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PODCAST

Answers from the Lab

Mayo Clinic Laboratories

A Mayo Clinic curated podcast sharing Mayo Clinic knowledge and advancements on the state of testing, science, and people who are making it happen behind the scenes.

health & fitness medicine

All Episodes

13:06

Looking at the big picture: Dr. Bill Morice

Answers from the Lab ·

2022/09/08

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and CEO and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss current challenges in lab medicine and what it means to be a laboratory leader, including innovation, test stewardship, and the use of digital pathology.

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18:38

Precision therapeutics can individualize depression...

Answers from the Lab ·

2022/09/06

(00:31) Can you both tell us a little bit about yourselves and your backgrounds? Dr. Moyer, do you want to start?(01:51) Your background, Dr. Janetto?(02:47) Please provide an overview of major depressive disorder and the test that Mayo Clinic Laboratories has available for therapeutic drug monitoring as well as pharmacogenomics.(07:05) Which patients should have this testing, and when should it be performed? (11:33) What alternative test options are available, and how do they

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11:33

State-of-the-art genetics panel optimizes kidney...

Answers from the Lab ·

2022/08/30

(00:31) Would each of you share a little about yourselves and your backgrounds?(01:17) Could you please provide us with an overview of what types of genetic testing for inherited kidney diseases are available Mayo Clinic Labs?(02:35) Can you expand on why genetic testing for kidney disease is important?(04:30) Who could benefit from genetic testing for inherited kidney diseases?(05:55) What types of variants are detected by these new genetic panels at Mayo Clinic Labs?(07:05) How would you

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14:41

Monkeypox and legislation updates: Dr. Bill Morice

Answers from the Lab ·

2022/08/25

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the latest monkeypox developments, potential scenarios for monkeypox moving forward, and where the VALID Act stands.

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22:54

CIDP: Divyanshu (Div) Dubey, M.B.B.S.

Answers from the Lab ·

2022/08/23

(00:32) Would you mind telling our listeners a little about yourself and your background? (01:16) This evaluation is about CIDP — chronic inflammatory demyelinating polyneuropathy, correct? (02:16) Can you give us an overview of what the CIDP evaluation will consist of? (04:38) Our standalone test for neurofascin-155 won't change, but will be rolled into this new test along with contactin-1, correct? (06:41) This is a very rare disease with subtle clues, so does it make logical sense to

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13:03

Ongoing evolution of monkeypox: Dr. Bill Morice

Answers from the Lab ·

2022/08/18

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss how monkeypox can be transmitted, the possibilities of a future Emergency Use Authorization (EUA), and access to testing.

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8:26

PMND1: John Lieske, M.D.

Answers from the Lab ·

2022/08/16

(00:31) Could you tell us a bit about yourself and your background?(01:11) Could you describe these new tests and when it would be appropriate to use each of them in the clinic?(03:16) Could you provide a little background on why MCL is making changes to the PLA2R test?(04:34) Could you describe the change to KDIGO guidelines and when it may be appropriate to skip the biopsy? How will these new tests help physicians implement these new guidelines in their practices?

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10:49

Monkeypox testing progress: Dr. Bill Morice

Answers from the Lab ·

2022/08/11

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss new developments in monkeypox testing, updates on the federal response, and lessons learned from managing other viruses.

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19:38

Enhanced detection of genetic mutation to optimize...

Answers from the Lab ·

2022/08/09

(00:32) Could you please provide a bit about yourself and your background?(01:39) Could you please give a basic overview of the NPM1Q test and why we are so pleased to offer it?(06:56) Which patients should have this test and when should it be performed? Is it when they are initially diagnosed?(09:44) How would translocation 8;21 and inversion 16 tests be incorporated into testing for patients?(10:41) How are the results used in patient care?(13:41) What alternative tests options are

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14:55

Operationalizing monkeypox testing: John Osborn

Answers from the Lab ·

2022/08/04

John Osborn, operations administrator in the Department of Laboratory Medicine and Pathology at Mayo Clinic, joins the "Answers From the Lab" podcast for a discussion with host Bobbi Pritt, M.D. about monkeypox testing. In this episode, John and Dr. Pritt discuss how Mayo Clinic swiftly operationalized monkeypox testing and the challenges involved with supporting the new assay, including staffing.If the work discussed in the episode interests you, we’d love to have you join our team. If

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15:29

Nonradioactive assay helps diagnose heparin reaction:...

Answers from the Lab ·

2022/08/02

(01:51) Can you give a brief overview of the assay you developed and how it works?(06:28) The serotonin release assay is utilized within five to 14 days of heparin exposure. Is there a subsequent time when this test would be utilized?(10:28) How does this assay improve upon previous approaches?(12:58) Is there greater specificity and sensitivity with the use of nonradioactive materials?(13:46) What interesting findings have we had through the process of developing and validating this

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14:55

Monkeypox declared a global public health emergency:...

Answers from the Lab ·

2022/07/28

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the World Health Organization’s declaration of monkeypox as a global public health emergency, how Mayo Clinic Laboratories quickly implemented testing, and the public-private partnership to manage

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12:43

FDA-approved test expands options for Alzheimer's...

Answers from the Lab ·

2022/07/26

(00:32) Can you please tell our listeners a little about yourself and your background?(01:00) Mayo Clinic Laboratories already offers one test for Alzheimer's disease, right?(01:32) Could you tell our listeners about the new FDA-approved test that Mayo Clinic Laboratories will launch soon?(02:43) The test results will report the ratio of the amyloid isoforms, not the individual test components, right?(03:26) Does the new test require a certain tube?(04:15) Can you provide a little more

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9:16

Managing the current rise in COVID cases: Dr. Bill...

Answers from the Lab ·

2022/07/21

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the science behind the increasing COVID-19 infections, why individuals can get reinfected with different variants, and the effectiveness of the at-home antigen tests.

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12:33

Scaling monkeypox testing and the new COVID variant:...

Answers from the Lab ·

2022/07/14

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss advances in monkeypox testing, working with the CDC to scale testing and response efforts, the fast-spreading BA.5 variant of COVID-19, and how at-home testing affects the number of reported

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11:53

New SALSA bill and monkeypox testing at Mayo: Dr....

Answers from the Lab ·

2022/06/30

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the recent Department of Health and Human Services announcement that named Mayo Clinic Laboratories as one of five commercial labs to expand capacity for monkeypox testing. They also discuss newly

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14:24

The Latest on Monkeypox and Lab Legislation: Dr. Bill...

Answers from the Lab ·

2022/06/23

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss what the increasing monkeypox cases are revealing, and regulatory updates on the VALID Act and PAMA.

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10:03

The age of pandemics: Dr. Bill Morice

Answers from the Lab ·

2022/06/16

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the latest developments in monkeypox, the reality of living in the age of pandemics, and the importance of testing and public-private partnerships.

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11:25

WESDX: Cherisse Marcou, Ph.D., and Marissa Ellingson,...

Answers from the Lab ·

2022/06/14

(00:32):Before we jump in, would each of you share a little bit about your background and yourselves? (01:18):Dr. Marcou. could you provide us with an overview of what the WESDX test is? (01:50):Marissa, would you help explain why this test is important? (03:10):In your experience who would benefit from WESDX,(05:12):How does a provider order A WES DX and secondarily what type of samples are accepted?(06:24):What types of variants are detected by the test? (07:47):There are a lot of exome

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13:37

Monkeypox: Dr. Bill Morice

Answers from the Lab ·

2022/06/09

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice consider the recent uptick in cases of monkeypox and what labs can do to help facilitate accurate diagnosis of it and other viral infections.

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