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PODCAST

Decera Clinical Education Infectious Disease Podcast

Decera Clinical Education

Weekly updates on new data and best practices in patient care for a variety of infectious diseases including COVID-19, HIV, and viral hepatitis, from Decera Clinical Education. Gain practical strategies and earn CME/CE credit for selected episodes.

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All Episodes

00:47:15

Viral Hepatitis Update: CCO Independent Conference...

Decera Clinical Education Infectious Disease Podcast ·

2023/07/11

In this episode, Stefan Zeuzem, MD, discusses new data on viral hepatitis presented at EASL 2023, including:Hepatitis B virusDurability of response with bepirovirsenHBsAg loss with siRNA VIR-2218 combined with either VIR-3434 (novel monoclonal antibody) or pegIFN-alfaHepatitis delta virus96-week follow-up of immediate vs delayed bulevirtideOff-treatment response for lonafarnib + ritonavir ± pegIFN-alfa Safety and efficacy outcomes with siRNA JNJ-3989 + nucleos(t)ide analogueHepatitis C

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00:27:38

Treatment of Skin and Soft Tissue Infections

Decera Clinical Education Infectious Disease Podcast ·

2023/07/11

In this episode, Kyle Molina, PharmD, BCIDP, provides an overview of treatment of skin and soft tissue infections (SSTIs) and challenges in practice. Listen as he gives perspectives on:Guideline recommendations for treatment of purulent and nonpurulent SSTIsLogistical challenges with IV and oral antibioticsPros and cons of various locations of careData supporting the safety and efficacy of long-acting lipoglycopeptides for treatment of SSTIsUse of long-acting lipoglycopeptides in special populations

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00:26:07

Answering the Questions on Which HIV PrEP for Which...

Decera Clinical Education Infectious Disease Podcast ·

2023/07/03

In this episode, Latesha Elopre, MD, MSPH, and Jason Farley, PhD, MPH, ANP-BC, FAAN, FAANP, AACRN, answer questions about HIV PrEP including:How long someone can receive PrEP and the monitoring that is needed over timeRecommendations for monitoring bone health while receiving oral PrEPTreatment as prevention and PrEP efficacy data and options for people who inject drugsThe role of circumcision in HIV preventionThe use of PrEP in pregnancyConcern for ART resistance if someone seroconverts while

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00:10:17

Q&A on Barriers to HIV PrEP: Pharmacist Perspectives

Decera Clinical Education Infectious Disease Podcast ·

2023/06/27

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, FCCP, and Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES, discuss key considerations to barriers to PrEP uptake, including:Limited data on “on-demand” PrEP in cisgender women Strategies on improving communication with non‒English-speaking populations Role of pharmacists with injectable PrEP CDC PrEP guideline recommendations on routine HIV-1 RNA testing Engaging with pregnant persons who might want access to PrEP in the pharmacy

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00:39:55

Older Adults: Overcoming HBV Barriers

Decera Clinical Education Infectious Disease Podcast ·

2023/06/23

In this episode, Robert S. Brown, Jr., MD, MPH; Nancy Reau, MD; and Eric, a person living with chronic hepatitis B, discuss solutions for overcoming barriers to HBV care in older adults, including:Awareness of HBV and CHB in older adultsUpdated HBV screening and vaccination recommendationsMonitoring of renal and bone diseaseAdjustment of monitoring and treatment as a person with HBV agesPresenters: Robert S. Brown, Jr., MD, MPHVincent Astor Distinguished Professor of MedicineChief, Division of

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00:39:58

Hepatitis Delta in Focus: Episode 4 of Answering the...

Decera Clinical Education Infectious Disease Podcast ·

2023/06/22

In this episode, Tarik Asselah, MD, PhD, and Ira Jacobson, MD, provide expert insight on HDV screening, diagnosis, and management, including:Approach to screeningBarriers to screening (eg, test availability)Disease progression and complicationsDifferentiating between coinfection and superinfectionApproach to treatment (eg, whom to treat and when, treatment options, considerations for combination therapy)Management of patients with decompensated cirrhosisSurrogate markers to measure treatment

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00:12:51

Preparing for the Fall: New RSV Vaccine Approvals

Decera Clinical Education Infectious Disease Podcast ·

2023/06/19

In this episode, Helen Y. Chu, MD, MPH, shares updates on RSV vaccines, including:An overview of vaccine candidates under investigationRecently FDA-approved RSV vaccines for older adultsConsiderations for the next respiratory viral seasonCoadministration of RSV vaccines with other respiratory viral vaccines (eg, influenza, SARS-CoV-2)Target populations for RSV vaccinationRSV prevention in infants with the maternal vaccine and monoclonalFaculty:Helen Y. Chu, MD, MPHAssociate Professor of

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00:42:02

Hepatitis Delta in Focus: Episode 3 of Answering the...

