The Lead Podcast presented by Heart Rhythm Society

33:19

The Lead Episode 151: Heart Rhythm 2026 Late-Breaker...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/21

This late-breaking sub-analysis from the CHAMPION-AF trial evaluated outcomes of left atrial appendage closure (LAAC) with the WATCHMAN FLX device versus oral anticoagulation in patients with atrial fibrillation who had previously undergone catheter ablation. Investigators found that LAAC provided similar protection against stroke, cardiovascular death, and systemic embolism compared with non-vitamin K oral anticoagulants (NOACs), while significantly reducing non-procedural bleeding events,

en

16:27

The Lead Episode 148: HRS 2026 Late-Breaker Coverage,...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/14

Join Digital Education Committee member Jason T. Jacobson, MD, FHRS, and his guests John L. Sapp, Jr., MD, FHRS and Kyoko Soejima, MD for this conversation at Heart Rhythm 2026 in Chicago. This discussion reviews the late-breaking clinical trial Ventricular Intramyocardial Navigation and Tachycardia Ablation Guided by Electrograms (VINTAGE): First-in-Human Experience with a Novel Therapy for Refractory Ventricular Arrhythmia, presented at HRS 2026 in Chicago. Faculty discuss the novel VINTAGE

en

15:23

The Lead Episode 149: Heart Rhythm 2026 Late-Breaker...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/14

Welcome to the latest episode of late-breaker coverage from Heart Rhythm 2026 in Chicago, with host Deep Chandh Raja, MBBS, MD, PhD, FHRS and his guests Paul Chun Yih Lim, MBBS, FHRS and Abhishek Deshmukh, MD. This discussion reviews the late-breaking HRS 2026 trial Safety and Performance of a Novel ICD Lead for Left Bundle Branch Area Pacing: Results from the ASCEND CSP Trial Arrhythmia, which evaluated a novel implantable cardioverter-defibrillator (ICD) lead designed specifically for left bundle

en

18:18

The Lead Episode 150: Heart Rhythm 2026 Late-Breaker...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/14

This discussion reviews the late-breaking HRS 2026 study Total Fatal Adverse Events Following Atrial Fibrillation Ablation Reported in an FDA Mandatory Reporting System: A Matter of Concern? The TiFFANY Study, which examined fatal adverse event reports associated with atrial fibrillation ablation using data from the FDA MAUDE database. Faculty discuss the incidence and mechanisms of rare but serious complications across ablation technologies, including pulsed field ablation and thermal energy

en

15:32

The Lead Episode 147: Heart Rhythm 2026 Late Breaker...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/07

Welcome to the third in this week's series of Lead episodes covering late breaking clinical trials from Heart Rhythm 2026 in Chicago. Join host Michael Lloyd, MD, FHRS, and his guests Christopher Kowalewski, MD and Karin Benali, MD, PhD for this discussion. This first-in-human, prospective study presented at Heart Rhythm 2026 evaluated noninvasive proton beam cardiac radioablation for patients with refractory ventricular tachycardia who had failed prior ablation and medical therapy. In a small,

en

14:50

The Lead Episode 145: Heart Rhythm 2026 Late Breaker...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/07

Welcome to the first episode in this week's triple-header of late-breaking clinical trial coverage from Heart Rhythm 2026 in Chicago. In this episode Melissa E. Middeldorp, MPH, PhD from the Digital Education Committee sits down with David H. Birnie, MD and T. Jared Bunch, MD, FHRS to talk through this exciting late breaker. This late-breaking substudy of the ALONE-AF trial presented at Heart Rhythm 2026 evaluated whether discontinuing oral anticoagulation (OAC) after successful atrial fibrillation

en

22:46

The Lead Episode 146: Late Breaker Coverage: A...

The Lead Podcast presented by Heart Rhythm Society ·

2026/05/07

Welcome to the second episode this week in our triple header of late breaking clinical trials coverage from Heart Rhythm 2026 in Chicago. Host Christopher C Cheung, MD, MPH, FHRS is joined by Mihail G. Chelu, MD, PhD, FHRS and Derek Chew, MD, MS, FHRS for a conversation in Chicago. The LEAP2 trial, a first-in-human chronic feasibility study presented at Heart Rhythm 2026, evaluated a novel leadless pacemaker designed for conduction system pacing to more closely replicate physiologic cardiac

en

A Message from The Lead Podcast Team for the Week of...

