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PODCAST

Psychopharmacology and Psychiatry Updates

Psychopharmacology Institute

Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.

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All Episodes

10:13

The Serotonin Theory of Depression

Psychopharmacology and Psychiatry Updates ·

2023/01/12

In this episode, we discuss a recent systematic umbrella review of the evidence behind the serotonin theory of depression and the controversy this review has generated. We explore the evidence presented regarding the interplay between serotonin and depression and present concrete steps to address several concerns generated by the review. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 42 The Serotonin Theory of Depression: A

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09:50

SSRIs and Type 2 Diabetes in Children and Adolescents

Psychopharmacology and Psychiatry Updates ·

2023/01/07

Is there an association between SSRIs and type 2 diabetes in children and adolescents? In this episode, we discuss whether there is an association. We also explain whether there is an intraclass risk among different SSRIs. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Smart Take Vol. 02 SSRIs and Risk of Type 2 Diabetes in Children and Adolescents

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07:29

Tips for Treating Schizophrenia in Children and...

Psychopharmacology and Psychiatry Updates ·

2023/01/02

In this episode, we discuss additional clinical tips for treating schizophrenia in children and adolescents, including the considerations for selecting antipsychotics, recommendations for nonresponse, and when to use clozapine. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.5 CME: Psychosis and Schizophrenia in Children and Adolescents Additional Clinical Tips for Treating Schizophrenia In Children and Adolescents

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10:31

Physical Activity to Prevent Depression

Psychopharmacology and Psychiatry Updates ·

2022/12/28

In this episode, we review the current literature on the association between exercise and the risk for depression. Specifically, how much physical activity is associated with a lower risk for depression? We also discuss the World Health Organization recommendations for the ideal range of physical activity. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 41 Association Between Physical Activity and Risk of Depression: A

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19:38

Use of Antipsychotics for Treating Psychosis in...

Psychopharmacology and Psychiatry Updates ·

2022/12/23

In this episode, we discuss treatment options for managing psychosis and schizophrenia in children and adolescents, including the FDA-approved antipsychotics for this population. We also explain medication dosing guidelines and monitoring recommendations. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Psychosis and Schizophrenia in Children and Adolescents Treatment of Psychosis and Schizophrenia in Children and Adolescents:

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14:04

Depression in Adolescents

Psychopharmacology and Psychiatry Updates ·

2022/12/18

Are antidepressants in adolescent depression associated with an increased risk for suicidality? In this episode, we discuss the particularities of adolescent depression, including some statistics and the risk of suicide when using antidepressants in this population. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Smart Take Vol. 02 Depression in Adolescents

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15:21

Diagnostic Evaluation of Psychotic Symptoms in...

Psychopharmacology and Psychiatry Updates ·

2022/12/13

In this episode, we discuss the diagnosis of psychotic symptoms in children and adolescents, including the differences between primary and secondary psychosis and the rating scales for assessing these symptoms. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Psychosis and Schizophrenia in Children and Adolescents Diagnostic Evaluation of Psychotic Symptoms in Children and Adolescents

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10:04

Use of Folate and Its Derivatives in Depression

Psychopharmacology and Psychiatry Updates ·

2022/12/08

Can L-methylfolate help in depression treatment? Should we indicate it to all patients with depression? In this episode, we discuss the metabolic pathways for folic acid, when to indicate L-methylfolate, and when to perform genetic testing for methyltetrahydrofolate reductase (MTFR) enzymes. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 41 The Potential Use of Folate and Its Derivatives in Treating Psychiatric Disorders: A

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09:19

Antipsychotics and Cholinesterase Inhibitors for BPSD

Psychopharmacology and Psychiatry Updates ·

2022/12/03

Antipsychotics or cholinesterase inhibitors for BPSD? This episode discusses the evidence of antipsychotics and cholinesterase inhibitors for BPSD, including the risks of using antipsychotics in elderly patients. We also provide recommendations for treating patients with Parkinson’s disease and Lewy body dementia. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Antipsychotics

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11:57

SGAs in Youth With Bipolar Depression

Psychopharmacology and Psychiatry Updates ·

2022/11/28

What are the safest and most effective medications for depression in youth with bipolar disorder? In this episode, we compare the response rates of quetiapine, olanzapine, and lurasidone for bipolar depression in youth. This episode also explains the differences in metabolic side effects and discusses the limitations of this study. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Smart Take Vol. 01 Efficacy and Safety of SGAs in Youth

