Unexpected Elements

61:45

Making a Covid-19 vaccine for two billion people

Unexpected Elements ·

2020/07/26

There's been encouraging news about the Oxford Covid-19 vaccine this week from a trial involving about 1,000 people. But how great is the challenge in scaling up from making a few thousand doses of the vaccine to manufacturing two billion by the end of this year? Sandy Douglas of Oxford's Jenner Institute explains how they plan to mass-produce the vaccine safely given the speed and magnitude of the scale up. A new kind of treatment for Covid-19 may come from an unlikely source: llamas and

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53:30

How long do Covid-19 antibodies last?

Unexpected Elements ·

2020/07/18

Science in Action looks at some of the latest research on how response of our immune system to infection by the coronavirus. Researchers at Kings College London find that protective antibodies appear to fade away after about three months following infection whereas a team at the Karolinska Institute has discovered that although antibodies may decline, other important players called T cells in our defences do not. Dr’s Katie Doores and Marcus Buggert talk about the implications of these

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68:06

Rwanda’s game changing coronavirus test

Unexpected Elements ·

2020/07/11

African scientists have developed a reliable, quick and cheap testing method which could be used by worldwide as the basis for mass testing programmes.The method, which produces highly accurate results, is built around mathematical algorithms developed at the African Institute for Mathematical Sciences in Kigali. We speak to Neil Turok who founded the institute, Leon Mutesa Professor of human genetics on the government coronavirus task force, and Wilfred Ndifon, the mathematical biologist who

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63:42

Covid-19 and children

Unexpected Elements ·

2020/07/05

Studies in children who have been severely affected by Covid-19 in Italy, Britain and the US are showing the same thing – a range of symptoms linked to an overactive immune system. Elizabeth Whittaker from London’s Imperial College discusses the similarities in these cases and possible reasons for this syndrome with Shanna Kowalsky from Mount Sinai hospital in New York. How much should drugs for Covid-19 cost? Remdesivir, which has shown promise against the virus, has been priced at over $2000 for a

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67:23

Record high temperatures – in the Arctic

Unexpected Elements ·

2020/06/28

A record summer temperature in Siberia is an indication of major changes in the Arctic climate. Changing weather patterns there have a knock on effect for other parts of the planet says Climatologist Steve VavrusChile appeared to get Covid-19 under control, but in reality the virus was spreading uncontrollably through poor areas, As we hear from our correspondent in Santiago Jane Chambers, the lockdown has tightened but cases continue to rise.And could mass testing using new saliva tests help

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71:36

Covid -19 hope for severe cases

Unexpected Elements ·

2020/06/21

A multi arm trial testing a range of drugs has shown that readily available steroids can be lifesaving for people severely ill with Covid-19. Max Parmar, head of the UK Medical Research Council’s clinical trials unit says the trial design, where many potential drugs can be tested against the same controls, is key to producing results quickly. As it spreads around the world SARS-CoV-2 is mutating. But what does this mean? These mutations are part of a natural process and some researchers are finding

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64:01

Food security, locusts and Covid -19

Unexpected Elements ·

2020/06/14

Despite the Covid-19 pandemic efforts to counter massive swarms of locusts across East Africa have continued. In many places this has been very effective, killing up to 90% of locusts. However, the threat of repeated waves of locusts remains says Cyril Ferrand, who leads the UN Food and Agriculture Organisation's Resilience Team in East Africa.Conversely West Africa is unaffected by locusts and with a block on imports local producers have seen demand grow for their produce, an unusual positive

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65:15

The medical complexity of Covid -19

Unexpected Elements ·

2020/06/07

Autopsies show Covid 19 can affect the brain and other organs. Pathologist Mary Fowkes from the Icahn School of Medicine at Mount Sinai found the signs of stroke - unusually in young people, as well as a disruption of the immune system throughout the body.And studies of heart stem cells show these can be killed by the virus. Cell Biologist Stefanie Dimmeler from the University of Frankfurt says this finding could prove useful in providing treatment and preventative medicine.A massive research

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77:47

Brazil’s Covid chaos

Unexpected Elements ·

2020/05/31

The number of cases of Covid -19 infections in Brazil and deaths related to the pandemic may be much higher than official figures show. Testing of the living is not widespread and there are few resources for analysing the potential role of the virus as a cause of death. Virologist Fernando Spiliki gives us his bleak assessment.A remarkable study from South Africa shows just how easily the virus can spread around a hospital, with a single infected person infecting many. However the route of infection

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78:14

Loosening lockdown

Unexpected Elements ·

2020/05/17

How is Covid -19 spread? Who is most at risk and what are the circumstances under which it is most likely to be transmitted? These questions need answers for the implementation of effective and safe strategies to end lockdown. We look at what research is showing. And if you have to go back to work what’s the best way to protect yourself, how should we be using face coverings for example? There are lessons from research on fluid dynamics.Also key is reducing the rate of infection, the R number, Italy

