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PODCAST

Depresh Mode with John Moe

John Moe, Maximum Fun

Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people

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All Episodes

00:51:13

Jonathan Edward Durham Was In Horrible Mental Shape...

Depresh Mode with John Moe ·

2026/03/02

Although he has a huge following on social media now, Jonathan Edward Durham’s life as a writer used to be a lot more low tech. It involved locking himself in a room in Los Angeles, pounding away on screenplays that almost no one ever read, sucking back smokes and liquor, barely sleeping, and finding himself to actually be pretty miserable. He did manage to write and self-publish a novel, Winterset Hollow, that found an audience, which led to getting online to promote it. He started to write more

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01:00:39

Huge Scientific Breakthroughs Are Changing How You’ll...

Depresh Mode with John Moe ·

2026/02/23

You might remember Alexandra Paul as one of the stars of Baywatch or the Tom Hanks-Dan Aykroyd Dragnet film. You may not have realized that as a child and on to her long trip through the worlds of modeling and Hollywood, she was bingeing and purging and dealing with severe eating disorders. She tells us about her relationship with sugar and what food meant emotionally. Then we’re joined by Dr. Cynthia Bulik, one of the top experts on eating disorders in the world today, to talk about remarkable

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00:51:27

Are Dating Apps a Mental Health Grenade? And, How Are...

Depresh Mode with John Moe ·

2026/02/16

Dating apps and websites are booming right now as people look for ways to leverage to find love or even just companionship. Liesel Sharabi of Arizona State University compiled a meta-analysis of a huge number of studies about the connection between online dating and mental health and the results? Kind of bad news. People who use the apps compulsively, swiping all day long, are much more likely to be depressed and anxious. But were they depressed because they used the apps or did the use the apps

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00:58:03

Niko Stratis on Dad Rock, Glasswork, Depression,...

Depresh Mode with John Moe ·

2026/02/09

Niko Stratis knew a couple of things growing up in the Yukon in Canada: that she was, in truth, a woman, despite being regarded by the world as male, and that being trans or different in any way was absolutely not okay. It wasn’t just a matter of identity, it was a matter of safety too, as she worked with guys who vowed that if their child was gay or trans, they would kill that child. Niko discovered some other things, too: the trade of industrial glassworking, the numbing effects of the alcohol she

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00:23:08

SPECIAL EPISODE: Mental Health and ICE in Minnesota

Depresh Mode with John Moe ·

2026/02/06

The ICE surge in Minnesota has meant a huge number of arrests, protests, confrontations, deportations, children and adults sent to detention facilities, and deaths. It’s also meant massive anxiety, fear, and trauma around the state. Marcus Schmit of NAMI Minnesota says this is being felt acutely among people already struggling with severe mental illnesses such as bipolar disorder, schizophrenia, and severe anxiety and depression. His organization has received overwhelming demand for help that they

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00:54:53

Amanda Knox on Facing Her Prosecutor, Her Past, Her...

Depresh Mode with John Moe ·

2026/02/02

In 2007, Amanda Knox, an American studying abroad in Italy, was arrested, tried, and convicted of the murder of her roommate, Meredith Kercher. After years in an Italian jail, she was ultimately freed, reconvicted, and finally exonerated in 2015. Since then, she has married, become a mother, and she has returned to Italy, even meeting with the prosector who concocted outrageous stories that led to her imprisonment. Their meeting is featured in Mouth of the Wolf: Amanda Knox Returns to Italy, a new

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01:03:23

Intentionally Blunt and Very Useful Talk About...

Depresh Mode with John Moe ·

2026/01/26

Suicide is a problem. It’s perpetually a top cause of death around the world but society shames it, stigmatizes it, and is reluctant to discuss it even when talking about it would save lives. Well guess what, we’re talking about it. We’re offering insight, sympathy, and practical ideas to help yourself and others.Clancy Martin first thought about suicide when he was two years old and he has attempted suicide many times over the years. “I’m extremely bad at it,” he says. Clancy is a philosophy

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00:52:24

Stephanie Foo on Complex PTSD, Finding Recovery, and...

Depresh Mode with John Moe ·

2026/01/19

It was several years into her talk therapy sessions that Stephanie Foo was offered a diagnosis: complex post-traumatic stress disorder, or C-PTSD. Regular PTSD stems from a single traumatic event like a car crash or a mugging. C-PTSD comes from a long series of traumas from which there seems like no escape. Like child abuse. The problems Stephanie was having with her relationships and rage and all sorts of other issues stemmed, said the therapist, from the severe abuse she encountered during her

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00:58:04

A.J. Daulerio on Bipolar, Substances, Depression,...

Depresh Mode with John Moe ·

2026/01/12

A.J. Daulerio exists as a caricature to a lot of people because he was the guy who published a clip from a Hulk Hogan sex tape on Gawker, got sued by Hogan, and he and Gawker lost to the tune of a $140 million payout. The enmity and shame of that was a lot to carry around, as was a lifelong battle with depression and bipolar disorder type II, as was a pretty profound problem with drug and alcohol abuse. But A.J. sobered up, got treatment, got therapy, and began to devote his energy to stories of

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00:41:58

Two Truths To Make 2026 a Better Mental Health Year

Depresh Mode with John Moe ·

2026/01/05

We live in complicated times and, for a whole lot of us, we do so with complicated minds. A billion people worldwide are living with some form of mental illness and 20% of the U.S. population has experienced a mental health crisis in the past year.Circumstances in our shared world are surely contributing to the problem: climate change and natural disasters, affordability and employment problems domestically, and people living in fear of sudden arrest and deportation. Meanwhile, tremendous strides

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00:45:57

Mike Doughty Was Recently Hospitalized for Depression...