The Lead Podcast presented by Heart Rhythm Society ·

2026/04/20

Greetings from The Lead Podcast team! This week we are in Chicago at Heart Rhythm 2026. We are on-site and in-person, recording episodes from the conference, with a special focus on late-breaking clinical trials. We're very exited to share these with you! For this reason, there will not be a Lead episode released the week of April 20. Please join us the week of April 27 for our next, cutting-edge episode. We hope to see you in Chicago!

en

24:52

The Lead Episode 144: A Discussion of Enhanced...

The Lead Podcast presented by Heart Rhythm Society ·

2026/04/16

Join host Melissa Middeldorp and her guests Marco Perez and Kristie Coleman for this installment of The Lead! This multicenter randomized controlled trial evaluated whether smartwatch-based rhythm monitoring improves detection of previously undiagnosed atrial fibrillation (AF) in cardiology outpatients aged ≥65 years with elevated stroke risk. A total of 437 participants were randomized to either 6-month monitoring with an Apple Watch integrating photoplethysmography-based irregular rhythm

en

20:31

The Lead Episode 143: A Discussion of The Empirical...

The Lead Podcast presented by Heart Rhythm Society ·

2026/04/09

In this discussion, Dr. Deep Chandh Raja, MBBS, MD, PhD, is joined by Dr. Chi Keong Ching, MBBS, FHRS, and Dr. Haris M. Haqqani, MD, PhD, FHRS, to review the growing empirical evidence supporting anatomically guided ablation strategies for idiopathic left ventricular (LV) summit ventricular arrhythmias. The panel highlights how integrating multimodality mapping with a nuanced understanding of the region's complex anatomy can improve procedural success and safety. They also emphasize the role of

en

24:21

The Lead Episode 142: A Discussion of Class 1c...

The Lead Podcast presented by Heart Rhythm Society ·

2026/04/02

Join an expert-led discussion exploring the safety and clinical outcomes of Class 1c antiarrhythmic therapy following percutaneous coronary intervention (PCI) in patients with new-onset atrial fibrillation, based on insights from a nationwide cohort study. Deep Chandh Raja, MBBS, MD, PhD (Australian National University and Kauvery Hospital) hosts a dynamic conversation with Sandeep Gautam, MD, MPH, FHRS (University of Missouri Health) and Deepak Padmanabhan, MD, FHRS (Narayana Institute of Cardiac

en

The Lead the Week of Marh 23

The Lead Podcast presented by Heart Rhythm Society ·

2026/03/23

Hello everyone! The Lead will be going dark the week of March 23, but we will be back with more leading edge episodes in electrophysiology the week of March 30.

en

20:22

The Lead Episode 141: A Discussion of Impact of GLP-1...

The Lead Podcast presented by Heart Rhythm Society ·

2026/03/19

Join Digital Education Committee member and podcast host Melissa E. Middeldorp, MPH, PhD, along with this week's guest contributors,Sheldon Litwin, MD from the Medical University of South Carolina and Abhishek Deshmuckh, MBBS from the Mayo Clinic for this week's episode. This real-world retrospective cohort study evaluated whether glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy is associated with improved outcomes after atrial fibrillation (AF) ablation in obese patients using a large

en

20:56

The Lead Episode 140: A Discussion of Atrial...

The Lead Podcast presented by Heart Rhythm Society ·

2026/03/12

Join Digital Education Committee member and podcast host Melissa E. Middeldorp, MPH, PhD, along with this week's guest contributors, Joshua Silverstein MD, FHRS from Allegheny Health Network and Jonathan Ariyaratnam, BChir, MA, MB, CCDS, CEPS-A from the University of Adelaidefor this week's episode. This study by Vad and colleagues examined markers of atrial cardiomyopathy (AtCM) in 26,467 UK Biobank participants without prior atrial fibrillation (AF), heart failure (HF), or stroke, integrating

en

30:00

The Lead Episode 139: A Discussion of Improving...

