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PODCAST

Into the Impossible With Brian Keating

Big Bang Productions Inc.

Think like a physicist. Wonder like a human. Into the Impossibleis where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever askedWhat’s out there?orWhat’s next?, this is where curiosity meets clarity. Learn to think like

science natural sciences

All Episodes

114:28

Did We Find Alien Technology? Avi Loeb Explains

Into the Impossible With Brian Keating ·

2026/03/21

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥Brian Keating sits down with the ever-curious Avi Loeb for a mind-bending exploration into some of science's greatest mysteries and controversies. The conversation spans everything from the evolving understanding of comets and meteors—highlighting the false starts and surprising twists in scientific history—to the tantalizing possibilities of extraterrestrial life and the intrigue surrounding potential government

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70:40

Andy Weir Explains the Real Science of Project Hail Mary

Into the Impossible With Brian Keating ·

2026/03/20

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 In this episode of The INTO THE IMPOSSIBLE Podcast, Brian Keating sits down with Andy Weir, the bestselling author of The Martian and Project Hail Mary, to explore the real science behind one of the most ambitious science fiction stories ever written. With the upcoming film adaptation of Project Hail Mary generating excitement among fans, we dig into the physics, astrophysics, and speculative biology that make

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57:32

Meta NeuroScientist SHOCKED Me: AI Will Never Be...

Into the Impossible With Brian Keating ·

2026/03/16

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥David Sussillo spent years training neural networks at Google Brain and now leads research at Meta Reality Labs. His verdict on the path to artificial consciousness might surprise you. In this conversation, we discuss why scaling transformers alone won't produce conscious AI, how recurrent neural networks differ from the transformer architectures powering today's LLMs, the FORCE algorithm he developed

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71:32

What's The Real Value of Your Degree? Aswath Damodaran

Into the Impossible With Brian Keating ·

2026/03/09

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 Aswath Damodaran joins Brian Keating to argue that markets, universities, and financial models are all suffering the same disease — mistaking mechanical processes for genuine thinking — and explains why Nobel economists aren't billionaires, why academia is the most deserving target for disruption, and why every major asset class is now overpriced with nowhere left to hide. 00:00 Intro 00:01:37 Why

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41:26

Will AI Replace Scientists?

Into the Impossible With Brian Keating ·

2026/03/06

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥In this video, we discuss the rapidly evolving intersection of artificial intelligence and fundamental science and how AI is transforming the way physicists handle massive streams of data from modern observatories—while also explaining where its power ends and human creativity begins. Tune in for insights, surprising stories, and a behind-the-scenes look at how scientists are navigating the AI revolution

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74:48

Nick Lane: The Engine That Built Life

Into the Impossible With Brian Keating ·

2026/03/03

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 Nick Lane joins Brian Keating to argue that life is not information running on chemistry but energy in motion—showing how a single ancient metabolic “transformer” predates genes, powers mitochondria, shapes aging and cancer, constrains alien life, and reveals why today’s AI excitement echoes a solution biology discovered billions of years ago. 00:00 — Defining life vs. death; membrane potential as the boundary

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87:25

John C. Lennox: Has AI Become God? The Ultimate...

Into the Impossible With Brian Keating ·

2026/02/24

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥In this episode, I sit down with renowned Oxford mathematician, philosopher of science, and public intellectual John C. Lennox to explore the urgent questions surrounding artificial intelligence and humanity’s future. We dive into the biggest questions about AI, consciousness, truth, faith, and what it means to be human in an age of accelerating technology. If you’re curious about whether AI is humanity’s

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40:09

Can You Find God in the Laws of Physics? This is World!

Into the Impossible With Brian Keating ·

2026/02/23

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 In this conversation, I break down a provocative idea: science doesn’t “prove” ultimate truths — it eliminates what’s false. And if that’s how physics works, then the search for God (or the disproof of God) has to play by the same rules: hypotheses, predictions, and falsifiability. ------------------------------------------------------ Join this channel to get access to perks like monthly Office

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33:42

The Taboo Topic Sam Harris Won't Touch

Into the Impossible With Brian Keating ·

2026/02/17

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥In this episode, I revisit my podcast with Sam Harris. At the end of our discussion, Harris abruptly cut things short after we debated the meaning of slavery in the Bible and Talmud. Was this an honest philosophical disagreement, or an example of intellectual overstatement and rhetorical sleight-of-hand? Sam Harris is widely regarded as a leading public intellectual, yet during our 3.5-hour dialogue, I

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81:47

Nikolay Kukushkin: Slugs Have Memories

Into the Impossible With Brian Keating ·

2026/02/10

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥What can we truly learn about the brain from a kidney cell? And what do aliens and alien-like limbs have to teach us? And if language is our escape velocity moment, what does that mean for the future of AI? Nikolay Kukushkin is a scientist who believes that memory, intelligence, and even the roots of awareness may exist in places we never thought to look in. The timing of molecules in the learning of single

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75:49

Sam Arbesman: "The World is Made of Code"

Into the Impossible With Brian Keating ·

2026/02/02

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥Code. It's the closest thing humans have ever invented to magic. Write symbols on a screen, and reality emerges. Money moves, doors unlock, planes land, diseases get diagnosed, and most of us have no idea how it actually works. Today's conversation is about why code feels magical and why that feeling is both powerful and also dangerous. In a moment, you'll hear why the real risk of code is artificial

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70:56

The Mysterious Math Behind LLMs | Anil Ananthaswamy

Into the Impossible With Brian Keating ·

2026/01/23

WANTED: Developers and STEM experts! Get paid to create benchmarks and improve AI models. Sign up for Alignerr using our link: https://alignerr.com/?referral-source=briankeatingOne of the most powerful AI systems we’ve ever built is succeeding for reasons we still don’t understand. And worse, they may succeed for reasons that might lock us into the wrong future for humanity. Today’s guest is Anil Ananthaswamy, an award-winning science writer and one of the clearest thinkers on the mathematical

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71:36

Is the Universe Random or Deterministic, or Neither?...

