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PODCAST

Functional Medicine Reality Podcast

Dr. Mark Su MD, Functional Medicine Practitioner for Health and Longevity

The Functional Medicine Reality Podcast exposes the truth about what really happens in healthcare and why so many patients with complex, chronic conditions are left searching for answers. Hosted by Dr. Mark Su, founder & leader of RootSeek’s nationwide virtual care team, this show goes beyond quick fixes to uncover the root causes of illness—like Lyme disease and co-infections, mold toxicity, gut dysbiosis, hormone imbalances, hidden infections, and heavy metal exposure.Each episode reveals real

health & fitness medicine

All Episodes

19:30

24. ADHD, Stimulants, and Real Results with Dr. Mark Su

Functional Medicine Reality Podcast ·

2026/05/24

Once a month I open up one hour to five people only. Real questions, real answers, real direction. Grab your spot at go.rootseekhealth.com/askdrmark. You've probably been told the story about stimulant medication goes one way. You take it, you focus better, maybe you sleep less, maybe you lose your appetite. That's the whole conversation. But what if the real story is bigger than that, and most people never get to hear it because nobody in the exam room takes the time to tell it? In t...

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38:47

23. Hype or Hope? How to Spot Mold Misinformation...

Functional Medicine Reality Podcast ·

2026/05/17

If you've ever Googled "mold illness treatment" at midnight, desperate for answers, you already know how overwhelming it gets. The supplements, the sprays, the lab reports with pages of frightening health warnings, it can feel like you're drowning in information and still no closer to knowing what to actually do. This conversation is for you. Dr. Mark Su sits down again with Mike Schrantz, IEP, the environmental professional he trusts most when it comes to what's actually happening inside the...

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8:30

22. Pharmaceuticals vs. Supplements: What Your Doctor...

Functional Medicine Reality Podcast ·

2026/05/10

If you've ever stood in the supplement aisle wondering whether any of it actually works, or sat across from a doctor who handed you a prescription without explaining why, this conversation is for you. The question of pharmaceuticals versus supplements comes up constantly in functional medicine, and the honest answer is more nuanced than most people expect. In this episode, Dr. Mark Su breaks down the real-world comparison between prescription medications and natural supplements, not from a pl...

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72:05

21: How to Choose Supplements You Can Actually Trust,...

Functional Medicine Reality Podcast ·

2026/05/03

Got Lab Results But No Real Answers? Download your free guide: rootseekhealth.com/labs You've probably stood in a supplement aisle, or scrolled past an influencer ad, and thought, I have no idea if any of this actually works. Maybe you've spent real money on things that did nothing. Maybe your doctor shrugged when you asked. That confusion is not a personal failing. It's the supplement industry doing exactly what an under-regulated industry tends to do, and today we're pulling back the ...

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63:54

20: Hair Loss, Peptides, and Taking Ownership of Your...

Functional Medicine Reality Podcast ·

2026/04/26

Got Lab Results But No Real Answers? Download your free guide: rootseekhealth.com/labs If you've ever walked out of a doctor's office feeling like you were handed a prescription instead of an answer, you're not alone. That rushed, "here's a pill, see you later" experience is something a lot of people are navigating right now, and it leaves you with more questions than when you walked in. This week, Dr. Mark Sue sits down with Luigi, a sharp, self-advocating young guy in his twenties who came ...

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54:23

19: Alcohol, Self-Awareness, and Root Cause Health: A...

Functional Medicine Reality Podcast ·

2026/04/19

Got Lab Results But No Real Answers? Download your free guide: rootseekhealth.com/labs Ready to find out what's actually going on in your body? Book a consult at rootseekhealth.com. What does alcohol have to do with functional medicine? More than you might think. In this episode, Dr. Mark Su sits down with patient and guest MaryJo for one of the most honest, human conversations the Functional Medicine Reality Podcast has had yet. No agenda, no judgment, just two people peeling back a topic th...

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80:12

18. Sick Home, Sick Body: A Real Mold Remediation...

Functional Medicine Reality Podcast ·

2026/04/12

Got lab results but no real answers? Download your free guide and finally understand what your body is trying to tell you: rootseekhealth.com/labs Episode Overview Mold. It's one of those words that makes people freeze, panic, or reach for their wallet before they even know what they're dealing with. In this episode of the Functional Medicine Reality Podcast, Dr. Mark Su sits down with Michael Schrantz, Indoor Environmental Professional (IEP) and founder of Environmental Analytics, for...

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20:31

17. Statin Side Effects, Muscle Pain, and Brain Fog:...

Functional Medicine Reality Podcast ·

2026/04/05

What if the knee pain you've been blaming on age is actually a statin side effect? That's a question worth sitting with. And it's one of the reasons I wanted to do this episode, because I see this pattern in real people, in real conversations, all the time. Someone's been on a statin for a few years. They're moving less, feeling foggy, their joints ache. And when they bring it up, they're told it's just part of getting older. It doesn't have to be that way. In this episode, I walk you through...

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44:39

16: Parasites, Lyme Disease & Cellcore: What Actually...

Functional Medicine Reality Podcast ·

2026/03/29

Before we dive in, if you've been on this road for a while and you're still not getting the answers you deserve, head over to RootSeekHealth.com and take our free health quiz. It only takes a few minutes and it's built to help figure out what your body might actually be needing right now. I'll be upfront. I walked into my first encounter with Dr. Todd Watts as a full-on skeptic. I'm an MD. I like data. I've literally told vendors at conference booths, hey, I'm not buying anything, fair warnin...

