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PODCAST

BioTech Nation ... with Dr. Moira Gunn

Welcome to BIOTECH NATION !!! With understandable interviews requiring no background in science, BTN attracts a wide global audience. From everyday people looking for hope in treatments in development, to bioentrepreneurs interested in the experience of their fellow travelers, to venture capitalists looking for possibilities in cutting-edge breakthroughs, to scientists simply interested in the work of others, BioTech Nation is the voice of human endeavor, driving science to new realities for

science life sciences

All Episodes

38:02

CRISPR Dilemma... Dr. Eben Kirksey, Anthropologist &...

BioTech Nation ... with Dr. Moira Gunn ·

2024/11/06

This week on BioTech Nation, we talk with Dr. Eben Kirksey about the ethical issues behind CRISPR, the gene-editing tool that made headlines with the birth of the first “CRISPR babies” in China. Dr. Kirksey shares his experiences investigating this controversial experiment and highlights the deeper questions it raises. He stresses the importance of public dialogue, urging us to consider carefully who benefits from such powerful technologies as we shape the future of gene editing.

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12:02

AI & Better Health...Dr. Daniel Kraft, Tech Nation...

BioTech Nation ... with Dr. Moira Gunn ·

2024/10/30

This week on BioTech Nation, Dr. Daniel Kraft talks about how AI can personalize health advice using data from devices like your smartwatch. He explains how this technology can help people make better choices to stay healthy and avoid major illnesses. Dr. Kraft envisions AI as a personal health coach, offering real-time tips and reminders tailored to each person's needs.

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19:44

A Smarter Path to Curing Diseases… Dr. Avak Kahvejian...

BioTech Nation ... with Dr. Moira Gunn ·

2024/10/24

Dr. Avak Kahvejian, Founding CEO of Cellarity, explains their new approach to discovering drugs by using AI to look at how cells behave as a whole, rather than focusing on one part of the problem. This approach could lead to faster development of better treatments, such as a pill for sickle cell disease.

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16:04

Replacing Cells, Restoring Sight…Brian Culley, CEO,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/10/16

Brian Culley, CEO of Lineage Cell Therapeutics, talks about a new approach to treating diseases called whole cell replacement therapy - which replaces damaged cells with new ones. Lineage is focusing this new therapy on dry age-related macular degeneration (AMD), a leading cause of blindness, through their collaboration with Genentech..

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9:17

Multimodal Health??? Dr. Daniel Kraft, Tech Nation...

BioTech Nation ... with Dr. Moira Gunn ·

2024/10/09

Dr. Daniel Kraft, Tech Nation Health Chief Correspondent introduces "multimodal medicine", combining data like proteomics, wearables, and imaging for early disease detection. He stresses the importance of both advanced diagnostics and listening to patients' stories for effective healthcare.

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23:14

15 Billion Vaccines Doses: COVID & the Patent...

BioTech Nation ... with Dr. Moira Gunn ·

2024/10/02

Dr. Antony Taubman, the former Director of the Intellectual Property Division at the World Trade Organization, discusses the challenges faced during the COVID-19 pandemic, including the rapid development and distribution of 15 billion doses of Covid vaccines, and how international intellectual property rules influenced these efforts.

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16:54

One Pill to Stop Many Cancers??? Dr. Michael...

BioTech Nation ... with Dr. Moira Gunn ·

2024/09/11

Dr. Michael Weickert, CEO of Pacylex Pharmaceuticals, about their once-daily pill in trials now for cancer treatment - it’s already showing early indicators of success in stopping cancer growth in not just one, but a number of cancers.

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26:08

Engineering the Future of Vaccines... Dr. Robert...

BioTech Nation ... with Dr. Moira Gunn ·

2024/09/04

Dr. Robert Coleman, CEO of Codagenix, discusses their innovative approach to virus engineering, which includes developing a nasally-delivered COVID-19 vaccine that targets multiple virus proteins for broader protection. Codagenix's "rational virus design" method creates genetically stable vaccines and therapeutics, reducing the risk of harmful mutations. Their work also extends to vaccines for other diseases and viral-based cancer treatments, with the potential to significantly advance

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25:39

A Vaccine for Breast Cancer??? Dr. Amit Kumar,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/08/08

This week on BioTech Nation, Dr. Amit Kumar, President and CEO of Anixa Biosciences, talks about their work on a breast cancer vaccine which targets a protein thought only to be expressed during breastfeeding. Building on research by the Cleveland Clinic, Dr. Kumar describes ongoing human clinical trials and their potential for women with BRCA mutations.

