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PODCAST

Psychopharmacology and Psychiatry Updates

Psychopharmacology Institute

Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.

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All Episodes

10:51

Dementia Risk and Vitamin D

Psychopharmacology and Psychiatry Updates ·

2025/05/31

In this episode, we explore compelling evidence from the UK Biobank showing how vitamin D deficiency may increase dementia risk by up to 25%. Could this affordable supplement be an essential piece of your brain health strategy? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: Quick Take Vol. 68 Can Vitamin D Deficiency Increase the Risk of Alzheimer's Disease?

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13:41

Beyond Benzos: Strategies for Successful Deprescribing

Psychopharmacology and Psychiatry Updates ·

2025/05/26

In this episode, we explore the complex process of benzodiazepine deprescribing, examining when and how to help patients reduce or discontinue these medications. How can clinicians balance the benefits of deprescription against the challenges of withdrawal? Faculty: Alexis Ritvo, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CMEs: Strategies for Successful Benzodiazepine Deprescribing Benzodiazepine Deprescription: Indications, Benefits, and Risks

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12:06

Motherhood and Medication: LAIs for Women with...

Psychopharmacology and Psychiatry Updates ·

2025/05/21

In this episode, we explore the unique considerations for using long-acting injectable antipsychotics in women with schizophrenia. How might hormonal fluctuations throughout a woman's life impact treatment decisions for schizophrenia? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: Quick Take Vol. 68 Long-Acting Antipsychotics: An Option for Women with Schizophrenia?

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09:30

Benzodiazepines in High-Risk Populations

Psychopharmacology and Psychiatry Updates ·

2025/05/16

In this episode, we explore the challenges and current guidelines for benzodiazepine use in pregnancy, breastfeeding, and adolescence. When is it appropriate to continue benzodiazepines during pregnancy, and what alternatives should clinicians consider? Faculty: Alexis Ritvo, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Understanding Benzodiazepine Prescribing: A Clinician's Guide Consequences of Benzodiazepine Use in Pregnancy, Breastfeeding, and

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12:27

Benzodiazepines: Understanding Physical Dependence...

Psychopharmacology and Psychiatry Updates ·

2025/05/11

In this episode, we explore benzodiazepine use disorder, distinguishing between physical dependence and addiction while examining practical strategies for safe prescribing. Did you know only 1.5% of benzodiazepine users actually develop a use disorder? Faculty: Alexis Ritvo, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Understanding Benzodiazepine Prescribing: A Clinician's Guide Benzodiazepine Use Disorder

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12:46

Beyond Metformin: Probiotics and Antipsychotic Weight...

Psychopharmacology and Psychiatry Updates ·

2025/05/06

In this episode, we explore the potential role of the probiotic Akkermansia muciniphila in managing olanzapine-induced weight gain. Could this tiny gut bacterium be the key to maintaining metabolic health while on antipsychotics? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: Quick Take Vol. 67 Olanzapine-Induced Weight Gain: Can Akkermansia Muciniphila Help?

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09:48

What Every Clinician Should Know About the Risks of...

Psychopharmacology and Psychiatry Updates ·

2025/05/01

In this episode, we explore the dangerous risks of benzodiazepine use, focusing on the potentially lethal combination with opioids, cognitive impairment, increased accident risk, and fall hazards. Did you know that benzodiazepines combined with opioids increase overdose risk fivefold in the first 90 days? Faculty: Alexis Ritvo, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Understanding Benzodiazepine Prescribing: A Clinician's Guide Understanding the Major Risks

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11:31

Making an Exit Plan: Navigating Antidepressant...

Psychopharmacology and Psychiatry Updates ·

2025/04/26

In this episode, we explore the latest research on antidepressant discontinuation symptoms, revealing that about 14% of patients experience these effects when stopping medication. Which antidepressants are most likely to cause these "brain zaps" and other withdrawal symptoms? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CME: Quick Take Vol. 67 Which Antidepressants Have the Highest Risk of Discontinuation Symptoms?

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11:54

Clinical Pearls for Selecting the Right Benzodiazepine

Psychopharmacology and Psychiatry Updates ·

2025/04/21

In this episode, we discuss the appropriate use of benzodiazepines, focusing on evidence-based indications and optimal medication selection. Did you know that alprazolam has unique properties that make it more addictive than other benzodiazepines? Faculty: Alexis Ritvo, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: Understanding Benzodiazepine Prescribing: A Clinician's Guide Appropriate Benzodiazepine Use: Indications and Optimal Selection

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16:27

TMS for Depression: From Clinical Trials to Results

Psychopharmacology and Psychiatry Updates ·

2025/04/16

In this episode, we explore the evidence behind Transcranial Magnetic Stimulation (TMS) for depression, from early clinical trials to real-world effectiveness. What makes some patients respond better to TMS than others? We discuss response rates, treatment protocols, and the exciting development of faster treatment options. Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices Exploring the Evidence

