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PODCAST

Into the Impossible With Brian Keating

Big Bang Productions Inc.

Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think

science natural sciences

All Episodes

51:14

Could Biological Robots Heal Us from the Inside? |...

Into the Impossible With Brian Keating ·

2025/10/28

Get started with 1 month free of Superhuman today, using my link: https://try.sprh.mn/briankeating What if cells from your own trachea sitting in a petri dish right now, could spontaneously organize into swimming robots that heal brain tissue? What if frog skin cells with no genetic modification whatsoever, could build copies of themselves from spare parts lying around? This isn't science fiction. This is the work of Michael Levin at Tufts University and is completely rewriting the rules of

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40:55

Did We Detect Dark Matter… or Fool Ourselves?

Into the Impossible With Brian Keating ·

2025/10/21

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥What if 85% of the universe is invisible—and the one experiment claiming to have found it is wrong? For nearly three decades, Italian physicists have claimed their DAMA/LIBRA experiment detected the elusive particles that make up dark matter—the mysterious substance holding galaxies together. Yet no one else has ever confirmed it. Join Brian Keating, UCSD cosmologist and host of The INTO THE IMPOSSIBLE

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72:52

Will this NEW Scientific Breakthrough Make Us Immune...

Into the Impossible With Brian Keating ·

2025/10/17

Get started with 1 month free of Superhuman today, using my link: https://try.sprh.mn/briankeatingToday's guest made bacteria immune to every virus that exists. This breakthrough could revolutionize medicine by creating virus proof cell therapies and potentially extending this protection to human cells. Also demonstrating that we can fundamentally rewrite the language of life itself, something that was previously thought impossible. George Church is a Harvard Medical School genetics professor

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62:22

Does Avi Loeb Have PROOF of Alien Technology?

Into the Impossible With Brian Keating ·

2025/10/12

➡️ WIN A METEORITE:https://briankeating.com/list— Once again, I had the pleasure of speaking to one of the most famous and perhaps the most controversial astrophysicists in the world – Avi Loeb! For those of you who don't know him, Avi is a professor of science at Harvard University, theoretical physicist, astrophysicist, and cosmologist. He is also a bestselling author and a dear friend of mine. By the time you see this, Avi will have published his new book, Interstellar: The Search for

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16:42

Brian Keating on Humility, Chutzpah, and the Arrow of...

Into the Impossible With Brian Keating ·

2025/10/10

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥Brian Keating and James Altucher have an unfiltered talk on humility, arrogance, and the strange mix of traits needed to achieve great things. From the wisdom of the Talmud to the Dunning–Kruger effect, they explore why even Nobel Prize winners wrestle with imposter syndrome. James shares how writing books requires a mix of blind confidence and humility, while Brian connects scientific resilience to

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50:19

Chris Hadfield’s Final Orbit! The Moon Landing Hoax,...

Into the Impossible With Brian Keating ·

2025/10/09

Boost your productivity 🧠 Start your 30-day free trial of Todoist today: https://get.todoist.io/q8k9tr 📝Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 Astronaut and bestselling author Chris Hadfield joins me to discuss his new Cold War thriller Final Orbit and the real history behind it—UAPs, Operation Paperclip, and the exiled genius who built China’s rocket program. Along the way, we debate the moon landing hoax, the cost of the ISS, and why

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53:33

From Pipe Bombs to Viagra: Nobel Prize Winner’s...

Into the Impossible With Brian Keating ·

2025/10/06

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥Lou Ignarro went from building pipe bombs as a curious teen to winning the Nobel Prize for discovering how a gas—nitric oxide—regulates blood flow, fuels Viagra, and revolutionized cardiovascular medicine. In this explosive conversation, we trace how one molecule transformed sex, science, and the story of human health. Key Takeaways: 00:00 Intro 00:55 The molecule that saves and kills 04:00 The

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116:52

EXCLUSIVE: Avi Loeb Reveals: What HiRISE Just Saw on...

Into the Impossible With Brian Keating ·

2025/10/04

Harvard astrophysicist Avi Loeb joins Brian Keating to discuss a groundbreaking observation: the HiRISE camera on NASA’s Mars Reconnaissance Orbiter has imaged 3I/ATLAS, a rare interstellar visitor, from the vantage point of Mars.In this episode, we explore: • What HiRISE detected and why it matters for planetary science. • How interstellar objects like ʻOumuamua and 3I/ATLAS challenge our theories. • Why Mars may become an ideal outpost for detecting future interstellar visitors. • The

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72:39

Is AI Our PARTNER or Our ENEMY? Google CTO Blaise...

Into the Impossible With Brian Keating ·

2025/09/30

Get started with 1 month free of Superhuman today, using my link: https://try.sprh.mn/briankeating Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 Is AI our partner in evolution, or is it a harbinger of our downfall? In this episode of Into the Impossible, I sit down with two brilliant minds to explore the current and future relationship between artificial intelligence, human evolution, and creativity. Blaise Agüera y Arcas, a leading AI researcher, and

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20:48

The Scientists: Lord Kelvin’s Dangerous Idea...

