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PODCAST

The Beagle Has Landed Podcast

Hosted by renowned educator and genetic counselor, Laura Hercher, The Beagle Has Landed is the first independent podcast for the rapidly growing and dynamic community of genetic counselors. The show features interviews with leaders in the field of clinical genetics, exploring our complicated past and rapidly changing present. We look at the new roles genetic counselors are playing in industry as well as clinical settings, bringing in the voices of other stakeholders, including basic scientists and

science & medicine natural sciences

All Episodes

Louise Bier

The Beagle Has Landed Podcast ·

2019/11/13

As we get underway with All of Us, the huge tax-payer funded project to assemble a database or genomic and medical information on 1 million Americans, there are people working hard to make sure it fulfills two founding principles. First, to treat participants like partners (and this means giving them access to the results). And second, to make sure this effort leaves no one out.

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Rayna Rapp

The Beagle Has Landed Podcast ·

2019/11/01

Rayna Rapp is Professor of anthropology and an affiliate at the center for disability studies at NYU. Laura welcomes Rayna Rapp, feminist, medical anthropologist and all-around sage, who has worked for decades in the study of the social impact of prenatal genetic testing. Her 1999 book, "Testing Women; Testing the Fetus; the Social Impact of Amniocentesis in America," is a classic that has influenced generations of genetic counselors.

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Jordan Smoller

The Beagle Has Landed Podcast ·

2019/10/17

Families and individuals dealing with mental illness have lots of questions about genetic testing. Does it work? Can it help doctors choose the right course of treatment? Can it predict who is likely to get sick? Are the tests they are selling on line today the real deal?

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Kif Augustine-Adams

The Beagle Has Landed Podcast ·

2019/06/20

Kif Augustine-Adams is the Ivan Meitus Chair and a professor the Brigham Young University J. Reuben Clark School of Law whose work has focused on protecting immigrant women and children. A feminist and advocate with an interest in history, Kif was well aware of the threats that women face in the world, but she had no notion of the story of sexual violence and abuse that was hidden in her own DNA. Our 21st Century DNA databases did not create the harm, but merely revealed it and, Kif argues, that’s

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Kevin Mitchell

The Beagle Has Landed Podcast ·

2019/06/04

Kevin Mitchell (AKA “Wiring the Brain”) joins us on The Beagle to discuss the use of so-called polygenic risk scores to select for “the smartest embryos,” as a recent Guardian article put it. Can we, and should we, do any such thing? Kevin Mitchell is Associate Professor in the Smurfit Institute of Genetics in Trinity College Dublin and a member of the Trinity College Institute of Neuroscience, and a philosopher-scientist who writes frequently on the mechanisms and deeper meaning of brain

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Kiran Musunuru, Verve Therapeutics

The Beagle Has Landed Podcast ·

2019/05/21

Kiran Musunuru, Associate Professor at the University of Pennsylvania Perelman School of Medicine, is back on The Beagle to talk about Verve Therapeutics, a company that announced its arrival earlier this month, with the modest goal of protecting the world from heart disease (honestly, “protect the world form heart disease" IS the Verve tagline).

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Eric Topol

The Beagle Has Landed Podcast ·

2019/05/07

As the Gary and Mary West Professor of Innovative Medicine and Founder/Director of the Scripps Translational Institute, Eric Topol is in the visionary business, trying to imagine what medicine will look like in the future. His current book, Deep Medicine, explores how artificial intelligence will affect all aspects of healthcare – from the obvious stuff (reading x-rays) to the not-so-obvious (creating digital twins for research studies).

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Elissa Levin

The Beagle Has Landed Podcast ·

2019/04/11

Elissa Levin was one of the first genetic counselors to work in the direct-to-consumer sector, starting at DNA Direct (remember that?); she’s been at Illumina-spinoff Helix for about 3 years. Helix runs a DTC marketplace, offering an the all-purpose DNA test (exome plus microarray) that can be queried by any of their testing partners. Now Helix has partnered with PerkinElmer to produce a new entry for its own marketplace -- the PerkinElmer GenePrism test.

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Amy Sturm

The Beagle Has Landed Podcast ·

2019/03/26

Amy Sturm is the head of cardiovascular genomic counseling at the Genomic Medicine Institute at Geisinger, that surprisingly cutting edge in the middle of nowhere (I’ve been there; trust me). Amy, a cardiogen pioneer for almost 20 year (cue Amy, gasping) is also the current President of the National Society of Genetic Counselors.