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13:35

A Guide to Selecting TMS Candidates

Psychopharmacology and Psychiatry Updates ·

2025/04/11

In this episode, we explore the crucial aspects of patient selection for Transcranial Magnetic Stimulation (TMS) in treating depression. We discuss insurance criteria, contraindications, and practical considerations. Did you know that while TMS was FDA-approved in 2008, it wasn't widely accessible until Medicare began covering it in 2014? Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices

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13:07

Rethinking Clozapine Monitoring: 22 Years of Data

Psychopharmacology and Psychiatry Updates ·

2025/04/06

In this episode, we explore a landmark Finnish study examining the long-term risk of agranulocytosis in patients taking clozapine. The research followed 62,000 patients over 22 years, providing crucial data about this rare but serious side effect. Could these findings change how we approach clozapine prescribing and monitoring requirements? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 66 Does Clozapine's

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08:32

Understanding TMS in OCD: Evidence and Practice

Psychopharmacology and Psychiatry Updates ·

2025/04/01

In this episode, we explore Transcranial Magnetic Stimulation (TMS) as a treatment option for Obsessive-Compulsive Disorder (OCD). We discuss the FDA-approved devices, unique protocols, and why patients need their anxiety triggered before each session. Did you know TMS for OCD targets a completely different brain region than TMS for depression? Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices

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10:27

Breaking Down the TRAILBLAZER-ALZ 2 Trial

Psychopharmacology and Psychiatry Updates ·

2025/03/27

In this episode, we explore donanemab, a groundbreaking monoclonal antibody treatment for Alzheimer's disease. We discuss its efficacy in reducing beta-amyloid plaques, unique treatment duration protocol, and safety considerations. Could this time-limited treatment approach revolutionize how we manage Alzheimer's progression? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 66 Can Donanemab Slow Alzheimer's Progression?

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10:58

Long-term Benzo Use: What The Data Really Show

Psychopharmacology and Psychiatry Updates ·

2025/03/22

In this episode, we explore a groundbreaking Danish registry study that challenges common beliefs about long-term benzodiazepine use and dose escalation patterns. Are our concerns about inevitable tolerance and dependence justified? The study's findings might surprise you and reshape prescribing practices. Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 65 Do Benzodiazepine Users Escalate Doses Over Time?

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08:05

Navigating TMS Side Effects: A Practical Guide

Psychopharmacology and Psychiatry Updates ·

2025/03/17

In this episode, we explore the side effects and safety considerations of Transcranial Magnetic Stimulation (TMS) therapy in psychiatry. Did you know that despite common concerns, fewer than 2% of patients discontinue TMS due to discomfort? We'll discuss everything from common side effects to practical management strategies. Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices Assessing the Potential

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11:06

SSRIs and Anticoagulants: Navigating Bleeding Risk

Psychopharmacology and Psychiatry Updates ·

2025/03/12

In this episode, we explore the crucial interaction between SSRIs and oral anticoagulants, examining a groundbreaking 23-year study of over 330,000 patients. Does combining these medications significantly increase bleeding risk, and if so, how can we safely manage patients who need both treatments? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 65 Can SSRIs Be Safely Prescribed With Oral Anticoagulants?

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07:38

Lamotrigine and the Heart: What You Need to Know

Psychopharmacology and Psychiatry Updates ·

2025/03/07

In this episode, we explore the safe use and monitoring of lamotrigine, focusing on cardiac risks and when EKG monitoring is necessary. Did you know that reducing lamotrigine dose doesn't actually mitigate cardiac risks but could increase the risk of psychiatric destabilization? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Lamotrigine: From Current Indications to Cardiac Side Effects Strategies for Safe Usage and Proper Monitoring of

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11:27

After the Last Dose: Understanding Antipsychotic...

Psychopharmacology and Psychiatry Updates ·

2025/03/02

In this episode, we explore the often-overlooked phenomenon of antipsychotic withdrawal, examining new findings from the world's largest drug safety database. Could some cases of apparent psychotic relapse actually be withdrawal symptoms in disguise? We discuss common withdrawal effects, risk factors, and evidence-based strategies for safe medication discontinuation. Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 64

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07:38

Understanding Lamotrigine's Cardiac Effects

Psychopharmacology and Psychiatry Updates ·

2025/02/25

In this episode, we explore lamotrigine's cardiac side effects, focusing on QTc prolongation and QRS widening. How concerned should psychiatrists be about the FDA warning regarding lamotrigine's cardiac effects? We examine the evidence behind these concerns and discuss practical implications for clinical practice. Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Lamotrigine: From Current Indications to Cardiac Side Effects Lamotrigine Effect

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