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PODCAST

The Drug Discovery World Podcast

Drug Discovery World (DDW)

Here at Drug Discovery World (DDW) we"ve been publishing articles written by leading experts in the Drug Discovery, Pharmaceutical, and BioPharmaceutical industries for over 20 years. DDW has grown as a quarterly business review of drug discovery and development, and now we"ve created this podcast to allow you to listen to our articles on the go. In our journal and this podcast, we cover topics surrounding: drug discovery; drug development; business; chemistry; enabling technologies; informatics;

science life sciences

All Episodes

36:30

Clinical trials and the growing importance of technology

The Drug Discovery World Podcast ·

2022/01/05

Medidata technology has helped to bring COVID-19 vaccines and treatments to market in record timelines and the company was the first to have launched a fully end-to-end Decentralised Clinical Trials (DCT) offering. Decentralised clinical trials, described as the ‘new normal’ and the future of clinical research, harness remote technologies to enable patients to participate in clinical trials from their home or preferred location, decreasing patient burden and offering greater flexibility as well as

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25:03

Therapeutics: Changing the way we treat disease

The Drug Discovery World Podcast ·

2021/12/23

The latest free-to-listen DDW podcast episode is titled “Therapeutics: Changing the way we treat disease”. It covers two articles written for Volume 22, Issue 2 – Spring 2021 of the Drug Discovery World Magazine and has been narrated by DDW’s Megan Thomas. These articles are titled: “Avoiding double strand breaks on the CRISPR path to therapeutic discovery” and “The power of precision medicine”. In the first article, Nicola McCarthy from Horizon Discovery explains: Now a key pillar in the

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33:34

Using biotechnology to maximise drug discovery output

The Drug Discovery World Podcast ·

2021/12/17

High-throughput screens are a recognised hit-finding process but the use of an integrated discipline approach is key to maximising the output from such a screening methodology. In the first article, Ian Linney and Scott Maidment from Charles River describe the value of integration of medicinal chemistry in this method. Thanks to continued advances in genetic engineering, investigators often find they can obtain the most relevant mouse model for their research by commissioning the custom

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39:41

Building on current drug discovery methods

The Drug Discovery World Podcast ·

2021/11/26

The articles are called “The new synthesis: How synthetic DNA technology is changing drug discovery” and “In vitro drug interaction data critical in drug repurposing”. The first was written by Dr Tim Brears, CEO of Evonetix and Dr Raquel Sanches-Kuiper, Director of Biology at Evonetix. The second was written by Madison Knapp, Marketing Communications Specialist, and Dr. Brian Ogilvie, Vice President of Scientific Consulting, at SEKISUI XenoTech. In “The new synthesis: How synthetic DNA technology is

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26:10

Analysing the technology driving innovation in drug...

The Drug Discovery World Podcast ·

2021/11/05

In the first article, DDW Editor Lu Rahman takes look at some of the latest imaging innovations available and how it can benefit drug target identification and drug discovery research. In the second, Farah Patell-Socha, PhD, VP Research Products tells Lu Rahman about some of the company’s groundbreaking work in this field and the benefits it is creating for disease modelling and drug discovery.

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27:18

The important role that antibodies play in drug...

The Drug Discovery World Podcast ·

2021/10/25

The latest free-to-listen DDW podcast episode covers two articles written for Volume 22, Issue 2 – Spring 2021 of the Drug Discovery World Magazine, narrated by DDW’s Megan Thomas. These articles are titled: “Antibody therapeutics: the other race for immunity against SARS-CoV2” and “Synthesising new solutions for small molecule antibodies”. In the first article, Sophie Lutter, OXGENE, looks at the important role antibody therapeutics have to play and how, as the world has looked for Covid-19

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23:40

Enhancing the role of multiplexing in high-throughput...

The Drug Discovery World Podcast ·

2021/10/15

Among the topics Lu Rahman will be discussing with Wylie will be the key challenges scientists face with biomarker and drug discovery and how high-throughput screening can help alleviate this. High throughput with multiplex is valuable for drug discovery and Wylie will provide insight on this as well offering expert opinion on the future of multiplex immunoassays in drug and biomarker discovery. Tune in to hear what critical factors Wylie believes researchers should consider when choosing an assay

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22:14

The Bamlanivimab story - how it reached clinic in...

The Drug Discovery World Podcast ·

2021/10/08

Bamlanivimab was the first neutralising monoclonal antibody to receive emergency use authorisation from the FDA as a treatment for mild to moderate COVID-19 on 9 November 2020, 94 days after the monoclonal antibody discovery workflow began for the molecule. This achievement, says Eli Lilly, represents the shortest timeline from discovery to public usage for a monoclonal antibody to date. In February 2021, bamlanivimab administered with etesevimab received emergency use authorisation for treatment of

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40:50

Recipe for success: collaboration in drug discovery

The Drug Discovery World Podcast ·

2021/10/06

The latest free-to-listen DDW podcast episode is titled “Recipe for success: collaboration in drug discovery”. It covers three articles: “Why collaboration matters and how to make it a success”; “Platform biotechnologies and the art of collaboration”; and “Cell painting: a vibrant future for phenotypic drug discovery”. In the first article, Matthew A. Clark, Chief Executive Officer, X-Chem, spoke to Lu Rahman about the company’s experience of collaboration and how it enables innovation,

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28:58

Opportunities to improve drug discovery systems

The Drug Discovery World Podcast ·

2021/09/21

This is the latest episode of the free DDW podcast: “Opportunities to improve drug discovery systems”. It covers two articles written for Volume 22, Issue 1 – Winter 2020/21 of the Drug Discovery World Magazine. The first article is titled “Precision control of protein release to reconfigure bioprocessing and cell-based assays”, where the authors Dr J. Mark Treherne, Dr Christian Pernstich and Dr Michael Jones examine how the controlled release of proteins will improve the reproducibility of

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33:53

Putting virology back on the map: the fight against...

