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PODCAST

Daily Value

Dr. William Wallace

Daily Value brings science out of the lab and into daily life. Hosted by Dr. William Wallace, each short, research-driven episode explores how nutrients, supplements, and metabolism influence how we think, move, and age. It’s evidence-based, concise, and designed to make you smarter about what fuels you.

health & fitness alternative health

All Episodes

18:03

The Neuroscience of Dietary Fiber

Daily Value ·

2025/07/31

In this episode of Daily Value, we look at the surprising connection between dietary fiber and cognitive health. Fiber isn’t just about digestion - it’s a powerful nutrient influencing your brain through the gut-brain axis. We’ll take a look at new research that reveals how optimal fiber intake may physically enhance and/or help maintain the structure of specific brain regions, important for memory and learning. Learn about the different types of fiber, their unique roles, and practical tips ...

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11:25

Optimizing Vitamin Uptake via the Microbiome

Daily Value ·

2025/07/01

In this episode of Daily Value, we evaluate the often-overlooked yet powerful connection between your gut microbiome and vitamin absorption. Going beyond basic nutrition, we’ll break down how gut bacteria directly influence your body's ability to synthesize and efficiently absorb essential vitamins through mechanisms such as transporter protein modulation, enzyme stimulation, and immune regulation. Practical and actionable insights are provided foster optimal gut health and nutritional status...

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19:24

Methylene Blue and the Bioenergetics of Memory

Daily Value ·

2025/06/24

In this episode of Daily Value, we look at the neurometabolic potential of methylene blue, a synthetic dye first synthesized in the 19th century, for supporting brain energy metabolism during aging. Originally developed for textile use, methylene blue has since demonstrated potential use as a redox-active agent in neuroprotection and memory enhancement (and how exactly it performs these actions). We look at it’s unique biochemical mechanism as an alternative electron carrier within the mitoch...

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20:46

The Vitamin C-risis: Why Current Guidelines Fail Us

Daily Value ·

2025/06/19

Today’s episode of Daily Value questions something fundamental—the guidelines that shape our daily vitamin C intake. What if the rules you've been following were set too low, missing a hidden metabolic reality that affects millions? New evidence suggests that current recommendations may underestimate our true biological needs—impacting energy, immune health, and even cognitive clarity. This episode will explore how subtle differences in absorption, cellular retention, and even the form of vit...

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10:06

The Vitamin Link to Neuropsychiatric Disorders

Daily Value ·

2025/06/06

In this episode of Daily Value, we look at the influence of B vitamins on mental health and neuropsychiatric disorders. The discussion is centered around a recently published meta-analysis suggesting a causal link between B vitamin deficiencies and the development of conditions such as Parkinson's disease, schizophrenia, and Alzheimer's disease. Talking points include the distinct impacts of vitamins B12, B6, and B9 (folate) on brain health, their role in one-carbon metabolism, and findings f...

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11:21

Gut Check: The Hidden Role of B Vitamins

Daily Value ·

2025/06/04

In this episode of Daily Value, we look into the research on the relationship between B group vitamins and the human gut microbiome. The discussion focuses on how B vitamins might act as prebiotics, influencing gut health and overall well-being. Talking points include how B vitamins interact with gut bacteria, their potential indirect benefits through cross-feeding, and the controversies around their absorption. 00:00 Introduction to B Group Vitamins and Gut Microbiome 01:14 Understandi...

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14:22

The Antioxidant of Antioxidants: A Compound You're...

Daily Value ·

2025/06/02

In this episode of Daily Value, we look at the often overlooked yet potent nutrient, alpha lipoic acid, which is integral to mitochondrial energy metabolism and cellular health. Discovered in 1937, ALA acts as a primary antioxidant in the body. This episode covers the distinction(s) between supplemental and endogenous ALA. The latter is able to cross the blood-brain barrier and is used therapeutically for conditions like diabetic neuropathy, oxidative stress, and metal detoxification. I will ...

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10:06

Energy Drink Ingredient Linked to Cancer? The Taurine...

Daily Value ·

2025/05/30

In this episode of Daily Value, we look at the recent controversy surrounding taurine and its alleged role in accelerating leukemia (cancer) growth. We take a look at the science behind the recent sensationalist headlines generated by well-known mainstream media outlets, based on a study by the Wilmot Cancer Institute using animal and cell models, which suggested taurine might fuel leukemia progression. We clarify the context of this research, contrasting it with taurine's established safety ...

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12:45

B12: When Normal Isn't Enough

Daily Value ·

2025/05/28

In this episode of Daily Value, we look at recent research suggesting that the B12 levels we’ve always accepted as "normal" might silently be failing our brains. New data reveals that standard B12 thresholds may not adequately shield us from subtle neurological decline. Are current diagnostics overlooking hidden deficiencies? We go into how B12 truly supports your nervous system, the overlooked significance of active B12, and why traditional treatments might need reconsideration, particularly...

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8:24

The Nutrient Duo That Could Save Your Mind

Daily Value ·

2025/05/26

In this episode of Daily Value, we look into the synergistic relationship between two nutrient classes in supporting brain health and mitigating cognitive decline. Drawing on evidence from past clinical evidence suggesting these two nutrient classes work in tandem to support brain function and health. Discussion Points: -Homocysteine’s role in disrupting fatty acid incorporation into cell membranes and amyloid-beta clearance. -Findings from one study, where some 70-year-old participants exper...

