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PODCAST

Psychopharmacology and Psychiatry Updates

Psychopharmacology Institute

Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.

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All Episodes

16:27

TMS for Depression: From Clinical Trials to Results

Psychopharmacology and Psychiatry Updates ·

2025/04/16

In this episode, we explore the evidence behind Transcranial Magnetic Stimulation (TMS) for depression, from early clinical trials to real-world effectiveness. What makes some patients respond better to TMS than others? We discuss response rates, treatment protocols, and the exciting development of faster treatment options. Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices Exploring the Evidence

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13:35

A Guide to Selecting TMS Candidates

Psychopharmacology and Psychiatry Updates ·

2025/04/11

In this episode, we explore the crucial aspects of patient selection for Transcranial Magnetic Stimulation (TMS) in treating depression. We discuss insurance criteria, contraindications, and practical considerations. Did you know that while TMS was FDA-approved in 2008, it wasn't widely accessible until Medicare began covering it in 2014? Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices

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13:07

Rethinking Clozapine Monitoring: 22 Years of Data

Psychopharmacology and Psychiatry Updates ·

2025/04/06

In this episode, we explore a landmark Finnish study examining the long-term risk of agranulocytosis in patients taking clozapine. The research followed 62,000 patients over 22 years, providing crucial data about this rare but serious side effect. Could these findings change how we approach clozapine prescribing and monitoring requirements? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 66 Does Clozapine's

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08:32

Understanding TMS in OCD: Evidence and Practice

Psychopharmacology and Psychiatry Updates ·

2025/04/01

In this episode, we explore Transcranial Magnetic Stimulation (TMS) as a treatment option for Obsessive-Compulsive Disorder (OCD). We discuss the FDA-approved devices, unique protocols, and why patients need their anxiety triggered before each session. Did you know TMS for OCD targets a completely different brain region than TMS for depression? Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices

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10:27

Breaking Down the TRAILBLAZER-ALZ 2 Trial

Psychopharmacology and Psychiatry Updates ·

2025/03/27

In this episode, we explore donanemab, a groundbreaking monoclonal antibody treatment for Alzheimer's disease. We discuss its efficacy in reducing beta-amyloid plaques, unique treatment duration protocol, and safety considerations. Could this time-limited treatment approach revolutionize how we manage Alzheimer's progression? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 66 Can Donanemab Slow Alzheimer's Progression?

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10:58

Long-term Benzo Use: What The Data Really Show

Psychopharmacology and Psychiatry Updates ·

2025/03/22

In this episode, we explore a groundbreaking Danish registry study that challenges common beliefs about long-term benzodiazepine use and dose escalation patterns. Are our concerns about inevitable tolerance and dependence justified? The study's findings might surprise you and reshape prescribing practices. Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 65 Do Benzodiazepine Users Escalate Doses Over Time?

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08:05

Navigating TMS Side Effects: A Practical Guide

Psychopharmacology and Psychiatry Updates ·

2025/03/17

In this episode, we explore the side effects and safety considerations of Transcranial Magnetic Stimulation (TMS) therapy in psychiatry. Did you know that despite common concerns, fewer than 2% of patients discontinue TMS due to discomfort? We'll discuss everything from common side effects to practical management strategies. Faculty: Simon Kung, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1 CME: TMS in Psychiatry: Innovations and Best Practices Assessing the Potential

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11:06

SSRIs and Anticoagulants: Navigating Bleeding Risk

Psychopharmacology and Psychiatry Updates ·

2025/03/12

In this episode, we explore the crucial interaction between SSRIs and oral anticoagulants, examining a groundbreaking 23-year study of over 330,000 patients. Does combining these medications significantly increase bleeding risk, and if so, how can we safely manage patients who need both treatments? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 65 Can SSRIs Be Safely Prescribed With Oral Anticoagulants?

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07:38

Lamotrigine and the Heart: What You Need to Know

Psychopharmacology and Psychiatry Updates ·

2025/03/07

In this episode, we explore the safe use and monitoring of lamotrigine, focusing on cardiac risks and when EKG monitoring is necessary. Did you know that reducing lamotrigine dose doesn't actually mitigate cardiac risks but could increase the risk of psychiatric destabilization? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Lamotrigine: From Current Indications to Cardiac Side Effects Strategies for Safe Usage and Proper Monitoring of

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11:27

After the Last Dose: Understanding Antipsychotic...

