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PODCAST

OncoPharm

OncoPharm is a podcast dedicated to all things oncology pharmacy. Most episodes cover updates and recent publications concerning the use of medications in caring for patients with cancer. Periodically, episodes drop devoted to Landmark Clinical Trials in oncology and Fundamentals of Oncology Pharmacy.

science

All Episodes

00:20:29

Zanubrutinib

OncoPharm ·

2019/11/21

BTK-targeting therapy approved again! Zanubrutinib approved for Mantle Cell Lymphoma (2nd line) - how does it compare to ibrutinib and acalabrutinib?

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00:15:50

Immunotherapy Interactions

OncoPharm ·

2019/11/14

Examining the effects of antibiotics, corticosteroids (6:45), and cannabis (12:05) on immunotherapy effectiveness.

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00:17:02

Data Dive Into NK-1 Antagonists & Carboplatin

OncoPharm ·

2019/11/07

ASCO's updated 2017 antiemetic guidelines recommend NK-1 antagonists to prevent CINV with standard Q 3 week carboplatin (i.e. AUC 5-6), but how good are the data to support that? We dive into the supporting data.

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00:20:57

Carboplatin

OncoPharm ·

2019/10/31

The basic must-know information for carboplatin, for students, residents, or anyone looking for a refresher.

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00:18:10

ADAM VTE & Ibrutinib CV Toxicity

OncoPharm ·

2019/10/24

ADAM VTE (apixaban for cancer-associated VTE) results have been published - let's talk about it. Also, what are the implications of long term ibrutinib on CV health? A new Blood paper offers some possible answers.

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00:14:32

To Rechallenge, Or Not To Rechallenge

OncoPharm ·

2019/10/17

Weighing the risks & benefits of immunotherapy rechallenge in patients with a prior immune-related adverse event (irAE). Reference: https://www.ncbi.nlm.nih.gov/pubmed/31461381

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00:11:19

CASPIAN

OncoPharm ·

2019/10/10

Reviewing the recent Lancet publication of CASPIAN (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32222-6/fulltext) --> durvalumab + chemo in extensive stage small cell lung cancer.

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00:22:16

ESMO 2019

OncoPharm ·

2019/10/03

Recapping updates from ESMO 2019. Topics include FLAURA (osimertinib), 5-year OS analyses of immunotherapy in metastatic NSCLC & melanoma, EGFR/BRAF/MEK inhibition in BRAF-V600E colorectal cancer, PARP inhibitors in ovarian cancer, and a possible cabazitaxel comeback.

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00:14:19

Danorubicin 90 mg/m2 (AML induction)

OncoPharm ·

2019/09/24

The Landmarks in #Oncopharm series returns on the 10-year anniversary of this landmark paper (https://www.nejm.org/doi/10.1056/NEJMoa0904544) comparing daunorubicin 90 mg/m2 vs. 45 mg/m2 for AML induction.

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00:16:35

New FDA approved indications for lenvatinib, pembro,...

OncoPharm ·

2019/09/19

Discussion of FDA's approval of lenvatinib & pembrolizumab for endometrial cancer followed by a comparison of TITAN v. ENZAMET prompted by apalutamide's latest approval.

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00:15:39

Curious Case Of Ibrutinib On Netflix

OncoPharm ·

2019/09/12

Recapping the NY Times (https://www.nytimes.com/interactive/2018/10/26/magazine/netflix-diagnosis-series-joe.html) & Netflix collaboration "Diagnosis" about a possible Ibrutinib ADR. We also the discuss the value of case reports for the #OncoPharm community.

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00:13:06

OncoPharm M & M Extreme Toxicity & Pharmacogenetics

OncoPharm ·

2019/09/05

The 2nd installment of the OncoPharm Morbidity & Mortality series discussed a published case report (https://www.ncbi.nlm.nih.gov/pubmed/28782406). We discuss the approach to take when a patient experiences unexpectedly extreme toxicity and the role pharmacogenetics may play. Suggested resource: https://cpicpgx.org

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00:17:29

Irinotecan

OncoPharm ·

2019/08/29

The Foundations of #OncoPharm series returns with all the must-know information for irinotecan.

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00:19:03

Entrectinib & Fedratinib

OncoPharm ·

2019/08/22

Running through the drug information highlights of the latest approved #oncopharm agents: entrectinib and fedratinib.

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00:19:15

E1912: Ibrutinib/rituximab vs. FCR in CLL

OncoPharm ·

2019/08/15

This week we look at the NEJM publication earlier this month (https://www.nejm.org/doi/full/10.1056/NEJMoa1817073) of E1912. Points of discussion include IGHV mutational status, PFS vs. OS as endpoints in CLL, the benefit of rituximab in addition to ibrutinib, and ibrutinib toxicity in younger vs. older CLL patients. (Also, apologies to my APPE student for dropping this Pod *after* your journal club on this paper.)

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00:26:52

ASCO VTE Guidelines (& more!)

OncoPharm ·

2019/08/08

Updates on ASCO's updated VTE guidelines with a focus on prophylaxis for ambulatory cancer patients (1:15) and VTE treatment (12:50). Pembrolizumab's latest FDA-approval is discussed (16:00), as is pexidartinib's FDA-approval (18:00), and finally a comparison of BCOP pass rates by training status (22:34).

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00:16:44

Darolutamide

OncoPharm ·

2019/07/31

Darolutamide has been FDA-approved. We discuss its differences and similarities to other 2nd-generation anti-androgens (enzalutamide & apalutamide) - especially potential drug interactions!

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00:16:19

AC - - > T (q week)

OncoPharm ·

2019/07/25

Our Landmarks in #OncoPharm series returns to the breast cancer patient population to review the landmark 2008 NEJM article from Sparano et al (https://www.nejm.org/doi/full/10.1056/NEJMoa0707056) investigating the optimal taxane regimen to follow adjuvant AC.

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00:15:04

Selinexor

OncoPharm ·

2019/07/18

A brief discussion on FDA's approval decision on selinexor and its possible role in therapy. Then, a more in-depth details on its MOA, dosing, and toxicity profile.

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00:30:34

Pain Management In Cancer

OncoPharm ·

2019/07/11

An overview of pain management principles in cancer patients. Topics covered include the role of NSAIDs, bisphosphonates, and opioids in treating or preventing pain. Also discussed: bowel regimens & opioid conversions.

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