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PODCAST

Springer Nature

Springer Nature

Welcome to the Springer Nature Soundcloud page! Here you will find several podcasts from our journals across a range of scientific subjects, including Gene Pod, ModPath Chat, Pediapod, Hereditypod and Brainpod.

science

All Episodes

00:11:38

Autonomic development in preterm infants is...

Springer Nature ·

2021/03/04

The latter half of gestation and early neonatal life are critical periods for the maturation of the autonomic nervous system. Premature infants are born with underdeveloped autonomic maturation and must undergo their developmental changes in a vastly different setting to the natural, in utero environment. A number of studies have shown autonomic dysmaturation in premature infants, although these have mainly looked at cohorts of children from high-morbidity NICUs. In this episode, Geoff Marsh talks

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00:09:35

Predictors of metastases in non-seminomatous TGCT

Springer Nature ·

2021/02/23

Pathological risk factors for metastatic disease in patients with testicular non-seminomatous germ cell tumors are debated. The tumor-node-metastasis (TNM) classification eighth edition for testicular cancers includes divergent versions, by the International Union Against Cancer (UICC) and by the American Joint Committee for Cancer (AJCC). In this episode we discuss with Dr. Daniel Berney his recent study on the topic. Associated article: https://www.nature.com/articles/s41379-020-00717-2

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00:17:24

Machine Learning-Based Algorithm to Predict Death...

Springer Nature ·

2021/02/23

Dr. Netto discusses with his two guests, Dr. Peter MCaffrey from the UTMB in Galveston and Dr. Adam Booth, their publication on developing a machine learning model using 5 serum chemistry laboratory parameters for the prediction of death from COVID-19. The discussion is followed by a conversation on the exciting role of AI and social media in Pathology given the unique expertise of the guests. Associated article: Development of a prognostic model for mortality in COVID-19 infection using machine

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00:22:32

Hereditypod - PopGroup 54 Special

Springer Nature ·

2021/02/23

In this episode we explore the 54th Population Genetics Group Meeting with two of its organisers: Prof. Andrea Betancourt and Eve Taylor-Cox (University of Liverpool). We also hear from the winner of the best student talk: Gabriela Montejo-Kovacevic (University of Cambridge). Listen now to hear about great new research and the trials of hosting an online conference.

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00:25:34

Hereditypod - The evolution of the sexes

Springer Nature ·

2021/02/23

Why did different sexes evolve? It’s a question as old as biology, but Prof. Dr Elvira Hörandl (University of Göttingen), with the help of biochemist Dr Franz Hadacek, may have discovered an important piece of the answer. Associated article: Oxygen, life forms, and the evolution of sexes in multicellular eukaryotes https://www.nature.com/articles/s41437-020-0317-9

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00:17:54

Hereditypod 2021 - Getting to know Heredity

Springer Nature ·

2021/02/23

In a bumper episode, filled with editorial expertise and top writing tips, discover why you should publish in Heredity in 2021!

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00:20:13

Hereditypod - The Best of 2020

Springer Nature ·

2021/02/23

Join host James Burgon as he shares his highlights from the past year of the Heredity Podcast.

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00:09:44

Brainpod 2021 - Acute dose-dependent effects of...

Springer Nature ·

2021/01/26

Interest is growing in the use of the psychedelic drug LSD for psychiatric research and even potentially for treatment. But placebo-controlled studies conducted to date have used just one dose of the drug—none have investigated the impacts of a variety of dosages within the same subjects. In addition, past studies did not use pharmaceutically-defined dosages of LSD, which has made verifying the effects of a particular dose difficult. To address this gap, Matthias Liechti, professor in the department

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00:11:00

Early pediatric chronic kidney disease is associated...

Springer Nature ·

2021/01/12

Pediatric chronic kidney disease (pCKD) results in a life-long burden that requires routine care. Neurocognitive dysfunction, specifically impairment on tasks of executive function, is a well-established comorbidity but there is a paucity of data exploring the neurobiology of these cognitive deficits. In this episode, we meet early career investigator, Dr Lyndsay Harshman, a pediatric nephrologist at the University of Iowa's Stead Family Children's hospital, who compared the brain morphometry

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00:05:53

Is newborn screening for metachromatic leukodystrophy...

Springer Nature ·

2021/01/12

While newborn screening is gradually expanding in many states in the U.S. and other countries to include some members of a class of diseases known as lysosomal storage diseases (LSD), there has yet to be a screening test available for one LSD called metachromatic leukodystrophy (MLD). MLD is a rare neurogenetic condition that is often fatal and there is currently no widely available approved treatment. However, there are a number of promising therapies under development in ongoing clinical trials

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00:10:56

Pediapod - Neonatal encephalopathy clinical trials:...

