interviews, anecdotes, and brain health facts. Equip yourself with neurologically sound answers to life"s everyday health questions and learn the essentials of brain health and optimization, one topic at a time.

science

All Episodes

48:38

Your Brain On... Social Media

Your Brain On ·

2025/01/15

Two decades on from the start of the smartphone revolution, we have the first humans who, for as long as they’ve been alive, have had the entire internet just a few taps away. What has this done to our brains? It’s been an unprecedented period of rapid change, and, with the largest social networking sites using every neurological trick in the book to keep us endlessly scrolling down our feeds, what can we do to make our relationship with social media healthier? In this episode of ‘Your Brain On...’,

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51:10

Your Brain On... (Sherzai Family Holiday Special)

Your Brain On ·

2024/12/25

Our incredible kids Sophia and Alex Sherzai join us for a special end-of-year episode of the ‘Your Brain On...’ episode! As a family of neuroscientists — Sophia in biomedical engineering, Alex in artificial intelligence, Ayesha in vascular neurology, and Dean in behavioral neurology — we have fascinating discussions (and debates) about all aspects of life and brain health almost every day. To close out the first year of the ‘Your Brain On...’ podcast, we’re bringing that energy to the show! We

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49:57

Your Brain On... Ketogenic Diets

Your Brain On ·

2024/12/18

High in fats and low in carbs, ketogenic diets were originally developed in the 1920s to treat children with epilepsy. Now, they’ve gained popularity for weight loss, and even improved cognitive function. But how much truth is there in the purported brain health benefits we see on social media? In this episode of ‘Your Brain On...’, we separate the facts from the fads, and discuss: • What one might eat on a typical ketogenic diet • How ketogenic diets affect brain metabolism • The different ways

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46:57

Your Brain On... ALS

Your Brain On ·

2024/12/11

ALS, a nervous system disease, ruled the headlines in the summer of 2014 thanks to the viral Ice Bucket Challenge. How has our knowledge of the disorder evolved a decade later? Amyotrophic lateral sclerosis, also known as ‘Lou Gehrig's disease’ (named after the iconic baseball player), is a progressive neurological disorder which breaks down a person’s motor neurons. The main symptoms are muscle weakness and impaired physical function — mild, at first, but in the latter stages of the disease’s

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44:45

Your Brain On... Ketamine

Your Brain On ·

2024/12/04

For decades, ketamine has mainly been used as an anaesthetic, but in more recent years, it’s gained popularity in mental health treatment. Conversations around the benefits and risks associated with its therapeutic usage ignited towards the end of 2023, when actor Matthew Perry, star of the sitcom ‘Friends’, died from the acute effects of the ketamine he was using to treat anxiety. In this episode of ‘Your Brain On...’, we discuss: • The neurochemical mechanisms of ketamine, and its interplay with

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01:08:36

Your Brain On... Sex

Your Brain On ·

2024/11/20

From the first spark of attraction, all the way to climax, sex sets off chemical fireworks in your brain. And yet, this beautiful, powerful act has become mired in shame and stigma. But through open conversation and deeper scientific understanding, we can cast off those shackles, and even embrace sex as a marker for cognitive and overall health. In this episode of ‘Your Brain On...’ — our Season 4 debut! — we discuss: • The neurological processes involved with sex, arousal, attraction, and desire •

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56:49

Your Brain On... Protein

Your Brain On ·

2024/10/17

Protein — how much do we need? What’s the healthiest way to consume it? Can we get enough from plant-based diets? Until recent decades, protein hasn’t been quite as prominent in public health discussions as sugar and fats. However, with longer lifespans emphasizing the importance of protein for long-term health, and growing confusion around the quality and quantity of protein needed, it has become a highly debated macronutrient. In ‘Your Brain On… Protein’, we explore: • The brain health benefits

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01:04:58

Your Brain On... Misinformation

Your Brain On ·

2024/10/09

The digital age has made it easier than ever to access health information, but how can we know which sources to trust? Social media is saturated with misinformation. Some of it is inadvertent — many bold pseudoscientific claims seem very convincing, and anyone could be forgiven for sharing it with the best intentions. But, a more deliberate manipulation of scientific information has become commonplace, often used to push certain narratives or turn a profit. Combating this misinformation machine can

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01:05:06

Your Brain On: A Brain Health Revolution Summit Special

Your Brain On ·

2024/10/02

20 incredible conversations with leading scientists, in one hour. We’re excited to present this special installment of Your Brain On, featuring highlights from some of the speakers talking at our first ever Brain Health Revolution Summit. Our first summit, running September 30 through October 6 2024, features seven days of hour-long discussions with the scientists who are actually conducting the studies, publishing the papers, and pushing public health policy reforms that are shaping our world. No

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55:45

Your Brain On... Having A Pet

Your Brain On ·

2024/09/25

What are our animal companions thinking? And how does our friendship with them change their brains, and our brains? We all wish we could communicate with our pets. Though we may never share a language, modern neuroscience has enabled us to ethically understand the cognitive anatomy and emotional signals of other animals like never before. In this episode of ‘Your Brain On...’, we discuss what we’ve learned so far, including: • The neurological phenomena that leads to domestication and, in turn,