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16:50

Are Your Genes Failing You??? Dr. Noah Davidsohn,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/31

This week on Biotech Nation, Dr. Noah Davidsohn, Co-Founder and Chief Scientific Officer of Rejuvenate Bio. The discussion centers around the regulation of protein expression and its implications for aging and health. Dr. Davidsohn explains how aging disrupts the balance of protein production, leading to various diseases. Rejuvenate Bio's gene therapies aim to restore this balance by targeting specific genes.

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25:33

Living Longer??? Dr. Peter Diamandis, XPrize Founder...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/24

This week of BioTech Nation, Dr. Peter Diamandis about his new book, "Longevity: Your Practical Playbook on Sleep, Diet, Exercise, Mindset, Medications, and Not Dying from Something Stupid". We explore his lifelong interest in extending human health span and discuss practical steps for a healthier, longer life, including sleep, diet, exercise, and mindset. Dr. Diamandis introduces the "longevity escape velocity" concept and the HealthSpan XPRIZE, which aims to reverse aging's functional

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17:48

Psychedelics... Prodrugs... What else? Dr. Sam Clark,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/17

This week on BioTech Nation, Dr. Sam Clark, CEO of Terran Biosciences, discusses prodrugs—modified drugs that improve absorption and efficacy. Also, Terran Biosciences is developing non-hallucinogenic psychedelics by blocking the serotonin 2A receptor and manufacturing psychedelics like LSD and psilocybin for research. Dr. Clark highlights Terran's innovative, tech-inspired approach to rapidly develop affordable medications.

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19:52

A Dual Approach to Combatting Hepatitis... Dr....

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/10

This week on Biotech Nation, Dr. Marianne De Backer, CEO of Vir Biotechnology talks about their Phase 2 clinical trials targeting hepatitis B and D co-infections. Vir's approach uses two drugs: tobevibart (an antibody) and elebsiran (an siRNA). These drugs prevent the virus from entering liver cells and stop it from replicating. Preliminary results are promising, showing a significant reduction in viral RNA and normalization of liver enzyme levels. Dr. De Backer also highlights Vir's

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23:18

Solving Genetic Diseases??? Dr. Neil Kumar, Founder &...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/03

This week on Biotech Nation, Dr. Neil Kumar, founder and CEO of BridgeBio Pharma. Dr. Kumar emphasizes that genetic diseases, particularly Mendelian diseases caused by single gene mutations, are solvable due to advancements in genetic measurement and understanding. He discusses BridgeBio Pharma's innovative corporate structure, which consists of multiple specialized companies under a centralized infrastructure to efficiently tackle various genetic diseases. This model allows for focused

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25:16

The Next Ozempic or Wegovy... But Without the...

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/26

What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.

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28:59

Everybody Has a Thyroid... What Could Go Wrong??? Dr....

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/19

This week we have a best of rerun with Dr. Mark Sumeray from Amolyt Pharma. Dr. Sumeray talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.

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13:38

Wearable Wonders! Dr. Daniel Kraft, Tech Nation...

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/12

This week Dr. Daniel Kraft, Tech Nation Health Chief Correspondent, discusses advanced health tech. Dr. Kraft highlights his use of wearables like the Apple Watch, Oura ring, and non-invasive blood pressure monitors. He also introduces "otherables," which track health without being worn, using devices like cameras and modified WiFi. These technologies enable continuous health monitoring and personalized care.

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32:39

FDA Approval! A New Model for BioPharma... Dr. Sam...

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/04

This week on BioTech Nation, Dr. Sam Blackman, Founder and Head of Research and Development from Day One Biopharmaceuticals, shares the story behind the FDA approval of a groundbreaking drug for the most common childhood brain cancer. Driven by the urgent need for pediatric oncology treatments, Day One's innovative approach led to the development of tovorafenib, targeting BRAF-altered pediatric low-grade gliomas. Through the FireFLY trial, they demonstrated significant efficacy, with 52% of

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13:56

Robo-Docs & VR Surgery??? Dr. Daniel Kraft, Tech...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/29

This week on BioTech Nation, Dr. Moira Gunn and Dr. Daniel Kraft discuss how robotics, AI, and virtual reality are transforming surgery. These technologies make procedures less invasive and improve training and outcomes worldwide. Future advancements may include tiny robots performing internal procedures. Security is crucial to prevent hacking of medical devices.

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16:10

No More Transfusions!!! Dr. John Scarlett, President...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/22

Dr. John Scarlett, President and CEO of Geron Corporation talks about their drug Imetelstat for myelodysplastic syndrome (MDS). MDS patients often require frequent blood transfusions, impacting their quality of life. Imetelstat, a telomerase inhibitor, aims to reduce transfusion dependence by targeting cancer cells in the bone marrow. Phase three trials showed promising results, with 40% of patients experiencing at least an 8-week transfusion-free interval.

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