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PODCAST

Note to File: A Clinical Research Podcast

Note to File is a podcast for clinical research sites - interviews, best practices, and candid commentary from Brad Hightower, founder of Hightower Clinical and clinical research professional.

business management

All Episodes

27:38

Palantir in Clinical Trials? Industry News, Stock...

Note to File: A Clinical Research Podcast ·

2025/07/30

We discuss the new partnership between Velocity Clinical Research and Palantir, recent stock market bumps in the CRO sector, and the ongoing challenges facing US clinical trials. Plus, we chat about global research trends, upcoming conferences, and invite your questions for future episodes. Tune in for candid commentary, industry insights, and a bit of fun along the way!

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01:00:39

Building Community & Creativity in Clinical Research:...

Note to File: A Clinical Research Podcast ·

2025/07/28

Jeff Smith and Michelle Jones join us to explore the origins and evolution of the Innovation Network Gathering (ING). Discover how ING is redefining clinical research conferences by fostering creativity, authentic connections, and purpose-driven collaboration. Learn about the event’s unique approach—small group dive teams, curated talks, and intentional community-building in a charming setting. Hear about new features for this year, including Navigate workshops and partner-led initiatives, and get

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51:38

Investment, Integration & Patient Access with Laura...

Note to File: A Clinical Research Podcast ·

2025/07/21

Join us for an insightful conversation with Laura Hilty as we dive into the latest trends and challenges in the clinical research industry. We discuss the differences between venture capital and private equity investment, the complexities of site networks, integration and interoperability hurdles, and innovative ways to increase patient access to clinical trials. Plus, hear Laura’s perspective on the future of clinical research and what it takes to drive meaningful change in the industry.

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27:04

Note to File Hits the Road and Reverse Mergers

Note to File: A Clinical Research Podcast ·

2025/07/14

In this episode, we discuss upcoming conferences like Innovation Gathering, Veeva Summit, and SOS, and explore how these events are elevating site voices and fostering real connections in the industry. We also touch on the recent Circuit Clinical/Lightship merger news and talk about the importance of networking and support during industry layoffs. Don’t forget to check out notetofilepodcast.com for more info, to submit your questions or topics, and to sign up for our newsletter for exclusive updates

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55:10

AI, Ethics & Cookies: Clinical Research Trends with...

Note to File: A Clinical Research Podcast ·

2025/07/07

Join Brad, Denali, and guest Dan Schell from Clinical Leader for a lively and insightful conversation on the latest trends in clinical research. From the real-world impact of AI and the evolution of site networks to the challenges of technology adoption and industry ethics, this episode dives deep into what’s shaping the future of clinical trials. Plus, enjoy some lighthearted banter about cookies and the quirks of the industry. Whether you’re a research professional or just curious about the field,

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33:28

Catfish, Cancer Conferences, and Clinical Research Chaos

Note to File: A Clinical Research Podcast ·

2025/07/02

Join us for a lively episode where we kick things off with tales of catfish, noodling, and regional fishing quirks before diving into the world of clinical research. We discuss the latest cancer center conferences, the persistent challenges facing the industry, and why so many professionals are still relying on spreadsheets and workarounds. Plus, we chat about industry layoffs, the evolving role of CROs, and the reality that sometimes, everyone’s just figuring it out as they go.

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54:34

Sites as Customers: Transforming Clinical Research...

Note to File: A Clinical Research Podcast ·

2025/06/25

Laura O'Donnell from GSK challenges the traditional sponsor-site relationship in clinical research. She advocates for treating sites as true customers, not just vendors, by emphasizing transparency, human connection, and meaningful engagement. We dive deep into the challenges sites face, from tech complexity to communication gaps, and explore how the industry can create more collaborative, supportive partnerships that ultimately benefit patients and scientific progress.

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29:52

The State of Clinical Research: A Candid Conversation...

Note to File: A Clinical Research Podcast ·

2025/06/23

Former FDA Commissioner Dr. Robert Califf provides a brutally honest assessment of the current clinical research landscape. He discusses the critical challenges facing medical innovation, from overly complex clinical trials to profit-driven healthcare systems. Dr. Califf offers insights into why clinical research has become increasingly difficult, shares his vision for a more integrated learning health system, and provides hope for researchers and healthcare professionals looking to drive meaningful

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55:23

HIPAA Myths, Industry Risks and White Hot Rage

Note to File: A Clinical Research Podcast ·

2025/06/18

In this electrifying episode, legal experts Darshan Kulkarni and Edye Edens dive deep into the complex world of clinical research. From HIPAA compliance and corporate practice of medicine to the hidden risks facing research sites, they break down critical legal insights with their signature wit and candor. Prepare for an eye-opening conversation that goes beyond the typical industry talk.

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27:03

Clinical Research Mergers, Secrets, and Shortcuts

Note to File: A Clinical Research Podcast ·

2025/06/16

In this episode of Note to File, we dive into the recent merger between Circuit and Lightship, explore the behind-the-scenes challenges of clinical research site training, and discuss the ongoing consolidation in the clinical trial industry. Join us for candid insights, industry gossip, and a no-holds-barred conversation about the realities of clinical research.