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41:34

Your Brain On... Coffee

Your Brain On ·

2024/09/18

What does the most-purchased beverage in the world — coffee — do to your brain? Five centuries after its discovery, coffee is deeply entrenched in our diets on a global scale. More than half the U.S. population drinks coffee daily. We wake up with coffee, and catch up with friends over coffee. Historically, coffee has been heralded as an inspiring muse. But many headlines have warned us about the adverse effects of coffee. Is there truth in the supposed risks, or can we keep sipping away without a

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51:07

Your Brain On... Grief

Your Brain On ·

2024/09/11

What grief does to our brains, and how we can grow from one of life’s most challenging experiences. The impact grief has on your mind can be so severe, some experts refer to it as an ‘emotional traumatic brain injury’. And, like many life-altering physical changes, the cognitive effects of grief aren’t so much something to ‘get over’ — rather, they’re something we can learn to live with and thrive alongside. In ‘Your Brain On... Grief’, we discuss: • How the emotional trauma of losing those you love

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40:48

Your Brain On... Caregiving

Your Brain On ·

2024/09/04

As populations have aged, our need for caregivers has risen fast. The stresses of caregiving present brain health concerns that we must address urgently. Caregivers are heroes. But they’re often so focused on looking after someone else, they neglect themselves. And self-care is so vital for caregivers, because the role is one of the most physically-, emotionally-, and psychologically-demanding responsibilities anyone can take on. Here, we discuss what that self-care can look like. In this episode of

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59:43

Your Brain On... Meditation

Your Brain On ·

2024/08/28

Meditation: an ancient practice with brain health benefits proven by modern science. Whether you’re focusing on your breathing to quieten peripheral distractions or using mindfulness to rebalance your emotional reactivity to everyday stresses, practicing meditation can spark long-term neuroplastic changes that will help you feel more attentive and calm in everything you do. In ‘Your Brain On... Meditation’, we explore: • How meditation alters your brain chemistry and ‘retrains’ your broader nervous

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33:48

Your Brain On... Leg Strength

Your Brain On ·

2024/08/21

Leg strength isn’t just about physical health. There are enormous benefits for brain health, too. From the more obvious benefits for balance and mobility to the deeper neurochemical machinery that powers the production and transportation of brain-boosting proteins, leg strength has a far greater influence on brain health than we might expect. In this episode of ‘Your Brain On...’, we discuss: • The prevalence of injuries caused by falls in elderly populations (and how leg strength can help counter

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46:06

Your Brain On... Marijuana

Your Brain On ·

2024/08/14

The neuroscience behind the benefits and risks of marijuana, explained. Splintered legislature, evolving taboos, and new forms of consumption have created a fragmented market for cannabis, and made it challenging for scientists to research its effects on our brains and bodies. In this episode, we unpack what we know about the cognitive impacts of marijuana use — the good and the bad — and explore new studies which are filling in the gaps. We discuss: • The difference between the THC and CBD

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01:13:05

Your Brain On... Parkinson’s

Your Brain On ·

2024/08/07

From 18th century London to the promise of a global cure: the 200-year history of Parkinson’s disease. Parkinson’s, a neurodegenerative disorder most commonly characterized by tremors and other motor symptoms, is so complex, many medical professionals are starting to classify it as a group of diseases, rather than a single disease. In this episode, we explain those complexities, including: • The motor symptoms (e.g. cogwheel rigidity, bradykinesia) and non-motor symptoms (e.g. depression, sleep

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33:45

Your Brain On... Ozempic

Your Brain On ·

2024/07/03

Ozempic. Developed as diabetes medication. Adopted as a weight loss drug. Eyed for its potential neuroprotective effects. Hollywood’s popularization of Ozempic as a way to lose weight has made it one of the most widely-discussed drugs of our time, and has put immense stress on supply chains, sometimes preventing its intended users — type-2 diabetics — from accessing the medication. In this episode, we wade through the history, benefits, side-effects, neuroscience, and future of Ozempic, with the

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48:01

Your Brain On... Retirement

Your Brain On ·

2024/06/26

Retirement, often considered a period of late-life decline, can actually be a time of cognitive growth and prosperity. When we retire, all the neurologically stimulating aspects of our working life — the mental and physical challenges, socializing and strategizing with colleagues, etc. — can disappear overnight. An abrupt lifestyle change of this magnitude can be taxing for our brains, but with the right preparation, our twilight years can truly be the best of our lives. In this episode of ‘Your

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36:03

Your Brain On... Introversion

Your Brain On ·

2024/06/19

Do introverts/extroverts have different brains? Are you born introverted? Is introversion neurologically harmful? The definition of introversion has been blurred in the social media age. We all know introverts are more likely to enjoy alone time, and may find social settings more challenging, but what’s less clear is: why? And is introversion the same as social anxiety? In this episode, we discuss: • How common introverted traits can be observed in the brain • The nature vs. nurture debate of

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59 results

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