Into the Impossible With Brian Keating ·

2026/01/12

Get My NEW Book: Focus Like a Nobel Prize Winner: https://www.amazon.com/dp/B0FN8DH6SX Andrew Jaffe Book: The Random Universe: https://www.amazon.com/Random-Universe-Models-Probability-Cosmos/dp/0300250509 Is the universe intrinsically random? In this conversation, we dive deep into why the universe may be fundamentally, intrinsically random. Whether inflation on life support, the truth behind the Hubble tension, and whether cosmology is approaching the event horizon, limits beyond which

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151:49

Max Tegmark vs. Eric Weinstein: AI, Aliens, Theories,...

Into the Impossible With Brian Keating ·

2026/01/01

Win a $100 Amazon Gift Card!Help me help you get great guests on the Into the Impossible podcast and spread the message throughout the universe. Fill out this listener survey: https://forms.gle/EUKzyE2ZqXDYJ2F47 Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 --- Enjoy this classic episode from the vault: Max Tegmark & Eric Weinstein, New Years Eve 2020! Brian Keating brings together two thought leaders at the edge of physics and philosophy: Max

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76:45

Can AI help us solve the hardest problems in...

Into the Impossible With Brian Keating ·

2025/12/30

Answer my survey to get a chance to win a $100 Amazon Gift Card!👉 https://forms.gle/uWgVRCf3BC2xxR2Y7 Please join my mailing list to get FREE notes & resources from this show! Click 👉 http://briankeating.com/yt Will AI solve future math proofs? Every time you type a password, buy something online, or send an encrypted message, you’re trusting an assumption about prime numbers: that they don’t hide an exploitable pattern. Modern cryptography depends on primes behaving “randomly enough,” yet

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49:30

Physicists Missed These Particle Tracks for Decades...

Into the Impossible With Brian Keating ·

2025/12/26

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 From the electrifying environment of high-speed particle collisions to the challenge of sifting signals from heaps of experimental noise, you'll hear how Prof Whiteson and his team are pushing boundaries. They discuss bold new algorithms capable of spotting non-standard tracks—think wild trajectories that defy classical expectations and could reveal surprises nature has kept hidden. Practical questions about

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73:04

Brian Keating’s Journey: Nobel Dreams and Cosmic...

Into the Impossible With Brian Keating ·

2025/12/24

Brian Keating sits down with Matt Gray for a wide-ranging, thoughtful, and entertaining conversation that explores the intersection of cosmology, philosophy, and mysticism. Together, they tackle some of the universe’s biggest mysteries—from the origins of the cosmos and the mechanics of the Big Bang, to the challenges and philosophy behind scientific discovery. Timestamps: 00:00 "Science, Nobel Near-Miss, and Humor" 07:26 "Passion for Science and Sharing" 12:00 "Chasing a Nobel-Worthy

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77:33

Avi Loeb: What Is 3I/ATLAS?

Into the Impossible With Brian Keating ·

2025/12/23

Please join my mailing list to get FREE notes and resources from this show, plus your chance to win a real meteorite: http://briankeating.com/yt Join us LIVE with Harvard astrophysicist Avi Loeb for the final verdict on the interstellar object 3I/ATLAS, the third confirmed visitor from beyond our solar system. We examine the newly proposed 14th anomaly: the remarkably rare alignment of 3I/ATLAS’s rotation axis within about 8 degrees of the sunward direction at distances greater than 5 AU, a

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16:31

Did You Know This Genius Changed Physics Forever?

Into the Impossible With Brian Keating ·

2025/12/22

Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 Pilgrimage mode: kilt on, chapeau secured, and I’m standing outside 14 India Street, Edinburgh — the birthplace of the physicist I’d nominate as the quiet GOAT: James Clerk Maxwell. In this solo vlog, I walk the neighbourhood where Maxwell grew up, try (and fail) to get into the small museum without a reservation, and connect the dots from Maxwell’s equations to the modern world: Wi-Fi, GPS, power grids, and

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53:05

Will It Happen Again? Comets and Asteroids Extinction...

Into the Impossible With Brian Keating ·

2025/12/15

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥Sixty-six million years ago, a single asteroid ended the reign of the dinosaurs—and Govert Schilling says the next one could be headed for us. In this episode, we uncover the science of cosmic threats, extinction risks, and whether humanity stands a chance when the sky turns deadly. Key Takeaways: 00:00 Intro 00:33 Is Earth particularly sensitive to impacts? 03:24 The role of cosmic impacts in

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