The Lead Podcast presented by Heart Rhythm Society ·

2026/03/05

Join Digital Education Committee member and podcast host Melissa E. Middeldorp, MPH, PhD, along with this week's guest contributors, Nino Isakadze, MD, MHS, and Geraldine A. Lee, PhD, FESC for this week's episode. The POP-AF trial was a prospective, randomized controlled study evaluating whether a nurse-led, integrated lifestyle intervention before AF ablation improves outcomes. A total of 145 patients with symptomatic paroxysmal or persistent AF and at least one modifiable risk factor were

en

28:22

The Lead Episode 138: A Discussion of Safety,...

The Lead Podcast presented by Heart Rhythm Society ·

2026/02/26

Join Digital Education Committee member and podcast host Deep Chandh Raja, MBBS, MD, PhD, along with this week's guest contributors, Senthil Thambidorai, MD, FHRS and Lee Karl Thien, MD, CCDS for this week's episode. This real-world registry study evaluated the safety, feasibility, and mid-term outcomes of pulsed field ablation (PFA) for cavotricuspid isthmus (CTI)–dependent atrial flutter. Acute bidirectional CTI block was achieved in nearly all patients, with a low complication rate and high

en

23:02

The Lead Episode 137: A Discussion of Impact of...

The Lead Podcast presented by Heart Rhythm Society ·

2026/02/19

Join Digital Education Committee Vice-Chair and podcast host Tina Baykaner, MD, MPH, along with this week's guest contributors, Jackson J. Liang, DO and Edward P. Gerstenfeld, MD, MS, FHRS for this week's episode. This study evaluates the relationship between hospital ventricular tachycardia (VT) ablation volume and post-procedural complications, examining whether institutional procedural experience influences patient outcomes. The authors analyze complication rates across centers with varying VT

en

22:17

The Lead Episode 136: A Discussion of...

The Lead Podcast presented by Heart Rhythm Society ·

2026/02/12

Join Digital Education Committee Member and podcast host Jason T. Jacobson, MD, FHRS, along with this week's guest contributors, Gaurav A. Upadhyay, MD, FHRS and Pugazhendhi Vijayaraman, MD, FHRS for this exciting conversation! This Heart Rhythm Journal article explores the electrophysiologic signatures that occur during left bundle branch pacing (LBBP) as lead position changes, with a focus on identifying "uninterrupted transition" patterns in recorded electrograms. The findings help clarify how

en

25:33

The Lead Episode 135: A Discussion of Mechanical...

The Lead Podcast presented by Heart Rhythm Society ·

2026/02/05

Welcome to this week's episode of The Lead. Join HRS Digital Education Committee member and podcast host Danesh Kella, MBBS, FHRS as he welcomes his guests Rahul N Doshi, MD, FHRS and Robert D Schaller, DO, FHRS. They are discussing Mechanical Vacuum Aspiration and Debulking of Large Vegetations During Cardiac Implantable Electronic Device Extractions, which was published in the Journal of the American College of Cardiology in October 2025. This article describes the use of mechanical vacuum

en

22:45

The Lead Episode 134: A Discussion of Bachmann Bundle...

The Lead Podcast presented by Heart Rhythm Society ·

2026/01/29

Join Digital Education Committee Member and podcast host Deep Chandh Raja, MBBS, MD, PhD , and his guests Georgios Leventopoulos, MD, and Muthiah Subramanian, MD, CCDS, CEPS-A, for this week's Lead episode. This Heart Rhythm article investigates the Bachmann bundle as a target for pacing by using retrograde electrical mapping and correlating findings with underlying myocardial microstructure. The piece provides detailed insights into how Bachmann bundle activation pathways relate to tissue

en

All Episodes

Similar Podcasts

Edutainment Learning

Ralph Krauss

Daily Facts

Amalia Dupray and Montgomery Jones.

Les dents et dodo

BFMTV

Education Futures

Svenia Busson & Laurent Jolie

Out In The Hall

NHSA