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PODCAST

This Week in Microbiology

Vincent Racaniello

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows "This Week in Virology" (TWiV) and "This Week in Parasitism" (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

science life sciences

All Episodes

01:11:45

TWiM #110: Exploring unseen life with unpronounceable...

This Week in Microbiology ·

2015/08/19

The TWiM team focuses on the gut microbiome, from a single member, Akkermansia muciniphila, to the effect of antibiotics on its composition and colonization resistance against C. difficile. Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Links for this episode Agar art contest Akkermansia muciniphilia and obesity (Gut) A. muciniphilia genome (Biol Direct) Alterations of gut microbiota and C. difficile

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01:08:52

TWiM #109: Precision killing

This Week in Microbiology ·

2015/08/06

The TWiM cohort discusses the use of antimicrobial peptides to target specific bacteria in the microbiome, and how the intracellular bacterium Wolbachia selectively kills male hosts. Links for this episode: Antimicrobial peptides to modulate microbial ecology (PNAS) Targeting specific bacteria in the oral microbiome (Trends Micro) How Wolbachiakills male hosts (PLoS Biol) Wolbachia phage on TWiV 332 Image: Transmission electron micrograph of Wolbachia within an insect cell. By: Scott

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01:12:13

TWiM #108: Vaccine in the time of cholera

This Week in Microbiology ·

2015/07/23

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson. The professors of TWiM discuss a University of Wisconsin plan for rescuing biomedical research in the US, and results of a clinical trial in Bangladesh of an oral cholera vaccine. Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Links for this episode Rescuing biomedical research (eLife) Rethinking graduate and postdoc

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01:31:06

TWiM #107: The battle in your bladder

This Week in Microbiology ·

2015/07/09

Hosts: Vincent Racaniello and Michael Schmidt. Vincent and Michael discuss the highly diverse microbiome of uncontacted Amerindians, and how the composition of human urine plays a role in the battle for iron. Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app. Links for this episode Microbiome of uncontacted Amerindians (Sci Adv) Urinary composition controls siderocalin activity (J Biol Chem) Urine acidity and UTI

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01:16:32

TWiM #106: Lawn mower disease

This Week in Microbiology ·

2015/06/24

Vincent and Michael speak with Katy Bosio about her research on pathogenesis, immunity, and vaccines against Franciscella tularensis, the causative agent of tularemia.

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57:54

TWiM #105: Real bugs with legs

This Week in Microbiology ·

2015/06/05

The TWiM team reviews the microbiological safety of herbs in the United Kingdom, and how a peptide from the milkweek bug binds the ribosome and inhibits bacterial protein synthesis. Links for this episode: Microbes in whole-leaf herbs (J Appl Micro) Antimicrobial peptide blocks ribosome (Nat Struct Mol Biol) Bacterial protein synthesis (Micro Mol Biol Rev) Antimicrobial peptides (Nature) The battle for tryptophan (Front Cell Infect Micro) Image credit

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01:03:49

TWiM #104: Feed me polyamines, biofilm

This Week in Microbiology ·

2015/05/21

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson. The TWiM team discusses how measles vaccination protects against other infectious diseases, and links between bacterial biofilms and colon cancer. Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Links for this episode Measles vaccination prevents all-cause infectious disease (Science) Master of contagion (The Loom) Video: Measles

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01:05:50

TWiM #103: The battle for iron

This Week in Microbiology ·

2015/05/08

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson. The TWiM team is amazed by the ocelloid, and an evolutionary battle for iron between mammalian transferrin and bacterial transferrin-binding protein. Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Links for this episode A unicellular camera-type eye structure (PLoS One) Escape from iron piracy (Science) Iron in infection and

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57:43

TWiM #102: Happiness is the spore-formers in your gut

This Week in Microbiology ·

2015/04/24

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson. The TWiM team discusses evidence that serotonin synthesis is regulated by spore-forming members of the gut microbiota. Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app. Links for this episode When antibiotic resistance in vitro falls short (STC) Gut microbiota control serotonin in mice (Cell) Serotonin biosynthesis (Wikipedia) Microbial

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01:14:44

TWiM #101: The MRSA in your home

This Week in Microbiology ·

2015/04/01

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson. The TWiMers discuss how aroma helps disperse yeast cells on insect vectors, and evidence that MRSA is transmitted within households. Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app. Links for this episode Aroma promotes yeast dispersal on flies (Cell Rep) MRSA is transmitted within households (mBio) FAQ: The threat of MRSA (AAM) Image