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75:23

Covid -19 new hope from blood tests

Unexpected Elements ·

2020/05/10

Research from New York examining the blood of people who have recovered from Covid – 19 shows the majority have produced antibodies against the disease, The researchers hope to soon be able to establish whether this confers long term immunity as with more common viral infections. And Research in Berlin and London has identified biomarkers, minute signs of the disease which may help clinicians identify who is likely to develop severe symptoms and what kind of treatment they might need.Mutations have

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84:19

Ebola drug offers hope for Covid-19

Unexpected Elements ·

2020/05/03

Remdesivir a drug eventually rejected as a treatment for Ebola seems to have aided recovery in a trial with more than a thousand Covid -19 patients. Researchers are cautious but hopeful; a leading health official in the US has made comparisons with the impact of game changing drugs used to treat HIV. In contrast an organisation researching the mechanisms by which bat coronaviruses infect humans has had its funding cut following criticism from President Trump.A scheme to help manufacture ventilators

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77:08

Presidents and pandemics

Unexpected Elements ·

2020/04/26

President Trump has repeated unfounded claims that scientists created Covid-19 in a lab. Rigorous scrutiny of the genetics of the virus reveals no evidence for such a claim. And Brazil’s President Bolsonaro is at odds with his own health advisors – splitting public opinion and action over lockdown measures needed to control the virus. We also look at why Covid -19 seems to be associated with so many different symptoms, from diarrheal infections to complicating kidney disease, to heart attacks And

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49:40

Italy, getting Covid 19 under control

Unexpected Elements ·

2020/04/19

Italy is beginning its first tentative steps towards ending its lockdown. These are small steps, opening a few shops in areas where virus transmission has seen big falls. Part of the reason for this controlled strategy is that there are real concerns over a potential resurgence of the virus, Around the world there are now hundreds of trials on drug treatments for Covid 19. Results so far are mixed, with antivirals developed for Ebola and HIV showing positive signs, but antimalarial drugs, championed

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53:47

The impossibility of social distancing and even...

Unexpected Elements ·

2020/04/12

Massively over crowded Moria refugee camp on the Greek island of Lesbos has seen numbers grow from 5 to 20 thousand in a matter of months. Hundreds of people share taps and toilets, there is little chance to implement measures designed to stop the spread of covid 19. So far the camp has not been hit by the epidemic, but aid agencies fear for the most vulnerable in the camp. Covid 19 jumped from bats to humans, possibly via another wild animal. A study of zoonotic diseases has identified many other

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58:21

Covid 19 – The fightback in Africa begins

Unexpected Elements ·

2020/04/05

Nigeria has seen a small number of Covid -19 cases, largely spread amongst the most affluent, people who travel abroad, However there is concern about the potential of the virus to spread to overcrowded slum areas. In such conditions social distancing measures would be difficult to enforce. What are the alternatives? The US now has the majority of cases of the virus, New York has been heavily hit, medics have developed an app to help understand the spread of Covid 19 in the community. The

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67:03

The science of social distancing

Unexpected Elements ·

2020/03/29

The strong social distancing policies introduced by China seem to have been successful in stopping the spread of Covid 19. Without any effective drug treatments, reducing our number of contacts is the most effective way to prevent viral transmission.We also look at the similarities been policies in Russia and the US on how best to deal with the virus. In both cases there are contradictions and disagreements between medical professionals and politicians.And a warning from Polio, how vaccines may

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66:39

Covid -19, are you carrying the virus?

Unexpected Elements ·

2020/03/22

In Italy the entire population of a small town was tested for Covid 19. Of those infected, one in three people with no symptoms had the virus. And from China researchers found many people carried the virus – even before authorities there began tracking its spread. The findings suggest vulnerable people may contract the virus from those without symptoms.And we’ve news of a breakthrough - new tests looking at Covid 19 antibodies, These should help provide a picture of developing immunity to the

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67:54

Covid -19 how infectious is it really?

Unexpected Elements ·

2020/03/15

Covid- 19 cases seem to be multiplying daily and there is now a growing body of scientific evidence both on its spread and the effectiveness of measures to try and control it. We look at what’s working, what’s not and why. And we look to the potential for coronavirus drug treatments, why despite the hype there really isn’t anything round the corner.Australia’s recent fire season was intense; a new study looks back over 500 years of the weather pattern partly responsible, the Indian Ocean Dipole. The

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62:24

Australia’s fires - fuelled by climate change

Unexpected Elements ·

2020/03/08

Attributing Australia's bush fires, a major study says man-made climate change was a big driver – making the fires at least 30% worse than they would have been if natural processes were the only factors.We look at preparations for coronavirus in Africa. Although cases there are currently lower than in much of the rest of the world a major training initiative is taking place to spread awareness amongst medics across the continent.We ask why Horseshoe bats in particular carry coronaviruses, and find a

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