Proteomics in Proximity

List of names and affiliations mentioned in the UK Biobank context: Mark McCarthy (Genentech), Slavé Petrovski (AstraZeneca), Chris Whelan (Johnson and Johnson), Erin Smith (Takeda Pharmaceuticals), Melissa Miller (Pfizer), Ben Sun (Biogen).The ASHG announcement, honoring Sir Peter Donnelly, CEO of Genomics plc and Emeritus Professor of Statistical Science at the University of Oxford with the William Allan Award. A list of the many abstracts and plenary presentations at ASHG 2022 that

One of the first publications using Olink technology came out by Enroth S and Gyllensten U et al. Nature Communications 2014 “Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs”. Link to the paper is here: DOI:10.1038/ncomms5684To access the Olink Insight platform for protein biomarker data discovery free-of-charge with an email address, click here: https://insight.olink.com And be sure to check out the Publication Explorer!A recent

The 2022 Science Advances paper, “Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods” by Daniel H Katz and Rob Gerszten et al. is available online here.A highly informative Twitter thread by the first author Dr. Daniel Katz reviewing the figures of the paper is available here.If you are interested in learning more about the use of proteomics in multiomic strategies, here’s link to the Olink website where

Show Notes for PiP Ep 02 “Empower Genomics with Proteomics”For more information about the UK Biobank, an Olink to Science blog post called “Genetic Regulation of the Human Plasma Proteome in the UK Biobank” is available here. The preprint publication itself is available here on bioRxiv. If you’d like to see a great 15 minute presentation on what the goals are for the UK Biobank Pharma Proteomics Project, Dr. Chris Whelan (Biogen) presented this YouTube video at one of the UK Biobank’s

In case you would like to learn more about our backgrounds, Cindy’s LinkedIn is here, Sarantis’ is here, and Dale’s is here.For more information about the UK Biobank, an Olink to Science blog post called “Genetic Regulation of the Human Plasma Proteome in the UK Biobank” is available here. The preprint publication itself is available here on bioRxiv. If you’d like to see a great 15 minute presentation on what the goals are for the UK Biobank Pharma Proteomics Project, Dr. Chris Whelan

Co-hosts Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas from Olink Proteomics talk about the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. In case you were wondering, "in Proximity" refers to Olink's underpinning technology called the Proximity Extension Assay, to allow highly multiplexed protein analysis from small sample volumes for