Depresh Mode with John Moe ·

2025/12/29

It was two years into a vicious cycle of depression and Mike Doughty was falling apart. He was taking more Ambien than he had been prescribed, importing huge boxes of the stuff from India, waking up to find packs of cigarettes, candy wrappers, and pizza boxes with no memory of leaving his Memphis home to make such purchases. He was convinced something was deeply wrong with his heart even though every doctor said there wasn’t. Finally, he checked into an in-patient facility that turned out to be

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00:40:53

Tom Johnson Advised LBJ, Ran CNN, and Drove Himself...

Depresh Mode with John Moe ·

2025/12/22

The intriguing memoir Tom Johnson recently released is called Driven: A Life in Public Service from LBJ to CNN and it’s full of amazing anecdotes. Tom joined the White House in his early twenties, was the one to inform LBJ of Martin Luther King’s shooting, was a giant in newspapers and cable news, and loaned Gorbachev a pen that was used to sign the paperwork dissolving the USSR. Tom’s personal story is a little more vulnerable and fragile. He tells of experiencing a suicidal depression in a time

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00:46:40

Anger: Let’s Talk About It, Learn About It, Not Fear...

Depresh Mode with John Moe ·

2025/12/15

Anger can be a scary topic for a lot of people. It usually doesn’t feel good when you’re experiencing it and it can be associated with behaviors that are very frightening indeed. But Dr. Ryan Martin, who is one of the few academics specializing in anger and who has written two books about it, says anger is a normal and even beneficial emotion to experience. It’s your body’s way of indicating that some injustice has been done, either to you or someone else. And that’s good information to have. He

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00:35:43

Unemployment Hurts Mental Health, Horror Movies Might...

Depresh Mode with John Moe ·

2025/12/08

It’s very easy to associate your job with your own sense of self. So it makes that it can be traumatic to be one of the scores of people being laid off in today’s turbulent economy. We are joined by the New York Times’ mental health reporter, Christina Caron, who has been looking at the effect of unemployment - especially long-term unemployment - on mental health. It can lead to more severe depression, anxiety, marital problems, and substance use. She also has some great tips on what you can do for

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00:45:26

Maureen Johnson Became Friends with Her Anxiety Monster

Depresh Mode with John Moe ·

2025/12/01

Maureen Johnson loves mysteries. Loves reading classic detective fiction and loves writing mystery stories, which young readers have been gobbling up for years. Some of Maureen’s stories feature teenage sleuth Stevie Bell, who, besides having a knack for solving cold cases, deals with an anxiety disorder. It’s not all there is to Stevie, of course, but it’s definitely there and she has to manage it on an ongoing basis. Maureen tells us about Stevie and about her own recent anxiety mystery when she

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00:18:21

A Holiday Family Survival Mini-sode

Depresh Mode with John Moe ·

2025/11/26

Yes, the holidays are upon us. Getting together with family can be a wonderful, loving experience. It can also be a lot. There can be old grudges, chafing at family roles, the specter of politics might play in. We’re here to help. In This Family is a podcast produced by our host, John Moe, for Nexus Family Healing, a mental health nonprofit based in the Twin Cities. It’s all about the connections between family and mental health.In this miniature episode, that show’s host, Dr. Michelle K. Murray

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01:01:49

Esmé Weijun Wang’s Mind Convinced Her She Was Dead...

Depresh Mode with John Moe ·

2025/11/24

Cotard’s delusion, also known as Cotard’s syndrome, is an extremely rare condition where the patient believes that they are actually dead. For the bestselling author Esmé Weijun Wang, Cotard’s came along after she had already been traveling a difficult road that involved schizoaffective disorder along with a host of other mental health issues. While experiencing Cotard’s, Esmé urgently told her husband that he was dead too and so was their dog. She believed, was certain, that the life she was

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00:59:40

Is Your Mental Health Diagnosis an Identity or...

Depresh Mode with John Moe ·

2025/11/17

You may find the charges in this episode jarring: depression is not the result of a chemical imbalance, SSRIs aren’t necessarily antidepressants, and the term you use for your mental health condition isn’t scientifically valid. Sarah Fay, author of Pathological: The True Story of Six Misdiagnoses says it’s dangerous to identify with your diagnosis because it’s kind of made up and it blocks your path to recovery.A doctor told her she was “an anorexic” when Sarah was 12 years old, even though she

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00:37:33

The Personal Side of Huge Cuts to Addiction, Suicide...

Depresh Mode with John Moe ·

2025/11/10

Over half the employees at the Substance Abuse and Mental Health Services Administration (SAMHSA) who were there in January are now gone, include 12 of the 17 senior leaders. SAMHSA is in charge of distributing and administering mental health programs around the country and the cuts to both staffing and to the programs the agency serves have meant many programs addressing addiction and suicide prevention being severely hobbled or shutting down altogether. In turn, that means fewer people getting

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00:41:09

Seasonal Affective Disorder and Why It Sucks So Bad

Depresh Mode with John Moe ·

2025/11/03

When we went looking for information on the condition known as seasonal affective disorder, or SAD, one of the first things we noticed was that some people aren’t even calling it that anymore. The website for the National Alliance on Mental Illness (NAMI), for instance, uses the term “major depressive disorder with a seasonal pattern”, which means an acronym of MDDWASP. Here at Depresh Mode, we’re perfectly fine referring to it as “mud wasp”. On this episode of the show, we talk with NAMI’s chief

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