Springer Nature ·

2021/01/04

Therapeutic Hypothermia has long been the standard of care for infants with moderate to severe neonatal encephalopathy. However, the future of treatment for neonatal encephalopathy (NE) will focus on hypothermia adjuvant therapies. There needs to be a rethink in how future NE clinical trials are designed and analyzed, according to a multi-disciplinary expert panel who met at the 'Hypoxic-Ischemic Encephalopathy Symposium: Developing the Future'. In this episode we meet Dr. Kristen Benninger, a

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00:09:24

Pediatric pulmonary hypertension: insulin-like growth...

Springer Nature ·

2020/12/22

Pediatric Pulmonary Hypertension (PAH) is a heterogeneous disease, characterised by sustained elevation of pulmonary arterial pressures and death from right ventricular failure. Given the extremely high burden of morbidity and mortality associated with this disease, and the risk of the invasive procedures required for diagnostics, novel biomarkers for this disease would be beneficial. In this episode, we meet Early Career Investigator, Dr. Megan Griffiths from Johns Hopkins University, School of

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00:12:19

Rapid exome sequencing in PICU patients with...

Springer Nature ·

2020/12/22

Effective decision making in the Pediatric Intensive Care Unit relies on quickly ascertaining diagnostic information in order to deliver a tailored clinical response. The utility of rapid genetic testing of critically ill patients has been demonstrated several times, owing to their relatively high diagnostic yield. However the cost and slow turnaround of results have been major barriers in the past to the widespread uptake of this technology in the clinical setting. In this episode, we meet

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00:16:22

ModPath Chat - Kinase Fusion Related Thyroid Cancers

Springer Nature ·

2020/12/14

Dr. Peter Sadow , Director of Head and Neck Pathology at MGH discusses with Modern Pathology Editor Dr. George Netto his recent work defining morphologic correlates of the expanding list of Kinase Fusions driving thyroid cancers. A triage testing algorithm and therapeutic implications are highlighted in the discussion. Study by Chu et al, Clinicopathologic features of kinase fusion-related thyroid carcinomas: an integrative analysis with molecular characterization. Associated article:

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00:24:35

Hereditypod - Inspiring the Next Gen

Springer Nature ·

2020/12/14

When Jon Hale, a teacher at Beaulieu Convent School in Jersey, asked himself “how do we inspire the next generation of scientists?”, he came up with an incredibly ambitious plan. It involved a Royal Society Partnership Grant, daffodils, and some of the most cutting-edge genome sequencing technology available. In this episode Jon tells us about his transformative school-based initiative, and two of his students, Daisy (17) and Caitlin (17), explain how they took ownership over their first real

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00:23:30

Hereditypod - Plant Quantitative Genetics: from...

Springer Nature ·

2020/12/14

In this episode we discuss the new Heredity Special Issue, Plant Quantitative Genetics: from Theory into Practice, with guest editors Dr Alison Bentley (CIMMYT) and Dr Lindsey Compton (University of Birmingham). Join us as we delve into the reviews, perspectives and research papers that explore the opportunities and applications of quantitative genetics in a range of plant species, and one paper that asks the question: how can we inspire the next generation of plant scientists? Associated special

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00:14:32

Hereditypod - Are all lab mice the same?

Springer Nature ·

2020/12/14

For over a century, inbred mice have been at the heart of genetics research. They are undoubtedly one of the most important models in all of biology. But are the mice from inbred lines really as genetically identical as often assumed? Find out in this episode as we hear from Dr Jobran Chebib and Prof. Peter Keightley (University of Edinburgh). Associated article: Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site -

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00:05:09

Genepod - Elamipritide: A treatment for Barth syndrome

Springer Nature ·

2020/12/14

Barth syndrome, an exceedingly rare genetic condition that affects only males, causes heart disease and immune deficiencies–and there’s no known treatment that addresses the cause of the disease. On this month’s GenePod, Hilary Vernon, MD, PhD, associate professor of genetic medicine at Johns Hopkins University School of Medicine, describes a study of elamipretide, a compound already under clinical investigation that, based on its effectiveness in targeting mitochondria, she and her colleagues

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00:22:36

Pancreatic Cancer Genetics 2020

Springer Nature ·

2020/12/07

The recent publication of the “Pan-Cancer Atlas” by the Pan-Cancer Analysis of Whole Genomes Consortium provided a great opportunity for Dr. Ralph Hruban and his team to reflect on where we stand in our understanding of the genetics of pancreatic cancer. From germline variants that predispose to the development of the disease, to somatic mutations that are therapeutically targetable, genetics is now providing hope, where there once was no hope, for those diagnosed with pancreatic cancer. Associated

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00:16:22

ALK rearranged renal cell carcinoma (ALK-RCC)

Springer Nature ·

2020/12/07

The host discusses with Professor Ondrej Hes, from the Charles University in the Czech Republic, his recent multi-institutional study that further defines ALK-RCC as a genetically distinct renal cancer type showing a heterogeneous histomorphology. The authors advocate a routine ALK IHC screening for “unclassifiable RCCs” with heterogeneous features. Associated article: https://www.nature.com/articles/s41379-020-0578-0

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468 results

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