Decera Clinical Education Infectious Disease Podcast ·

2023/06/19

In this episode, Nancy Reau, MD, and Heiner Wedemeyer, MD, provide expert insight on HDV management, including:Use of noninvasive imaging or biopsy for staging liver diseaseScreening for hepatocellular carcinomaHBV treatmentRole of comedications (eg, erythropoietin, eltrombopag)Approach to complex cases, such as patients with:Significant fibrosis and low HDV RNA levelsHepatitis delta antibody positivity, but HDV RNA negativityHIV coinfectionDecompensated or recently decompensated

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00:11:58

Modifying ART in the Presence of Hyperlipidemia:...

Decera Clinical Education Infectious Disease Podcast ·

2023/06/09

In this episode, Maunank Shah, MD, PhD, discusses using HIV-ASSIST to optimize treatment for both HIV and hyperlipidemia. Listen as he covers:Hyperlipidemia and cardiovascular disease risk among people living with HIVRecommendations for lipid screening for people living with HIVUsing HIV-ASSIST to support ART treatment decisions for people living with HIV with comorbiditiesHow HIV-ASSIST prioritizes certain ART agents in the setting of hyperlipidemia, including:Deciding between bictegravir,

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00:18:00

The Burden of Skin and Soft Tissue Infections:...

Decera Clinical Education Infectious Disease Podcast ·

2023/06/08

In this episode, Martin Krsak, MD, MSc, FASAM, provides background and context on skin and soft tissue infections. Listen as he gives perspectives on:Epidemiology and clinical outcomesEconomic impactBacterial etiologyImportance of appropriate antimicrobial prescribingClinical presentationSeverity classification and distinction between purulent and nonpurulent infectionsRole of incision and debridement vs antimicrobial managementComplications to be ruled out prior to treatmentFaculty:Martin Krsak,

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00:46:49

Choosing Between Initial ART Options: Answering the...

Decera Clinical Education Infectious Disease Podcast ·

2023/06/06

In this episode, Marta Boffito, MD, PhD, FRCP, and Michelle Cespedes, MD, MS, discuss initial ART options, including:Recommended first-line ART options for most PWH according to DHHS, IAS-USA, EACS, BHIVA, and WHO guidelines Data for weight gain after ART initiation with different ARV classes and drugsWeight gain disparities by race and gender after ART initiationData from the RESPOND study including risk factors for weight gain and CV event risk with INSTI vs non-INSTI–based ART The impact of

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00:05:56

Choosing ART for HIV With HBV and HCV Coinfections:...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/30

In this episode, Carolyn Chu, MD, MSc, FAAFP, AAHIVS, discusses using HIV-ASSIST to aid in the selection of an ART regimen for PWH coinfected with HBV and HCV. Listen as she covers:How HIV-ASSIST supports ART selection in primary careUpdates to viral hepatitis recommendations including: CDC HBV screening and testing recommendations AASLD simplified HCV treatment approach for PWHHIV-ASSIST for managing HIV/HBV coinfections, including ensuring that NRTIs that are effective

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00:10:24

Integrating New Data on LA ART From CROI 2023:...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/22

In this episode, Amanda Binkley, PharmD, BCIDP, AAHIVP, and Nimish Patel, PharmD, PhD, AAHIVP, discuss clinically relevant data on long-acting ART from CROI 2023, including:LA CAB + RPV in San Francisco’s Ward 86 Safety Net Clinic Serving Publicly Insured PWHSOLAR: Randomized Switch to LA CAB + RPV From BIC/FTC/TAFAmanda Binkley, PharmD, BCIDP, AAHIVPClinical Pharmacy Specialist Infectious DiseaseDepartment of PharmacyPenn Presbyterian Medical CenterPhiladelphia, PennsylvaniaNimish Patel, PharmD,

