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PODCAST

The Drug Discovery World Podcast

Drug Discovery World (DDW)

Here at Drug Discovery World (DDW) we"ve been publishing articles written by leading experts in the Drug Discovery, Pharmaceutical, and BioPharmaceutical industries for over 20 years. DDW has grown as a quarterly business review of drug discovery and development, and now we"ve created this podcast to allow you to listen to our articles on the go. In our journal and this podcast, we cover topics surrounding: drug discovery; drug development; business; chemistry; enabling technologies; informatics;

science life sciences

All Episodes

30:12

What has the pandemic taught us about clinical trials?

The Drug Discovery World Podcast ·

2021/04/30

The latest DDW Sitting Down With podcast features Raj Indupuri, CEO of eClinical Solutions and he talks to us about clinical trials. Listen to find out why Idupuri believes ‘data is the new fuel that will drive human progress’, the effect of Covid-19 on clinical trials and what the sector can learn from the pandemic to make it better prepared for any future similar situations.

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25:16

Advances in cell and protein analysis for virology...

The Drug Discovery World Podcast ·

2021/04/14

This DDW podcast features Dr Hongshan Li, Applications Manager, Sartorius, discussing advances in cell and protein analysis for virology research. This episode examines virology research - what’s currently happening in the sector and how new advances in technology are helping push forward innovation and drug development. With COVID-19 playing such a significant role in the drug discovery and development industry over the last year, we find out what effect it has had and Dr Li explains how we can

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17:13

Flow Cytometry in Drug Discovery

The Drug Discovery World Podcast ·

2021/04/13

This narrated article is called “Why flow cytometry in drug discovery is a real life-saver”, in which Roy, Global Product Manager at Miltenyi Biotec, outlines the benefits of flow cytometry, offering case study examples for its use. Capable of boasting high-throughput, accurate, multiparameter and highly reproducible results, it’s time for drug discovery industries to look again at how flow cytometry can be successfully utilised within challenging processes.

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22:22

Vaccine innovation in the age of Covid-19

The Drug Discovery World Podcast ·

2021/03/31

This is the latest episode of the free DDW podcast, titled Vaccine innovation in the age of Covid-19. It covers two narrated articles written for DDW and read aloud by Megan Thomas. These articles are titled: “Vaccine innovation in the age of Covid-19 & beyond” and “Creating vaccines: Why we should be celebrating the life of the researcher”. The first narrated article is a discussion between Dr Sanjay Garg and Dr Anis H Khimani about key learnings and best practices during Covid-19 vaccine research

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15:33

With vaccines taking centre stage how critical is the...

The Drug Discovery World Podcast ·

2021/03/02

This DDW Sitting Down With episode features Guy Goldberg, Chief Business Officer of RedHill Biopharma. In this episode - With vaccines taking centre stage how critical is the part therapeutics have to play in the pandemic? - Goldberg talks us through Covid-19 therapeutics and their role in the pandemic. Goldberg shares his market insight, the benefits of an orally-administered small molecule tablet for COVID treatment and how the company has maintained its success in the therapeutics market.

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23:38

The potential of metabolomics & COVID-19 Vaccine...

The Drug Discovery World Podcast ·

2021/02/23

Today's episode is titled The potential of metabolomics & COVID-19 Vaccine Development, and covers 2 articles taken from the most recent Fall issue of DDW. These articles are titled: Why metabolomics has the potential to transform diagnosis and treatment. & COVID-19 Vaccine Development: dethroning evil King Coronovirus These articles were firstly based on an interview with key members of metabolon, and the second article was written by Laural Barchas, Senior Technical Writer, Takara Bio. For more

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27:38

The power of precision and the potential of human...

The Drug Discovery World Podcast ·

2021/02/09

Today's episode is titled: The power of precision and the potential of human tissue chips, and covers 2 articles taken from the most recent issue of DDW. These articles are titled: The power of precision to keep biologics effective and safe & Why we should be interested in human tissue chips These articles were written by Dr Mark Lies, Global Business Manager of Capillary Electrophoresis, SCIEX, and Dr. Kacey Ronaldson-Bouchard For more information on Drug Discovery World, head to:

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35:37

The Business Side of Drug Discovery

The Drug Discovery World Podcast ·

2021/01/26

Today's episode on the topic of The Business Side of Drug Discovery, covers 3 articles taken from the most recent Fall issue of DDW. These articles are titled: Building the foundations for post COVID-19 R&D, Opportunity Knocks: Why compound screening libraries are worth the investment, and How to achieve data driven R&D at speed These articles were written by multiple authors. For more information on Drug Discovery World, head to: https://www.ddw-online.com