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07:47

Pharmacologic Treatments for BPSD

Psychopharmacology and Psychiatry Updates ·

2022/11/23

This episode discusses the pharmacologic treatments for BPSD, including the indications for using psychotropic medications as first-line treatment. It also explains when medications are ineffective and when to use them as a temporary measure. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Overview of Pharmacologic Treatment for BPSD

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10:42

Association Between FIASMA Psychotropics and COVID-19

Psychopharmacology and Psychiatry Updates ·

2022/11/18

What are FIASMA psychotropics? What do they have to do with COVID-19? In this episode, we discuss a recent study that compared rates of severe illness among patients who, when admitted for COVID-19, were or were not taking a FIASMA—a functional inhibitor of acid sphingomyelinase activity. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 40 Association Between FIASMA Psychotropic Medications and Reduced Risk of Intubation or

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08:24

Treatment Approaches for BPSD

Psychopharmacology and Psychiatry Updates ·

2022/11/13

Are antipsychotics the answer to the chaos of dementia? In this episode, we discuss the pharmacologic and nonpharmacologic treatment approaches to address BPSD, including the risks of using antipsychotics and the causes of death related to their use. Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Pharmacologic and Nonpharmacologic Treatment Approaches

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08:06

Brexpiprazole for Borderline Personality Disorder

Psychopharmacology and Psychiatry Updates ·

2022/11/08

In this episode, we discuss a recent RCT on using brexpiprazole to treat borderline personality disorder. Is it safe and effective? Could brexpiprazole be the magic bullet we were waiting for? Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 40 A Double-Blind Placebo-Controlled Study of Brexpiprazole for the Treatment of Borderline Personality Disorder

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11:29

Patient, Caregiver, and Environmental Factors...

Psychopharmacology and Psychiatry Updates ·

2022/11/03

This episode discusses the patient factors underlying BPSD, such as neurodegeneration, acute medical issues, medication changes, pain, and psychiatric diagnoses. It also explains caregiver and environmental factors and the concept of the “broken brain.” Faculty: Lauren Gerlach, D.O. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Management of Behavioral and Psychological Symptoms of Dementia Understanding Patient, Caregiver, and Enviromental Factors

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09:59

Long-Term Treatment With Methylphenidate in Preschool...

Psychopharmacology and Psychiatry Updates ·

2022/10/29

Is it safe to use stimulants in preschool children with ADHD? In this episode, we discuss the long-term symptom control and safety of an ER methylphenidate compound in preschool children 4 to <6 years. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Smart Take Vol. 1 Long-Term Treatment With Extended-Release Methylphenidate Treatment in Younger Children

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18:37

Use of Psychotropics in Patients With Hepatic Issues

Psychopharmacology and Psychiatry Updates ·

2022/10/24

How to determine whether hepatic impairment can affect drug metabolism? This episode discusses practical considerations when prescribing psychotropic medications for patients with hepatic issues. It also clarifies dosing considerations for specific medications, such as clozapine and valproate, in the context of patients with hepatic issues. Guest: Jonathan Meyer, M.D. Interviewer: Mohan Gautam, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Use of

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15:03

Important Considerations for Switching to Clozapine

Psychopharmacology and Psychiatry Updates ·

2022/10/19

How to titrate clozapine in inpatients and outpatients? In this episode, we discuss important considerations for switching to clozapine, including the indications and clinical scenarios for using it. This episode also explains precautions while titrating clozapine and how to reduce the preswitch antipsychotic. Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Antipsychotic Switching: Intersection of Art and Science Important Considerations

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09:02

Pharmacologic and Psychosocial Interventions for...

Psychopharmacology and Psychiatry Updates ·

2022/10/14

In this episode, we discuss the interventions found to be efficacious in youth with ADHD. Specifically, would treatment with stimulants be effective at reducing irritability in youth with ADHD? Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CMEs: Quick Take Vol. 39 A Mini-Review of Pharmacologic and Psychosocial Interventions for Reducing Irritability Among Youth With ADHD

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12:22

Switching From Oral Antipsychotics to LAIs

Psychopharmacology and Psychiatry Updates ·

2022/10/09

This episode discusses antipsychotic switching from oral antipsychotics to LAIs, including the factors to consider when titrating antipsychotics and establishing PO tolerability before switching to an LAI. Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Antipsychotic Switching: Intersection of Art and Science Types of Antipsychotic Switching: Between PO Agents and From PO to LAI

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