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Wendy Chung

The Beagle Has Landed Podcast ·

2019/02/28

Wendy Chung (MD, PhD) is the Kennedy Family Professor of Pediatrics in Medicine at Columbia University… and the Director of the Pediatric Neuromuscular Network Molecular Core, the New York Obesity Center Molecular Genetics Core, Columbia’s Clinical Cancer Program and DISCOVER program and…really it never ends. The busiest woman in genetics takes a few minutes out to talk to us about her early dreams (agricultural science; I kid you not) and the focus of some of her earliest human work: the

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Ellen Matloff

The Beagle Has Landed Podcast ·

2019/02/20

Ellen Matloff has one of the most unique stories in genetic counseling today. She worked at Yale to found the cancer counseling program in the early days of that discipline and was an early and highly visible voice in the battle against gene patenting. Eventually, her experience with the expanding presence of cancer susceptibility testing led her to found a business that attempts to provide a low-cost, scalable option to fill in the informational gaps for individuals who’ve had genetic

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Penny Wolfson and Ansel Lurio

The Beagle Has Landed Podcast ·

2019/02/06

Penny Wolfson’s book, Moonrise, grew out of her experiences after the diagnosis of her oldest son Ansel Lurio with Duchenne Muscular Dystrophy. Today Ansel is 34 and his biography far exceeds the limited expectations of the neurologists who counseled his parents when he was a toddler. Penny credits incremental improvements in care for the successes they’ve had to date. Her message to clinicians? Never assume you know for sure what the future will bring.

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Kiran Musunuru

The Beagle Has Landed Podcast ·

2018/12/07

“Genome editing had to happen sometime,” says our guest Kiran Musunuru, MD, PhD, MPH, internationally recognized Crispr expert and Laura's colleague on the American Society of Human Genetics’ task force on human germline genome editing. Kiran was one of the first to see He Jiankui’s paper on the birth of twin girls after the in vitro editing of their CCR5 gene, courtesy of the Associated Press. We discuss what comes next, as the dust settles on one of the most important science news stories of

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MaryAnn Campion

The Beagle Has Landed Podcast ·

2018/11/27

Everyone says we need more genetic counselors, but few people have put as much time and effort into creating them as MaryAnn Campion, current co-director of the Master’s Program in Human Genetics and Genetic Counseling at Stanford University. MaryAnn has a doctorate of Educational Leadership and Policy from Boston University, where she was also the founding director of the BU genetic counseling program. So it comes as a bit of a surprise that MaryAnn does not think we need to be so aggressive

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Rachel Adams

The Beagle Has Landed Podcast ·

2018/11/06

Rachel Adam’s life took an unexpected turn 11 years ago, when her son was diagnosed with Down syndrome shortly after birth. Her memoir, Raising Henry, is a deeply thoughtful and eloquent look at her own experience as a mother and her introduction into the Down syndrome community. She shares some of that eloquence with us, and talks about the challenge of being both a staunch believer in the right to choose, and an advocate for not only her son, but the whole concept of Down syndrome as an example

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Sek Kathiresan

The Beagle Has Landed Podcast ·

2018/10/29

Polygenic risk scores have burst onto the scene in 2018, not because they are new (they are not) but because after years of discouraging and anemic results, it seemed that perhaps this sort of amorphous “risk in your genes” -- the risk that remains after Mendelian variants are ruled out – was not something we would ever be able to quantify. And now, some new work is challenging that assumption. Can we make predictions based on tiny effect sizes in thousands of genes?

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Brianne Kirkpatrick Williams

The Beagle Has Landed Podcast ·

2018/10/23

If you survey genetic counselors about direct-to-consumer genetic testing (and we did!) you will find that most of them think that DTC customers should receive genetic counseling. At the same time, most of them say that they wouldn’t feel comfortable doing the counseling… In 2016, Brianne Kirkpatrick Williams set up Watershed DNA for just this purpose. In this interview, Brianne discusses the challenges and satisfactions of entrepreneurship and being a pioneer in the DTC genetic testing era.

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Brianne Kirkpatrick

The Beagle Has Landed Podcast ·

2018/10/23

If you survey genetic counselors about direct-to-consumer genetic testing (and we did!) you will find that most of them think that DTC customers should receive genetic counseling. At the same time, most of them say that they wouldn’t feel comfortable doing the counseling… In 2016, Brianne Kirkpatrick set up Watershed DNA for just this purpose. In this interview, Brianne discusses the challenges and satisfactions of entrepreneurship and being a pioneer in the DTC genetic testing era.

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Erica Ramos

The Beagle Has Landed Podcast ·

2018/10/09

Ever since she was a small child, Erica Ramos dreamed of being president of NSGC … Okay no. Erica talks about her path to the presidency, her least favorite thing about the job, and why she has trouble staying on message (ps she seems pretty on message to me). Plus, breaking news on the Beagle! Erica describes NSGC’s new diversity initiative, and what diversity means in the context of an organization of genetic professionals… spoiler alert: it’s about being inclusive of thought, experience and

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Matt Fender

The Beagle Has Landed Podcast ·

2018/09/25

In December 2017, Matt Fender ran his 23andMe raw data through Promethease, a third party DNA search engine that provides an inexpensive personalized list of annotated SNP’s. At the top of Matt’s report was a box banded in red that said “pathogenic” and “PSEN1” and “early onset Alzheimer’s disease.” At 32, Matt believed that dementia was only a few years off – on bad days, he thought perhaps it has already begun. He agonized over how to tell his family. And he discovered that when it came to DTC

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