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13:48

NAD Wars: NMN vs NR in the Aging Battle

Daily Value ·

2025/05/23

In this episode of Daily Value, we look inside the NAD+ wars - breaking down the science, the hype, and the controversy surrounding Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN). These two molecules have been promoted as keys to longevity, but the story is far more complex. We’ll look at the biochemistry of NAD+ metabolism, compare what the research really says about NR and NMN, and dig into the regulatory drama that’s shaped their (NMN’s) availability. Most importantly, we...

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20:06

The Vitamin D-ilemma: Are the New Guidelines Missing...

Daily Value ·

2025/05/21

Vitamin D recommendations in 1941 began this debate. Over the years, updated guidelines have continued to spark controversy and debate in the field of vitamin D research. In this episode of Daily Value, we look at the recent “Vitamin D-ilemma” reinvigorated by the Endocrine Society's updated 2024 guidelines. These new recommendations have dialed back routine testing and supplementation targets, igniting pushback from leading researchers who argue we might be overlooking significant health ben...

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11:34

Creatine Chronicles: Examining Safety and Dispelling...

Daily Value ·

2025/05/19

Debunking Myths: The safety and side effects of creatine supplementation. In this episode of Daily Value we look into the safety concerns surrounding creatine supplementation. Creatine, a well-researched dietary supplement known for its muscle-building and performance-enhancing benefits, has sparked numerous myths about its effects on kidneys, hair loss, and dehydration. We will evaluate recent studies and scientific evidence to address these myths. Topics include creatine's impact on water r...

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8:06

The Most Neuroprotective Compound You've Never Heard Of

Daily Value ·

2025/05/16

In this episode of Daily Value, we look at a forgotten compound found in common vegetables such as kale, spinach, and broccoli. Discovered in the 1930s and initially thought to be a vitamin (dubbed “Vitamin P”), this compound has recently demonstrated significant potential in neuroprotection. This compound may soon become an essential component in neuroprotective and longevity formulations. 00:00 Introduction to Brain Health Molecules 00:19 The Forgotten Flavonoid 01:08 Historical Background ...

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9:06

The Melatonin Mystery: Are Guidelines Wrong?

Daily Value ·

2025/02/19

In this episode of Daily Value, we look at newer research on melatonin that challenges conventional wisdom. A recent meta‐analysis questions current clinical guidelines on melatonin use for sleep, suggesting there may be a dual (Dose X Time effect) secret to optimizing its effects. We’ll break down the scientific clues behind optimal dosing, timing, and formulation, leaving you to wonder if you've been taking melatonin all wrong. Discussion Points: The clinical recommendations for melatonin m...

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9:59

B Vitamins & Neuropsychiatric Disorders—A Causal...

Daily Value ·

2025/02/17

In this episode of Daily Value, we look at the latest research on B vitamins and their in neuropsychiatric disorders. A newly published meta-analysis suggests a causal relationship between B vitamin deficiencies and neuropsychiatric disorders. We will break down the scientific findings on B6, B12, and folate, shedding light on their roles in conditions like Parkinson’s disease. Discussion Points: How recent genetic studies support a causal link between B vitamin deficiencies and mental health...

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10:57

The Forgotten Vitamin for Brain Health

Daily Value ·

2025/02/12

In today’s episode of Daily Value, we explore the possibly underappreciated role of vitamin K in brain health and neuroprotection. Recent research (doi: 10.3389/fnut.2024.1396707) reveals a connection between dietary vitamin K intake and reduced levels of neurofilament light chain, a potential biomarker for neurodegeneration, particularly in middle-aged and older adults. We’ll discuss how vitamin K supports neuronal function, what specific forms of vitamin K are most important, and how ...

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9:40

Beyond the Gym: Creatine’s Role in Women’s Health

Daily Value ·

2025/02/10

In this episode of Daily Value, we look at the emerging research on creatine supplementation in women’s health—beyond its well-established role in exercise performance. With evidence mounting on creatine’s impact across menstruation, pregnancy, postpartum recovery, and menopause, we discuss how it supports cognition, mood stabilization, and bone health throughout a woman’s lifespan. Discussion Points: Creatine & Hormonal Fluctuations: How estrogen and progesterone influence creatine uptak...

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14:59

B12 Deficiency: Uncovering the Silent Threat to...

Daily Value ·

2025/02/05

In today’s episode of Daily Value, we take a closer look at a commonly overlooked but essential nutrient: vitamin B12. Known as cobalamin, vitamin B12 deficiency can lead to severe neurological, hematological, and cognitive issues if left unchecked. We’ll cover the causes behind this growing issue, from dietary intake to malabsorption. Episode Talking Points: The role of B12 in nervous system function and red blood cell production.Causes of B12 deficiency, including dietary factors, autoimmun...

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8:12

How Male Alcohol Consumption Can Shape Offspring...

Daily Value ·

2025/02/03

In this episode of Daily Value, we look at how paternal alcohol consumption before conception could influence offspring health, longevity, and even accelerate aging. Referencing studies from Andrology (PMID: 38044754) and Aging and Disease (PMID: 39122451), we examine how sperm RNA modifications and mitochondrial dysfunction may persist long after alcohol cessation—potentially programming offspring for metabolic disorders, reduced NAD+ levels, and faster cellular aging. Discussion Points: Spe...

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80 results

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