Into the Impossible With Brian Keating ·

2025/09/28

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 Dive into the fascinating world of Lord Kelvin, a pivotal figure in the scientific revolution! In this video, we explore his groundbreaking contributions, including the concept of absolute zero and the Kelvin temperature scale. oin my mailing list here 👉 briankeating.com/yt to win a meteorite! 💥 Timestamps: 00:00- Introduction to Lord Kelvin 02:15- The significance of absolute zero 05:30-

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50:59

Steven Pinker on Cancel Culture, Common Knowledge & AI

Into the Impossible With Brian Keating ·

2025/09/24

Get 3 months off the annual plan and start learning faster at shortform.com/impossibleIn this episode, Steven Pinker unpacks how common knowledge shapes everything from why rational people can’t agree to disagree to why markets boom and bust. We explore the risks of falsifying expert claims, the power of social norms, and whether civilization is held together by truths—or by the fictions we all agree to share. — Key Takeaways: 00:00 Intro 00:58 When common knowledge is wrong 02:37 The

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88:45

What Really Happened on the Moon?

Into the Impossible With Brian Keating ·

2025/09/22

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 Brian Keating sits in the guest chair on Julian Dorey's podcast. This fascinating conversation dives deep into the heart of science, skepticism, and the culture wars swirling around them. Together, Brian and Julian tackle everything from wild theories about NASA, the South Pole, and the moon landing, to the challenges of scientific gatekeeping, the allure of conspiracy thinking, and the importance—and

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72:12

How to Focus Like a Nobel Prize Winner | The James...

Into the Impossible With Brian Keating ·

2025/09/17

James sits down once again with cosmologist Brian Keating—longtime friend of the show and author of Into the Impossible: Focus Like a Nobel Prize Winner. In this candid conversation, they challenge each other’s views on focus, curiosity, and the trade-offs of staying in your lane. Brian shares behind-the-scenes lessons from interviewing Nobel Prize winners, the thinking behind his new “Keating Test” for AI, and why communication matters as much as discovery in science.This episode isn’t about

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80:05

Are We Wrong About the Big Bang? Niayesh Afshordi

Into the Impossible With Brian Keating ·

2025/09/16

Get Dr. Brian Keating’s NEW Book for Only 0.99! This week only: https://www.amazon.com/dp/B0FN8DH6SX?ref_=pe_93986420_775043100For over a century, cosmologists have believed that the universe began a single fiery moment. The Big Bang. But what if that story is incomplete? Or what if it's even wrong? My guest today, Professor Niayesh Afshordi, is a professor of astrophysics at the Perimeter Institute and the University of Waterloo. He and his colleague Bill Halpern argue that the real battle

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75:14

The Matrix Is a Documentary: Riz Virk on the...

Into the Impossible With Brian Keating ·

2025/09/14

Get my new book Focus Like a Nobel Prize Winner for just 99 cents while the sale lasts: https://a.co/d/hi50U9U Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 What if your life wasn’t real—not metaphorically, but literally? That’s the premise my guest today has been exploring for years. Rizwan Virk, MIT graduate, gaming entrepreneur, and author of The Simulation Hypothesis, believes that physics, computing, and even ancient wisdom traditions point to the

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48:46

The Man Who Named the Big Bang… and Hated It! Fred Hoyle

Into the Impossible With Brian Keating ·

2025/09/13

Buy my new book Focus Like a Nobel Prize Winner for just 99 cents for a limited time only https://a.co/d/hi50U9U Join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 Fred Hoyle coined the term “Big Bang”—but he hated the theory it described. Instead, he championed the steady state universe, helped uncover the stellar origin of the elements, and gave us the immortal phrase: “We are stardust.” This video explores Hoyle’s brilliance and contradictions: Why he mocked the

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32:54

David Deutsch Round 2: We Will Build Humans Before AGI

Into the Impossible With Brian Keating ·

2025/09/11

Get My New Book, Focus Like a Nobel Prize Winner, for Only $ 0.99! This week only: https://a.co/d/hi50U9U David Deutsch offers his insights into the physics that will impact our future, challenging our new technologies, such as AGI and the development of synthetic humans, as depicted in movies. Join us for this fascinating discussion as we go INTO THE IMPOSSIBLE. KEY TAKEAWAYS 00:00:00 – 00:00:39 Could machines experience thoughts and sensations like humans? 00:00:45 – 00:01:46 Deutsch argues

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98:16

Is 3I/ATLAS Alien Technolgy? Avi Loeb & MIchael...

Into the Impossible With Brian Keating ·

2025/09/09

Get my My new book, Focus Like a Nobel Prize Winner -- https://a.co/d/hi50U9U It's just 99¢ on Kindle for launch week ONLY. It’s the perfect companion to this conversation—lessons in thinking clearly, staying curious, and pushing past conventional wisdom from my conversations with 22 Nobel Prize winners! Brian Keating sits down with Harvard astrophysicist Avi Loeb and renowned skeptic Michael Shermer to dissect the latest enigma sweeping through our solar system—3I/ATLAS. • What makes

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50:23

Thomas Hertog: What Came Before The Big Bang?

Into the Impossible With Brian Keating ·

2025/09/06

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 In a sweeping conversation drawn from his collaboration with Stephen Hawking, Thomas Hertog explores the radical “no-boundary” theory—a vision of the cosmos with no singular beginning, evolving laws of physics, and a past that isn’t fixed until observed. Rejecting the untestable multiverse, Hertog and Hawking built a fully quantum cosmology that embeds the observer within the equations, predicting inflation and

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63:33

Ben Shapiro: Free Will, AGI, and the Scavengers...

Into the Impossible With Brian Keating ·

2025/09/02

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 We talk with Ben Shapiro about his new book “Lions and Scavengers” and how we each have a lion and a scavenger inside of us. Today’s society is shaped by lions who build great things, while the scavengers try to tear them down. ----------------------------------------------------------------------------------------- Additional resources: Ben Shapiro’s NEW Book Lions and Scavengers:

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