The Drug Discovery World Podcast ·

2021/09/07

This is the latest episode of the free DDW podcast, “Putting virology back on the map: the fight against Covid-19”. It covers two articles written for Volume 22, Issue 1 – Winter 2020/21 of the Drug Discovery World Magazine. The first article is a case study titled “New technology in COVID research may accelerate vaccines”, and the second is called “Virus in a well – microplate-based assays for virology research”. The first covers the technological advancements required to understand

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29:01

The benefits of robust colony management in drug...

The Drug Discovery World Podcast ·

2021/09/01

John Couse, Vice President of Scientific Services at Taconic Biosciences discusses the benefits of a robust colony management solution/partner in the drug discovery success; how it can enable companies to scale through resource management and create efficiencies. Couse has extensive knowledge of colony managements solutions and outlines the benefits they create for drug discovery researchers in terms of boosting efficiencies and achieving savings. He discusses barriers to uptake and how they can be

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09:45

Automating the cell culture workflow

The Drug Discovery World Podcast ·

2021/09/01

In this podcast Dr. Joanna Hawryluk discusses automating the cell culture workflow and explains the importance of cell culture workflow in the drug discovery process and how it can be improved thanks to technological advances. Hawryluk talks us through the cell culture workflow and its relevance within the drug discovery process focussing on the areas that hold particular importance for this process. She also shares her expertise on how important sample preparation is for downstream experimental

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23:00

Streamlining gene therapy and how MS provides...

The Drug Discovery World Podcast ·

2021/08/17

This episode covers two narrated articles written for DDW and is read aloud by Megan Thomas, both of which were published in Volume 22, Issue 1 – Winter 2020/21 of Drug Discovery World. The first article is titled, “Streamlining gene therapy manufacturing will help products reach more patients”, and was written by Akash Bhattacharya, the Senior Application Scientist at Beckman Coulter Life Sciences. The second article is titled, “It’s all in the technique: how MS provides information on virus

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20:45

A model for successful pharma and vendor engagement

The Drug Discovery World Podcast ·

2021/08/05

Digital transformations are having wide-ranging and profound impacts within life sciences, creating both opportunities and challenges. One of those challenges is adopting new software systems to drive the transformations. A team from Novartis Institutes of BioMedical Research (NIBR) recognised the need to ensure a good user experience for their in vivo study support groups. The NIBR team, partnered with technology provider, RockStep Solutions (RSS), to tackle the challenge. In this article, the

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35:04

Paving the way for optimum drug discovery

The Drug Discovery World Podcast ·

2021/07/23

This is the latest episode of the free DDW podcast, “Paving the way for optimum drug discovery”. It covers two narrated articles written for Volume 22, Issue 1 – Winter 2020/21 Of DDW and they are read aloud by Megan Thomas. These articles are titled: “In vitro models for assessing drug toxicity: new approaches and development” and “Accelerating assay development optimisation for drug discovery”. In the first article, Karissa Cottier, PhD Research Scientist, BioIVT, ADME-Tox, examines the ongoing

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15:23

Antibody engineering: the importance of collaboration...

The Drug Discovery World Podcast ·

2021/07/16

Mathur talks about Twist’s antibody expertise, drawing on the company’s experience and looking at the importance of collaboration. The company has created some successful partnerships and she explains what these look like, why they have been fruitful, and how they have enabled Twist to use its capabilities to maximum effect. Listen now to hear Mathur discuss the company philosophy, how the pandemic has affected the business, its partnership experience and what the future holds for this

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15:26

Comparing SDS-PAGE with automated CE-SDS for improved...

The Drug Discovery World Podcast ·

2021/07/05

Aydogdu talks us through how the accurate and quantitative analysis of product purity is a fundamental component of effective development of a biotherapeutic protein. But without consistent techniques and high-quality, reproducible results, it is difficult to precisely assess the product’s efficacy and/or safety, potentially delaying, even jeopardising, its approval. He also reveals how Bio-Techne overcame this issue for a particular customer.

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15:15

The importance of proteogenomics in drug discovery...

The Drug Discovery World Podcast ·

2021/06/07

Mälarstig is currently responsible for developing and applying strategies for new drug targets and precision medicine. He has extensive experience working in international academic consortia and public–private partnerships such as the SCALLOP consortium. In this podcast he outlines the role of pQTLs in the drug discovery process and the growing importance of proteogenomics. In this podcast, hear Mälarstig discuss proteogenomics, an emerging approach that aims to advance basic, translational and

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16:23

Precision medicine in the era of artificial intelligence

The Drug Discovery World Podcast ·

2021/05/20

The latest episode of the free DDW podcast, “Precision medicine in the era of artificial intelligence”, covers one narrated article of the same title written for DDW and read aloud by Megan Thomas. It was written by Dr Lofti Chouchane and Dr Javaid Sheikh. Dr Chouchane is a professor in the departments of genetic medicine, and microbiology and immunology at Weill Cornell Medicine-Qatar. Dr Sheikh is the Dean of Weill Cornell Medicine-Qatar. The two doctors discuss the value of biobanks, artificial

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318 results

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