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50:38

TWiM #100: Omnis cellula e cellula

This Week in Microbiology ·

2015/03/18

Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Jo Handelsman. The TWiM team celebrates 100 episodes with a Talmudic question, and discussion of how a single mutation alters bacterial host tropism. Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app. Links for this episode A single mutation alters bacterial tropism (Nat Gen) Talmudic question #104 (Small Things Considered) Principles of Microbial Diversity (ASM

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01:01:56

TWiM #99: Careers in Biodefense

This Week in Microbiology ·

2015/03/04

Hosts: Vincent Racaniello Guests: Maria Julia Marinissen, Edward H. You, and David R. Howell Vincent meets up with Maria, Edward, and David at the ASM Biodefense and Emerging Infections Research meeting to talk about alternative careers for scientists. Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app. A video version of this episode is available at microbeworld.org/twim Links for this episode: ASM Biodefense meeting FBI

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58:37

TWiM #98: Bacteria and eukaryotes get horizontal

This Week in Microbiology ·

2015/02/19

The TWiM crew ponders the question of how a bacterium finds its middle when dividing, then divulge the transfer of interbacterial antagonism genes to eukaryotes, where they may function in innate defense. Links for this episode: Size independent symmetric division (Nat Commun) How does a bacterium find its middle? (Nat Struct Biol) Genes transferred from bacteria augment eukaryotic defenses (Cell) Antibacterial gene transfer (eLife) Letters read on TWiM #98 on TWiM 98 Visit

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01:14:23

TWiM #97: There’s gold in them hills

This Week in Microbiology ·

2015/02/04

The TWiM team reveal how bacteria in a shipworm’s gills help digest wood in the gut, and an approach that identifies a new antibiotic from the soil. Links for this episode: Gill bacteria enable a novel digestive strategy (PNAS) Killing bacteria without resistance (Nature) An irresistable newcomer (Nature) Peptidoglycan synthesis animation 10 x 20 initiative (IDSA) Longitude Prize Visit microbeworld.org/twim for more.

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54:39

TWiM #96: A lean, mean sequencing machine

This Week in Microbiology ·

2015/01/21

Hosts: Vincent Racaniello. Special guest: Rob Knight Vincent meets up with Rob Knight to talk about the technology that has fueled his drive to sequence the Earth and its inhabitants. Check out the Microbeworld app. Links for this episode Microbes en masse (Nature) Obesity alters gut microbial ecology (PNAS) Sharing microbiome with dogs (eLife) Earth microbiome project (BMC Biology) Stability of gut micobiota (Science) Gut microbes and the brain (J Neurosci) Send your microbiology questions

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01:06:22

TWiM #95: A microbe lover in San Diego

This Week in Microbiology ·

2015/01/09

Hosts: Vincent Racaniello. Special guest: Stanley Maloy Vincent meets up with Stan Maloy on the campus of San Diego State University to talk about his career in microbiology and his work as Dean of Science. Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app. Links for this episode: Maloy lab Salmonella.org Microbial genetics course page Typhoid Mary Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv,

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01:06:50

TWiM #94: Nitrochondria

This Week in Microbiology ·

2014/12/25

Vincent, Elio, and Michael discuss a symbiosis between a nitrogen-fixing cyanobacteria and a single-celled eukaryotic alga. Links for this episode: Unicellular cyanobacterium and alga symbiosis (Science) Diversity of nitrogen-fixing cyanobacterium and its host (Environ Micro) Talmudic Question #4 (answer) Talmudic Question #2 Coccolithophore (Wikipedia) Visit microbeworld.org/twim to view the complete shownotes and entire back catalog.

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56:30

TWiM #93: Worming in on bacteria

This Week in Microbiology ·

2014/12/11

Vincent, Elio, and Michael reveal that a soil-dwelling nematode can recognize and respond to a bacterial quorum sensing molecule through a sensory neuron.

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01:08:06

TWiM #92: Flying biofilms

This Week in Microbiology ·

2014/11/27

Vincent, Elio, Michael and Michele discuss the possible eradication of wild poliovirus type 3, and how microsporidian parasites prevent locust swarming behavior.

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58:32

TWiM #91: Rats, viruses, and bacteria

This Week in Microbiology ·

2014/11/14

Vincent, Elio, and Michele review a study of the viruses and bacteria in commensal rats in New York City. Visit microbeworld.org/twim for complete show notes. Thanks for listening!

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