Psychopharmacology and Psychiatry Updates ·

2025/03/02

In this episode, we explore the often-overlooked phenomenon of antipsychotic withdrawal, examining new findings from the world's largest drug safety database. Could some cases of apparent psychotic relapse actually be withdrawal symptoms in disguise? We discuss common withdrawal effects, risk factors, and evidence-based strategies for safe medication discontinuation. Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 64

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07:38

Understanding Lamotrigine's Cardiac Effects

Psychopharmacology and Psychiatry Updates ·

2025/02/25

In this episode, we explore lamotrigine's cardiac side effects, focusing on QTc prolongation and QRS widening. How concerned should psychiatrists be about the FDA warning regarding lamotrigine's cardiac effects? We examine the evidence behind these concerns and discuss practical implications for clinical practice. Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Lamotrigine: From Current Indications to Cardiac Side Effects Lamotrigine Effect

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12:09

Rethinking Falls: Are Sleep Medications Really to Blame?

Psychopharmacology and Psychiatry Updates ·

2025/02/20

In this episode, we examine a groundbreaking Danish study that challenges the conventional belief that sedative medications increase fall risk in older adults. Could untreated insomnia, rather than the medications used to treat it, be the real culprit behind falls in elderly patients? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CME: Quick Take Vol. 64 Insomnia in the Elderly: Do Sedatives Increase or Decrease Fall Risk?

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10:42

Navigating Lamotrigine's Side Effects

Psychopharmacology and Psychiatry Updates ·

2025/02/15

In this episode, we explore lamotrigine's side effects and special considerations, particularly focusing on identifying dangerous skin reactions, pregnancy considerations, and overdose risks. Did you know that Asian populations may require special genetic screening before starting lamotrigine due to increased skin reaction risks? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Lamotrigine: From Current Indications to Cardiac Side Effects

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09:23

Iloperidone in Bipolar Disorder: A New Treatment Option?

Psychopharmacology and Psychiatry Updates ·

2025/02/10

In this episode, we explore the efficacy and safety of iloperidone in treating bipolar disorder, examining new phase 3 trial data that reveals both promising results for mania symptoms and important considerations about side effects. Can this antipsychotic's favorable EPS profile outweigh its metabolic risks? Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 63 Iloperidone: A Potential Treatment Option for Bipolar

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08:44

Lamotrigine: Pearls for Prescribing

Psychopharmacology and Psychiatry Updates ·

2025/02/05

In this episode, we explore the vital aspects of prescribing lamotrigine, from its mechanisms to titration schedules. Did you know that birth control pills can cut lamotrigine levels in half within just one week? Understanding these interactions is crucial for safe and effective treatment. Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Lamotrigine: From Current Indications to Cardiac Side Effects Understanding Lamotrigine Mechanisms and

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10:19

Beyond Benzos: New Frontiers in Agitation Management

Psychopharmacology and Psychiatry Updates ·

2025/01/31

In this episode, we explore the pharmacological management of agitation in emergency settings, focusing on benzodiazepines and the novel medication dexmedetomidine. Did you know there's now a sublingual option that works through an entirely different mechanism than traditional anti-agitation medications? Faculty: Scott Zeller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: The Psychopharmacology of Agitation: Managing Behavioral Emergencies The Role of

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11:40

KarXT: A New Dawn in Antipsychotic Treatment

Psychopharmacology and Psychiatry Updates ·

2025/01/26

In this episode, we explore KarXT, a groundbreaking experimental antipsychotic that works through the cholinergic system rather than dopamine pathways. Could this novel approach revolutionize schizophrenia treatment by offering similar efficacy to current antipsychotics but without the motor side effects? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.75 CMEs: Quick Take Vol. 63 Xanomeline-Trospium (KarXT) Shows Efficacy in Phase 3 Trial

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10:50

Rethinking Agitation Management: From Force to...

Psychopharmacology and Psychiatry Updates ·

2025/01/21

In this episode, we explore evidence-based pharmacologic strategies for managing acute agitation in emergency settings, challenging the stigmatizing concept of “chemical restraints” and providing practical approaches to achieve optimal patient outcomes. Did you know that many agitated patients can actively participate in medication decisions, even during a crisis? Faculty: Scott Zeller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: The Psychopharmacology of

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10:56

COVID Brain Fog: Repurposing Famotidine

Psychopharmacology and Psychiatry Updates ·

2025/01/16

In this episode, we explore how famotidine, a common heartburn medication, might help treat post-COVID brain fog. New research suggests this H2 blocker could improve cognitive function in recovering patients. But how does a stomach acid reducer potentially clear mental haziness? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 62 Famotidine for COVID-19 Brain Fog: A Promising Treatment Option

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11:45

Beyond Restraints: De-Escalation in Behavioral...

Psychopharmacology and Psychiatry Updates ·

2025/01/11

In this episode, we explore nonpharmacologic strategies for managing agitated patients, focusing on verbal de-escalation techniques. Did you know that using physical restraints adds an average of four hours to an emergency department stay? Dr. Scott Zeller shares evidence-based approaches to transform crisis intervention in emergency settings. Faculty: Scott Zeller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: The Psychopharmacology of Agitation: Managing

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411 results

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