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26:36

Innovation and Opportunity in Drug Discovery

The Drug Discovery World Podcast ·

2021/01/12

Today's episode on the topic of Innovation and Opportunity in Drug Discovery, covers 3 articles taken from the most recent Fall issue of DDW. These articles are titled: Japanese drug development: Where is the innovation, Where are the opportunities in global drug discovery, and New for Old: The value behind drug repurposing. These articles were written by Lu Rahman, editor at Drug Discovery World For more information on Drug Discovery World, head to: https://www.ddw-online.com

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28:50

2030 Life Sciences and Health in the Digital Age...

The Drug Discovery World Podcast ·

2020/12/22

The Pistoia Alliance has developed a research paper which sets out to consider what the life science, biopharma R&D and healthcare ecosystem might look like in 2030, in particular how the increasing adoption and sophistication of technology will affect companies and patients alike. This article is the second part of a two-part series based on that paper. Written in retrospect from the world as it is in 2030, it looks at how healthcare has changed in the intervening decade. If you'd like to view the

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34:09

2030 Life Sciences and Health in the Digital Age...

The Drug Discovery World Podcast ·

2020/12/08

This article is the first in a two-part series based on The Pistoia Alliance report. Written in retrospect from the world as it is in 2030, it looks at how healthcare has changed in the intervening decade, covering the socio-economic and political evolutions that have happened, the subsequent effects on population health and the innovative technologies which have had the greatest impact. The intention of this 2030 report is to stimulate debate as to what the future may hold, and to identify the key

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24:01

Evolution of User Experience for life sciences

The Drug Discovery World Podcast ·

2020/11/24

Since 2017 we have seen the slow and steady adoption of User Experience (UX) within the life sciences. User Experience is an evidence-based design process that centres on the behaviours and needs of users. The clear benefits of UX offered in the retail and consumer sectors have been slow to percolate to other more complex sectors such as the life sciences. As the benefits of adoption of UX come to be realised, we see steady and strong growth in the R&D life sciences sector. By Jacek Ziemski, Simon

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22:17

Evolving Models for NASH Drug Discovery: Tools for...

The Drug Discovery World Podcast ·

2020/11/10

Non-alcoholic fatty liver disease (NAFLD) has quietly become one of the most common causes of chronic liver disease in the modern world. If this prevalence is allowed to continue the economic and clinical burden will reach a staggering level. Non-alcoholic fatty liver disease (NAFLD) consists of a complex combination of liver maladies, ranging from benign hepatic steatosis (fatty liver) to its more aggressive inflammatory manifestation, non-alcoholic steatohepatitis (NASH). In parallel to soaring

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19:14

Reducing the PAINS in High Throughput Screening:...

The Drug Discovery World Podcast ·

2020/10/27

This article will describe, with examples, how understanding the likely mechanisms of false positives in advance of screening informs the design of the hit triage, thus increasing the likelihood of discovering optimisable chemical matter and avoiding costly wasting of resource. We describe the use of a bespoke ‘Robustness Set’ of nuisance compounds and how it can be used in conjunction with adjusting the conditions of the assay. We also present an example where hit identification was initially

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20:04

The COVID-19 Race: how mouse models will help...

The Drug Discovery World Podcast ·

2020/10/13

The emergence of SARS-CoV-2 virus and the disease it causes, COVID-19, have fuelled significant shifts in preclinical research across the globe. Amid the worldwide health emergency created by high infection rates, rapid transmission spread and relatively high mortality rates, researchers are under pressure to understand the disease’s pathogenesis, develop and test investigational therapeutics and explore viable vaccine approaches. By Dr Megan MacBride If you'd like to view the original article then

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17:09

Cryo-EM accelerates drug discovery by delivering...

The Drug Discovery World Podcast ·

2020/09/22

Cryo-electron microscopy (cryo-EM), a powerful biophysical technique that can analyse molecular assemblies, is changing the paradigm in structure-based drug design. As targets become more challenging, solving structures of drug target molecules or biologics becomes increasingly difficult. Cryo-EM empowers drug discovery teams to take advantage of rational drug design for many more major drug target classes, opening a pathway to best-in-class drugs. Cryo-EM allows the structural analysis of protein

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30:52

The Reality of Virtual Pharmaceutical Companies

The Drug Discovery World Podcast ·

2020/09/08

In this episode, we discuss the oxymoronic proposition of a Virtual Pharmaceutical Company (VPC) and the typical adopted business model, as well as provide examples of such companies currently trying to undertake this adventurous task. The vagaries and complexities of bringing a therapeutic drug to market through the Drug Discovery and Development (DDD) process are well known and described. Any company that undertakes such a time-consuming, financially-burdensome, risk-laden task must have access to

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28:18

Race To COVID-19 Cure - The Core Model for solving...

The Drug Discovery World Podcast ·

2020/08/25

Mitigation of COVID-19 pandemic requires a combination of effective epidemiological policies and the discovery/development of powerful drugs against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes this disease. This two part article series examines the major initiatives being explored at the public policy level to contain the spread of COVID-19 as well as some of the most important innovative collaborative efforts at the research and development front to combat

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