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PODCAST

OncoPharm

OncoPharm is a podcast dedicated to all things oncology pharmacy. Most episodes cover updates and recent publications concerning the use of medications in caring for patients with cancer. Periodically, episodes drop devoted to Landmark Clinical Trials in oncology and Fundamentals of Oncology Pharmacy.

science

All Episodes

00:16:32

Adjuvant Abemaciclib

OncoPharm ·

2021/10/14

FDA approves 2-years of abemaciclib plus endocrine therapy for high-risk HR+, HER2(-) patients. Quite a bit to discuss about this. Also, FDA expands indications for pembrolizumab (of course) and brexucabtagene autoleucel. NOTE: A 5cm breast tumor is a T3 lesion, not a T2 as misstated in this episode.

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00:18:06

Same Day Pegfilgrastim

OncoPharm ·

2021/10/07

Dr. Ali McBride joins the Pod to spar over same-day vs. next-day pegfilgrastim. (There is some audio feedback early in the Pod that we clean up after a few minutes. Apologies!) Bibliography: Burris et al: https://pubmed.ncbi.nlm.nih.gov/20808556/ AOC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819939/ McBride et al (CHOP): https://www.futuremedicine.com/doi/10.2217/fon-2021-0532 McBride et al (NHL): https://doi.org/10.18553/jmcp.2021.21010

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00:12:41

Sarcomas In A Nutshell

OncoPharm ·

2021/09/30

An oversimplified approach to thinking about sarcomas.

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00:23:09

ESMO21 & New Drugs (Cervical Ca Focus)

OncoPharm ·

2021/09/23

Lots to discuss from ESMO 2021 to new drug approvals. First, we discuss the updates in cervical cancer from ESMO (pembrolizumab with chemo) and the newly approved tisotumab-vedotin. Then, we discuss another new agent, mobocertinib and its scary QT prolongation profile as well as cabo-confusion in thyroid cancer. Finally, we discuss the potentially practice changing, but preliminary, data from ESMO in bladder cancer (VESPER) and HER2+ MBC (DESTINY-Breast03).

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00:12:30

CASSIOPEIA Part 2

OncoPharm ·

2021/09/16

Discussing the updated results after the 2nd randomization of CASSIOPEIA looking at daratumumab maintenance following ASCT. Link: https://doi.org/10.1016/S1470-2045(21)00490-3

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00:16:52

MMF For ITP

OncoPharm ·

2021/09/09

Discussing the use of mycophenolate mofetil (MMF) for ITP (https://www.nejm.org/doi/full/10.1056/NEJMoa2100596) as well as regulatory updates on atezolizumab and zanubrutinib.

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00:10:25

Hypercalcemia Of Malignancy (in Under 10)

OncoPharm ·

2021/09/02

Foundations of OncoPharm: Hypercalcemia of Malignancy (in under 10 minutes)

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00:16:30

Belzutifan and Recent Updates

OncoPharm ·

2021/08/26

Belzutifan, the 1st hypoxia-inducible factor (HIF) inhibitor is FDA-approved. Plus, expanded indication approvals for nivolumab, dostarlimab, lenvatinib/pembrolizumab, & Ivosidenib. Finally, my Top 5 Rolling Stones Songs (14:30).

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00:12:03

Booster COVID-19 Vaccinations in Immunocompromised...

OncoPharm ·

2021/08/19

Looking into the data behind the FDA & CDC's allowance for a booster mRNA vaccine for immunocompromised patients.

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00:08:12

Sneaky TKI Toxicities

OncoPharm ·

2021/08/12

A recent patient experience serves as a reminder than TKIs, like cabozantinib, can produce many "minor" toxicities that can really add up and affect QOL.

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00:11:59

Acala V. Ibrutinib(again) & VidazaAllo

OncoPharm ·

2021/08/05

Two recent publications to discuss: 1. The publication of a study discussed on our ASCO '21 Pod on acalabrutinib vs. ibrutinib and patient implications (https://ascopubs.org/doi/pdf/10.1200/JCO.21.01210) 2. A good illustration of the "crossing of the curves" and interpreting Kaplan-Meier curves using alloHSCT vs. 5-aza in MDS patients. https://ascopubs.org/doi/pdf/10.1200/JCO.20.02724

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00:15:11

Breast Cancer & cGVHD Updates

OncoPharm ·

2021/07/29

Two breast cancer updates (pembrolizumab in TNBC and adjuvant AI duration) and two cGVHD updates (belumosudil and ruxolitinib).

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00:12:07

GOG-172 (IP chemotherapy in ovarian cancer)

OncoPharm ·

2021/07/22

The almost-award winning* Landmarks in OncoPharm series returns to discuss the landmark Armstrong et al 2006 NEJM paper on using intraperitoneal chemotherapy in stage III ovarian cancer. Link: https://www.nejm.org/doi/full/10.1056/nejmoa052985 *not really

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00:09:00

Advertising Amateur Hour

OncoPharm ·

2021/07/15

A case study in misbranding promotional materials and how to help FDA regulate them.

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00:17:03

Capecitabine

OncoPharm ·

2021/07/08

Foundations of OncoPharm: capecitabine

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00:12:19

Hormonal Toxicity Management In Breast Cancer Pts

OncoPharm ·

2021/07/01

A foundational topic in oncology - managing toxicities of tamoxifen and AI's in breast cancer patients. An excellent evidence-based review was recently published, and is worth our time on the Pod. Link: https://doi.org/10.1016/S1470-2045(20)30666-5

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00:12:44

EA1131 & TOURMALINE

OncoPharm ·

2021/06/24

So-called negative trials still offer information. We discuss ECOG-ACRIN EA1131 in breast cancer and TOURMALINE-MM1 in myeloma in this epidose. EA1131: https://ascopubs.org/doi/pdf/10.1200/JCO.21.00976 TOURMALINE-MM1 (final OS analysis): https://ascopubs.org/doi/pdf/10.1200/JCO.21.00972

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00:26:31

Why Learning Oncology Is Hard

OncoPharm ·

2021/06/18

Why is learning oncology so hard? To get the students perspective I ask a few pharmacy students why in hopes of learning how to better teach and precept oncology trainees.

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00:28:18

ASCO 2021

OncoPharm ·

2021/06/10

Highlighting results presented at ASCO's 2021 annual meeting.

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00:14:18

Sotorasib, Infigratinib, And More

OncoPharm ·

2021/06/03

Two new drugs approved in the last week: 1. sotorasib, a drug for a specific KRAS mutation (G12C) in 2nd line metastatic NSCLC 2. infigratinib, basically a "me too" FGFR inhibitor approved for metastatic cholangiocarcinoma We all discuss the latest adjuvant CHECKMATE study (nivolumab in urothelial carcinoma) and a recent study of seropositivity in cancer patients following COVID vaccination.

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423 results

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