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25:03

Mexico's Research Boom, Javara's Funding and Industry...

Note to File: A Clinical Research Podcast ·

2025/05/30

We discuss National Clinical Trials Day, Mexico's emerging clinical research landscape, and Javara's recent Series C funding. We dive into the challenges of oncology trials, explore the role of venture capital in healthcare, and share some industry gossip about Signant Health's recent job posting for a Director of Reputation and Crisis Communications. Somehow Note to File has existed for 5 years now....

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54:11

Digital Health, Clinical Trials, and Beyond with...

Note to File: A Clinical Research Podcast ·

2025/05/16

In this episode we sit down with healthcare veteran Matthew Holt, founder of The Health Care Blog and Health 2.0. Matthew shares his fascinating journey from Stanford grad student to healthcare technology commentator, offering candid insights into digital health, clinical trials, and the challenges of healthcare innovation. From discussing the potential of GLP-1 drugs to exploring the future of longevity research, this conversation provides a witty and insightful look at the evolving landscape of

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30:21

Clinical Research Confessions: PE, Trials, and...

Note to File: A Clinical Research Podcast ·

2025/05/14

In this episode of Note to File, we dive deep into the world of clinical research, exploring the challenges of resident physician training, the impact of private equity on clinical trial management systems, and the often-unspoken ethical dilemmas in the field. Join us as we unpack difficult sponsor behaviors, share hilarious research confessions, and offer candid insights into the clinical research landscape. From PE investments to research sins, this episode is packed with humor, honesty, and

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48:59

Clinical Trials 2.0: AI, Predictions, and the Future...

Note to File: A Clinical Research Podcast ·

2025/05/09

Special Pope election edition. In this episode, Rohit Nambisan from Lokavant and Jonathan Crowther from Pfizer discuss their innovative approach to clinical trial forecasting. They explore how advanced data analytics and AI can help predict and improve trial operational success, from site selection to protocol design. The conversation delves into reducing uncertainty, enhancing communication between sponsors and sites, and leveraging technology to make clinical research more efficient and

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50:03

CROs are Broken: Fixing Clinical Trials from the...

Note to File: A Clinical Research Podcast ·

2025/05/08

In this episode, Meri Beckwith from Lindus Health discusses his journey from venture capital to clinical research, sharing insights on the inefficiencies of traditional CROs. He explains how Lindus is taking a different approach by aligning incentives, focusing on patient experience, and developing innovative trial models. The conversation explores the challenges in clinical trials, from data collection to site management, offering a fresh perspective on how the industry might evolve.

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35:29

Sticky Notes 4/30/25

Note to File: A Clinical Research Podcast ·

2025/05/05

In this episode of Sticky Notes, Brad & Denali dive into the latest trends in clinical research, exploring how younger adults are getting medical advice from social media, the potential impact of pharmaceutical tariffs on R&D, and the evolving landscape of decentralized clinical trials. We discuss the challenges and opportunities of involving healthcare providers in clinical research, and touch on recent layoffs in the CRO industry. Join us for an insightful and candid conversation about the current

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45:57

Bree Burks - Veeva

Note to File: A Clinical Research Podcast ·

2025/04/28

We sit down with Bree Burks from Veeva to discuss the company's latest innovations in clinical research technology. We dive deep into Veeva's upcoming CTMS (Clinical Trial Management System), their strategy for connecting sponsors and sites, and the importance of creating more streamlined, user-friendly technology for clinical research sites. Bree shares insights from her nursing background and Veeva's mission to simplify technology for sites, making clinical trials more efficient and

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30:32

Sticky Notes 4/15/2025

Note to File: A Clinical Research Podcast ·

2025/04/21

In this episode, Brad and Denali dive into recent industry developments, including Bay Pine's $1.5 billion acquisition of CenExel clinical research site network, the FDA's potential shift to AI-based animal testing alternatives, growing challenges with clinical trial recruitment and public trust, emerging pharmaceutical import tariffs, and the ongoing wave of layoffs in the life sciences sector. The discussion offers candid insights into the evolving landscape of clinical research, technology, and

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52:55

Jim Kremidas - AMRC

Note to File: A Clinical Research Podcast ·

2025/04/14

In this episode Jim Kremidas, Executive Director of the Association of Multi-Site Research Corporations (AMRC), discusses the evolving landscape of clinical research sites. We explore how multi-site research corporations are working to improve operational efficiency, quality standards, and patient experiences in clinical trials. Kremidas shares insights from his extensive background in pharmaceutical research highlighting the potential benefits of site network consolidation and standardization.

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01:02:43

From The Archives: Jamie Massengill - SSM Health

Note to File: A Clinical Research Podcast ·

2025/04/07

In this episode, we sit down with Jamie Massengill from SSM Health to unpack the complex world of clinical research in community healthcare. We dive deep into the challenges of launching successful research programs, exploring innovative partnership models, physician engagement strategies, and how community hospitals can transform clinical trials. Learn how breaking traditional barriers can create meaningful research opportunities that benefit patients, physicians, and healthcare systems alike.

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136 results

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