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68:55

15. What Causes Autoimmunity? A Deep Dive into...

Functional Medicine Reality Podcast ·

2026/03/22

Hey friends, what if we stopped fighting over labels and actually started treating the mechanisms behind what's making people sick? That's the question driving today's conversation with Dr. Jessica Lasky-Su from Harvard Medical School and Brigham and Women's Hospital. Here's the thing. Her team is working at the edge of some really fascinating science, genetics, epigenetics, proteomics, metabolomics, antibody profiling. And what we dig into is how long COVID research, viral exposures, and aut...

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53:18

14. Living with Chronic Lyme Disease: Resilience,...

Functional Medicine Reality Podcast ·

2026/03/15

What does “I feel good” mean after years of chronic Lyme and a major surgery that reshapes your body and your identity? We sit down with Mary Jo to unpack a tender, determined third chapter: living well after treatment, navigating a post-hysterectomy reality, and rebuilding confidence without ignoring limits. The result is a rare blend of practical playbooks and soul-level honesty—how to budget energy to avoid push-crash, why anti-inflammatory eating clarifies symptoms fast, and where simple ...

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62:53

14. Gut Health, Mental Clarity, and the Search for...

Functional Medicine Reality Podcast ·

2026/03/08

In this episode, I sit down with Sebastian, a family friend and college student, for an open and thoughtful conversation about health, food, mental clarity, and the overwhelm of modern wellness information. This is a rare and refreshing look at how the younger generation is thinking about health and asking questions many adults never learned to ask. Seb shares how his interest in lifting, performance, and nutrition gradually turned into something deeper. What started as a focus on strength an...

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57:55

12. Functional Medicine and Mold: A Deep Dive into...

Functional Medicine Reality Podcast ·

2026/03/01

In this episode of the Functional Medicine Reality Podcast, I sit down again with my friend and colleague Mike Schrantz, an Indoor Environmental Professional I often call the “Doctor of Homes.” I’m the “Doctor of People,” and together we work at the intersection where sick buildings and sick bodies collide. Today we step into a thorny topic that affects a lot of patients and a lot of practitioners: human mold testing, specifically urine mycotoxin testing. If you have ever had a urine mycotoxi...

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15:09

11. Unveiling the Truth: Financial Incentives in...

Functional Medicine Reality Podcast ·

2026/02/22

One of the questions I am asked most often by patients is this: “Don’t doctors get paid to prescribe medications?” It is a fair question. And if you have ever left a medical visit feeling rushed, unheard, or confused about why a prescription was offered when you wanted to talk about lifestyle change, you are not alone. The short answer, from my experience, is no. Doctors are not paid directly for writing prescriptions. I have never seen that arrangement in my own career. But the longer and mo...

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58:13

10. Understanding Your Symptoms: The Critical Role of...

Functional Medicine Reality Podcast ·

2026/02/15

Hey friends. This is one of those foundational conversations that quietly shapes everything we do in healthcare, yet it’s rarely talked about outside medical training. In this episode, I walk you through the concept of differential diagnosis, what it is, why it matters, and how overlooking it can delay healing or, in some cases, cause real harm. Differential diagnosis simply means creating a thoughtful list of all the possible causes of a symptom before jumping to conclusions. It’s not about ...

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66:17

09. Exercise as Medicine VO2 Max, Zone 2, and the...

Functional Medicine Reality Podcast ·

2026/02/08

Welcome back to the Functional Medicine Reality Podcast. I'm Dr. Mark Su, and today we're pivoting from the chronic inflammation world into the longevity space. I'm here with Cooper Paul, a pulmonary hypertension specialist at a major academic hospital in Boston and a true longevity medicine enthusiast who's taught me an incredible amount over the last few years. Here's the thing. We all know exercise is good for us. But what if I told you there's data showing that going from a low VO2 max to...

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50:17

08. Living with Lyme: Mary Jo’s Journey from...

Functional Medicine Reality Podcast ·

2026/02/01

Welcome back to the Functional Medicine Reality Podcast. I'm Dr. Mark Su, and this is part two of my conversation with Mary Jo Anderson. If you caught our first episode together, you know we covered the long, painful road to getting a Lyme disease diagnosis. Today we're diving into what happens after you finally have answers. Here's the thing. Getting a diagnosis doesn't mean everything magically gets better overnight. Mary Jo's story is proof of that. And I think her willingness to share the...

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58:06

07. Understanding Mold: Myths, Realities, and...

Functional Medicine Reality Podcast ·

2026/01/25

Alright, so here's one I get asked constantly: Do I really need to throw out all my belongings if there's mold in my house? If that question's been keeping you up at night, or if you're stuck wondering whether dealing with mold means going bankrupt and starting over, take a deep breath. This episode's for you. I brought back Mike Schrantz, one of the most networked indoor environmental professionals in the country. He's what I call a "doctor of houses and buildings." And we got into the real,...

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13:24

06. Understanding Your Symptoms: The Critical Role of...

Functional Medicine Reality Podcast ·

2026/01/18

Hey friends, this one's for both practitioners and patients who've been around the functional medicine world for a while. Here's the thing. When you've been dealing with chronic symptoms for months or years, it's really easy to fall into patterns. You start assuming every flare-up is the same old story. SIBO acting up again. Mold toxicity. Food sensitivities. But what if it's not? I'm talking about the differential diagnostic list, which is just a fancy way of saying: all the possible things ...

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46:47

04. Humanity in Healthcare: A Candid Talk with Dr....

Functional Medicine Reality Podcast ·

2025/12/28

In this episode, I sit down with Dr. George Papanicolao, long-time mentor, colleague, and friend, for one of the most honest conversations we’ve ever had publicly about medicine, humanity, and what it really means to care for people. George was my first boss early in my career and has spent more than three decades practicing medicine across vastly different settings, from the Navajo Nation to primary care to the UltraWellness Center. This conversation is not about protocols or supplements. It...

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