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00:41:52

Christine Katlama and Babafemi Taiwo: Answering the...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/16

In this episode, Christine Katlama, MD, and Babafemi Taiwo, MBBS, discuss optimizing ART for people with HIV who are treatment experienced or failing a current ART regimen, including:Recycling agents from the NRTI, NNRTI, INSTI, and PI classes in salvage ART regimensMaintaining NRTIs in second-line and salvage ART regimens, including the use of 3TC, TFV, and ABCART regimen simplificationWhen to perform genotypic resistance testing, including for PWH who have been off ARTWhen to perform DNA

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00:08:09

Preconception ART Selection: Using HIV-ASSIST

Decera Clinical Education Infectious Disease Podcast ·

2023/05/11

In this episode, Sonya Krishnan, MD, MHS, discusses using HIV-ASSIST to aid in the selection of an ART regimen for a virologically suppressed PWH who is planning a pregnancy. Listen as she covers:How to input patient specific factors into the HIV-ASSIST toolDiscussion of available education sheets to review the data and recommendations for her current ART regimen in pregnancyAn explanation of why some regimens are ranked lower because of adherence factors such as increased pill burden or dosing

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00:27:13

Long-Acting ART: Cabotegravir Plus Rilpivirine

Decera Clinical Education Infectious Disease Podcast ·

2023/05/10

In this episode, Ian Frank, MD, discusses long-acting HIV treatment with cabotegravir plus rilpivirine for people with HIV, including:Efficacy data with every-8-week dosingReal-world use in people with viremia Initiation and continuation strategiesVirologic failure dataSafety information Presenter:Ian Frank, MDAssociate ChiefDivision of Infectious DiseasesProfessor of MedicineUniversity of PennsylvaniaPhiladelphia, PennsylvaniaTo download the slides: https://bit.ly/3HX1GGn To view the full online

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00:36:36

COVID-19 Update: Independent Conference Coverage of...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/05

In this episode, Patrick W. G. Mallon, MB, BCh, PhD, FRACP, FRCPI, discusses new data on COVID-19 presented at ECCMID 2023, including:Treatment in special populationsREDPINE: remdesivir in people with renal impairment hospitalized for COVID-19 pneumoniaRemdesivir and readmission for COVID-19 in immunocompromised patientsMolnupiravir vs nirmatrelvir plus ritonavir for COVID-19 with hematologic malignancyManagement of patients with severe diseaseRECOVERY: higher-dose vs standard-dose corticosteroids

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01:14:42

2023 Audio Recap: Principles of Outpatient COVID-19...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/03

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss strategies for managing ambulatory patients with acute or previous COVID-19 infection, including:Current COVID-19 landscapeRapid antigen tests and PCR testsRisk stratification of patients who have a positive SARS-CoV-2 testAntiviral treatment (nirmatrelvir + ritonavir, remdesivir, and molnupiravir)Long COVIDPresenters:Renslow Sherer, MDDirector, International HIV Training CenterProfessor of MedicineSection of Infectious

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00:30:05

Complicated Clinical Infections: Clinical Impact of...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/03

In this episode, David van Duin, MD, PhD, FIDSA, FAST, discusses new data on complicated clinical infections presented at ECCMID 2023, including:Gram-negative resistancePharmacokinetic and clinical outcomes in patients receiving meropenem/vaborbactam for KPC-producing carbapenem-resistant Enterobacterales infectionsComparative study of cefiderocol- vs colistin-containing regimens for CRAB VAP with concomitant bacteremiaReal-world use of imipenem/cilastatin/relebactam for the treatment of infections

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00:57:16

2023 Audio Recap: Practical Case Studies in...

Decera Clinical Education Infectious Disease Podcast ·

2023/05/02

In this episode, Tracey Piparo, PA-C, and Renslow Sherer, MD, discuss cases of nonhospitalized patients with COVID-19, including:Young, healthy patient with no risk factorsYoung, healthy patient with risk factorsOlder patient with immunocompromiseOlder patient with renal dysfunctionPatient experiencing hypoxia Presenters: Tracey Piparo, PA-C Department of Palliative Medicine RJWBarnabas New Brunswick, New Jersey Renslow Sherer, MD Director, International HIV Training Center Professor of

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